MGE detailed information
MGE type: Conjugative plasmid MGE length: 124410 bp
Accession: NZ_CP121154 Location: 1..124410 Organism: Escherichia coli strain E57 Replicon: plasmid pE57-1
Accession: NZ_CP121154 Location: 1..124410 Organism: Escherichia coli strain E57 Replicon: plasmid pE57-1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| P6H84_RS23920 (1184) | 1184..2137 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| P6H84_RS23925 (3434) | 3434..3613 | - | 180 | Protein_2 | integrase core domain-containing protein | - |
| P6H84_RS23930 (3752) | 3752..4965 | + | 1214 | WP_162842477.1 | IS3 family transposase IS629 | Transposase |
| P6H84_RS23935 (5113) | 5113..5381 | - | 269 | Protein_4 | IS3 family transposase ISLad1 | Transposase |
| P6H84_RS23940 (5438) | 5438..6135 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| P6H84_RS23945 (6197) | 6197..6988 | - | 792 | WP_000016493.1 | site-specific integrase | - |
| P6H84_RS23950 (6985) | 6985..7674 | - | 690 | WP_000796228.1 | hypothetical protein | - |
| P6H84_RS23955 (7718) | 7718..8068 | - | 351 | WP_000493379.1 | hypothetical protein | - |
| P6H84_RS23960 (8613) | 8613..9701 | + | 1089 | WP_000952217.1 | transcriptional repressor PifC | - |
| P6H84_RS23965 (9703) | 9703..11928 | + | 2226 | WP_000698737.1 | P-loop NTPase fold protein | - |
| P6H84_RS23970 (11978) | 11978..12877 | - | 900 | WP_000963206.1 | nucleotide-binding protein | - |
| P6H84_RS23975 (12867) | 12867..13157 | - | 291 | WP_000111771.1 | hypothetical protein | - |
| P6H84_RS23980 (13453) | 13453..13683 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| P6H84_RS23985 (13680) | 13680..14096 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| P6H84_RS23990 (14258) | 14258..16396 | - | 2139 | WP_000350638.1 | AAA family ATPase | - |
| P6H84_RS23995 (16750) | 16750..17007 | + | 258 | WP_000343085.1 | hypothetical protein | - |
| P6H84_RS24000 (17007) | 17007..17597 | + | 591 | WP_000194575.1 | hypothetical protein | - |
| P6H84_RS24005 (17860) | 17860..19416 | + | 1557 | WP_000818556.1 | AAA family ATPase | - |
| P6H84_RS24010 (19608) | 19608..20225 | + | 618 | WP_000521603.1 | ProQ/FINO family protein | - |
| P6H84_RS24015 (20518) | 20518..21597 | - | 1080 | WP_001089727.1 | permease | - |
| P6H84_RS24020 (21702) | 21702..22025 | + | 324 | WP_001175594.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| P6H84_RS24025 (22186) | 22186..22506 | + | 321 | Protein_22 | NAD(P)H-dependent oxidoreductase | - |
| P6H84_RS24030 (22559) | 22559..23263 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P6H84_RS24035 (23329) | 23329..24843 | + | 1515 | Protein_24 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| P6H84_RS24040 (24901) | 24901..25143 | + | 243 | WP_000844627.1 | transposase | - |
| P6H84_RS24045 (25175) | 25175..25825 | - | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| P6H84_RS24050 (25931) | 25931..27130 | + | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| P6H84_RS24055 (27162) | 27162..28046 | - | 885 | WP_000058717.1 | EamA family transporter | - |
| P6H84_RS24060 (28184) | 28184..28576 | - | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| P6H84_RS24065 (28580) | 28580..30160 | + | 1581 | Protein_30 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| P6H84_RS24070 (30211) | 30211..30915 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P6H84_RS24075 (30972) | 30972..31079 | + | 108 | Protein_32 | IS6 family transposase | - |
| P6H84_RS24080 (31269) | 31269..32084 | - | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| P6H84_RS24085 (32235) | 32235..32939 | + | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| P6H84_RS24090 (32986) | 32986..33054 | + | 69 | Protein_35 | macrolide transporter | - |
| P6H84_RS24095 (33200) | 33200..34063 | + | 864 | WP_000612791.1 | SDR family oxidoreductase | - |
| P6H84_RS24100 (34101) | 34101..34346 | + | 246 | WP_001354008.1 | GrpB family protein | - |
| P6H84_RS24105 (34815) | 34815..35606 | + | 792 | WP_000034420.1 | Dihydropteroate synthase | ARG |
| P6H84_RS24110 (35609) | 35609..35884 | - | 276 | WP_109023896.1 | hypothetical protein | - |
| P6H84_RS24115 (35907) | 35907..36539 | + | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| P6H84_RS24120 (36786) | 36786..37118 | - | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| P6H84_RS24125 (37241) | 37241..38079 | - | 839 | Protein_42 | Streptomycin 3''-adenylyltransferase | ARG |
| P6H84_RS24130 (38172) | 38172..39431 | - | 1260 | WP_000095725.1 | chloramphenicol efflux MFS transporter CmlA1 | ARG |
| P6H84_RS24135 (39646) | 39646..40484 | - | 839 | Protein_44 | Streptomycin 3''-adenylyltransferase | ARG |
| P6H84_RS24140 (40542) | 40542..41150 | - | 609 | WP_000050382.1 | HAD family hydrolase | - |
| P6H84_RS24145 (41246) | 41246..42088 | - | 843 | WP_001456218.1 | alpha/beta fold putative hydrolase EstX | - |
| P6H84_RS24150 (42255) | 42255..43268 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| P6H84_RS24155 (43471) | 43471..43821 | + | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| P6H84_RS24160 (44020) | 44020..44724 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P6H84_RS24165 (44787) | 44787..45200 | - | 414 | Protein_50 | serine hydrolase | - |
| P6H84_RS24170 (45383) | 45383..45940 | - | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| P6H84_RS24175 (46104) | 46104..46493 | + | 390 | Protein_52 | Tn3 family transposase TnpA_Tn3 | Transposase |
| P6H84_RS24180 (46561) | 46561..47658 | - | 1098 | Protein_53 | TonB-dependent receptor | - |
| P6H84_RS24185 (47715) | 47715..48683 | - | 969 | WP_013362812.1 | IS5 family transposase IS903B | Transposase |
| P6H84_RS24190 (48718) | 48718..49593 | - | 876 | WP_032277257.1 | Beta-lactamase CTX-M-97 | ARG |
| P6H84_RS24195 (49843) | 49843..50022 | - | 180 | Protein_56 | IS1380 family transposase | - |
| P6H84_RS24200 (50087) | 50087..50791 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P6H84_RS24205 (50857) | 50857..51402 | + | 546 | Protein_58 | Tn3 family transposase TnpA_Tn3 | Transposase |
| P6H84_RS24210 (51438) | 51438..51853 | - | 416 | Protein_59 | IS1-like element IS1B family transposase | - |
| P6H84_RS24215 (52102) | 52102..52503 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| P6H84_RS24220 (52436) | 52436..52693 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| P6H84_RS24225 (52786) | 52786..53439 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| P6H84_RS24230 (54379) | 54379..55236 | - | 858 | WP_000130940.1 | incFII family plasmid replication initiator RepA | - |
| P6H84_RS24235 (55229) | 55229..55276 | - | 48 | WP_077822033.1 | hypothetical protein | - |
| P6H84_RS24240 (55267) | 55267..55503 | + | 237 | WP_223368648.1 | replication protein RepA | - |
| P6H84_RS24245 (55529) | 55529..55789 | - | 261 | WP_000083818.1 | replication regulatory protein RepA | - |
| P6H84_RS24250 (56028) | 56028..56601 | - | 574 | Protein_67 | DUF2726 domain-containing protein | - |
| P6H84_RS24255 (56639) | 56639..56848 | - | 210 | WP_001333231.1 | hemolysin expression modulator Hha | - |
| P6H84_RS24260 (56894) | 56894..57355 | - | 462 | WP_001233871.1 | thermonuclease family protein | - |
| P6H84_RS24265 (57598) | 57598..57810 | - | 213 | WP_012311405.1 | hypothetical protein | - |
| P6H84_RS24270 (57948) | 57948..58508 | - | 561 | WP_000139359.1 | fertility inhibition protein FinO | - |
| P6H84_RS24275 (58563) | 58563..59309 | - | 747 | WP_000205777.1 | conjugal transfer pilus acetylase TraX | - |
| P6H84_RS24280 (59329) | 59329..60027 | - | 699 | Protein_73 | Multifunctional conjugation protein TraI | Relaxase |
| P6H84_RS24285 (60081) | 60081..60785 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P6H84_RS24290 (60848) | 60848..61063 | + | 216 | Protein_75 | IS6 family transposase IS26 | Transposase |
| P6H84_RS24295 (61120) | 61120..61896 | - | 777 | Protein_76 | IS110 family transposase IS5075 | Transposase |
| P6H84_RS24300 (61975) | 61975..64941 | - | 2967 | WP_001138070.1 | Tn3 family transposase TnpA_ISPa38 | Transposase |
| P6H84_RS24305 (64944) | 64944..65258 | - | 315 | Protein_78 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| P6H84_RS24310 (65312) | 65312..66016 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P6H84_RS24315 (66086) | 66086..66559 | - | 474 | WP_004201280.1 | Dihydrofolate reductase type 1 | ARG |
| P6H84_RS24320 (66715) | 66715..67728 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| P6H84_RS24325 (68176) | 68176..68880 | - | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| P6H84_RS24330 (69466) | 69466..69810 | + | 345 | WP_000793307.1 | hypothetical protein | - |
| P6H84_RS24335 (69986) | 69986..70987 | - | 1002 | WP_000774874.1 | DUF4238 domain-containing protein | - |
| P6H84_RS24340 (71339) | 71339..71593 | + | 255 | WP_000343103.1 | hypothetical protein | - |
| P6H84_RS24345 (71593) | 71593..72231 | + | 639 | WP_061093065.1 | hypothetical protein | - |
| P6H84_RS24350 (72450) | 72450..73454 | - | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| P6H84_RS24355 (73533) | 73533..76499 | - | 2967 | WP_001138064.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| P6H84_RS24360 (76502) | 76502..77062 | - | 561 | WP_021532377.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| P6H84_RS24365 (77113) | 77113..77817 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P6H84_RS24370 (77939) | 77939..78844 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| P6H84_RS24375 (78841) | 78841..80079 | + | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| P6H84_RS24380 (80079) | 80079..80663 | + | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| P6H84_RS24385 (81156) | 81156..81665 | - | 510 | Protein_94 | IS6 family transposase IS6100 | Transposase |
| P6H84_RS24390 (81717) | 81717..82421 | - | 705 | WP_208789585.1 | IS6 family transposase IS26 | Transposase |
| P6H84_RS24395 (82481) | 82481..83341 | - | 861 | Protein_96 | conjugal transfer protein TraN | - |
| P6H84_RS24400 (83338) | 83338..83976 | - | 639 | WP_001104248.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| P6H84_RS24405 (84004) | 84004..84456 | - | 453 | WP_000069427.1 | hypothetical protein | - |
| P6H84_RS24410 (84486) | 84486..84947 | - | 462 | WP_000277845.1 | hypothetical protein | - |
| P6H84_RS24415 (84973) | 84973..85965 | - | 993 | WP_000830839.1 | conjugal transfer pilus assembly protein TraU | - |
| P6H84_RS24420 (85962) | 85962..86594 | - | 633 | WP_001203745.1 | type-F conjugative transfer system protein TraW | - |
| P6H84_RS24425 (86591) | 86591..86977 | - | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| P6H84_RS24430 (86974) | 86974..89601 | - | 2628 | WP_001064268.1 | type IV secretion system protein TraC | - |
| P6H84_RS24435 (89761) | 89761..89982 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| P6H84_RS24440 (90117) | 90117..90632 | - | 516 | WP_000809906.1 | type IV conjugative transfer system lipoprotein TraV | - |
| P6H84_RS24445 (90629) | 90629..90880 | - | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
| P6H84_RS24450 (90877) | 90877..91194 | - | 318 | WP_001057292.1 | conjugal transfer protein TrbD | - |
| P6H84_RS24455 (91191) | 91191..91763 | - | 573 | WP_000002780.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| P6H84_RS24460 (91753) | 91753..93180 | - | 1428 | WP_000146685.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| P6H84_RS24465 (93180) | 93180..93908 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| P6H84_RS24470 (93895) | 93895..94461 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| P6H84_RS24475 (94483) | 94483..94794 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| P6H84_RS24480 (94809) | 94809..95168 | - | 360 | WP_000340272.1 | type IV conjugative transfer system pilin TraA | - |
| P6H84_RS24485 (95202) | 95202..95429 | - | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| P6H84_RS24490 (95523) | 95523..96209 | - | 687 | WP_000332484.1 | PAS domain-containing protein | - |
| P6H84_RS24495 (96400) | 96400..96783 | - | 384 | WP_000124981.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| P6H84_RS24500 (97060) | 97060..97707 | + | 648 | WP_000614936.1 | hypothetical protein | VF |
| P6H84_RS24505 (98004) | 98004..98825 | - | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| P6H84_RS24510 (98946) | 98946..99233 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| P6H84_RS24515 (99258) | 99258..99464 | - | 207 | WP_000547939.1 | hypothetical protein | - |
| P6H84_RS24520 (99534) | 99534..99707 | + | 174 | Protein_121 | hypothetical protein | - |
| P6H84_RS24525 (99705) | 99705..99935 | - | 231 | WP_001426396.1 | hypothetical protein | - |
| P6H84_RS24530 (100155) | 100155..100280 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| P6H84_RS24535 (100222) | 100222..100371 | - | 150 | Protein_124 | plasmid maintenance protein Mok | - |
| - (100357) | 100357..100388 | - | 32 | NuclAT_1 | - | Antitoxin Detail |
| - (100357) | 100357..100388 | - | 32 | NuclAT_1 | - | Antitoxin Detail |
| - (100357) | 100357..100388 | - | 32 | NuclAT_1 | - | Antitoxin Detail |
| - (100357) | 100357..100388 | - | 32 | NuclAT_1 | - | Antitoxin Detail |
| - (101830) | 101830..102027 | - | 198 | NuclAT_0 | - | - |
| - (101830) | 101830..102027 | - | 198 | NuclAT_0 | - | - |
| - (101830) | 101830..102027 | - | 198 | NuclAT_0 | - | - |
| - (101830) | 101830..102027 | - | 198 | NuclAT_0 | - | - |
| P6H84_RS24545 (101839) | 101839..102027 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| P6H84_RS24550 (101996) | 101996..102758 | - | 763 | Protein_127 | plasmid SOS inhibition protein A | - |
| P6H84_RS24555 (102755) | 102755..103189 | - | 435 | WP_000845895.1 | conjugation system SOS inhibitor PsiB | - |
| P6H84_RS24560 (103244) | 103244..105202 | - | 1959 | WP_001145469.1 | ParB/RepB/Spo0J family partition protein | - |
| P6H84_RS24565 (105261) | 105261..105494 | - | 234 | WP_000006004.1 | DUF905 domain-containing protein | - |
| P6H84_RS24570 (105550) | 105550..106077 | - | 528 | WP_000290793.1 | single-stranded DNA-binding protein | - |
| P6H84_RS24575 (106550) | 106550..106810 | - | 261 | WP_072132736.1 | hypothetical protein | - |
| P6H84_RS24580 (106720) | 106720..106962 | - | 243 | WP_001610271.1 | hypothetical protein | - |
| P6H84_RS24585 (106962) | 106962..107525 | - | 564 | WP_001311069.1 | class I SAM-dependent methyltransferase | - |
| P6H84_RS24590 (107571) | 107571..108932 | - | 1362 | WP_000170681.1 | DUF3560 domain-containing protein | - |
| P6H84_RS24595 (108984) | 108984..109214 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| P6H84_RS24600 (109731) | 109731..109984 | + | 254 | Protein_137 | hypothetical protein | - |
| P6H84_RS24605 (110208) | 110208..110390 | - | 183 | WP_001027505.1 | hypothetical protein | - |
| P6H84_RS24610 (110390) | 110390..110851 | - | 462 | WP_042007484.1 | DUF1380 family protein | - |
| P6H84_RS24615 (110851) | 110851..111276 | - | 426 | WP_001198922.1 | antirestriction protein | - |
| P6H84_RS24620 (111678) | 111678..112649 | + | 972 | WP_000082154.1 | IS110 family transposase ISEc32 | Transposase |
| P6H84_RS24630 (113450) | 113450..113785 | - | 336 | WP_000343070.1 | hypothetical protein | - |
| P6H84_RS24635 (113854) | 113854..114201 | - | 348 | WP_001350917.1 | hypothetical protein | - |
| P6H84_RS24640 (114198) | 114198..114367 | - | 170 | Protein_145 | hypothetical protein | - |
| P6H84_RS24645 (115004) | 115004..115975 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| P6H84_RS24650 (115975) | 115975..117141 | - | 1167 | WP_001238646.1 | hypothetical protein | VF |
| P6H84_RS24660 (118195) | 118195..118389 | - | 195 | Protein_149 | IS21 family transposase IS21 | Transposase |
| P6H84_RS24665 (118638) | 118638..119851 | + | 1214 | WP_085947772.1 | IS3 family transposase ISCfr6 | Transposase |
| P6H84_RS24670 (120396) | 120396..121373 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| P6H84_RS24675 (121658) | 121658..122398 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| P6H84_RS24680 (122519) | 122519..122707 | - | 189 | WP_014640565.1 | hypothetical protein | - |
| P6H84_RS24685 (123081) | 123081..123983 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|