MGE detailed information
MGE type: Conjugative plasmid MGE length: 80091 bp
Accession: NZ_CP123257 Location: 1..80091 Organism: Escherichia coli strain YZMc17-1 Replicon: plasmid pYZMc17-1_NDM-5_80K
Accession: NZ_CP123257 Location: 1..80091 Organism: Escherichia coli strain YZMc17-1 Replicon: plasmid pYZMc17-1_NDM-5_80K
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| N4680_RS24030 (1) | 1..858 | + | 858 | WP_032495102.1 | incFII family plasmid replication initiator RepA | - |
| N4680_RS24035 (1559) | 1559..1699 | + | 141 | WP_001333237.1 | hypothetical protein | - |
| N4680_RS24040 (1797) | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| N4680_RS24045 (2543) | 2543..2800 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| N4680_RS24050 (2733) | 2733..3134 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| N4680_RS24055 (3383) | 3383..3798 | + | 416 | Protein_5 | IS1 family transposase IS1R | Transposase |
| N4680_RS24060 (3834) | 3834..4379 | - | 546 | Protein_6 | Tn3 family transposase TnpA_Tn3 | Transposase |
| N4680_RS24065 (4445) | 4445..5149 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| N4680_RS24070 (5208) | 5208..5342 | + | 135 | WP_023408307.1 | divalent cation tolerance protein CutA | - |
| N4680_RS24075 (5347) | 5347..5721 | + | 375 | Protein_9 | protein-disulfide reductase DsbD family protein | - |
| N4680_RS24080 (5821) | 5821..6378 | + | 558 | Protein_10 | twin-arginine translocation (TAT) pathway signal sequence domain protein | - |
| N4680_RS24085 (6389) | 6389..7027 | - | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| N4680_RS24090 (7032) | 7032..7397 | - | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| N4680_RS24095 (7401) | 7401..8213 | - | 813 | WP_023408309.1 | Metallo-beta-lactamase type 2 | ARG |
| N4680_RS24100 (8448) | 8448..9428 | + | 981 | WP_000019402.1 | IS5 family transposase IS5D | Transposase |
| N4680_RS24105 (9537) | 9537..10481 | - | 945 | WP_100183899.1 | IS30 family transposase ISAba125 | Transposase |
| N4680_RS24110 (10758) | 10758..13466 | - | 2709 | Protein_16 | Tn3 family transposase TnpA_IS3000 | Transposase |
| N4680_RS24115 (13638) | 13638..14837 | - | 1200 | WP_000948429.1 | IS91 family transposase ISSbo1 | Transposase |
| N4680_RS24120 (14847) | 14847..15035 | - | 189 | WP_000957857.1 | hypothetical protein | - |
| N4680_RS24125 (15127) | 15127..15663 | + | 537 | WP_064441864.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| N4680_RS24130 (15846) | 15846..16706 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| N4680_RS24135 (16876) | 16876..17631 | + | 756 | WP_262951854.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase | ARG |
| N4680_RS24140 (17712) | 17712..18026 | - | 315 | Protein_22 | hypothetical protein | - |
| N4680_RS24145 (18081) | 18081..18785 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| N4680_RS24150 (18851) | 18851..18916 | + | 66 | Protein_24 | IS1 family transposase | - |
| N4680_RS24155 (20365) | 20365..20599 | + | 235 | Protein_25 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| N4680_RS24160 (20727) | 20727..20930 | + | 204 | Protein_26 | hypothetical protein | - |
| N4680_RS24165 (21131) | 21131..21481 | - | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| N4680_RS24170 (21484) | 21484..22446 | - | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| N4680_RS24175 (22593) | 22593..22886 | + | 294 | WP_032146011.1 | hypothetical protein | - |
| N4680_RS24180 (22963) | 22963..23646 | + | 684 | WP_000085883.1 | DNA methylase | - |
| N4680_RS24185 (23647) | 23647..23868 | + | 222 | WP_001104881.1 | hypothetical protein | - |
| N4680_RS24190 (23882) | 23882..24316 | + | 435 | WP_000274503.1 | DUF1380 family protein | - |
| N4680_RS24195 (24367) | 24367..24933 | + | 567 | Protein_33 | hypothetical protein | - |
| N4680_RS24200 (24992) | 24992..25789 | - | 798 | WP_000544830.1 | IS21 family transposase IS21 | Transposase |
| N4680_RS24205 (25789) | 25789..26961 | - | 1173 | WP_000952373.1 | IS21 family transposase IS21 | Transposase |
| N4680_RS24210 (27062) | 27062..27277 | + | 216 | Protein_36 | hypothetical protein | - |
| N4680_RS24215 (27695) | 27695..28120 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| N4680_RS24220 (28167) | 28167..28589 | + | 423 | WP_000271762.1 | DUF1380 family protein | - |
| N4680_RS24225 (28586) | 28586..28777 | + | 192 | WP_001027493.1 | hypothetical protein | - |
| N4680_RS24230 (29091) | 29091..30758 | - | 1668 | WP_262951817.1 | group II intron reverse transcriptase/maturase | - |
| N4680_RS24235 (31487) | 31487..31641 | - | 155 | Protein_41 | hypothetical protein | - |
| N4680_RS24240 (32158) | 32158..32388 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| N4680_RS24245 (32440) | 32440..33801 | + | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| N4680_RS24250 (33848) | 33848..34411 | + | 564 | WP_015059007.1 | class I SAM-dependent methyltransferase | - |
| N4680_RS24255 (34497) | 34497..34952 | - | 456 | Protein_45 | hypothetical protein | - |
| N4680_RS24260 (35254) | 35254..35781 | + | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| N4680_RS24265 (35839) | 35839..36072 | + | 234 | WP_000006003.1 | DUF905 family protein | - |
| N4680_RS24270 (36133) | 36133..38156 | + | 2024 | Protein_48 | ParB/RepB/Spo0J family partition protein | - |
| N4680_RS24275 (38225) | 38225..38659 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| N4680_RS24280 (38656) | 38656..39418 | + | 763 | Protein_50 | plasmid SOS inhibition protein A | - |
| N4680_RS24285 (39396) | 39396..39575 | - | 180 | WP_001309233.1 | hypothetical protein | - |
| - (39387) | 39387..39611 | + | 225 | NuclAT_0 | - | - |
| - (39387) | 39387..39611 | + | 225 | NuclAT_0 | - | - |
| - (39387) | 39387..39611 | + | 225 | NuclAT_0 | - | - |
| - (39387) | 39387..39611 | + | 225 | NuclAT_0 | - | - |
| N4680_RS24290 (39597) | 39597..39746 | + | 150 | Protein_52 | plasmid maintenance protein Mok | - |
| N4680_RS24295 (39688) | 39688..39813 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| N4680_RS24300 (40132) | 40132..40428 | - | 297 | Protein_54 | hypothetical protein | - |
| N4680_RS24305 (40728) | 40728..41024 | + | 297 | WP_001272251.1 | hypothetical protein | - |
| N4680_RS24310 (41135) | 41135..41956 | + | 822 | WP_001234445.1 | DUF932 domain-containing protein | - |
| N4680_RS24315 (42253) | 42253..42900 | - | 648 | WP_015059008.1 | hypothetical protein | VF |
| N4680_RS24320 (43177) | 43177..43560 | + | 384 | WP_000124981.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| N4680_RS24325 (43751) | 43751..44437 | + | 687 | WP_015059009.1 | PAS domain-containing protein | - |
| N4680_RS24330 (44531) | 44531..44758 | + | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| N4680_RS24335 (44792) | 44792..45157 | + | 366 | WP_021519752.1 | type IV conjugative transfer system pilin TraA | - |
| N4680_RS24340 (45172) | 45172..45483 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| N4680_RS24345 (45505) | 45505..46071 | + | 567 | WP_000399794.1 | type IV conjugative transfer system protein TraE | - |
| N4680_RS24350 (46058) | 46058..46786 | + | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| N4680_RS24355 (46786) | 46786..48213 | + | 1428 | WP_032297072.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| N4680_RS24360 (48203) | 48203..48793 | + | 591 | WP_000002778.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| N4680_RS24365 (48780) | 48780..48977 | + | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| N4680_RS24370 (48989) | 48989..49240 | + | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
| N4680_RS24375 (49237) | 49237..49752 | + | 516 | WP_000809902.1 | type IV conjugative transfer system lipoprotein TraV | - |
| N4680_RS24380 (49887) | 49887..50108 | + | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| N4680_RS24385 (50268) | 50268..52895 | + | 2628 | WP_015059012.1 | type IV secretion system protein TraC | - |
| N4680_RS24390 (52892) | 52892..53278 | + | 387 | WP_015059013.1 | type-F conjugative transfer system protein TrbI | - |
| N4680_RS24395 (53275) | 53275..53907 | + | 633 | WP_001203735.1 | type-F conjugative transfer system protein TraW | - |
| N4680_RS24400 (53904) | 53904..54896 | + | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| N4680_RS24405 (54923) | 54923..55231 | + | 309 | WP_000412447.1 | hypothetical protein | - |
| N4680_RS24410 (55294) | 55294..55815 | + | 522 | WP_015059014.1 | hypothetical protein | - |
| N4680_RS24415 (55842) | 55842..56480 | + | 639 | WP_000087532.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| N4680_RS24420 (56477) | 56477..56848 | + | 372 | WP_000056336.1 | hypothetical protein | - |
| N4680_RS24425 (56874) | 56874..57296 | + | 423 | WP_001229309.1 | HNH endonuclease signature motif containing protein | - |
| N4680_RS24430 (57293) | 57293..59143 | + | 1851 | WP_015059015.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| N4680_RS24435 (59170) | 59170..59427 | + | 258 | WP_053913405.1 | conjugal transfer protein TrbE | - |
| N4680_RS24440 (59420) | 59420..60163 | + | 744 | WP_015059017.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| N4680_RS24445 (60324) | 60324..60560 | + | 237 | WP_000270010.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| N4680_RS24450 (60547) | 60547..61092 | + | 546 | WP_000059817.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| N4680_RS24455 (61082) | 61082..61396 | + | 315 | WP_001384255.1 | P-type conjugative transfer protein TrbJ | - |
| N4680_RS24460 (61350) | 61350..61742 | + | 393 | WP_000126338.1 | F-type conjugal transfer protein TrbF | - |
| N4680_RS24465 (61729) | 61729..63102 | + | 1374 | WP_000944325.1 | conjugal transfer pilus assembly protein TraH | - |
| N4680_RS24470 (63099) | 63099..65915 | + | 2817 | WP_015059018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| N4680_RS24475 (65948) | 65948..66469 | + | 522 | WP_000632668.1 | conjugal transfer entry exclusion protein TraS | - |
| N4680_RS24480 (66494) | 66494..67225 | + | 732 | WP_021559024.1 | conjugal transfer complement resistance protein TraT | - |
| N4680_RS24485 (67428) | 67428..68165 | + | 738 | WP_015059020.1 | hypothetical protein | - |
| N4680_RS24490 (68216) | 68216..70432 | + | 2217 | WP_059274178.1 | type IV conjugative transfer system coupling protein TraD | - |
| N4680_RS24495 (70432) | 70432..75702 | + | 5271 | WP_262951736.1 | Multifunctional conjugation protein TraI | Relaxase |
| N4680_RS24500 (75722) | 75722..76468 | + | 747 | WP_000205770.1 | conjugal transfer pilus acetylase TraX | - |
| N4680_RS24505 (76523) | 76523..77083 | + | 561 | WP_000139328.1 | fertility inhibition protein FinO | - |
| N4680_RS24510 (77215) | 77215..77415 | + | 201 | WP_015059022.1 | hypothetical protein | - |
| N4680_RS24515 (77801) | 77801..78400 | + | 600 | WP_032083981.1 | PIN domain-containing protein | - |
| N4680_RS24520 (78462) | 78462..78794 | + | 333 | WP_152916585.1 | hypothetical protein | - |
| - (78995) | 78995..79054 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (78995) | 78995..79054 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (78995) | 78995..79054 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (78995) | 78995..79054 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| N4680_RS24525 (79099) | 79099..79248 | + | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| N4680_RS24530 (79532) | 79532..79780 | + | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|