MGE detailed information
MGE type: Conjugative plasmid MGE length: 130351 bp
Accession: NZ_CP119728 Location: 1..130351 Organism: Escherichia coli strain E16 Replicon: plasmid pE16-2
Accession: NZ_CP119728 Location: 1..130351 Organism: Escherichia coli strain E16 Replicon: plasmid pE16-2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| P1J20_RS25360 (298) | 298..1460 | + | 1163 | WP_088846059.1 | IS3 family transposase ISEc17 | Transposase |
| P1J20_RS25365 (1477) | 1477..1997 | - | 521 | Protein_2 | IS3 family transposase IS2 | Transposase |
| P1J20_RS25370 (2622) | 2622..2915 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| P1J20_RS25375 (2973) | 2973..3172 | - | 200 | Protein_4 | lysis protein | - |
| P1J20_RS25380 (3726) | 3726..4750 | + | 1025 | Protein_5 | integrase core domain-containing protein | - |
| P1J20_RS25385 (6061) | 6061..7176 | + | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| P1J20_RS25390 (7316) | 7316..10975 | + | 3660 | WP_001389363.1 | Multidrug efflux ATP-binding/permease protein | VF |
| P1J20_RS25395 (11079) | 11079..12308 | + | 1230 | WP_000933678.1 | Enterochelin esterase | VF |
| P1J20_RS25400 (12393) | 12393..13349 | + | 957 | WP_000271274.1 | hypothetical protein | VF |
| P1J20_RS25405 (13394) | 13394..15571 | - | 2178 | WP_001222186.1 | Ferric enterobactin receptor | VF |
| P1J20_RS25410 (16437) | 16437..17471 | - | 1035 | WP_001190234.1 | 3-deoxy-7-phosphoheptulonate synthase | - |
| P1J20_RS25415 (17652) | 17652..17953 | + | 302 | Protein_12 | hypothetical protein | - |
| P1J20_RS25420 (18031) | 18031..18339 | - | 309 | WP_000377483.1 | DUF6404 family protein | - |
| P1J20_RS25425 (18492) | 18492..18617 | - | 126 | Protein_14 | type II toxin-antitoxin system toxin YacB | - |
| P1J20_RS25430 (18617) | 18617..18885 | - | 269 | Protein_15 | type II toxin-antitoxin system antitoxin YacA | - |
| P1J20_RS25435 (19496) | 19496..20770 | + | 1275 | WP_000489609.1 | HlyD family secretion protein | - |
| P1J20_RS25440 (20763) | 20763..22859 | + | 2097 | WP_000184924.1 | microcin H47 export transporter peptidase/ATP-binding subunit MchF | - |
| P1J20_RS25445 (23029) | 23029..23340 | - | 312 | WP_001259758.1 | colicin V | - |
| P1J20_RS25450 (23318) | 23318..23554 | - | 237 | WP_001323890.1 | colicin V immunity protein | - |
| P1J20_RS25455 (23673) | 23673..24116 | + | 444 | WP_001323891.1 | dehydrogenase | - |
| P1J20_RS25460 (24088) | 24088..24492 | + | 405 | WP_001389361.1 | hypothetical protein | - |
| P1J20_RS25465 (24494) | 24494..24763 | + | 270 | WP_000379710.1 | SemiSWEET transporter | - |
| P1J20_RS25470 (24760) | 24760..25740 | + | 981 | WP_063099985.1 | NAD(P)-binding domain-containing protein | - |
| P1J20_RS25475 (25816) | 25816..26196 | + | 381 | WP_001171523.1 | IS66 family transposase ISEc8 | Transposase |
| P1J20_RS25480 (26193) | 26193..26540 | + | 348 | WP_000612591.1 | IS66 family transposase ISEc8 | Transposase |
| P1J20_RS25485 (26590) | 26590..27450 | + | 861 | Protein_26 | IS66 family transposase ISEc8 | Transposase |
| P1J20_RS25490 (27486) | 27486..28784 | - | 1299 | Protein_27 | Tn3 family transposase TnpA_Tn3 | Transposase |
| P1J20_RS25495 (28852) | 28852..29555 | + | 704 | Protein_28 | IS6 family transposase IS26 | Transposase |
| P1J20_RS25500 (29749) | 29749..30135 | + | 387 | WP_063102497.1 | bleomycin binding protein | - |
| P1J20_RS25505 (30455) | 30455..30847 | - | 393 | WP_000084745.1 | pyridoxamine 5'-phosphate oxidase family protein | - |
| P1J20_RS25510 (31182) | 31182..31886 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P1J20_RS25515 (32206) | 32206..33381 | + | 1176 | WP_002914189.1 | Efflux pump periplasmic linker BepF | VF |
| P1J20_RS25520 (33405) | 33405..36557 | + | 3153 | WP_000347934.1 | multidrug efflux RND transporter permease subunit OqxB3 | VF |
| P1J20_RS25525 (36627) | 36627..37106 | - | 480 | WP_000888203.1 | Rrf2 family transcriptional regulator | - |
| P1J20_RS25530 (37208) | 37208..37912 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P1J20_RS25535 (37977) | 37977..39227 | - | 1251 | Protein_36 | transposase | - |
| P1J20_RS25540 (39302) | 39302..39970 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| P1J20_RS25545 (40006) | 40006..40242 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| P1J20_RS25550 (40239) | 40239..40601 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| P1J20_RS25555 (40619) | 40619..42313 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| P1J20_RS25560 (42365) | 42365..42787 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| P1J20_RS25565 (42823) | 42823..43098 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| P1J20_RS25570 (43112) | 43112..43462 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| P1J20_RS25575 (43534) | 43534..43968 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| P1J20_RS25585 (45021) | 45021..45422 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| P1J20_RS25590 (45355) | 45355..45612 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| P1J20_RS25595 (45705) | 45705..46013 | - | 309 | WP_226116723.1 | CPBP family intramembrane metalloprotease | - |
| P1J20_RS25600 (45955) | 45955..46347 | - | 393 | WP_000616804.1 | histidine phosphatase family protein | - |
| P1J20_RS25605 (46445) | 46445..46585 | - | 141 | WP_001333237.1 | hypothetical protein | - |
| P1J20_RS25610 (47286) | 47286..48143 | - | 858 | WP_105075777.1 | incFII family plasmid replication initiator RepA | - |
| P1J20_RS25615 (48136) | 48136..48618 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| P1J20_RS25620 (48611) | 48611..48658 | - | 48 | WP_229471593.1 | hypothetical protein | - |
| P1J20_RS25625 (48649) | 48649..48900 | + | 252 | WP_223195197.1 | replication protein RepA | - |
| P1J20_RS25630 (48917) | 48917..49174 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| P1J20_RS25635 (49458) | 49458..49607 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (49651) | 49651..49712 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (49651) | 49651..49712 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (49651) | 49651..49712 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (49651) | 49651..49712 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| P1J20_RS25640 (49968) | 49968..50042 | - | 75 | Protein_57 | endonuclease | - |
| P1J20_RS25645 (50288) | 50288..50500 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| P1J20_RS25650 (50636) | 50636..51196 | - | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| P1J20_RS25655 (51299) | 51299..52159 | - | 861 | WP_000704514.1 | Quorum-quenching protein AidA | VF |
| P1J20_RS25660 (52218) | 52218..52964 | - | 747 | WP_276170845.1 | conjugal transfer pilus acetylase TraX | - |
| P1J20_RS25665 (52984) | 52984..58254 | - | 5271 | WP_000986962.1 | Multifunctional conjugation protein TraI | Relaxase |
| P1J20_RS25670 (58336) | 58336..58563 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | - |
| P1J20_RS25675 (58583) | 58583..59863 | - | 1281 | Protein_64 | type IV conjugative transfer system coupling protein TraD | - |
| P1J20_RS25680 (60116) | 60116..60847 | - | 732 | WP_023565183.1 | conjugal transfer complement resistance protein TraT | - |
| P1J20_RS25685 (60879) | 60879..61376 | - | 498 | WP_000605857.1 | entry exclusion protein | - |
| P1J20_RS25690 (61392) | 61392..64214 | - | 2823 | WP_001007018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| P1J20_RS25695 (64211) | 64211..65584 | - | 1374 | WP_001517790.1 | conjugal transfer pilus assembly protein TraH | - |
| P1J20_RS25700 (65584) | 65584..65964 | - | 381 | WP_001389370.1 | F-type conjugal transfer protein TrbF | - |
| P1J20_RS25705 (65951) | 65951..66292 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| P1J20_RS25710 (66222) | 66222..66767 | - | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| P1J20_RS25715 (66754) | 66754..67038 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| P1J20_RS25720 (67119) | 67119..67433 | + | 315 | WP_001324103.1 | hypothetical protein | - |
| P1J20_RS25725 (67435) | 67435..67782 | - | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| P1J20_RS25730 (67798) | 67798..68541 | - | 744 | WP_001030393.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| P1J20_RS25735 (68534) | 68534..68791 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| P1J20_RS25740 (68818) | 68818..70026 | - | 1209 | Protein_77 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| P1J20_RS25745 (70019) | 70019..70981 | - | 963 | WP_276170843.1 | conjugal transfer pilus assembly protein TraU | - |
| P1J20_RS25750 (70978) | 70978..71610 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| P1J20_RS25755 (71607) | 71607..71993 | - | 387 | WP_000099686.1 | type-F conjugative transfer system protein TrbI | - |
| P1J20_RS25760 (71990) | 71990..74227 | - | 2238 | Protein_81 | type IV secretion system protein TraC | - |
| P1J20_RS25765 (74258) | 74258..74512 | - | 255 | Protein_82 | conjugal transfer protein TraP | - |
| P1J20_RS25770 (74502) | 74502..75929 | - | 1428 | WP_000146685.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| P1J20_RS25775 (75929) | 75929..76657 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| P1J20_RS25780 (76644) | 76644..77210 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| P1J20_RS25785 (77232) | 77232..77543 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| P1J20_RS25790 (77558) | 77558..77923 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| P1J20_RS25795 (77956) | 77956..78357 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| P1J20_RS25800 (78450) | 78450..79139 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| P1J20_RS25805 (79326) | 79326..79709 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| P1J20_RS25810 (80030) | 80030..80632 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| P1J20_RS25815 (80929) | 80929..81750 | - | 822 | WP_001234426.1 | DUF932 domain-containing protein | - |
| P1J20_RS25820 (81868) | 81868..82155 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| P1J20_RS25825 (82180) | 82180..82386 | - | 207 | WP_000547968.1 | hypothetical protein | - |
| P1J20_RS25830 (82456) | 82456..82628 | + | 173 | Protein_95 | hypothetical protein | - |
| P1J20_RS25835 (82626) | 82626..82856 | - | 231 | WP_071586998.1 | hypothetical protein | - |
| P1J20_RS25840 (83076) | 83076..83201 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| P1J20_RS25845 (83143) | 83143..83292 | - | 150 | Protein_98 | plasmid maintenance protein Mok | - |
| - (83278) | 83278..83502 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (83278) | 83278..83502 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (83278) | 83278..83502 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (83278) | 83278..83502 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| P1J20_RS25850 (83314) | 83314..83502 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| P1J20_RS25855 (83471) | 83471..84233 | - | 763 | Protein_100 | plasmid SOS inhibition protein A | - |
| P1J20_RS25860 (84230) | 84230..84664 | - | 435 | WP_000845936.1 | conjugation system SOS inhibitor PsiB | - |
| P1J20_RS25865 (84719) | 84719..84916 | - | 198 | Protein_102 | hypothetical protein | - |
| P1J20_RS25870 (84944) | 84944..85177 | - | 234 | WP_000005987.1 | DUF905 family protein | - |
| P1J20_RS25875 (85245) | 85245..85784 | - | 540 | WP_276170844.1 | single-stranded DNA-binding protein | - |
| P1J20_RS25880 (85810) | 85810..86016 | - | 207 | WP_000275856.1 | hypothetical protein | - |
| P1J20_RS25885 (86086) | 86086..86166 | + | 81 | Protein_106 | hypothetical protein | - |
| P1J20_RS25890 (86349) | 86349..86518 | - | 170 | Protein_107 | hypothetical protein | - |
| P1J20_RS25895 (87155) | 87155..88126 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| P1J20_RS25900 (88126) | 88126..89292 | - | 1167 | WP_001238646.1 | hypothetical protein | VF |
| P1J20_RS25910 (90774) | 90774..92975 | - | 2202 | WP_000973520.1 | Ferric aerobactin receptor | VF |
| P1J20_RS25915 (93001) | 93001..94334 | - | 1334 | Protein_112 | L-lysine N6-monooxygenase | VF |
| P1J20_RS25920 (94331) | 94331..96073 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| P1J20_RS25925 (96073) | 96073..97020 | - | 948 | WP_000011910.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| P1J20_RS25930 (97021) | 97021..98745 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| P1J20_RS25935 (98881) | 98881..100074 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| P1J20_RS25940 (100454) | 100454..100834 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| P1J20_RS25945 (101175) | 101175..101588 | - | 414 | Protein_118 | phosphopyruvate hydratase | - |
| P1J20_RS25950 (101586) | 101586..101843 | + | 258 | Protein_119 | Tn3 family transposase | - |
| P1J20_RS25955 (102077) | 102077..102934 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| P1J20_RS25960 (102931) | 102931..103788 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| P1J20_RS25965 (103785) | 103785..104612 | - | 828 | WP_000983710.1 | Manganese transport system ATP-binding protein MntB | VF |
| P1J20_RS25970 (104612) | 104612..105526 | - | 915 | WP_000949004.1 | putative periplasmic iron-binding protein | VF |
| P1J20_RS25975 (105882) | 105882..106579 | + | 698 | WP_223155668.1 | IS1 family transposase IS1S | Transposase |
| P1J20_RS25980 (106759) | 106759..107272 | - | 514 | Protein_125 | DUF4113 domain-containing protein | - |
| P1J20_RS25985 (107333) | 107333..107437 | - | 105 | Protein_126 | AAA family ATPase | - |
| P1J20_RS25990 (107439) | 107439..107762 | - | 324 | Protein_127 | IS21 family transposase IS21 | Transposase |
| P1J20_RS25995 (108508) | 108508..109485 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| P1J20_RS26000 (109770) | 109770..110510 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| P1J20_RS26005 (110631) | 110631..110819 | - | 189 | WP_001324033.1 | hypothetical protein | - |
| P1J20_RS26010 (111193) | 111193..112095 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| P1J20_RS26015 (112164) | 112164..113273 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| P1J20_RS26020 (113706) | 113706..114659 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| P1J20_RS26025 (115956) | 115956..116135 | - | 180 | Protein_134 | integrase core domain-containing protein | - |
| P1J20_RS26030 (116274) | 116274..117473 | + | 1200 | Protein_135 | IS3 family transposase IS629 | Transposase |
| P1J20_RS26035 (117621) | 117621..117946 | - | 326 | Protein_136 | IS3 family transposase ISLad1 | Transposase |
| P1J20_RS26040 (117992) | 117992..118332 | + | 341 | Protein_137 | IS3 family transposase | - |
| P1J20_RS26045 (118927) | 118927..120114 | + | 1188 | WP_000928804.1 | efflux RND transporter periplasmic adaptor subunit | - |
| P1J20_RS26050 (120111) | 120111..122051 | + | 1941 | WP_000733250.1 | Macrolide export ATP-binding/permease protein MacB | VF |
| P1J20_RS26055 (122055) | 122055..123425 | + | 1371 | WP_001312828.1 | efflux transporter outer membrane subunit | - |
| P1J20_RS26060 (123899) | 123899..124093 | + | 195 | Protein_141 | IS200/IS605-like element IS200C family transposase | - |
| P1J20_RS26065 (124222) | 124222..125163 | - | 942 | WP_000974762.1 | hypothetical protein | - |
| P1J20_RS26070 (125398) | 125398..126787 | - | 1390 | Protein_143 | ISNCY family transposase ISKpn21 | Transposase |
| P1J20_RS26075 (127097) | 127097..127246 | - | 150 | Protein_144 | IS3 family transposase IS2 | Transposase |
| P1J20_RS26080 (127424) | 127424..128617 | - | 1194 | WP_000450494.1 | GTP-binding protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|