MGE detailed information
MGE type: Conjugative plasmid MGE length: 76420 bp
Accession: NZ_CP118757 Location: 1..76420 Organism: Enterococcus faecalis strain W5 Replicon: plasmid pW5-2
Accession: NZ_CP118757 Location: 1..76420 Organism: Enterococcus faecalis strain W5 Replicon: plasmid pW5-2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PWA41_RS14255 (PWA41_14250) | 1..1011 | + | 1011 | WP_002367743.1 | replication initiator protein A | - |
| PWA41_RS14260 (PWA41_14255) | 1142..1810 | + | 669 | WP_002362416.1 | type II CAAX endopeptidase family protein | - |
| PWA41_RS14265 (PWA41_14260) | 1853..3479 | + | 1627 | Protein_2 | peptide ABC transporter substrate-binding protein | - |
| PWA41_RS14270 (PWA41_14265) | 3657..3779 | + | 123 | WP_002415665.1 | hypothetical protein | - |
| PWA41_RS14275 (PWA41_14270) | 3779..4336 | + | 558 | WP_002362413.1 | hypothetical protein | - |
| PWA41_RS14280 (PWA41_14275) | 4257..5519 | - | 1263 | WP_000119405.1 | hypothetical protein | Relaxase |
| PWA41_RS14285 (PWA41_14280) | 6083..7459 | - | 1377 | WP_001574277.1 | tetracycline efflux MFS transporter Tet(L) | ARG |
| PWA41_RS14290 (PWA41_14285) | 7653..9572 | - | 1920 | WP_001574275.1 | tetracycline resistance ribosomal protection protein Tet(M) | VF |
| PWA41_RS14295 (PWA41_14290) | 9588..9704 | - | 117 | WP_001791010.1 | tetracycline resistance determinant leader peptide | - |
| PWA41_RS14300 (PWA41_14295) | 9949..10881 | - | 933 | WP_001224319.1 | conjugal transfer protein | - |
| PWA41_RS14305 (PWA41_14300) | 10878..11879 | - | 1002 | WP_001574272.1 | hypothetical protein | VF |
| PWA41_RS14310 (PWA41_14305) | 11876..14053 | - | 2178 | WP_001574271.1 | YtxH domain-containing protein | - |
| PWA41_RS14315 (PWA41_14310) | 14056..16503 | - | 2448 | WP_000331160.1 | ATP-binding protein | - |
| PWA41_RS14320 (PWA41_14315) | 16487..16879 | - | 393 | Protein_13 | conjugal transfer protein | - |
| PWA41_RS14325 (PWA41_14320) | 16968..17465 | - | 498 | WP_000342539.1 | antirestriction protein ArdA | - |
| PWA41_RS14330 (PWA41_14325) | 17582..17803 | - | 222 | WP_001009056.1 | hypothetical protein | - |
| PWA41_RS14335 (PWA41_14330) | 17846..19051 | - | 1206 | WP_000398284.1 | hypothetical protein | Relaxase |
| PWA41_RS14340 (PWA41_14335) | 19074..19226 | - | 153 | WP_000879507.1 | - | oriT |
| PWA41_RS14345 (PWA41_14340) | 19229..20614 | - | 1386 | WP_000813488.1 | FtsK/SpoIIIE domain-containing protein | - |
| PWA41_RS14350 (PWA41_14345) | 20643..21029 | - | 387 | WP_000985015.1 | YdcP family protein | - |
| PWA41_RS14355 (PWA41_14350) | 21045..21359 | - | 315 | WP_000420682.1 | YdcP family protein | - |
| PWA41_RS14360 (PWA41_14355) | 21701..21886 | + | 186 | Protein_21 | type IV secretory system conjugative DNA transfer family protein | - |
| PWA41_RS14365 (PWA41_14360) | 21936..24095 | + | 2160 | WP_083578803.1 | ArdC-like ssDNA-binding domain-containing protein | - |
| PWA41_RS14370 (PWA41_14365) | 24128..24400 | + | 273 | WP_002362409.1 | LtrD | - |
| PWA41_RS14375 (PWA41_14370) | 24646..25002 | + | 357 | WP_002367696.1 | hypothetical protein | Relaxase |
| PWA41_RS14380 (PWA41_14375) | 25003..26687 | + | 1685 | Protein_25 | hypothetical protein | Relaxase |
| PWA41_RS14385 (PWA41_14380) | 26720..27070 | + | 351 | WP_002367698.1 | hypothetical protein | - |
| PWA41_RS14390 (PWA41_14385) | 27587..28009 | - | 423 | WP_002397492.1 | PcfJ domain-containing protein | - |
| PWA41_RS14395 (PWA41_14390) | 28161..28370 | + | 210 | WP_002397493.1 | hypothetical protein | - |
| PWA41_RS14400 (PWA41_14395) | 28337..28450 | + | 114 | Protein_29 | thermonuclease family protein | - |
| PWA41_RS14405 (PWA41_14400) | 28505..29185 | - | 681 | WP_013646119.1 | IS6 family transposase IS1216E | Transposase |
| PWA41_RS14410 (PWA41_14405) | 29513..29950 | - | 438 | WP_174116110.1 | hypothetical protein | - |
| PWA41_RS14415 (PWA41_14410) | 30078..30203 | - | 126 | Protein_32 | JAB domain-containing protein | - |
| PWA41_RS14420 (PWA41_14415) | 30657..30800 | + | 144 | WP_002360221.1 | hypothetical protein | - |
| PWA41_RS14425 (PWA41_14420) | 31055..32482 | + | 1428 | WP_065813868.1 | chloramphenicol/florfenicol efflux MFS transporter FexA | ARG |
| PWA41_RS14430 (PWA41_14425) | 32668..32838 | + | 171 | WP_105461295.1 | AraC family transcriptional regulator | - |
| PWA41_RS14435 (PWA41_14430) | 33170..35137 | + | 1968 | WP_105108188.1 | ABC-F type ribosomal protection protein OptrA | ARG |
| PWA41_RS14440 (PWA41_14435) | 35401..35535 | + | 135 | WP_002415371.1 | hypothetical protein | - |
| PWA41_RS14445 (PWA41_14440) | 36067..36429 | + | 363 | WP_024378353.1 | EFR1 family ferrodoxin | - |
| PWA41_RS14450 (PWA41_14445) | 36554..37285 | - | 732 | WP_002360844.1 | rRNA adenine N-6-methyltransferase | ARG |
| PWA41_RS14455 (PWA41_14450) | 37545..38225 | + | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| PWA41_RS14460 (PWA41_14455) | 38258..39193 | - | 936 | Protein_41 | RepB family plasmid replication initiator protein | - |
| PWA41_RS14465 (PWA41_14460) | 39558..40100 | - | 543 | WP_128713129.1 | Fic family protein | - |
| PWA41_RS14470 (PWA41_14465) | 40273..40863 | - | 591 | WP_128713128.1 | site-specific integrase | - |
| PWA41_RS14475 (PWA41_14470) | 40881..41705 | - | 825 | WP_225621064.1 | GIY-YIG nuclease family protein | - |
| PWA41_RS14480 (PWA41_14475) | 41970..42650 | - | 681 | WP_013646119.1 | IS6 family transposase IS1216E | Transposase |
| PWA41_RS14485 (PWA41_14480) | 42838..43230 | - | 393 | WP_000084745.1 | pyridoxamine 5'-phosphate oxidase family protein | - |
| PWA41_RS14490 (PWA41_14485) | 43482..43613 | - | 132 | Protein_47 | IS1380 family transposase | - |
| PWA41_RS14495 (PWA41_14490) | 43688..44368 | + | 681 | WP_161978276.1 | IS6 family transposase ISEnfa1 | Transposase |
| PWA41_RS14500 (PWA41_14495) | 44565..45395 | - | 831 | WP_128713131.1 | undecaprenyl-diphosphate phosphatase | - |
| PWA41_RS14505 (PWA41_14500) | 45395..46144 | - | 750 | WP_000933358.1 | ABC transporter permease | - |
| PWA41_RS14510 (PWA41_14505) | 46137..47054 | - | 918 | WP_104765562.1 | ATP-binding cassette domain-containing protein | - |
| PWA41_RS14515 (PWA41_14510) | 47237..47851 | - | 615 | WP_000395511.1 | bacitracin resistance transcriptional activator BcrR | - |
| PWA41_RS14520 (PWA41_14515) | 47841..48167 | - | 327 | WP_002387760.1 | DNA-binding protein | - |
| PWA41_RS14525 (PWA41_14520) | 48204..48368 | + | 165 | WP_001808810.1 | helix-turn-helix transcriptional regulator | - |
| PWA41_RS14530 (PWA41_14525) | 48407..49087 | + | 681 | WP_000191454.1 | IS6 family transposase ISEnfa1 | Transposase |
| PWA41_RS14535 (PWA41_14530) | 49095..49520 | - | 426 | WP_248299218.1 | hypothetical protein | - |
| PWA41_RS14540 (PWA41_14535) | 49924..51207 | - | 1284 | Protein_57 | hypothetical protein | - |
| PWA41_RS14550 (PWA41_14545) | 52608..53210 | - | 603 | WP_002362434.1 | Fic family protein | - |
| PWA41_RS14555 (PWA41_14550) | 53454..54632 | - | 1179 | WP_000997695.1 | IS256 family transposase ISEf1 | Transposase |
| PWA41_RS14560 (PWA41_14555) | 54821..55759 | - | 939 | WP_002362433.1 | hypothetical protein | - |
| PWA41_RS14565 (PWA41_14560) | 55871..56212 | - | 342 | WP_002362432.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin Detail |
| PWA41_RS14570 (PWA41_14565) | 56212..56442 | - | 231 | WP_002362431.1 | hypothetical protein | Antitoxin Detail |
| PWA41_RS14575 (PWA41_14570) | 56646..57266 | + | 621 | WP_002367784.1 | Tn3 family transposase TnpR_ISAli20 | Transposase |
| PWA41_RS14580 (PWA41_14575) | 57256..57570 | + | 315 | WP_002367785.1 | hypothetical protein | - |
| PWA41_RS14585 (PWA41_14580) | 57564..57770 | + | 207 | WP_002367786.1 | hypothetical protein | - |
| PWA41_RS14590 (PWA41_14585) | 57930..58124 | + | 195 | WP_002367787.1 | hypothetical protein | - |
| PWA41_RS14595 (PWA41_14590) | 58136..58327 | + | 192 | WP_002367788.1 | hypothetical protein | - |
| PWA41_RS14600 (PWA41_14595) | 58497..58712 | + | 216 | WP_002367791.1 | leucocin A/sakacin P family class II bacteriocin | - |
| PWA41_RS14605 (PWA41_14600) | 58713..59054 | + | 342 | WP_002367792.1 | bacteriocin immunity protein | - |
| PWA41_RS14610 (PWA41_14605) | 59470..59988 | + | 519 | WP_002367793.1 | hypothetical protein | - |
| PWA41_RS14615 (PWA41_14610) | 59936..60151 | + | 216 | WP_002415356.1 | hypothetical protein | - |
| PWA41_RS14620 (PWA41_14615) | 60243..60329 | + | 87 | WP_012881081.1 | type I toxin-antitoxin system Fst family toxin | - |
| PWA41_RS14625 (PWA41_14620) | 60586..60882 | + | 297 | WP_002367795.1 | hypothetical protein | - |
| PWA41_RS14630 (PWA41_14625) | 61017..61649 | + | 633 | WP_002367796.1 | AbiV family abortive infection protein | - |
| PWA41_RS14635 (PWA41_14630) | 62478..63215 | - | 738 | WP_001038795.1 | rRNA adenine N-6-methyltransferase | ARG |
| PWA41_RS14640 (PWA41_14635) | 63340..63423 | - | 84 | WP_001814874.1 | 23S rRNA methyltransferase attenuation leader peptide | - |
| PWA41_RS14645 (PWA41_14640) | 63965..64759 | - | 795 | WP_001096887.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| PWA41_RS14650 (PWA41_14645) | 64852..65394 | - | 543 | WP_000627290.1 | streptothricin N-acetyltransferase Sat4 | - |
| PWA41_RS14655 (PWA41_14650) | 65391..66299 | - | 909 | WP_001255866.1 | Aminoglycoside 6-adenylyltransferase | ARG |
| PWA41_RS14660 (PWA41_14655) | 66318..66434 | - | 117 | Protein_81 | topoisomerase DNA-binding C4 zinc finger domain-containing protein | - |
| PWA41_RS14665 (PWA41_14660) | 66604..67341 | - | 738 | WP_001038796.1 | rRNA adenine N-6-methyltransferase | ARG |
| PWA41_RS14670 (PWA41_14665) | 67466..67549 | - | 84 | WP_001814874.1 | 23S rRNA methyltransferase attenuation leader peptide | - |
| PWA41_RS14675 (PWA41_14670) | 67672..67839 | - | 168 | Protein_84 | peptide-binding protein | - |
| PWA41_RS14680 (PWA41_14675) | 67973..68122 | - | 150 | Protein_85 | topoisomerase | - |
| PWA41_RS14685 (PWA41_14680) | 68198..68878 | + | 681 | WP_010710189.1 | IS6 family transposase IS1216E | Transposase |
| PWA41_RS14690 (PWA41_14685) | 68912..69418 | - | 507 | WP_002415429.1 | IS1595 family transposase ISSsu9 | ARG |
| PWA41_RS14695 (PWA41_14690) | 69715..70032 | - | 318 | WP_002326830.1 | hypothetical protein | - |
| PWA41_RS14700 (PWA41_14695) | 70472..71335 | - | 864 | WP_002332783.1 | zeta toxin family protein | Toxin Detail |
| PWA41_RS14705 (PWA41_14700) | 71337..71609 | - | 273 | WP_002326825.1 | antitoxin | Antitoxin Detail |
| PWA41_RS14710 (PWA41_14705) | 71627..71842 | - | 216 | WP_001835296.1 | peptide-binding protein | - |
| PWA41_RS14715 (PWA41_14710) | 71934..72830 | - | 897 | WP_002326827.1 | ParA family protein | - |
| PWA41_RS14720 (PWA41_14715) | 72933..73193 | - | 261 | Protein_93 | topoisomerase DNA-binding C4 zinc finger domain-containing protein | - |
| PWA41_RS14725 (PWA41_14720) | 73363..74100 | - | 738 | WP_001038795.1 | rRNA adenine N-6-methyltransferase | ARG |
| PWA41_RS14730 (PWA41_14725) | 74225..74308 | - | 84 | WP_001814874.1 | 23S rRNA methyltransferase attenuation leader peptide | - |
| PWA41_RS14735 (PWA41_14730) | 74740..75111 | - | 372 | WP_002358205.1 | hypothetical protein | - |
| PWA41_RS14740 (PWA41_14735) | 75104..75949 | - | 846 | WP_000239313.1 | AAA family ATPase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|