MGE detailed information
MGE type: Conjugative plasmid MGE length: 93908 bp
Accession: NZ_CP121360 Location: 1..93908 Organism: Escherichia coli strain rl0044 Replicon: plasmid pVP443
Accession: NZ_CP121360 Location: 1..93908 Organism: Escherichia coli strain rl0044 Replicon: plasmid pVP443
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| P9060_RS27955 (1) | 1..978 | + | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| P9060_RS27960 (1263) | 1263..2003 | - | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| P9060_RS27965 (2366) | 2366..2660 | - | 295 | Protein_2 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| P9060_RS27970 (2647) | 2647..2897 | - | 251 | Protein_3 | type II toxin-antitoxin system ParD family antitoxin | - |
| P9060_RS27975 (3420) | 3420..3529 | - | 110 | Protein_4 | IS5/IS1182 family transposase | - |
| P9060_RS27980 (3980) | 3980..4222 | + | 243 | WP_050562259.1 | toxin-activating lysine-acyltransferase | - |
| P9060_RS27985 (4694) | 4694..4822 | + | 129 | Protein_6 | Transcriptional repressor MprA | VF |
| P9060_RS27990 (4871) | 4871..5194 | + | 324 | WP_230909587.1 | Transcriptional repressor MprA | VF |
| P9060_RS27995 (5541) | 5541..6664 | - | 1124 | Protein_8 | IS3 family transposase IS3F | Transposase |
| P9060_RS28000 (6734) | 6734..6907 | + | 174 | Protein_9 | IS3 family transposase | - |
| P9060_RS28005 (6985) | 6985..7652 | + | 668 | Protein_10 | IS3 family transposase ISKpn38 | Transposase |
| P9060_RS28010 (7680) | 7680..8443 | - | 764 | Protein_11 | IS3 family transposase IS2 | Transposase |
| P9060_RS28015 (8519) | 8519..8671 | + | 153 | Protein_12 | transposase | - |
| P9060_RS28020 (8829) | 8829..8930 | + | 102 | Protein_13 | restriction endonuclease subunit M | - |
| P9060_RS28025 (8998) | 8998..10533 | + | 1536 | WP_278242788.1 | hypothetical protein | VF |
| P9060_RS28030 (10649) | 10649..10927 | - | 279 | Protein_15 | transposase | - |
| P9060_RS28035 (10954) | 10954..12567 | - | 1614 | WP_000080195.1 | IS66 family transposase ISEc23 | Transposase |
| P9060_RS28040 (12598) | 12598..12948 | - | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| P9060_RS28045 (12945) | 12945..13370 | - | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| P9060_RS28050 (13456) | 13456..14299 | - | 844 | Protein_19 | IS3 family transposase | - |
| P9060_RS28055 (14687) | 14687..14902 | - | 216 | WP_000739296.1 | heat-stable enterotoxin ST-II | - |
| P9060_RS28060 (15379) | 15379..15958 | - | 580 | Protein_21 | IS256 family transposase | - |
| P9060_RS28065 (15984) | 15984..16283 | + | 300 | Protein_22 | IS3 family transposase | - |
| P9060_RS28070 (16474) | 16474..18051 | - | 1578 | WP_001323889.1 | Aerotaxis receptor | VF |
| P9060_RS28075 (18361) | 18361..18921 | + | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| P9060_RS28080 (18925) | 18925..21891 | + | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| P9060_RS28085 (21924) | 21924..22273 | + | 350 | Protein_26 | integrase core domain-containing protein | - |
| P9060_RS28090 (22365) | 22365..23336 | - | 972 | WP_001078349.1 | IS481 family transposase ISEc18 | Transposase |
| P9060_RS28095 (23548) | 23548..24261 | - | 714 | WP_001424997.1 | hypothetical protein | - |
| P9060_RS28100 (24650) | 24650..24854 | + | 205 | Protein_29 | IS110 family transposase | - |
| P9060_RS28105 (25128) | 25128..25904 | + | 777 | WP_042634421.1 | Heat-labile enterotoxin A chain | VF |
| P9060_RS28110 (25901) | 25901..26275 | + | 375 | WP_015675362.1 | Heat-labile enterotoxin B chain | VF |
| P9060_RS28115 (26623) | 26623..27019 | + | 397 | Protein_32 | ATP-binding protein | - |
| P9060_RS28120 (27146) | 27146..27990 | + | 845 | Protein_33 | IS3 family transposase | - |
| P9060_RS28125 (28272) | 28272..29348 | + | 1077 | WP_000907656.1 | IS110 family transposase ISEc21 | Transposase |
| P9060_RS28130 (29365) | 29365..29673 | + | 309 | Protein_35 | IS3 family transposase IS911 | Transposase |
| P9060_RS28135 (29680) | 29680..30409 | - | 730 | Protein_36 | 3'-5' exonuclease | - |
| P9060_RS28140 (30455) | 30455..30733 | - | 279 | WP_001384452.1 | type II toxin-antitoxin system toxin YacB | Toxin Detail |
| P9060_RS28145 (30733) | 30733..31002 | - | 270 | WP_000079930.1 | type II toxin-antitoxin system antitoxin YacA | Antitoxin Detail |
| P9060_RS28150 (31919) | 31919..32941 | - | 1023 | WP_000840938.1 | plasmid replication initiator RepA | - |
| P9060_RS28155 (32934) | 32934..33008 | - | 75 | WP_032319616.1 | RepA leader peptide Tap | - |
| P9060_RS28160 (33242) | 33242..33499 | - | 258 | WP_000083834.1 | replication regulatory protein RepA | - |
| P9060_RS28165 (33779) | 33779..33919 | - | 141 | WP_064717426.1 | Hok/Gef family protein | - |
| P9060_RS28170 (33979) | 33979..35147 | + | 1169 | WP_085959723.1 | IS3 family transposase ISLad1 | Transposase |
| - (35224) | 35224..35285 | + | 62 | NuclAT_1 | - | - |
| - (35224) | 35224..35285 | + | 62 | NuclAT_1 | - | - |
| - (35224) | 35224..35285 | + | 62 | NuclAT_1 | - | - |
| - (35224) | 35224..35285 | + | 62 | NuclAT_1 | - | - |
| P9060_RS28175 (35581) | 35581..35892 | + | 312 | WP_000765906.1 | hypothetical protein | - |
| P9060_RS28180 (36073) | 36073..36159 | - | 87 | Protein_45 | endonuclease | - |
| P9060_RS28185 (36403) | 36403..36618 | - | 216 | WP_032166857.1 | hypothetical protein | - |
| P9060_RS28190 (36754) | 36754..37314 | - | 561 | WP_000139309.1 | fertility inhibition protein FinO | - |
| P9060_RS28195 (37369) | 37369..38112 | - | 744 | WP_000205703.1 | conjugal transfer pilus acetylase TraX | - |
| P9060_RS28200 (38132) | 38132..43402 | - | 5271 | WP_000986925.1 | Multifunctional conjugation protein TraI | Relaxase |
| P9060_RS28205 (43402) | 43402..45600 | - | 2199 | WP_001425204.1 | type IV conjugative transfer system coupling protein TraD | - |
| P9060_RS28210 (45826) | 45826..46614 | - | 789 | WP_225882984.1 | hypothetical protein | - |
| P9060_RS28215 (46829) | 46829..47140 | + | 312 | WP_000522221.1 | heavy metal-binding domain-containing protein | - |
| P9060_RS28220 (47143) | 47143..49962 | - | 2820 | WP_001007033.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| P9060_RS28225 (49959) | 49959..51332 | - | 1374 | WP_001137358.1 | conjugal transfer pilus assembly protein TraH | - |
| P9060_RS28230 (51319) | 51319..51711 | - | 393 | WP_000126336.1 | F-type conjugal transfer protein TrbF | - |
| P9060_RS28235 (51665) | 51665..51979 | - | 315 | WP_001385158.1 | P-type conjugative transfer protein TrbJ | - |
| P9060_RS28240 (51969) | 51969..52523 | - | 555 | WP_000052621.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| P9060_RS28245 (52510) | 52510..52794 | - | 285 | WP_000624110.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| P9060_RS28250 (52913) | 52913..53260 | - | 348 | WP_001287903.1 | conjugal transfer protein TrbA | - |
| P9060_RS28255 (53276) | 53276..54019 | - | 744 | WP_001030375.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| P9060_RS28260 (54012) | 54012..54269 | - | 258 | WP_000864325.1 | conjugal transfer protein TrbE | - |
| P9060_RS28265 (54296) | 54296..56104 | - | 1809 | WP_000821839.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| P9060_RS28270 (56101) | 56101..56739 | - | 639 | WP_001104087.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| P9060_RS28275 (56767) | 56767..57219 | - | 453 | WP_001385157.1 | hypothetical protein | - |
| P9060_RS28280 (57212) | 57212..57526 | - | 315 | WP_001423717.1 | hypothetical protein | - |
| P9060_RS28285 (57537) | 57537..58000 | - | 464 | Protein_66 | ATP-binding protein | - |
| P9060_RS28290 (58026) | 58026..59018 | - | 993 | WP_000830834.1 | conjugal transfer pilus assembly protein TraU | - |
| P9060_RS28295 (59015) | 59015..59647 | - | 633 | WP_001203748.1 | type-F conjugative transfer system protein TraW | - |
| P9060_RS28300 (59644) | 59644..60051 | - | 408 | WP_278242786.1 | type-F conjugative transfer system protein TrbI | - |
| P9060_RS28305 (60026) | 60026..62653 | - | 2628 | WP_001064261.1 | type IV secretion system protein TraC | - |
| P9060_RS28310 (62813) | 62813..63034 | - | 222 | WP_001278685.1 | conjugal transfer protein TraR | - |
| P9060_RS28315 (63169) | 63169..63684 | - | 516 | WP_000809905.1 | type IV conjugative transfer system lipoprotein TraV | - |
| P9060_RS28320 (63681) | 63681..63932 | - | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
| P9060_RS28325 (63944) | 63944..64141 | - | 198 | WP_001423674.1 | conjugal transfer protein TrbD | - |
| P9060_RS28330 (64128) | 64128..64712 | - | 585 | WP_001423675.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| P9060_RS28335 (64702) | 64702..66150 | - | 1449 | WP_000146643.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| P9060_RS28340 (66150) | 66150..66878 | - | 729 | WP_001230776.1 | type-F conjugative transfer system secretin TraK | - |
| P9060_RS28345 (66865) | 66865..67431 | - | 567 | WP_064986971.1 | type IV conjugative transfer system protein TraE | - |
| P9060_RS28350 (67453) | 67453..67764 | - | 312 | WP_000012125.1 | type IV conjugative transfer system protein TraL | - |
| P9060_RS28355 (67779) | 67779..68144 | - | 366 | WP_000338819.1 | type IV conjugative transfer system pilin TraA | - |
| P9060_RS28360 (68188) | 68188..68403 | - | 216 | WP_071782156.1 | conjugal transfer relaxosome protein TraY | - |
| P9060_RS28365 (68539) | 68539..69186 | - | 648 | WP_000332521.1 | conjugal transfer transcriptional regulator TraJ | - |
| P9060_RS28370 (69377) | 69377..69760 | - | 384 | WP_001151534.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| P9060_RS28375 (70081) | 70081..70683 | + | 603 | WP_077632063.1 | hypothetical protein | VF |
| P9060_RS28380 (70979) | 70979..71800 | - | 822 | WP_001424949.1 | DUF932 domain-containing protein | - |
| P9060_RS28385 (71918) | 71918..72205 | - | 288 | WP_000107541.1 | hypothetical protein | - |
| P9060_RS28390 (72265) | 72265..72451 | + | 187 | Protein_87 | pilus protein | - |
| P9060_RS28395 (72752) | 72752..72877 | - | 126 | WP_096937776.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| P9060_RS28400 (72819) | 72819..72968 | - | 150 | Protein_89 | DUF5431 family protein | - |
| - (72975) | 72975..73173 | - | 199 | NuclAT_0 | - | - |
| - (72975) | 72975..73173 | - | 199 | NuclAT_0 | - | - |
| - (72975) | 72975..73173 | - | 199 | NuclAT_0 | - | - |
| - (72975) | 72975..73173 | - | 199 | NuclAT_0 | - | - |
| P9060_RS28405 (73142) | 73142..73904 | - | 763 | Protein_90 | plasmid SOS inhibition protein A | - |
| P9060_RS28410 (73901) | 73901..74335 | - | 435 | WP_278242787.1 | conjugation system SOS inhibitor PsiB | - |
| P9060_RS28415 (74390) | 74390..76348 | - | 1959 | WP_000117204.1 | ParB/RepB/Spo0J family partition protein | - |
| P9060_RS28420 (76412) | 76412..76645 | - | 234 | WP_000005985.1 | DUF905 family protein | - |
| P9060_RS28425 (76707) | 76707..77246 | - | 540 | WP_000290811.1 | single-stranded DNA-binding protein | - |
| P9060_RS28430 (77272) | 77272..77478 | - | 207 | WP_000275848.1 | hypothetical protein | - |
| P9060_RS28435 (77548) | 77548..77974 | + | 427 | Protein_96 | hypothetical protein | - |
| P9060_RS28440 (78060) | 78060..78623 | - | 564 | WP_001423687.1 | class I SAM-dependent methyltransferase | - |
| P9060_RS28445 (78670) | 78670..80031 | - | 1362 | WP_000170653.1 | DUF3560 domain-containing protein | - |
| P9060_RS28450 (80083) | 80083..80313 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| P9060_RS28455 (81300) | 81300..81491 | - | 192 | WP_001027495.1 | hypothetical protein | - |
| P9060_RS28460 (81491) | 81491..81910 | - | 420 | WP_000271716.1 | DUF1380 family protein | - |
| P9060_RS28465 (81957) | 81957..82382 | - | 426 | WP_001198941.1 | antirestriction protein | - |
| P9060_RS28470 (82799) | 82799..83578 | - | 780 | WP_001423681.1 | hypothetical protein | - |
| P9060_RS28475 (83629) | 83629..84063 | - | 435 | WP_000274480.1 | DUF1380 family protein | - |
| P9060_RS28480 (84077) | 84077..84298 | - | 222 | WP_001104880.1 | hypothetical protein | - |
| P9060_RS28485 (84299) | 84299..84910 | - | 612 | Protein_106 | DNA methylase | - |
| P9060_RS28490 (85532) | 85532..87232 | + | 1701 | WP_000125555.1 | group II intron reverse transcriptase/maturase | - |
| P9060_RS28495 (87314) | 87314..87385 | - | 72 | Protein_108 | hypothetical protein | - |
| P9060_RS28500 (87462) | 87462..87773 | - | 312 | WP_001309256.1 | hypothetical protein | - |
| P9060_RS28505 (87770) | 87770..88298 | - | 529 | Protein_110 | DUF1281 domain-containing protein | - |
| P9060_RS28510 (88300) | 88300..88383 | + | 84 | Protein_111 | DUF4113 domain-containing protein | - |
| P9060_RS28515 (88513) | 88513..89290 | - | 778 | Protein_112 | transposase DNA-binding-containing protein | - |
| P9060_RS28520 (89524) | 89524..90486 | - | 963 | WP_000756327.1 | ParB family protein | - |
| P9060_RS28525 (90483) | 90483..91688 | - | 1206 | WP_000817634.1 | Plasmid partition protein A | VF |
| P9060_RS28530 (92062) | 92062..92274 | + | 213 | WP_000402944.1 | hypothetical protein | - |
| P9060_RS28535 (92447) | 92447..92698 | + | 252 | WP_001132895.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| P9060_RS28540 (92695) | 92695..92982 | + | 288 | WP_001270417.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| P9060_RS28545 (92984) | 92984..93229 | + | 246 | Protein_118 | integrase core domain-containing protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|