MGE detailed information
MGE type: Conjugative plasmid MGE length: 145194 bp
Accession: NZ_CP118603 Location: 1..145194 Organism: Escherichia coli strain NB4833 Replicon: plasmid pNB4833-MCR
Accession: NZ_CP118603 Location: 1..145194 Organism: Escherichia coli strain NB4833 Replicon: plasmid pNB4833-MCR
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OU688_RS24795 (1) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| OU688_RS24800 (1263) | 1263..2003 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| OU688_RS24805 (2124) | 2124..2312 | - | 189 | WP_014640565.1 | hypothetical protein | - |
| OU688_RS24810 (2686) | 2686..3588 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| OU688_RS24815 (3657) | 3657..4766 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| OU688_RS24820 (5199) | 5199..6152 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| OU688_RS24825 (7449) | 7449..7628 | - | 180 | Protein_6 | integrase core domain-containing protein | - |
| OU688_RS24830 (7767) | 7767..8057 | + | 291 | Protein_7 | IS3 family transposase IS1203 | Transposase |
| OU688_RS24835 (8125) | 8125..8822 | + | 698 | WP_103215986.1 | IS1-like element IS1A family transposase | - |
| OU688_RS24840 (8816) | 8816..9097 | - | 282 | WP_072834405.1 | hypothetical protein | - |
| OU688_RS24845 (9238) | 9238..11064 | - | 1827 | WP_001339650.1 | AAA family ATPase | - |
| OU688_RS24850 (11067) | 11067..11552 | - | 486 | WP_001015823.1 | hypothetical protein | - |
| OU688_RS24855 (11542) | 11542..12642 | - | 1101 | WP_072714138.1 | hypothetical protein | - |
| OU688_RS24860 (13172) | 13172..13321 | - | 150 | Protein_13 | IS3 family transposase IS2 | Transposase |
| OU688_RS24865 (13499) | 13499..14692 | - | 1194 | WP_000450494.1 | GTP-binding protein | - |
| OU688_RS24870 (15915) | 15915..17151 | - | 1237 | Protein_15 | IS3 family transposase IS2 | Transposase |
| OU688_RS24875 (17778) | 17778..18071 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| OU688_RS24880 (18129) | 18129..18328 | - | 200 | Protein_17 | lysis protein | - |
| OU688_RS24885 (18882) | 18882..19906 | + | 1025 | Protein_18 | integrase core domain-containing protein | - |
| OU688_RS24890 (21217) | 21217..22332 | + | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| OU688_RS24895 (22472) | 22472..26131 | + | 3660 | WP_001111199.1 | Multidrug efflux ATP-binding/permease protein | VF |
| OU688_RS24900 (26235) | 26235..27464 | + | 1230 | WP_001552738.1 | Enterochelin esterase | VF |
| OU688_RS24905 (27549) | 27549..28505 | + | 957 | WP_000271276.1 | hypothetical protein | VF |
| OU688_RS24910 (28550) | 28550..30727 | - | 2178 | WP_072657522.1 | Ferric enterobactin receptor | VF |
| OU688_RS24915 (31582) | 31582..31716 | - | 135 | WP_249531455.1 | hypothetical protein | - |
| OU688_RS24925 (32492) | 32492..32566 | - | 75 | Protein_26 | colicin | - |
| OU688_RS24930 (32544) | 32544..32780 | - | 237 | WP_014640552.1 | colicin V immunity protein | - |
| OU688_RS24935 (33322) | 33322..33525 | - | 204 | Protein_28 | hypothetical protein | - |
| OU688_RS24940 (33698) | 33698..33865 | + | 168 | Protein_29 | colicin-B | - |
| OU688_RS24945 (33883) | 33883..34410 | - | 528 | WP_000203272.1 | colicin B immunity protein | - |
| OU688_RS24950 (34654) | 34654..35469 | + | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| OU688_RS24955 (35519) | 35519..35872 | - | 354 | WP_000864812.1 | colicin M immunity protein | - |
| OU688_RS24960 (36050) | 36050..36841 | - | 792 | WP_000016493.1 | site-specific integrase | - |
| OU688_RS24965 (36838) | 36838..37527 | - | 690 | WP_000796228.1 | hypothetical protein | - |
| OU688_RS24970 (37571) | 37571..37921 | - | 351 | WP_000493378.1 | hypothetical protein | - |
| OU688_RS24975 (38490) | 38490..38750 | + | 261 | WP_000343102.1 | hypothetical protein | - |
| OU688_RS24980 (38747) | 38747..39337 | + | 591 | WP_000194555.1 | hypothetical protein | - |
| OU688_RS24985 (39355) | 39355..39702 | - | 348 | WP_000142424.1 | DUF6404 family protein | - |
| OU688_RS24990 (39821) | 39821..40168 | + | 348 | WP_000762580.1 | colicin E1 family microcin immunity protein | - |
| OU688_RS24995 (40186) | 40186..42066 | - | 1881 | WP_001283356.1 | colicin Ia central receptor-binding domain-containing protein | - |
| OU688_RS25000 (42345) | 42345..43691 | - | 1347 | WP_001132019.1 | protein YagA | - |
| OU688_RS25005 (44045) | 44045..44647 | + | 603 | WP_000517689.1 | ProQ/FINO family protein | - |
| OU688_RS25010 (44703) | 44703..45197 | + | 495 | WP_001442119.1 | hypothetical protein | - |
| OU688_RS25015 (45197) | 45197..45463 | + | 267 | WP_000627831.1 | hypothetical protein | - |
| OU688_RS25020 (45940) | 45940..46431 | - | 492 | WP_000068661.1 | hypothetical protein | - |
| OU688_RS25025 (46365) | 46365..49331 | - | 2967 | WP_001138064.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| OU688_RS25030 (49334) | 49334..49744 | - | 411 | Protein_47 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| OU688_RS25035 (49808) | 49808..50512 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| OU688_RS25040 (50564) | 50564..50722 | - | 159 | Protein_49 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| OU688_RS25045 (50848) | 50848..51198 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| OU688_RS25050 (51401) | 51401..52414 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| OU688_RS25055 (52572) | 52572..53045 | + | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| OU688_RS25060 (53176) | 53176..53964 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| OU688_RS25065 (54170) | 54170..54517 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| OU688_RS25070 (54511) | 54511..55350 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| OU688_RS25075 (55755) | 55755..57296 | + | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| OU688_RS25080 (57609) | 57609..57983 | + | 375 | Protein_57 | protein-disulfide reductase DsbD family protein | - |
| OU688_RS25085 (58083) | 58083..58640 | + | 558 | Protein_58 | twin-arginine translocation (TAT) pathway signal sequence domain protein | - |
| OU688_RS25090 (58651) | 58651..59289 | - | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| OU688_RS25095 (59294) | 59294..59659 | - | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| OU688_RS25100 (59663) | 59663..60475 | - | 813 | WP_063860856.1 | Metallo-beta-lactamase type 2 | ARG |
| OU688_RS25105 (60739) | 60739..60927 | + | 189 | WP_000957857.1 | hypothetical protein | - |
| OU688_RS25110 (60937) | 60937..62136 | + | 1200 | WP_000948429.1 | IS91 family transposase ISSbo1 | Transposase |
| OU688_RS25115 (62520) | 62520..65525 | + | 3006 | WP_001143760.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| OU688_RS25120 (65692) | 65692..66282 | + | 591 | WP_000194568.1 | hypothetical protein | - |
| OU688_RS25125 (66547) | 66547..68103 | + | 1557 | WP_001579759.1 | AAA family ATPase | - |
| OU688_RS25130 (68298) | 68298..68915 | + | 618 | WP_000521604.1 | ProQ/FINO family protein | - |
| OU688_RS25135 (68974) | 68974..69966 | - | 993 | WP_001579760.1 | hypothetical protein | - |
| OU688_RS25140 (70882) | 70882..71739 | - | 858 | WP_032495102.1 | incFII family plasmid replication initiator RepA | - |
| OU688_RS25145 (71732) | 71732..71806 | - | 75 | WP_001375168.1 | RepA leader peptide Tap | - |
| OU688_RS25150 (72051) | 72051..72299 | - | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
| OU688_RS25155 (72583) | 72583..72732 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (72777) | 72777..72836 | + | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (72777) | 72777..72836 | + | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (72777) | 72777..72836 | + | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (72777) | 72777..72836 | + | 60 | NuclAT_1 | - | Antitoxin Detail |
| OU688_RS25160 (73037) | 73037..73369 | - | 333 | WP_152916585.1 | hypothetical protein | - |
| OU688_RS25165 (73431) | 73431..74030 | - | 600 | WP_032083981.1 | PIN domain-containing protein | - |
| OU688_RS25170 (74416) | 74416..74616 | - | 201 | WP_015059022.1 | hypothetical protein | - |
| OU688_RS25175 (74748) | 74748..75308 | - | 561 | WP_000139328.1 | fertility inhibition protein FinO | - |
| OU688_RS25180 (75363) | 75363..76109 | - | 747 | WP_000205770.1 | conjugal transfer pilus acetylase TraX | - |
| OU688_RS25185 (76129) | 76129..81399 | - | 5271 | WP_228194073.1 | Multifunctional conjugation protein TraI | Relaxase |
| OU688_RS25190 (81399) | 81399..83615 | - | 2217 | WP_059274178.1 | type IV conjugative transfer system coupling protein TraD | - |
| OU688_RS25195 (83666) | 83666..84403 | - | 738 | WP_015059020.1 | hypothetical protein | - |
| OU688_RS25200 (84606) | 84606..85337 | - | 732 | WP_021559024.1 | conjugal transfer complement resistance protein TraT | - |
| OU688_RS25205 (85362) | 85362..85883 | - | 522 | WP_000632668.1 | conjugal transfer entry exclusion protein TraS | - |
| OU688_RS25210 (85916) | 85916..88732 | - | 2817 | WP_015059018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| OU688_RS25215 (88729) | 88729..90102 | - | 1374 | WP_000944325.1 | conjugal transfer pilus assembly protein TraH | - |
| OU688_RS25220 (90089) | 90089..90481 | - | 393 | WP_000126338.1 | F-type conjugal transfer protein TrbF | - |
| OU688_RS25225 (90435) | 90435..90749 | - | 315 | WP_001384255.1 | P-type conjugative transfer protein TrbJ | - |
| OU688_RS25230 (90739) | 90739..91284 | - | 546 | WP_000059817.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| OU688_RS25235 (91271) | 91271..91507 | - | 237 | WP_000270010.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| OU688_RS25240 (91668) | 91668..92411 | - | 744 | WP_228194074.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| OU688_RS25245 (92404) | 92404..92661 | - | 258 | WP_053913405.1 | conjugal transfer protein TrbE | - |
| OU688_RS25250 (92688) | 92688..94538 | - | 1851 | WP_015059015.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| OU688_RS25255 (94535) | 94535..94957 | - | 423 | WP_001229309.1 | HNH endonuclease signature motif containing protein | - |
| OU688_RS25260 (94983) | 94983..95354 | - | 372 | WP_000056336.1 | hypothetical protein | - |
| OU688_RS25265 (95351) | 95351..95989 | - | 639 | WP_000087532.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| OU688_RS25270 (96016) | 96016..96537 | - | 522 | WP_015059014.1 | hypothetical protein | - |
| OU688_RS25275 (96600) | 96600..96908 | - | 309 | WP_000412447.1 | hypothetical protein | - |
| OU688_RS25280 (96935) | 96935..97927 | - | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| OU688_RS25285 (97924) | 97924..98556 | - | 633 | WP_001203735.1 | type-F conjugative transfer system protein TraW | - |
| OU688_RS25290 (98553) | 98553..98939 | - | 387 | WP_015059013.1 | type-F conjugative transfer system protein TrbI | - |
| OU688_RS25295 (98936) | 98936..101563 | - | 2628 | WP_015059012.1 | type IV secretion system protein TraC | - |
| OU688_RS25300 (101723) | 101723..101944 | - | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| OU688_RS25305 (102079) | 102079..102594 | - | 516 | WP_000809902.1 | type IV conjugative transfer system lipoprotein TraV | - |
| OU688_RS25310 (102591) | 102591..102842 | - | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
| OU688_RS25315 (102854) | 102854..103051 | - | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| OU688_RS25320 (103038) | 103038..103628 | - | 591 | WP_000002778.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| OU688_RS25325 (103618) | 103618..105045 | - | 1428 | WP_032297072.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| OU688_RS25330 (105045) | 105045..105773 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| OU688_RS25335 (105760) | 105760..106326 | - | 567 | WP_000399794.1 | type IV conjugative transfer system protein TraE | - |
| OU688_RS25340 (106348) | 106348..106659 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| OU688_RS25345 (106674) | 106674..107039 | - | 366 | WP_021519752.1 | type IV conjugative transfer system pilin TraA | - |
| OU688_RS25350 (107073) | 107073..107300 | - | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| OU688_RS25355 (107394) | 107394..108080 | - | 687 | WP_015059009.1 | PAS domain-containing protein | - |
| OU688_RS25360 (108271) | 108271..108654 | - | 384 | WP_000124981.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| OU688_RS25365 (108931) | 108931..109578 | + | 648 | WP_015059008.1 | hypothetical protein | VF |
| OU688_RS25370 (109875) | 109875..110696 | - | 822 | WP_001234445.1 | DUF932 domain-containing protein | - |
| OU688_RS25375 (110807) | 110807..111103 | - | 297 | WP_001272251.1 | hypothetical protein | - |
| OU688_RS25380 (111403) | 111403..111699 | + | 297 | Protein_117 | hypothetical protein | - |
| OU688_RS25385 (112018) | 112018..112143 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| OU688_RS25390 (112085) | 112085..112234 | - | 150 | Protein_119 | plasmid maintenance protein Mok | - |
| OU688_RS25395 (112256) | 112256..112435 | + | 180 | WP_001309233.1 | hypothetical protein | - |
| - (112220) | 112220..112444 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (112220) | 112220..112444 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (112220) | 112220..112444 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (112220) | 112220..112444 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| OU688_RS25400 (112413) | 112413..113175 | - | 763 | Protein_121 | plasmid SOS inhibition protein A | - |
| OU688_RS25405 (113172) | 113172..113606 | - | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| OU688_RS25410 (113675) | 113675..115698 | - | 2024 | Protein_123 | ParB/RepB/Spo0J family partition protein | - |
| OU688_RS25415 (115759) | 115759..115992 | - | 234 | WP_000006003.1 | DUF905 family protein | - |
| OU688_RS25420 (116050) | 116050..116577 | - | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| OU688_RS25425 (116879) | 116879..117334 | + | 456 | Protein_126 | hypothetical protein | - |
| OU688_RS25430 (117420) | 117420..117983 | - | 564 | WP_001311069.1 | class I SAM-dependent methyltransferase | - |
| OU688_RS25435 (118030) | 118030..119391 | - | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| OU688_RS25440 (119443) | 119443..119673 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| OU688_RS25445 (120188) | 120188..120342 | + | 155 | Protein_130 | hypothetical protein | - |
| OU688_RS25450 (121071) | 121071..122738 | + | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
| OU688_RS25455 (122851) | 122851..122997 | + | 147 | Protein_132 | hypothetical protein | - |
| OU688_RS25460 (123083) | 123083..123646 | - | 564 | WP_001311069.1 | class I SAM-dependent methyltransferase | - |
| OU688_RS25465 (123693) | 123693..125054 | - | 1362 | WP_050008613.1 | DUF3560 domain-containing protein | - |
| OU688_RS25470 (125106) | 125106..125336 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| OU688_RS25475 (125850) | 125850..126004 | + | 155 | Protein_136 | hypothetical protein | - |
| OU688_RS25480 (126336) | 126336..126527 | - | 192 | WP_065800505.1 | hypothetical protein | - |
| OU688_RS25485 (126524) | 126524..126988 | - | 465 | WP_072657562.1 | DUF1380 family protein | - |
| OU688_RS25490 (126988) | 126988..127413 | - | 426 | WP_001198922.1 | antirestriction protein | - |
| OU688_RS25495 (127815) | 127815..128579 | + | 765 | Protein_140 | IS110 family transposase ISEc32 | Transposase |
| OU688_RS25505 (129341) | 129341..129676 | - | 336 | WP_000343070.1 | hypothetical protein | - |
| OU688_RS25510 (129745) | 129745..130092 | - | 348 | WP_001350917.1 | hypothetical protein | - |
| OU688_RS25515 (130089) | 130089..130258 | - | 170 | Protein_144 | hypothetical protein | - |
| OU688_RS25520 (131024) | 131024..131995 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| OU688_RS25525 (131995) | 131995..133161 | - | 1167 | WP_001238646.1 | hypothetical protein | VF |
| OU688_RS25535 (134314) | 134314..135816 | - | 1503 | WP_072657541.1 | hypothetical protein | - |
| OU688_RS25540 (136434) | 136434..136859 | - | 426 | WP_012300440.1 | hypothetical protein | - |
| OU688_RS25545 (137001) | 137001..137480 | + | 480 | WP_000190053.1 | hypothetical protein | - |
| OU688_RS25550 (137920) | 137920..138171 | + | 252 | WP_013362826.1 | hypothetical protein | - |
| OU688_RS25555 (138144) | 138144..138275 | - | 132 | Protein_152 | phosphopyruvate hydratase | - |
| OU688_RS25560 (138764) | 138764..139621 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| OU688_RS25565 (139618) | 139618..140475 | - | 858 | WP_000992806.1 | Manganese transport system membrane protein MntB | ARG |
| OU688_RS25570 (140472) | 140472..141299 | - | 828 | WP_000983710.1 | Manganese transport system ATP-binding protein MntB | VF |
| OU688_RS25575 (141299) | 141299..142213 | - | 915 | WP_000949004.1 | putative periplasmic iron-binding protein | VF |
| OU688_RS25580 (142569) | 142569..143266 | + | 698 | WP_103215986.1 | IS1-like element IS1A family transposase | - |
| OU688_RS25585 (143446) | 143446..143959 | - | 514 | Protein_158 | DUF4113 domain-containing protein | - |
| OU688_RS25590 (144020) | 144020..144124 | - | 105 | Protein_159 | AAA family ATPase | - |
| OU688_RS25595 (144126) | 144126..144449 | - | 324 | Protein_160 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|