MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 110449 bp
Accession: NZ_CP125336 Location: 1..110449 Organism: Klebsiella pneumoniae strain WYKP586 Replicon: plasmid pWYKP586-2
Accession: NZ_CP125336 Location: 1..110449 Organism: Klebsiella pneumoniae strain WYKP586 Replicon: plasmid pWYKP586-2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QJR21_RS28650 (1) | 1..1253 | + | 1253 | Protein_0 | four-carbon acid sugar kinase family protein | - |
| QJR21_RS28655 (1246) | 1246..1569 | + | 324 | Protein_1 | class II aldolase/adducin family protein | - |
| QJR21_RS28660 (1623) | 1623..2327 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| QJR21_RS28665 (2399) | 2399..2557 | + | 159 | Protein_3 | PAS domain-containing protein | - |
| QJR21_RS28670 (2754) | 2754..3458 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| QJR21_RS28675 (3512) | 3512..3835 | - | 324 | Protein_5 | class II aldolase/adducin family protein | - |
| QJR21_RS28680 (3828) | 3828..5077 | - | 1250 | Protein_6 | four-carbon acid sugar kinase family protein | - |
| QJR21_RS28685 (5089) | 5089..5991 | - | 903 | WP_002903955.1 | NAD(P)-dependent oxidoreductase | - |
| QJR21_RS28690 (6253) | 6253..7014 | + | 762 | WP_002210513.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| QJR21_RS28695 (7035) | 7035..7895 | - | 861 | WP_002904004.1 | Beta-lactamase SHV-2 | ARG |
| QJR21_RS28700 (8032) | 8032..8100 | + | 69 | Protein_10 | IS6 family transposase | - |
| QJR21_RS28705 (8136) | 8136..11102 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| QJR21_RS28710 (11106) | 11106..11666 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| QJR21_RS28715 (12058) | 12058..12675 | + | 618 | Protein_13 | replication protein | - |
| QJR21_RS28720 (13209) | 13209..13487 | + | 279 | WP_013213990.1 | hypothetical protein | - |
| QJR21_RS28725 (13598) | 13598..14023 | + | 426 | WP_013213989.1 | antirestriction protein | - |
| QJR21_RS28730 (14151) | 14151..14306 | + | 156 | WP_013213988.1 | hypothetical protein | - |
| QJR21_RS28735 (14352) | 14352..14648 | + | 297 | WP_013213987.1 | transcriptional regulator | - |
| QJR21_RS28740 (14752) | 14752..15633 | + | 882 | Protein_18 | IS1182 family transposase ISKpn6 | Transposase |
| QJR21_RS28745 (15883) | 15883..16764 | - | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| QJR21_RS28750 (17040) | 17040..18020 | - | 981 | WP_013213985.1 | IS481 family transposase ISKpn27 | Transposase |
| QJR21_RS28755 (18143) | 18143..18604 | - | 462 | Protein_21 | Tn3 family transposase TnpR_Tn3 | Transposase |
| QJR21_RS28760 (18656) | 18656..19360 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| QJR21_RS28765 (19425) | 19425..20597 | - | 1173 | Protein_23 | transposase | - |
| QJR21_RS28770 (20672) | 20672..21340 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| QJR21_RS28775 (21376) | 21376..21612 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| QJR21_RS28780 (21609) | 21609..21971 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| QJR21_RS28785 (21989) | 21989..23683 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| QJR21_RS28790 (23735) | 23735..24157 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| QJR21_RS28795 (24193) | 24193..24468 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| QJR21_RS28800 (24482) | 24482..24832 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| QJR21_RS28805 (24904) | 24904..25338 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| QJR21_RS28810 (25417) | 25417..26421 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| QJR21_RS28815 (26701) | 26701..26973 | - | 273 | Protein_33 | IS5 family transposase ISPan1 | Transposase |
| QJR21_RS28825 (27955) | 27955..28977 | - | 1023 | WP_000361404.1 | helicase UvrD | - |
| QJR21_RS28830 (28962) | 28962..30524 | - | 1563 | WP_004206609.1 | AAA family ATPase | - |
| QJR21_RS28835 (30598) | 30598..31014 | - | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| QJR21_RS28840 (31011) | 31011..31241 | - | 231 | WP_001261282.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| QJR21_RS28845 (31198) | 31198..31659 | + | 462 | WP_014343465.1 | hypothetical protein | - |
| QJR21_RS28850 (31820) | 31820..32764 | + | 945 | WP_011977810.1 | hypothetical protein | - |
| QJR21_RS28855 (32801) | 32801..33193 | + | 393 | WP_011977811.1 | hypothetical protein | - |
| QJR21_RS28860 (33251) | 33251..33772 | + | 522 | WP_013214008.1 | hypothetical protein | - |
| QJR21_RS28865 (33818) | 33818..34021 | + | 204 | WP_011977813.1 | hypothetical protein | - |
| QJR21_RS28870 (34051) | 34051..35055 | + | 1005 | WP_011977814.1 | hypothetical protein | - |
| QJR21_RS28875 (35239) | 35239..36018 | + | 780 | WP_013214009.1 | site-specific integrase | - |
| QJR21_RS28880 (36064) | 36064..36321 | - | 258 | WP_013214010.1 | hypothetical protein | - |
| QJR21_RS28885 (36450) | 36450..36563 | - | 114 | WP_014343462.1 | hypothetical protein | - |
| QJR21_RS28890 (37099) | 37099..37965 | + | 867 | WP_004118283.1 | replication initiation protein | - |
| QJR21_RS28895 (39075) | 39075..40280 | + | 1206 | WP_011977818.1 | AAA family ATPase | - |
| QJR21_RS28900 (40280) | 40280..41254 | + | 975 | WP_217289798.1 | ParB family protein | - |
| QJR21_RS28905 (41336) | 41336..42607 | - | 1272 | WP_232196806.1 | Y-family DNA polymerase | - |
| QJR21_RS28910 (42607) | 42607..43038 | - | 432 | WP_001568036.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| QJR21_RS28915 (43445) | 43445..44932 | + | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| QJR21_RS28920 (45181) | 45181..46152 | + | 972 | WP_004152353.1 | plasmid segregation protein ParM | - |
| QJR21_RS28925 (46155) | 46155..46826 | + | 672 | WP_013214012.1 | plasmid partitioning/stability family protein | - |
| QJR21_RS28930 (46889) | 46889..47119 | + | 231 | WP_001568040.1 | hypothetical protein | - |
| QJR21_RS28935 (47315) | 47315..47484 | + | 170 | Protein_57 | hypothetical protein | - |
| QJR21_RS28940 (47556) | 47556..48257 | + | 702 | WP_001568041.1 | DNA methylase | - |
| QJR21_RS28945 (48257) | 48257..48478 | + | 222 | WP_001568042.1 | hypothetical protein | - |
| QJR21_RS28950 (48488) | 48488..48907 | + | 420 | WP_001568043.1 | DUF1380 domain-containing protein | - |
| QJR21_RS28955 (48961) | 48961..49728 | + | 768 | WP_013214013.1 | hypothetical protein | - |
| QJR21_RS28960 (50409) | 50409..50837 | + | 429 | WP_001568045.1 | antirestriction protein | - |
| QJR21_RS28965 (50880) | 50880..51386 | + | 507 | WP_013214014.1 | antirestriction protein ArdA | - |
| QJR21_RS28970 (51429) | 51429..51620 | + | 192 | WP_001568047.1 | hypothetical protein | - |
| QJR21_RS28975 (51808) | 51808..52062 | + | 255 | WP_011977779.1 | DNA polymerase III subunit theta | - |
| QJR21_RS28980 (52097) | 52097..52417 | + | 321 | WP_001568049.1 | hypothetical protein | - |
| QJR21_RS28985 (53097) | 53097..53324 | + | 228 | WP_001568050.1 | hypothetical protein | - |
| QJR21_RS28990 (53416) | 53416..53646 | + | 231 | WP_001568051.1 | hypothetical protein | - |
| QJR21_RS28995 (53698) | 53698..55053 | + | 1356 | WP_014343515.1 | DUF3560 domain-containing protein | - |
| QJR21_RS29000 (55101) | 55101..55664 | + | 564 | WP_283155684.1 | methyltransferase | - |
| QJR21_RS29005 (56497) | 56497..57039 | + | 543 | WP_014343512.1 | single-stranded DNA-binding protein | - |
| QJR21_RS29010 (57088) | 57088..57336 | + | 249 | WP_001568055.1 | DUF905 domain-containing protein | - |
| QJR21_RS29015 (57406) | 57406..59463 | + | 2058 | WP_217289800.1 | ParB/RepB/Spo0J family partition protein | - |
| QJR21_RS29020 (59508) | 59508..59939 | + | 432 | WP_001568057.1 | conjugation system SOS inhibitor PsiB | - |
| QJR21_RS29025 (59936) | 59936..60664 | + | 729 | WP_001568058.1 | plasmid SOS inhibition protein A | - |
| QJR21_RS29030 (60661) | 60661..60987 | + | 327 | WP_013023807.1 | hypothetical protein | - |
| QJR21_RS29035 (61043) | 61043..61417 | + | 375 | WP_014343510.1 | hypothetical protein | - |
| QJR21_RS29040 (61587) | 61587..61739 | + | 153 | WP_004150508.1 | DUF5431 family protein | - |
| QJR21_RS29045 (61684) | 61684..61803 | + | 120 | WP_159376494.1 | type I toxin-antitoxin system Hok family toxin | - |
| QJR21_RS29050 (62496) | 62496..62768 | + | 273 | WP_040245921.1 | hypothetical protein | - |
| QJR21_RS29055 (62765) | 62765..63115 | + | 351 | WP_040245917.1 | hypothetical protein | - |
| QJR21_RS29060 (63130) | 63130..63447 | + | 318 | WP_014343505.1 | hypothetical protein | - |
| QJR21_RS29065 (64288) | 64288..64644 | + | 357 | WP_014343501.1 | hypothetical protein | - |
| QJR21_RS29070 (64705) | 64705..64917 | + | 213 | WP_014343500.1 | hypothetical protein | - |
| QJR21_RS29075 (64928) | 64928..65152 | + | 225 | WP_014343499.1 | hypothetical protein | - |
| QJR21_RS29080 (65233) | 65233..65553 | + | 321 | WP_014343498.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| QJR21_RS29085 (65543) | 65543..65821 | + | 279 | WP_004152721.1 | helix-turn-helix transcriptional regulator | - |
| QJR21_RS29090 (65825) | 65825..65929 | + | 105 | Protein_88 | transcriptional regulator | - |
| QJR21_RS29095 (66758) | 66758..67579 | + | 822 | WP_004152492.1 | DUF932 domain-containing protein | - |
| QJR21_RS29100 (67612) | 67612..67941 | + | 330 | WP_013214015.1 | DUF5983 family protein | - |
| QJR21_RS29105 (67974) | 67974..68459 | - | 486 | WP_014343495.1 | hypothetical protein | VF |
| QJR21_RS29110 (68850) | 68850..69266 | + | 417 | WP_014343494.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| QJR21_RS29115 (69466) | 69466..70203 | + | 738 | WP_154244330.1 | conjugal transfer protein TrbJ | - |
| QJR21_RS29120 (70318) | 70318..70524 | + | 207 | WP_171773970.1 | TraY domain-containing protein | - |
| QJR21_RS29125 (70586) | 70586..70954 | + | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| QJR21_RS29130 (70968) | 70968..71273 | + | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| QJR21_RS29135 (71293) | 71293..71658 | + | 366 | Protein_97 | type IV conjugative transfer system protein TraE | - |
| QJR21_RS29140 (71713) | 71713..72057 | - | 345 | Protein_98 | IS6 family transposase IS26 | Transposase |
| QJR21_RS29145 (72109) | 72109..72813 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| QJR21_RS29150 (72838) | 72838..73038 | + | 201 | WP_072354025.1 | hypothetical protein | - |
| QJR21_RS29155 (73058) | 73058..73804 | + | 747 | WP_000205770.1 | conjugal transfer pilus acetylase TraX | - |
| QJR21_RS29160 (73859) | 73859..74419 | + | 561 | WP_000139328.1 | fertility inhibition protein FinO | - |
| QJR21_RS29165 (74551) | 74551..74751 | + | 201 | WP_015059022.1 | hypothetical protein | - |
| QJR21_RS29170 (75137) | 75137..75736 | + | 600 | WP_032083981.1 | PIN domain-containing protein | - |
| QJR21_RS29175 (75798) | 75798..76130 | + | 333 | WP_152916585.1 | hypothetical protein | - |
| - (76331) | 76331..76390 | - | 60 | NuclAT_0 | - | Antitoxin Detail |
| - (76331) | 76331..76390 | - | 60 | NuclAT_0 | - | Antitoxin Detail |
| - (76331) | 76331..76390 | - | 60 | NuclAT_0 | - | Antitoxin Detail |
| - (76331) | 76331..76390 | - | 60 | NuclAT_0 | - | Antitoxin Detail |
| QJR21_RS29180 (76435) | 76435..76584 | + | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| QJR21_RS29185 (76868) | 76868..77116 | + | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
| QJR21_RS29190 (77361) | 77361..77435 | + | 75 | WP_001375168.1 | RepA leader peptide Tap | - |
| QJR21_RS29195 (77428) | 77428..78285 | + | 858 | WP_032495102.1 | incFII family plasmid replication initiator RepA | - |
| QJR21_RS29200 (79224) | 79224..79877 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| QJR21_RS29205 (79970) | 79970..80227 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| QJR21_RS29210 (80160) | 80160..80561 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| QJR21_RS29215 (80810) | 80810..81225 | + | 416 | Protein_113 | IS1 family transposase IS1R | Transposase |
| QJR21_RS29220 (81261) | 81261..81806 | - | 546 | Protein_114 | Tn3 family transposase TnpA_Tn3 | Transposase |
| QJR21_RS29225 (81872) | 81872..82576 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| QJR21_RS29230 (82640) | 82640..82756 | + | 117 | Protein_116 | hypothetical protein | - |
| QJR21_RS29235 (82789) | 82789..83757 | + | 969 | WP_013362812.1 | IS5 family transposase IS903B | Transposase |
| QJR21_RS29240 (83814) | 83814..84911 | + | 1098 | Protein_118 | TonB-dependent receptor | - |
| QJR21_RS29245 (84979) | 84979..85455 | - | 477 | Protein_119 | PAS domain-containing protein | - |
| QJR21_RS29250 (85508) | 85508..86212 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| QJR21_RS29255 (86276) | 86276..86566 | + | 291 | Protein_121 | ATP-dependent endonuclease | - |
| QJR21_RS29260 (86551) | 86551..87573 | + | 1023 | WP_000361404.1 | helicase UvrD | - |
| QJR21_RS29265 (87829) | 87829..88526 | + | 698 | WP_223174630.1 | IS1 family transposase ISKpn14 | Transposase |
| QJR21_RS29270 (88555) | 88555..88827 | + | 273 | Protein_124 | IS5 family transposase ISPan1 | Transposase |
| QJR21_RS29275 (89107) | 89107..90111 | - | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| QJR21_RS29280 (90190) | 90190..90624 | - | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| QJR21_RS29285 (90696) | 90696..91046 | + | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| QJR21_RS29290 (91060) | 91060..91335 | + | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| QJR21_RS29295 (91371) | 91371..91793 | + | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| QJR21_RS29300 (91845) | 91845..93539 | + | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| QJR21_RS29305 (93557) | 93557..93919 | + | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| QJR21_RS29310 (93916) | 93916..94152 | + | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| QJR21_RS29315 (94188) | 94188..94856 | + | 669 | WP_001300294.1 | putative signaling protein | VF |
| QJR21_RS29320 (94931) | 94931..96103 | + | 1173 | Protein_134 | transposase | - |
| QJR21_RS29325 (96168) | 96168..96872 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| QJR21_RS29330 (96924) | 96924..97385 | + | 462 | Protein_136 | Tn3 family transposase TnpR_Tn3 | Transposase |
| QJR21_RS29335 (97508) | 97508..98488 | + | 981 | WP_013213985.1 | IS481 family transposase ISKpn27 | Transposase |
| QJR21_RS29340 (98764) | 98764..99645 | + | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| QJR21_RS29345 (99895) | 99895..100776 | - | 882 | Protein_139 | IS1182 family transposase ISKpn6 | Transposase |
| QJR21_RS29350 (100880) | 100880..101176 | - | 297 | WP_013213987.1 | transcriptional regulator | - |
| QJR21_RS29355 (101222) | 101222..101377 | - | 156 | WP_013213988.1 | hypothetical protein | - |
| QJR21_RS29360 (101505) | 101505..101930 | - | 426 | WP_013213989.1 | antirestriction protein | - |
| QJR21_RS29365 (102041) | 102041..102319 | - | 279 | WP_013213990.1 | hypothetical protein | - |
| QJR21_RS29370 (102853) | 102853..103470 | - | 618 | Protein_144 | replication protein | - |
| QJR21_RS29375 (103861) | 103861..104421 | + | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| QJR21_RS29380 (104425) | 104425..107391 | + | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| QJR21_RS29385 (107427) | 107427..107495 | - | 69 | Protein_147 | IS6 family transposase | - |
| QJR21_RS29390 (107632) | 107632..108492 | + | 861 | WP_002904004.1 | Beta-lactamase SHV-2 | ARG |
| QJR21_RS29395 (108513) | 108513..109274 | - | 762 | WP_002210513.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| QJR21_RS29400 (109536) | 109536..110438 | + | 903 | WP_002903955.1 | NAD(P)-dependent oxidoreductase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|