MGE detailed information
MGE type: Conjugative plasmid MGE length: 125049 bp
Accession: NZ_CP122518 Location: 1..125049 Organism: Escherichia coli strain MY1-8 Replicon: plasmid pSCMY2
Accession: NZ_CP122518 Location: 1..125049 Organism: Escherichia coli strain MY1-8 Replicon: plasmid pSCMY2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QCL60_RS22895 (1194) | 1194..1373 | - | 180 | Protein_0 | integrase core domain-containing protein | - |
| QCL60_RS22900 (1512) | 1512..2711 | + | 1200 | Protein_1 | IS3 family transposase IS629 | Transposase |
| QCL60_RS22905 (2859) | 2859..3184 | - | 326 | Protein_2 | IS3 family transposase ISLad1 | Transposase |
| QCL60_RS22910 (3230) | 3230..3570 | + | 341 | Protein_3 | IS3 family transposase | - |
| QCL60_RS22915 (4165) | 4165..5352 | + | 1188 | WP_000928804.1 | efflux RND transporter periplasmic adaptor subunit | - |
| QCL60_RS22920 (5349) | 5349..7289 | + | 1941 | WP_000733250.1 | Macrolide export ATP-binding/permease protein MacB | VF |
| QCL60_RS22925 (7293) | 7293..8600 | + | 1308 | Protein_6 | efflux transporter outer membrane subunit | - |
| QCL60_RS22930 (8622) | 8622..9239 | - | 618 | Protein_7 | ISNCY family transposase | - |
| QCL60_RS22935 (9165) | 9165..9320 | + | 156 | WP_279976907.1 | hypothetical protein | - |
| QCL60_RS22940 (9603) | 9603..9752 | - | 150 | Protein_9 | IS3 family transposase IS2 | Transposase |
| QCL60_RS22945 (9930) | 9930..11123 | - | 1194 | WP_000450494.1 | GTP-binding protein | - |
| QCL60_RS22950 (12365) | 12365..13102 | - | 738 | Protein_11 | IS3 family transposase IS2 | Transposase |
| QCL60_RS22955 (13155) | 13155..14317 | + | 1163 | WP_088846059.1 | IS3 family transposase ISEc17 | Transposase |
| QCL60_RS22960 (14334) | 14334..14854 | - | 521 | Protein_13 | IS3 family transposase IS2 | Transposase |
| QCL60_RS22965 (15479) | 15479..15772 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| QCL60_RS22970 (15830) | 15830..16029 | - | 200 | Protein_15 | lysis protein | - |
| QCL60_RS22975 (16583) | 16583..17607 | + | 1025 | Protein_16 | integrase core domain-containing protein | - |
| QCL60_RS22980 (18918) | 18918..20033 | + | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| QCL60_RS22985 (20173) | 20173..23832 | + | 3660 | WP_001389363.1 | Multidrug efflux ATP-binding/permease protein | VF |
| QCL60_RS22990 (23936) | 23936..25165 | + | 1230 | WP_000933678.1 | Enterochelin esterase | VF |
| QCL60_RS22995 (25250) | 25250..26206 | + | 957 | WP_000271274.1 | hypothetical protein | VF |
| QCL60_RS23000 (26251) | 26251..28428 | - | 2178 | WP_001222186.1 | Ferric enterobactin receptor | VF |
| QCL60_RS23005 (29294) | 29294..30328 | - | 1035 | WP_001190234.1 | 3-deoxy-7-phosphoheptulonate synthase | - |
| QCL60_RS23010 (30509) | 30509..30810 | + | 302 | Protein_23 | hypothetical protein | - |
| QCL60_RS23015 (30888) | 30888..31181 | - | 294 | WP_000269327.1 | DUF6404 family protein | - |
| QCL60_RS23020 (31349) | 31349..31474 | - | 126 | Protein_25 | type II toxin-antitoxin system toxin YacB | - |
| QCL60_RS23025 (31474) | 31474..31742 | - | 269 | Protein_26 | type II toxin-antitoxin system antitoxin YacA | - |
| QCL60_RS23030 (32353) | 32353..33627 | + | 1275 | WP_000489609.1 | HlyD family secretion protein | - |
| QCL60_RS23035 (33620) | 33620..35716 | + | 2097 | WP_000184924.1 | microcin H47 export transporter peptidase/ATP-binding subunit MchF | - |
| QCL60_RS23040 (35886) | 35886..36197 | - | 312 | WP_001259758.1 | colicin V | - |
| QCL60_RS23045 (36175) | 36175..36411 | - | 237 | WP_001323890.1 | colicin V immunity protein | - |
| QCL60_RS23050 (36530) | 36530..36973 | + | 444 | WP_001323891.1 | dehydrogenase | - |
| QCL60_RS23055 (36945) | 36945..37349 | + | 405 | WP_001389361.1 | hypothetical protein | - |
| QCL60_RS23060 (37351) | 37351..37620 | + | 270 | WP_000379710.1 | SemiSWEET transporter | - |
| QCL60_RS23065 (37617) | 37617..38597 | + | 981 | WP_001017346.1 | NAD(P)-binding domain-containing protein | - |
| QCL60_RS23070 (38673) | 38673..39053 | + | 381 | WP_001171523.1 | IS66 family transposase ISEc8 | Transposase |
| QCL60_RS23075 (39050) | 39050..39397 | + | 348 | WP_000612591.1 | IS66 family transposase ISEc8 | Transposase |
| QCL60_RS23080 (39447) | 39447..40307 | + | 861 | Protein_37 | IS66 family transposase ISEc8 | Transposase |
| QCL60_RS23085 (40343) | 40343..43279 | - | 2937 | Protein_38 | Tn3 family transposase TnpA_Tn3 | Transposase |
| QCL60_RS23090 (43319) | 43319..44023 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| QCL60_RS23095 (44088) | 44088..44375 | - | 288 | Protein_40 | nucleotidyltransferase domain-containing protein | - |
| QCL60_RS23100 (44506) | 44506..44979 | - | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| QCL60_RS23105 (45137) | 45137..46150 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| QCL60_RS23110 (46353) | 46353..46703 | + | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| QCL60_RS23115 (46829) | 46829..47011 | + | 183 | Protein_44 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| QCL60_RS23120 (47066) | 47066..47770 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| QCL60_RS23125 (48087) | 48087..48269 | + | 183 | Protein_46 | Tn3 family transposase TnpR_Tn3 | Transposase |
| QCL60_RS23130 (48312) | 48312..49016 | - | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| QCL60_RS23135 (49007) | 49007..49282 | + | 276 | WP_049195398.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| QCL60_RS23140 (49315) | 49315..49533 | + | 219 | Protein_49 | IS1 family transposase | - |
| QCL60_RS23145 (49565) | 49565..49780 | - | 216 | WP_061583825.1 | hypothetical protein | - |
| QCL60_RS23150 (50483) | 50483..50782 | - | 300 | Protein_51 | incFII family plasmid replication initiator RepA | - |
| QCL60_RS23155 (50869) | 50869..51615 | - | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| QCL60_RS23160 (51630) | 51630..53171 | - | 1542 | WP_001298859.1 | IS21 family transposase ISEc12 | Transposase |
| QCL60_RS23165 (53363) | 53363..53926 | - | 564 | Protein_54 | plasmid replication initiator RepA | - |
| QCL60_RS23170 (53919) | 53919..54401 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| QCL60_RS23175 (54394) | 54394..54441 | - | 48 | WP_229471593.1 | hypothetical protein | - |
| QCL60_RS23180 (54432) | 54432..54683 | + | 252 | WP_223195197.1 | replication protein RepA | - |
| QCL60_RS23185 (54700) | 54700..54957 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| QCL60_RS23190 (55241) | 55241..55390 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (55434) | 55434..55495 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (55434) | 55434..55495 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (55434) | 55434..55495 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (55434) | 55434..55495 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| QCL60_RS23195 (55751) | 55751..55825 | - | 75 | Protein_60 | endonuclease | - |
| QCL60_RS23200 (56071) | 56071..56283 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| QCL60_RS23205 (56419) | 56419..56979 | - | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| QCL60_RS23210 (57082) | 57082..57942 | - | 861 | WP_000704514.1 | Quorum-quenching protein AidA | VF |
| QCL60_RS23215 (58001) | 58001..58747 | - | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| QCL60_RS23220 (58767) | 58767..64037 | - | 5271 | WP_000986962.1 | Multifunctional conjugation protein TraI | Relaxase |
| QCL60_RS23225 (64119) | 64119..64346 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| QCL60_RS23230 (64346) | 64346..64744 | + | 399 | WP_000911313.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| QCL60_RS23235 (64753) | 64753..66906 | - | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| QCL60_RS23240 (67159) | 67159..67890 | - | 732 | WP_023565183.1 | conjugal transfer complement resistance protein TraT | - |
| QCL60_RS23245 (67922) | 67922..68419 | - | 498 | WP_000605857.1 | entry exclusion protein | - |
| QCL60_RS23250 (68435) | 68435..71257 | - | 2823 | WP_001007018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| QCL60_RS23255 (71254) | 71254..72627 | - | 1374 | WP_001517790.1 | conjugal transfer pilus assembly protein TraH | - |
| QCL60_RS23260 (72627) | 72627..73007 | - | 381 | WP_001389370.1 | F-type conjugal transfer protein TrbF | - |
| QCL60_RS23265 (72994) | 72994..73335 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| QCL60_RS23270 (73265) | 73265..73810 | - | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| QCL60_RS23275 (73797) | 73797..74081 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| QCL60_RS23280 (74162) | 74162..74476 | + | 315 | WP_001324103.1 | hypothetical protein | - |
| QCL60_RS23285 (74478) | 74478..74825 | - | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| QCL60_RS23290 (74841) | 74841..75584 | - | 744 | WP_001030393.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| QCL60_RS23295 (75577) | 75577..75834 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| QCL60_RS23300 (75861) | 75861..77669 | - | 1809 | WP_000821841.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| QCL60_RS23305 (77666) | 77666..78304 | - | 639 | WP_000777700.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| QCL60_RS23310 (78313) | 78313..79305 | - | 993 | WP_000830183.1 | conjugal transfer pilus assembly protein TraU | - |
| QCL60_RS23315 (79302) | 79302..79934 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| QCL60_RS23320 (79931) | 79931..80317 | - | 387 | WP_000099686.1 | type-F conjugative transfer system protein TrbI | - |
| QCL60_RS23325 (80314) | 80314..82941 | - | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| QCL60_RS23330 (83101) | 83101..83322 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| QCL60_RS23335 (83457) | 83457..83972 | - | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| QCL60_RS23340 (83969) | 83969..84220 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| QCL60_RS23345 (84232) | 84232..84429 | - | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| QCL60_RS23350 (84416) | 84416..85006 | - | 591 | WP_001376242.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| QCL60_RS23355 (84996) | 84996..86423 | - | 1428 | WP_000146685.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| QCL60_RS23360 (86423) | 86423..87151 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| QCL60_RS23365 (87138) | 87138..87704 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| QCL60_RS23370 (87726) | 87726..88037 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| QCL60_RS23375 (88052) | 88052..88417 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| QCL60_RS23380 (88450) | 88450..88851 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| QCL60_RS23385 (88944) | 88944..89633 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| QCL60_RS23390 (89820) | 89820..90203 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| QCL60_RS23395 (90536) | 90536..91126 | + | 591 | WP_001376243.1 | hypothetical protein | VF |
| QCL60_RS23400 (91423) | 91423..92244 | - | 822 | WP_001234426.1 | DUF932 domain-containing protein | - |
| QCL60_RS23405 (92362) | 92362..92649 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| QCL60_RS23410 (92674) | 92674..92880 | - | 207 | WP_000547968.1 | hypothetical protein | - |
| QCL60_RS23415 (92950) | 92950..93122 | + | 173 | Protein_104 | hypothetical protein | - |
| QCL60_RS23420 (93120) | 93120..93350 | - | 231 | WP_071586998.1 | hypothetical protein | - |
| QCL60_RS23425 (93570) | 93570..93695 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| QCL60_RS23430 (93637) | 93637..93786 | - | 150 | Protein_107 | plasmid maintenance protein Mok | - |
| - (93772) | 93772..93996 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (93772) | 93772..93996 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (93772) | 93772..93996 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (93772) | 93772..93996 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| QCL60_RS23435 (93808) | 93808..93996 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| QCL60_RS23440 (93965) | 93965..94727 | - | 763 | Protein_109 | plasmid SOS inhibition protein A | - |
| QCL60_RS23445 (94724) | 94724..95158 | - | 435 | WP_000845936.1 | conjugation system SOS inhibitor PsiB | - |
| QCL60_RS23450 (95213) | 95213..95410 | - | 198 | Protein_111 | hypothetical protein | - |
| QCL60_RS23455 (95438) | 95438..95671 | - | 234 | WP_000005987.1 | DUF905 family protein | - |
| QCL60_RS23460 (95739) | 95739..96278 | - | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| QCL60_RS23465 (96304) | 96304..96510 | - | 207 | WP_000275856.1 | hypothetical protein | - |
| QCL60_RS23470 (96580) | 96580..96660 | + | 81 | Protein_115 | hypothetical protein | - |
| QCL60_RS23475 (96843) | 96843..97012 | - | 170 | Protein_116 | hypothetical protein | - |
| QCL60_RS23480 (97649) | 97649..98620 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| QCL60_RS23485 (98620) | 98620..99786 | - | 1167 | WP_001238646.1 | hypothetical protein | VF |
| QCL60_RS23495 (101061) | 101061..103262 | - | 2202 | WP_000973520.1 | Ferric aerobactin receptor | VF |
| QCL60_RS23500 (103288) | 103288..104621 | - | 1334 | Protein_121 | L-lysine N6-monooxygenase | VF |
| QCL60_RS23505 (104618) | 104618..106360 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| QCL60_RS23510 (106360) | 106360..107307 | - | 948 | WP_000011910.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| QCL60_RS23515 (107308) | 107308..109032 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| QCL60_RS23520 (109168) | 109168..110361 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| QCL60_RS23525 (110741) | 110741..111121 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| QCL60_RS23530 (111462) | 111462..111875 | - | 414 | Protein_127 | phosphopyruvate hydratase | - |
| QCL60_RS23535 (111873) | 111873..112130 | + | 258 | Protein_128 | Tn3 family transposase | - |
| QCL60_RS23540 (112364) | 112364..113221 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| QCL60_RS23545 (113218) | 113218..114075 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| QCL60_RS23550 (114072) | 114072..114899 | - | 828 | WP_000983710.1 | Manganese transport system ATP-binding protein MntB | VF |
| QCL60_RS23555 (114899) | 114899..115813 | - | 915 | WP_000949004.1 | putative periplasmic iron-binding protein | VF |
| QCL60_RS23560 (116169) | 116169..116866 | + | 698 | WP_223155668.1 | IS1 family transposase IS1S | Transposase |
| QCL60_RS23565 (117046) | 117046..117559 | - | 514 | Protein_134 | DUF4113 domain-containing protein | - |
| QCL60_RS23570 (117620) | 117620..117724 | - | 105 | Protein_135 | AAA family ATPase | - |
| QCL60_RS23575 (117726) | 117726..118049 | - | 324 | Protein_136 | IS21 family transposase IS21 | Transposase |
| QCL60_RS23580 (118795) | 118795..119772 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| QCL60_RS23585 (120057) | 120057..120797 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| QCL60_RS23590 (120918) | 120918..121106 | - | 189 | WP_001324033.1 | hypothetical protein | - |
| QCL60_RS23595 (121480) | 121480..122382 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| QCL60_RS23600 (122451) | 122451..123560 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| QCL60_RS23605 (123993) | 123993..124946 | - | 954 | WP_000280980.1 | Protease 7 | VF |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|