NZ_CP1169821..156174

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 156174 bp
Accession: NZ_CP116982        Location: 1..156174         Organism: Escherichia coli strain E6474       Replicon: plasmid pE6474.1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PO910_RS23055 (1) 1..858 + 858 WP_039002220.1 incFII family plasmid replication initiator RepA -
PO910_RS23060 (1798) 1798..2451 + 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
PO910_RS23065 (2544) 2544..2801 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
PO910_RS23070 (2734) 2734..3135 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
PO910_RS23075 (3420) 3420..4727 + 1308 WP_094336907.1 DUF262 domain-containing protein -
PO910_RS23085 (6020) 6020..6118 + 99 Protein_6 IS1 family transposase -
PO910_RS23090 (6268) 6268..6564 - 297 Protein_7 serine hydrolase -
PO910_RS23095 (6629) 6629..6940 + 312 Protein_8 IS6 family transposase IS15DI Transposase
PO910_RS23100 (6995) 6995..7699 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
PO910_RS23105 (7879) 7879..8463 + 585 WP_000477040.1 fimbrial protein -
PO910_RS23110 (8516) 8516..9208 + 693 WP_001223973.1 putative fimbrial chaperone YehC VF
PO910_RS23115 (9224) 9224..11716 + 2493 WP_000782716.1 Outer membrane usher protein YehB VF
PO910_RS23120 (11732) 11732..12796 + 1065 WP_094336860.1 fimbrial protein -
PO910_RS23125 (12946) 12946..13650 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
PO910_RS23130 (13660) 13660..14373 + 714 WP_223419854.1 EamA family transporter -
PO910_RS23135 (14405) 14405..15604 - 1200 WP_001493765.1 Tetracycline resistance protein, class C ARG
PO910_RS23140 (15710) 15710..16360 + 651 WP_001493764.1 tetracycline resistance transcriptional repressor TetR(A) -
PO910_RS23145 (16392) 16392..16634 - 243 WP_000844627.1 transposase -
PO910_RS23150 (16692) 16692..19658 - 2967 WP_001138014.1 Tn3 family transposase TnpA_TnAs1 Transposase
PO910_RS23155 (19662) 19662..19775 - 114 Protein_20 helix-turn-helix domain-containing protein -
PO910_RS23160 (19839) 19839..20543 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
PO910_RS23165 (20595) 20595..21041 + 447 Protein_22 IS6 family transposase IS26 Transposase
PO910_RS23170 (21116) 21116..21502 + 387 WP_001039464.1 plasmid stabilization protein StbA -
PO910_RS23175 (21642) 21642..22610 - 969 WP_162722054.1 IS5 family transposase IS903B Transposase
PO910_RS23180 (23053) 23053..23760 + 708 Protein_25 translesion error-prone DNA polymerase V subunit UmuC -
PO910_RS23185 (23842) 23842..24816 - 975 WP_000064120.1 ParB family protein -
PO910_RS23190 (24816) 24816..26021 - 1206 WP_000368714.1 AAA family ATPase -
PO910_RS23195 (26436) 26436..26705 + 270 WP_000339857.1 hypothetical protein -
PO910_RS23200 (27026) 27026..27892 - 867 WP_004118283.1 replication initiation protein -
PO910_RS23205 (28427) 28427..28531 + 105 WP_032409716.1 hypothetical protein -
PO910_RS23210 (28660) 28660..28917 + 258 WP_000764642.1 hypothetical protein -
PO910_RS23215 (28975) 28975..29751 - 777 WP_000015958.1 site-specific integrase -
PO910_RS23220 (29748) 29748..30491 - 744 WP_000129823.1 hypothetical protein -
PO910_RS23225 (30542) 30542..30892 - 351 WP_004118279.1 hypothetical protein -
PO910_RS23230 (31460) 31460..32434 - 975 WP_001148756.1 sensor domain-containing diguanylate cyclase -
PO910_RS23235 (33071) 33071..33979 + 909 Protein_36 HNH endonuclease -
PO910_RS23240 (34367) 34367..34717 - 351 WP_000694953.1 DUF305 domain-containing protein -
PO910_RS23245 (34861) 34861..35292 - 432 WP_000790483.1 silver-binding protein SilE -
PO910_RS23250 (35543) 35543..37018 - 1476 WP_000555737.1 copper/silver sensor histidine kinase SilS -
PO910_RS23255 (37011) 37011..37691 - 681 WP_000697969.1 Transcriptional regulatory protein CusR VF
PO910_RS23260 (37881) 37881..39266 + 1386 WP_000475512.1 Cation efflux system protein CusC VF
PO910_RS23265 (39294) 39294..39647 + 354 WP_001246155.1 cation efflux system protein CusF -
PO910_RS23270 (39761) 39761..41053 + 1293 WP_001398209.1 Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB -
PO910_RS23275 (41064) 41064..44210 + 3147 WP_000574035.1 Cu(+)/Ag(+) efflux RND transporter permease subunit SilA -
PO910_RS23280 (44297) 44297..44737 + 441 WP_000758221.1 DUF411 domain-containing protein -
PO910_RS23285 (44834) 44834..47311 + 2478 WP_001398208.1 Ag(+)-translocating P-type ATPase SilP -
PO910_RS23290 (47352) 47352..47549 + 198 WP_000843496.1 DUF2933 domain-containing protein -
PO910_RS23295 (47583) 47583..48314 - 732 WP_094336930.1 peptidoglycan DD-metalloendopeptidase family protein -
PO910_RS23305 (49350) 49350..52055 + 2706 WP_016240421.1 HTH-type transcriptional regulator MalT VF
PO910_RS23310 (52098) 52098..52451 - 354 Protein_51 RNA 3'-terminal phosphate cyclase -
PO910_RS23315 (52859) 52859..53803 - 945 Protein_52 IS110 family transposase IS5708 Transposase
PO910_RS23320 (53871) 53871..54575 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
PO910_RS23325 (54778) 54778..55092 + 315 WP_015060479.1 hypothetical protein -
PO910_RS23330 (57226) 57226..57384 + 159 Protein_55 replication initiation protein -
PO910_RS23335 (57978) 57978..58958 - 981 WP_109548742.1 IS5 family transposase ISKpn26 Transposase
PO910_RS23340 (59714) 59714..60490 + 777 WP_039052454.1 hypothetical protein -
PO910_RS23345 (60492) 60492..62756 + 2265 WP_015060475.1 UvrD-helicase domain-containing protein -
PO910_RS23350 (63174) 63174..63245 - 72 Protein_59 hypothetical protein -
PO910_RS23355 (63229) 63229..63459 + 231 WP_001261274.1 type II toxin-antitoxin system VapB family antitoxin -
PO910_RS23360 (63456) 63456..63772 + 317 Protein_61 type II toxin-antitoxin system VapC family toxin -
PO910_RS23365 (63828) 63828..64045 - 218 Protein_62 transposase -
PO910_RS23370 (64046) 64046..64576 - 531 WP_000348883.1 GNAT family N-acetyltransferase Toxin Detail
PO910_RS23375 (64580) 64580..64849 - 270 WP_001275013.1 DUF1778 domain-containing protein Antitoxin Detail
PO910_RS23380 (65104) 65104..65801 + 698 WP_103215986.1 IS1 family transposase IS1G Transposase
PO910_RS23385 (66075) 66075..66618 + 544 Protein_66 fimbrial protein -
PO910_RS23390 (66671) 66671..67363 + 693 WP_001223973.1 putative fimbrial chaperone YehC VF
PO910_RS23395 (67379) 67379..69871 + 2493 WP_000782716.1 Outer membrane usher protein YehB VF
PO910_RS23400 (69887) 69887..70552 + 666 Protein_69 fimbrial protein -
PO910_RS23405 (70620) 70620..71324 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
PO910_RS23410 (71422) 71422..72054 + 633 WP_020802982.1 IS256 family transposase IS406 Transposase
PO910_RS23415 (72301) 72301..72633 - 333 WP_000800531.1 quaternary ammonium compound efflux SMR transporter QacL -
PO910_RS23420 (72756) 72756..73594 - 839 Protein_73 Streptomycin 3''-adenylyltransferase ARG
PO910_RS23425 (73687) 73687..74946 - 1260 WP_000095725.1 chloramphenicol efflux MFS transporter CmlA1 ARG
PO910_RS23430 (75161) 75161..75999 - 839 Protein_75 Streptomycin 3''-adenylyltransferase ARG
PO910_RS23435 (76005) 76005..76295 - 291 WP_001336345.1 DUF1010 domain-containing protein -
PO910_RS23440 (76407) 76407..76904 - 498 WP_001083725.1 IS1595 family transposase ISSsu9 ARG
PO910_RS23445 (77049) 77049..78062 + 1014 WP_000845039.1 IS91 family transposase ISAzo26 Transposase
PO910_RS23450 (78265) 78265..78615 + 351 WP_000454193.1 DUF3330 domain-containing protein -
PO910_RS23455 (78791) 78791..79351 + 561 WP_001161490.1 Tn3 family transposase TnpR_TnAs1 Transposase
PO910_RS23460 (79355) 79355..82321 + 2967 WP_001138014.1 Tn3 family transposase TnpA_TnAs1 Transposase
PO910_RS23465 (82554) 82554..82961 - 408 WP_034167712.1 hypothetical protein -
PO910_RS23470 (83023) 83023..83220 + 198 WP_032482496.1 DUF2384 domain-containing protein -
PO910_RS23475 (83419) 83419..83634 - 216 WP_034167711.1 hypothetical protein -
PO910_RS23480 (84069) 84069..84278 + 210 Protein_85 hypothetical protein -
PO910_RS23485 (84403) 84403..85317 - 915 Protein_86 IS5 family transposase ISKpn26 Transposase
PO910_RS23490 (85680) 85680..86651 - 972 WP_032482493.1 IS91 family transposase ISAzo26 Transposase
PO910_RS23495 (87054) 87054..87686 - 633 WP_020802982.1 IS256 family transposase IS406 Transposase
PO910_RS23500 (87709) 87709..87984 + 276 WP_109023896.1 hypothetical protein -
PO910_RS23505 (87987) 87987..88778 - 792 WP_000034420.1 Dihydropteroate synthase ARG
PO910_RS23510 (89247) 89247..89492 - 246 WP_001354008.1 GrpB family protein -
PO910_RS23515 (89530) 89530..90393 - 864 WP_000612791.1 SDR family oxidoreductase -
PO910_RS23520 (90539) 90539..90796 - 258 Protein_93 hypothetical protein -
PO910_RS23525 (90851) 90851..91555 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
PO910_RS23530 (91621) 91621..92103 + 483 Protein_95 IS3 family transposase IS629 Transposase
PO910_RS23535 (92146) 92146..92964 - 819 Protein_96 IS30 family transposase IS30D Transposase
PO910_RS23540 (93032) 93032..93925 + 894 Protein_97 IS3 family transposase ISEhe3 Transposase
PO910_RS23545 (94027) 94027..94308 + 282 WP_000639434.1 hypothetical protein -
PO910_RS23555 (95216) 95216..96541 + 1326 WP_021512928.1 reactive chlorine resistance oxidoreductase RclA -
PO910_RS23560 (96690) 96690..97394 - 705 WP_001505086.1 IS6 family transposase IS26 Transposase
PO910_RS23565 (97385) 97385..97891 + 507 WP_001505085.1 hypothetical protein -
PO910_RS23570 (97888) 97888..98664 + 777 Protein_103 site-specific integrase -
PO910_RS23575 (98816) 98816..99091 - 276 WP_000239529.1 hypothetical protein -
PO910_RS23580 (99085) 99085..99729 - 645 WP_000633913.1 division plane positioning ATPase MipZ -
PO910_RS23585 (99951) 99951..100922 + 972 WP_001103690.1 plasmid segregation protein ParM -
PO910_RS23590 (100927) 100927..101319 + 393 WP_000340829.1 plasmid partitioning/stability family protein -
PO910_RS23595 (101324) 101324..102595 - 1272 WP_000457518.1 Y-family DNA polymerase -
PO910_RS23600 (102595) 102595..103032 - 438 WP_000109071.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
PO910_RS23605 (103143) 103143..103277 - 135 WP_001493841.1 DinI-like family protein -
PO910_RS23610 (103695) 103695..104597 + 903 WP_001348615.1 DUF1281 domain-containing protein -
PO910_RS23615 (104594) 104594..104905 + 312 WP_011254640.1 hypothetical protein -
PO910_RS23620 (104982) 104982..105665 + 684 WP_000086185.1 DNA methylase -
PO910_RS23625 (105666) 105666..105887 + 222 WP_001104873.1 hypothetical protein -
PO910_RS23630 (105817) 105817..106335 + 519 WP_123325260.1 DUF1380 family protein -
PO910_RS23635 (106386) 106386..107162 + 777 WP_001753849.1 hypothetical protein -
PO910_RS23640 (107579) 107579..108004 + 426 WP_001198928.1 antirestriction protein -
PO910_RS23645 (108051) 108051..108473 + 423 WP_000271753.1 DUF1380 family protein -
PO910_RS23650 (108470) 108470..108661 + 192 WP_001027516.1 hypothetical protein -
PO910_RS23655 (109696) 109696..109926 + 231 WP_000218642.1 hypothetical protein -
PO910_RS23660 (109978) 109978..111339 + 1362 WP_038999961.1 DUF3560 domain-containing protein -
PO910_RS23665 (111387) 111387..111950 + 564 WP_001315564.1 class I SAM-dependent methyltransferase -
PO910_RS23670 (112102) 112102..112329 + 228 WP_071961421.1 hypothetical protein -
PO910_RS23675 (112570) 112570..112830 + 261 WP_244578321.1 single-stranded DNA-binding protein -
PO910_RS23680 (112924) 112924..113928 - 1005 WP_024257664.1 IS110 family transposase IS1663 Transposase
PO910_RS23685 (114180) 114180..114719 + 540 WP_032332913.1 single-stranded DNA-binding protein -
PO910_RS23690 (114776) 114776..115009 + 234 WP_000005987.1 DUF905 family protein -
PO910_RS23695 (115074) 115074..117032 + 1959 WP_039000998.1 ParB/RepB/Spo0J family partition protein -
PO910_RS23700 (117087) 117087..117521 + 435 WP_000845953.1 conjugation system SOS inhibitor PsiB -
PO910_RS23705 (117518) 117518..118280 + 763 Protein_130 plasmid SOS inhibition protein A -
PO910_RS23710 (118249) 118249..118437 - 189 WP_001299721.1 hypothetical protein -
- (118249) 118249..118473 + 225 NuclAT_0 - Antitoxin Detail
- (118249) 118249..118473 + 225 NuclAT_0 - Antitoxin Detail
- (118249) 118249..118473 + 225 NuclAT_0 - Antitoxin Detail
- (118249) 118249..118473 + 225 NuclAT_0 - Antitoxin Detail
PO910_RS23715 (118459) 118459..118608 + 150 Protein_132 plasmid maintenance protein Mok -
PO910_RS23720 (118550) 118550..118675 + 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
PO910_RS23725 (118895) 118895..119125 + 231 WP_001426396.1 hypothetical protein -
PO910_RS23730 (119123) 119123..119296 - 174 Protein_135 hypothetical protein -
PO910_RS23735 (119366) 119366..119626 + 261 WP_042046747.1 hypothetical protein -
PO910_RS23740 (119720) 119720..120724 - 1005 WP_024257664.1 IS110 family transposase IS1663 Transposase
PO910_RS23745 (120975) 120975..121262 + 288 WP_000107535.1 hypothetical protein -
PO910_RS23750 (121383) 121383..122204 + 822 WP_001234469.1 DUF932 domain-containing protein -
PO910_RS23755 (122501) 122501..123103 - 603 WP_097738799.1 hypothetical protein VF
PO910_RS23760 (123424) 123424..123807 + 384 WP_001151524.1 conjugal transfer relaxosome DNA-binding protein TraM -
PO910_RS23765 (123994) 123994..124683 + 690 WP_039002187.1 conjugal transfer transcriptional regulator TraJ -
PO910_RS23770 (124776) 124776..125177 + 402 WP_001369361.1 conjugal transfer relaxosome DNA-bindin protein TraY -
PO910_RS23775 (125210) 125210..125572 + 363 WP_000994784.1 type IV conjugative transfer system pilin TraA -
PO910_RS23780 (125577) 125577..125888 + 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
PO910_RS23785 (125910) 125910..126476 + 567 WP_000399792.1 type IV conjugative transfer system protein TraE -
PO910_RS23790 (126463) 126463..127191 + 729 WP_001230787.1 type-F conjugative transfer system secretin TraK -
PO910_RS23795 (127191) 127191..128618 + 1428 WP_000146690.1 F-type conjugal transfer pilus assembly protein TraB -
PO910_RS23800 (128608) 128608..129195 + 588 WP_000002772.1 conjugal transfer pilus-stabilizing protein TraP -
PO910_RS23805 (129182) 129182..129502 + 321 WP_001057285.1 conjugal transfer protein TrbD -
PO910_RS23810 (129499) 129499..130014 + 516 WP_000724019.1 type IV conjugative transfer system lipoprotein TraV -
PO910_RS23815 (130149) 130149..130370 + 222 WP_001278692.1 conjugal transfer protein TraR -
PO910_RS23820 (130530) 130530..133157 + 2628 WP_001064265.1 type IV secretion system protein TraC -
PO910_RS23825 (133154) 133154..133540 + 387 WP_039002198.1 type-F conjugative transfer system protein TrbI -
PO910_RS23830 (133537) 133537..134169 + 633 WP_001749440.1 type-F conjugative transfer system protein TraW -
PO910_RS23835 (134166) 134166..135158 + 993 WP_023148235.1 conjugal transfer pilus assembly protein TraU -
PO910_RS23840 (135167) 135167..135805 + 639 WP_000777691.1 type-F conjugative transfer system pilin assembly protein TrbC -
PO910_RS23845 (135802) 135802..137610 + 1809 WP_000821844.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
PO910_RS23850 (137637) 137637..137897 + 261 WP_000864348.1 conjugal transfer protein TrbE -
PO910_RS23855 (137890) 137890..138633 + 744 WP_039002205.1 type-F conjugative transfer system pilin assembly protein TraF -
PO910_RS23860 (138794) 138794..139030 + 237 WP_054377141.1 type-F conjugative transfer system pilin chaperone TraQ -
PO910_RS23865 (139017) 139017..139562 + 546 WP_000052613.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
PO910_RS23870 (139492) 139492..139854 + 363 WP_001443292.1 P-type conjugative transfer protein TrbJ -
PO910_RS23875 (139854) 139854..141227 + 1374 WP_170926237.1 conjugal transfer pilus assembly protein TraH -
PO910_RS23880 (141224) 141224..144046 + 2823 WP_001007048.1 conjugal transfer mating-pair stabilization protein TraG -
PO910_RS23885 (144061) 144061..144564 + 504 WP_000605510.1 hypothetical protein -
PO910_RS23890 (144596) 144596..145327 + 732 WP_000850424.1 conjugal transfer complement resistance protein TraT -
PO910_RS23895 (145580) 145580..147760 + 2181 WP_063078088.1 type IV conjugative transfer system coupling protein TraD -
PO910_RS23900 (147760) 147760..153030 + 5271 WP_054377139.1 Multifunctional conjugation protein TraI Relaxase
PO910_RS23905 (153050) 153050..153793 + 744 WP_039002216.1 conjugal transfer pilus acetylase TraX -
PO910_RS23910 (153848) 153848..154408 + 561 WP_000139310.1 fertility inhibition protein FinO -
PO910_RS23915 (154543) 154543..154755 + 213 WP_001541896.1 ANR family transcriptional regulator -
- (155097) 155097..155158 - 62 NuclAT_1 - Antitoxin Detail
- (155097) 155097..155158 - 62 NuclAT_1 - Antitoxin Detail
- (155097) 155097..155158 - 62 NuclAT_1 - Antitoxin Detail
- (155097) 155097..155158 - 62 NuclAT_1 - Antitoxin Detail
PO910_RS23920 (155202) 155202..155351 + 150 WP_001312851.1 Hok/Gef family protein Toxin Detail
PO910_RS23925 (155619) 155619..155876 + 258 WP_001541895.1 replication regulatory protein RepA -
PO910_RS23930 (155979) 155979..156162 + 184 Protein_175 plasmid copy control protein CopA -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance