MGE detailed information
MGE type: Conjugative plasmid MGE length: 124410 bp
Accession: NZ_CP121148 Location: 1..124410 Organism: Escherichia coli strain E20 Replicon: plasmid pE20-1
Accession: NZ_CP121148 Location: 1..124410 Organism: Escherichia coli strain E20 Replicon: plasmid pE20-1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| P6H07_RS23745 (620) | 620..964 | + | 345 | WP_000793307.1 | hypothetical protein | - |
| P6H07_RS23750 (1140) | 1140..2141 | - | 1002 | WP_000774874.1 | DUF4238 domain-containing protein | - |
| P6H07_RS23755 (2493) | 2493..2747 | + | 255 | WP_000343103.1 | hypothetical protein | - |
| P6H07_RS23760 (2747) | 2747..3385 | + | 639 | WP_061093065.1 | hypothetical protein | - |
| P6H07_RS23765 (3604) | 3604..4608 | - | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| P6H07_RS23770 (4687) | 4687..7653 | - | 2967 | WP_001138064.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| P6H07_RS23775 (7656) | 7656..8216 | - | 561 | WP_021532377.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| P6H07_RS23780 (8267) | 8267..8971 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P6H07_RS23785 (9093) | 9093..9998 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| P6H07_RS23790 (9995) | 9995..11233 | + | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| P6H07_RS23795 (11233) | 11233..11817 | + | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| P6H07_RS23800 (12310) | 12310..12819 | - | 510 | Protein_12 | IS6 family transposase IS6100 | Transposase |
| P6H07_RS23805 (12871) | 12871..13575 | - | 705 | WP_208789585.1 | IS6 family transposase IS26 | Transposase |
| P6H07_RS23810 (13635) | 13635..14495 | - | 861 | Protein_14 | conjugal transfer protein TraN | - |
| P6H07_RS23815 (14492) | 14492..15130 | - | 639 | WP_001104248.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| P6H07_RS23820 (15158) | 15158..15610 | - | 453 | WP_000069427.1 | hypothetical protein | - |
| P6H07_RS23825 (15640) | 15640..16101 | - | 462 | WP_000277845.1 | hypothetical protein | - |
| P6H07_RS23830 (16127) | 16127..17119 | - | 993 | WP_000830839.1 | conjugal transfer pilus assembly protein TraU | - |
| P6H07_RS23835 (17116) | 17116..17748 | - | 633 | WP_001203745.1 | type-F conjugative transfer system protein TraW | - |
| P6H07_RS23840 (17745) | 17745..18131 | - | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| P6H07_RS23845 (18128) | 18128..20755 | - | 2628 | WP_001064268.1 | type IV secretion system protein TraC | - |
| P6H07_RS23850 (20915) | 20915..21136 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| P6H07_RS23855 (21271) | 21271..21786 | - | 516 | WP_000809906.1 | type IV conjugative transfer system lipoprotein TraV | - |
| P6H07_RS23860 (21783) | 21783..22034 | - | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
| P6H07_RS23865 (22031) | 22031..22348 | - | 318 | WP_001057292.1 | conjugal transfer protein TrbD | - |
| P6H07_RS23870 (22345) | 22345..22917 | - | 573 | WP_000002780.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| P6H07_RS23875 (22907) | 22907..24334 | - | 1428 | WP_000146685.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| P6H07_RS23880 (24334) | 24334..25062 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| P6H07_RS23885 (25049) | 25049..25615 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| P6H07_RS23890 (25637) | 25637..25948 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| P6H07_RS23895 (25963) | 25963..26322 | - | 360 | WP_000340272.1 | type IV conjugative transfer system pilin TraA | - |
| P6H07_RS23900 (26356) | 26356..26583 | - | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| P6H07_RS23905 (26677) | 26677..27363 | - | 687 | WP_000332484.1 | PAS domain-containing protein | - |
| P6H07_RS23910 (27554) | 27554..27937 | - | 384 | WP_000124981.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| P6H07_RS23915 (28214) | 28214..28861 | + | 648 | WP_000614936.1 | hypothetical protein | VF |
| P6H07_RS23920 (29158) | 29158..29979 | - | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| P6H07_RS23925 (30100) | 30100..30387 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| P6H07_RS23930 (30412) | 30412..30618 | - | 207 | WP_000547939.1 | hypothetical protein | - |
| P6H07_RS23935 (30688) | 30688..30861 | + | 174 | Protein_39 | hypothetical protein | - |
| P6H07_RS23940 (30859) | 30859..31089 | - | 231 | WP_001426396.1 | hypothetical protein | - |
| P6H07_RS23945 (31309) | 31309..31434 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| P6H07_RS23950 (31376) | 31376..31525 | - | 150 | Protein_42 | plasmid maintenance protein Mok | - |
| - (31511) | 31511..31542 | - | 32 | NuclAT_1 | - | Antitoxin Detail |
| - (31511) | 31511..31542 | - | 32 | NuclAT_1 | - | Antitoxin Detail |
| - (31511) | 31511..31542 | - | 32 | NuclAT_1 | - | Antitoxin Detail |
| - (31511) | 31511..31542 | - | 32 | NuclAT_1 | - | Antitoxin Detail |
| - (32984) | 32984..33181 | - | 198 | NuclAT_0 | - | - |
| - (32984) | 32984..33181 | - | 198 | NuclAT_0 | - | - |
| - (32984) | 32984..33181 | - | 198 | NuclAT_0 | - | - |
| - (32984) | 32984..33181 | - | 198 | NuclAT_0 | - | - |
| P6H07_RS23960 (32993) | 32993..33181 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| P6H07_RS23965 (33150) | 33150..33912 | - | 763 | Protein_45 | plasmid SOS inhibition protein A | - |
| P6H07_RS23970 (33909) | 33909..34343 | - | 435 | WP_000845895.1 | conjugation system SOS inhibitor PsiB | - |
| P6H07_RS23975 (34398) | 34398..36356 | - | 1959 | WP_001145469.1 | ParB/RepB/Spo0J family partition protein | - |
| P6H07_RS23980 (36415) | 36415..36648 | - | 234 | WP_000006004.1 | DUF905 domain-containing protein | - |
| P6H07_RS23985 (36704) | 36704..37231 | - | 528 | WP_000290793.1 | single-stranded DNA-binding protein | - |
| P6H07_RS23990 (37704) | 37704..37964 | - | 261 | WP_072132736.1 | hypothetical protein | - |
| P6H07_RS23995 (37874) | 37874..38116 | - | 243 | WP_001610271.1 | hypothetical protein | - |
| P6H07_RS24000 (38116) | 38116..38679 | - | 564 | WP_001311069.1 | class I SAM-dependent methyltransferase | - |
| P6H07_RS24005 (38725) | 38725..40086 | - | 1362 | WP_000170681.1 | DUF3560 domain-containing protein | - |
| P6H07_RS24010 (40138) | 40138..40368 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| P6H07_RS24015 (40885) | 40885..41138 | + | 254 | Protein_55 | hypothetical protein | - |
| P6H07_RS24020 (41362) | 41362..41544 | - | 183 | WP_001027505.1 | hypothetical protein | - |
| P6H07_RS24025 (41544) | 41544..42005 | - | 462 | WP_042007484.1 | DUF1380 family protein | - |
| P6H07_RS24030 (42005) | 42005..42430 | - | 426 | WP_001198922.1 | antirestriction protein | - |
| P6H07_RS24035 (42832) | 42832..43803 | + | 972 | WP_000082154.1 | IS110 family transposase ISEc32 | Transposase |
| P6H07_RS24045 (44604) | 44604..44939 | - | 336 | WP_000343070.1 | hypothetical protein | - |
| P6H07_RS24050 (45008) | 45008..45355 | - | 348 | WP_001350917.1 | hypothetical protein | - |
| P6H07_RS24055 (45352) | 45352..45521 | - | 170 | Protein_63 | hypothetical protein | - |
| P6H07_RS24060 (46158) | 46158..47129 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| P6H07_RS24065 (47129) | 47129..48295 | - | 1167 | WP_001238646.1 | hypothetical protein | VF |
| P6H07_RS24075 (49349) | 49349..49543 | - | 195 | Protein_67 | IS21 family transposase IS21 | Transposase |
| P6H07_RS24080 (49792) | 49792..51005 | + | 1214 | WP_085947772.1 | IS3 family transposase ISCfr6 | Transposase |
| P6H07_RS24085 (51550) | 51550..52527 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| P6H07_RS24090 (52812) | 52812..53552 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| P6H07_RS24095 (53673) | 53673..53861 | - | 189 | WP_014640565.1 | hypothetical protein | - |
| P6H07_RS24100 (54235) | 54235..55137 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| P6H07_RS24105 (55206) | 55206..56315 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| P6H07_RS24110 (56748) | 56748..57701 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| P6H07_RS24115 (58998) | 58998..59177 | - | 180 | Protein_75 | integrase core domain-containing protein | - |
| P6H07_RS24120 (59316) | 59316..60529 | + | 1214 | WP_162842477.1 | IS3 family transposase IS629 | Transposase |
| P6H07_RS24125 (60677) | 60677..60945 | - | 269 | Protein_77 | IS3 family transposase ISLad1 | Transposase |
| P6H07_RS24130 (61002) | 61002..61699 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| P6H07_RS24135 (61761) | 61761..62552 | - | 792 | WP_000016493.1 | site-specific integrase | - |
| P6H07_RS24140 (62549) | 62549..63238 | - | 690 | WP_000796228.1 | hypothetical protein | - |
| P6H07_RS24145 (63282) | 63282..63632 | - | 351 | WP_000493379.1 | hypothetical protein | - |
| P6H07_RS24150 (64177) | 64177..65265 | + | 1089 | WP_000952217.1 | transcriptional repressor PifC | - |
| P6H07_RS24155 (65267) | 65267..67492 | + | 2226 | WP_000698737.1 | P-loop NTPase fold protein | - |
| P6H07_RS24160 (67542) | 67542..68441 | - | 900 | WP_000963206.1 | nucleotide-binding protein | - |
| P6H07_RS24165 (68431) | 68431..68721 | - | 291 | WP_000111771.1 | hypothetical protein | - |
| P6H07_RS24170 (69017) | 69017..69247 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| P6H07_RS24175 (69244) | 69244..69660 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| P6H07_RS24180 (69822) | 69822..71960 | - | 2139 | WP_000350638.1 | AAA family ATPase | - |
| P6H07_RS24185 (72314) | 72314..72571 | + | 258 | WP_000343085.1 | hypothetical protein | - |
| P6H07_RS24190 (72571) | 72571..73161 | + | 591 | WP_000194575.1 | hypothetical protein | - |
| P6H07_RS24195 (73424) | 73424..74980 | + | 1557 | WP_000818556.1 | AAA family ATPase | - |
| P6H07_RS24200 (75172) | 75172..75789 | + | 618 | WP_000521603.1 | ProQ/FINO family protein | - |
| P6H07_RS24205 (76082) | 76082..77161 | - | 1080 | WP_001089727.1 | permease | - |
| P6H07_RS24210 (77266) | 77266..77589 | + | 324 | WP_001175594.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| P6H07_RS24215 (77750) | 77750..78070 | + | 321 | Protein_95 | NAD(P)H-dependent oxidoreductase | - |
| P6H07_RS24220 (78123) | 78123..78827 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P6H07_RS24225 (78893) | 78893..80407 | + | 1515 | Protein_97 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| P6H07_RS24230 (80465) | 80465..80707 | + | 243 | WP_000844627.1 | transposase | - |
| P6H07_RS24235 (80739) | 80739..81389 | - | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| P6H07_RS24240 (81495) | 81495..82694 | + | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| P6H07_RS24245 (82726) | 82726..83610 | - | 885 | WP_000058717.1 | EamA family transporter | - |
| P6H07_RS24250 (83748) | 83748..84140 | - | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| P6H07_RS24255 (84144) | 84144..85724 | + | 1581 | Protein_103 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| P6H07_RS24260 (85775) | 85775..86479 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P6H07_RS24265 (86536) | 86536..86643 | + | 108 | Protein_105 | IS6 family transposase | - |
| P6H07_RS24270 (86833) | 86833..87648 | - | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| P6H07_RS24275 (87799) | 87799..88503 | + | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| P6H07_RS24280 (88550) | 88550..88618 | + | 69 | Protein_108 | macrolide transporter | - |
| P6H07_RS24285 (88764) | 88764..89627 | + | 864 | WP_000612791.1 | SDR family oxidoreductase | - |
| P6H07_RS24290 (89665) | 89665..89910 | + | 246 | WP_001354008.1 | GrpB family protein | - |
| P6H07_RS24295 (90379) | 90379..91170 | + | 792 | WP_000034420.1 | Dihydropteroate synthase | ARG |
| P6H07_RS24300 (91173) | 91173..91448 | - | 276 | WP_109023896.1 | hypothetical protein | - |
| P6H07_RS24305 (91471) | 91471..92103 | + | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| P6H07_RS24310 (92350) | 92350..92682 | - | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| P6H07_RS24315 (92805) | 92805..93643 | - | 839 | Protein_115 | Streptomycin 3''-adenylyltransferase | ARG |
| P6H07_RS24320 (93736) | 93736..94995 | - | 1260 | WP_000095725.1 | chloramphenicol efflux MFS transporter CmlA1 | ARG |
| P6H07_RS24325 (95210) | 95210..96048 | - | 839 | Protein_117 | Streptomycin 3''-adenylyltransferase | ARG |
| P6H07_RS24330 (96106) | 96106..96714 | - | 609 | WP_000050382.1 | HAD family hydrolase | - |
| P6H07_RS24335 (96810) | 96810..97652 | - | 843 | WP_001456218.1 | alpha/beta fold putative hydrolase EstX | - |
| P6H07_RS24340 (97819) | 97819..98832 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| P6H07_RS24345 (99035) | 99035..99385 | + | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| P6H07_RS24350 (99584) | 99584..100288 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P6H07_RS24355 (100351) | 100351..100764 | - | 414 | Protein_123 | serine hydrolase | - |
| P6H07_RS24360 (100947) | 100947..101504 | - | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| P6H07_RS24365 (101668) | 101668..102057 | + | 390 | Protein_125 | Tn3 family transposase TnpA_Tn3 | Transposase |
| P6H07_RS24370 (102125) | 102125..103222 | - | 1098 | Protein_126 | TonB-dependent receptor | - |
| P6H07_RS24375 (103279) | 103279..104247 | - | 969 | WP_013362812.1 | IS5 family transposase IS903B | Transposase |
| P6H07_RS24380 (104282) | 104282..105157 | - | 876 | WP_032277257.1 | Beta-lactamase CTX-M-97 | ARG |
| P6H07_RS24385 (105407) | 105407..105586 | - | 180 | Protein_129 | IS1380 family transposase | - |
| P6H07_RS24390 (105651) | 105651..106355 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P6H07_RS24395 (106421) | 106421..106966 | + | 546 | Protein_131 | Tn3 family transposase TnpA_Tn3 | Transposase |
| P6H07_RS24400 (107002) | 107002..107417 | - | 416 | Protein_132 | IS1-like element IS1B family transposase | - |
| P6H07_RS24405 (107666) | 107666..108067 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| P6H07_RS24410 (108000) | 108000..108257 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| P6H07_RS24415 (108350) | 108350..109003 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| P6H07_RS24420 (109943) | 109943..110800 | - | 858 | WP_000130940.1 | incFII family plasmid replication initiator RepA | - |
| P6H07_RS24425 (110793) | 110793..110840 | - | 48 | WP_077822033.1 | hypothetical protein | - |
| P6H07_RS24430 (110831) | 110831..111067 | + | 237 | WP_223368648.1 | replication protein RepA | - |
| P6H07_RS24435 (111093) | 111093..111353 | - | 261 | WP_000083818.1 | replication regulatory protein RepA | - |
| P6H07_RS24440 (111592) | 111592..112165 | - | 574 | Protein_140 | DUF2726 domain-containing protein | - |
| P6H07_RS24445 (112203) | 112203..112412 | - | 210 | WP_001333231.1 | hemolysin expression modulator Hha | - |
| P6H07_RS24450 (112458) | 112458..112919 | - | 462 | WP_001233871.1 | thermonuclease family protein | - |
| P6H07_RS24455 (113162) | 113162..113374 | - | 213 | WP_012311405.1 | hypothetical protein | - |
| P6H07_RS24460 (113512) | 113512..114072 | - | 561 | WP_000139359.1 | fertility inhibition protein FinO | - |
| P6H07_RS24465 (114127) | 114127..114873 | - | 747 | WP_000205777.1 | conjugal transfer pilus acetylase TraX | - |
| P6H07_RS24470 (114893) | 114893..115591 | - | 699 | Protein_146 | Multifunctional conjugation protein TraI | Relaxase |
| P6H07_RS24475 (115645) | 115645..116349 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P6H07_RS24480 (116412) | 116412..116627 | + | 216 | Protein_148 | IS6 family transposase IS26 | Transposase |
| P6H07_RS24485 (116684) | 116684..117460 | - | 777 | Protein_149 | IS110 family transposase IS5075 | Transposase |
| P6H07_RS24490 (117539) | 117539..120505 | - | 2967 | WP_001138070.1 | Tn3 family transposase TnpA_ISPa38 | Transposase |
| P6H07_RS24495 (120508) | 120508..120822 | - | 315 | Protein_151 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| P6H07_RS24500 (120876) | 120876..121580 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P6H07_RS24505 (121650) | 121650..122123 | - | 474 | WP_004201280.1 | Dihydrofolate reductase type 1 | ARG |
| P6H07_RS24510 (122279) | 122279..123292 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|