MGE detailed information
MGE type: Mobilizable plasmid MGE length: 134875 bp
Accession: NZ_CP116905 Location: 1..134875 Organism: Klebsiella pneumoniae strain KP2722 Replicon: plasmid pKP2722-2
Accession: NZ_CP116905 Location: 1..134875 Organism: Klebsiella pneumoniae strain KP2722 Replicon: plasmid pKP2722-2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PO783_RS28940 (3191) | 3191..3631 | + | 441 | WP_000758228.1 | DUF411 domain-containing protein | - |
| PO783_RS28945 (3758) | 3758..6205 | + | 2448 | WP_004098955.1 | Ag(+)-translocating P-type ATPase SilP | - |
| PO783_RS28950 (6246) | 6246..6443 | + | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| PO783_RS28955 (6477) | 6477..7214 | - | 738 | WP_004118669.1 | Murein DD-endopeptidase MepM | VF |
| PO783_RS28960 (7481) | 7481..7948 | - | 468 | WP_048336866.1 | hypothetical protein | - |
| PO783_RS28965 (8182) | 8182..9999 | + | 1818 | WP_004213580.1 | multicopper oxidase PcoA | - |
| PO783_RS28970 (10005) | 10005..10895 | + | 891 | WP_029884201.1 | copper resistance outer membrane transporter PcoB | - |
| PO783_RS28975 (10935) | 10935..11315 | + | 381 | WP_000025662.1 | copper resistance system metallochaperone PcoC | - |
| PO783_RS28980 (11320) | 11320..12249 | + | 930 | WP_004213583.1 | copper resistance inner membrane protein PcoD | - |
| PO783_RS28985 (12304) | 12304..12984 | + | 681 | WP_001188930.1 | Transcriptional activator protein CopR | VF |
| PO783_RS28990 (12981) | 12981..14381 | + | 1401 | WP_004152084.1 | copper resistance membrane spanning protein PcoS | - |
| PO783_RS28995 (14909) | 14909..15913 | - | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| PO783_RS29000 (15992) | 15992..16426 | - | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| PO783_RS29005 (16498) | 16498..16848 | + | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| PO783_RS29010 (16862) | 16862..17137 | + | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| PO783_RS29015 (17173) | 17173..17595 | + | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| PO783_RS29020 (17647) | 17647..19341 | + | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| PO783_RS29025 (19359) | 19359..19721 | + | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| PO783_RS29030 (19718) | 19718..19954 | + | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| PO783_RS29035 (19990) | 19990..20658 | + | 669 | WP_001300294.1 | putative signaling protein | VF |
| PO783_RS29040 (20733) | 20733..21905 | + | 1173 | Protein_21 | transposase | - |
| PO783_RS29045 (21970) | 21970..22674 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PO783_RS29050 (22726) | 22726..23187 | + | 462 | Protein_23 | Tn3 family transposase TnpR_Tn3 | Transposase |
| PO783_RS29055 (23310) | 23310..24290 | + | 981 | WP_013213985.1 | IS481 family transposase ISKpn27 | Transposase |
| PO783_RS29060 (24566) | 24566..25447 | + | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| PO783_RS29065 (25697) | 25697..26578 | - | 882 | Protein_26 | IS1182 family transposase ISKpn6 | Transposase |
| PO783_RS29070 (26682) | 26682..26978 | - | 297 | WP_013213987.1 | transcriptional regulator | - |
| PO783_RS29075 (27024) | 27024..27179 | - | 156 | WP_013213988.1 | hypothetical protein | - |
| PO783_RS29080 (27307) | 27307..27732 | - | 426 | WP_013213989.1 | antirestriction protein | - |
| PO783_RS29085 (27843) | 27843..28121 | - | 279 | WP_013213990.1 | hypothetical protein | - |
| PO783_RS29090 (28655) | 28655..29272 | - | 618 | Protein_31 | replication protein | - |
| PO783_RS29095 (29664) | 29664..30224 | + | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| PO783_RS29100 (30228) | 30228..33194 | + | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| PO783_RS29105 (33230) | 33230..33298 | - | 69 | Protein_34 | IS6 family transposase | - |
| PO783_RS29110 (33435) | 33435..34295 | + | 861 | WP_002904004.1 | Beta-lactamase SHV-2 | ARG |
| PO783_RS29115 (34316) | 34316..35077 | - | 762 | WP_002210513.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| PO783_RS29120 (35339) | 35339..36241 | + | 903 | WP_002903955.1 | NAD(P)-dependent oxidoreductase | - |
| PO783_RS29125 (36253) | 36253..37505 | + | 1253 | Protein_38 | four-carbon acid sugar kinase family protein | - |
| PO783_RS29130 (37498) | 37498..37821 | + | 324 | Protein_39 | class II aldolase/adducin family protein | - |
| PO783_RS29135 (37875) | 37875..38579 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PO783_RS29140 (38860) | 38860..39243 | - | 384 | WP_000124981.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| PO783_RS29145 (39520) | 39520..40167 | + | 648 | WP_272525575.1 | hypothetical protein | VF |
| PO783_RS29150 (40464) | 40464..41285 | - | 822 | WP_001234445.1 | DUF932 domain-containing protein | - |
| PO783_RS29155 (41396) | 41396..41692 | - | 297 | WP_001272251.1 | hypothetical protein | - |
| PO783_RS29160 (41992) | 41992..42288 | + | 297 | Protein_45 | hypothetical protein | - |
| PO783_RS29165 (42607) | 42607..42732 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| PO783_RS29170 (42674) | 42674..42823 | - | 150 | Protein_47 | plasmid maintenance protein Mok | - |
| - (42809) | 42809..43033 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (42809) | 42809..43033 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (42809) | 42809..43033 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (42809) | 42809..43033 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| PO783_RS29175 (43045) | 43045..43764 | - | 720 | WP_001276217.1 | plasmid SOS inhibition protein A | - |
| PO783_RS29180 (43761) | 43761..44195 | - | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| PO783_RS29185 (44264) | 44264..46287 | - | 2024 | Protein_50 | ParB/RepB/Spo0J family partition protein | - |
| PO783_RS29190 (46348) | 46348..46581 | - | 234 | WP_000006003.1 | DUF905 family protein | - |
| PO783_RS29195 (46639) | 46639..47166 | - | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| PO783_RS29200 (47468) | 47468..47923 | + | 456 | Protein_53 | hypothetical protein | - |
| PO783_RS29205 (48009) | 48009..48572 | - | 564 | WP_015059007.1 | class I SAM-dependent methyltransferase | - |
| PO783_RS29210 (48619) | 48619..49980 | - | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| PO783_RS29215 (50032) | 50032..50262 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| PO783_RS29220 (50779) | 50779..50933 | + | 155 | Protein_57 | hypothetical protein | - |
| PO783_RS29225 (51662) | 51662..53329 | + | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
| PO783_RS29230 (53643) | 53643..53834 | - | 192 | WP_001027493.1 | hypothetical protein | - |
| PO783_RS29235 (53831) | 53831..54253 | - | 423 | WP_000271762.1 | DUF1380 family protein | - |
| PO783_RS29240 (54300) | 54300..54725 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| PO783_RS29245 (55143) | 55143..55919 | - | 777 | WP_001383963.1 | hypothetical protein | - |
| PO783_RS29250 (55970) | 55970..56404 | - | 435 | WP_000274503.1 | DUF1380 family protein | - |
| PO783_RS29255 (56418) | 56418..56639 | - | 222 | WP_001104881.1 | hypothetical protein | - |
| PO783_RS29260 (56640) | 56640..57323 | - | 684 | WP_000085883.1 | DNA methylase | - |
| PO783_RS29265 (57400) | 57400..57699 | - | 300 | WP_272525577.1 | hypothetical protein | - |
| PO783_RS29270 (57841) | 57841..58803 | + | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| PO783_RS29275 (58806) | 58806..59156 | + | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| PO783_RS29280 (59279) | 59279..59560 | - | 282 | WP_001333089.1 | hypothetical protein | - |
| PO783_RS29285 (59688) | 59688..59922 | - | 235 | Protein_70 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| PO783_RS29290 (61371) | 61371..61436 | - | 66 | Protein_71 | IS1 family transposase | - |
| PO783_RS29295 (61502) | 61502..62206 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| PO783_RS29300 (62261) | 62261..62575 | + | 315 | Protein_73 | hypothetical protein | - |
| PO783_RS29305 (62656) | 62656..63411 | - | 756 | WP_012372818.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase | ARG |
| PO783_RS29310 (63581) | 63581..64441 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| PO783_RS29315 (64624) | 64624..65160 | - | 537 | WP_064441864.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| PO783_RS29320 (65252) | 65252..65440 | + | 189 | WP_000957857.1 | hypothetical protein | - |
| PO783_RS29325 (65450) | 65450..66067 | + | 618 | Protein_78 | IS91 family transposase ISSbo1 | Transposase |
| PO783_RS29330 (66118) | 66118..66822 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PO783_RS29335 (67278) | 67278..67868 | - | 591 | Protein_80 | IS91 family transposase ISSbo1 | Transposase |
| PO783_RS29340 (67933) | 67933..68637 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PO783_RS29345 (68690) | 68690..69166 | + | 477 | Protein_82 | PAS domain-containing protein | - |
| PO783_RS29350 (69234) | 69234..70331 | - | 1098 | Protein_83 | TonB-dependent receptor | - |
| PO783_RS29355 (70388) | 70388..71356 | - | 969 | WP_013362812.1 | IS5 family transposase IS903B | Transposase |
| PO783_RS29360 (71391) | 71391..72266 | - | 876 | WP_013188475.1 | Beta-lactamase Toho-1 | ARG |
| PO783_RS29365 (72516) | 72516..72707 | - | 192 | Protein_86 | IS1380 family transposase | - |
| PO783_RS29370 (72777) | 72777..73481 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PO783_RS29375 (73547) | 73547..74092 | + | 546 | Protein_88 | Tn3 family transposase TnpA_Tn3 | Transposase |
| PO783_RS29380 (74128) | 74128..74543 | - | 416 | Protein_89 | IS1-like element IS1B family transposase | - |
| PO783_RS29385 (74792) | 74792..75193 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| PO783_RS29390 (75126) | 75126..75383 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| PO783_RS29395 (75476) | 75476..76129 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| PO783_RS29400 (77068) | 77068..77925 | - | 858 | WP_032495102.1 | incFII family plasmid replication initiator RepA | - |
| PO783_RS29405 (77918) | 77918..77992 | - | 75 | WP_001375168.1 | RepA leader peptide Tap | - |
| PO783_RS29410 (78237) | 78237..78485 | - | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
| PO783_RS29415 (78769) | 78769..78918 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (78963) | 78963..79022 | + | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (78963) | 78963..79022 | + | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (78963) | 78963..79022 | + | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (78963) | 78963..79022 | + | 60 | NuclAT_1 | - | Antitoxin Detail |
| PO783_RS29420 (79223) | 79223..79555 | - | 333 | WP_152916585.1 | hypothetical protein | - |
| PO783_RS29425 (79617) | 79617..80216 | - | 600 | WP_032083981.1 | PIN domain-containing protein | - |
| PO783_RS29430 (80602) | 80602..80802 | - | 201 | WP_015059022.1 | hypothetical protein | - |
| PO783_RS29435 (80934) | 80934..81494 | - | 561 | WP_000139328.1 | fertility inhibition protein FinO | - |
| PO783_RS29440 (81549) | 81549..82295 | - | 747 | WP_000205770.1 | conjugal transfer pilus acetylase TraX | - |
| PO783_RS29445 (82315) | 82315..82515 | - | 201 | WP_072354025.1 | hypothetical protein | - |
| PO783_RS29450 (82540) | 82540..83244 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PO783_RS29455 (83296) | 83296..83640 | + | 345 | Protein_104 | IS6 family transposase IS26 | Transposase |
| PO783_RS29460 (83695) | 83695..84060 | - | 366 | Protein_105 | type IV conjugative transfer system protein TraE | - |
| PO783_RS29465 (84080) | 84080..84385 | - | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| PO783_RS29470 (84399) | 84399..84767 | - | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| PO783_RS29475 (84829) | 84829..85035 | - | 207 | WP_171773970.1 | TraY domain-containing protein | - |
| PO783_RS29480 (85150) | 85150..85887 | - | 738 | WP_154244330.1 | conjugal transfer protein TrbJ | - |
| PO783_RS29485 (86087) | 86087..86503 | - | 417 | WP_014343494.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| PO783_RS29490 (86894) | 86894..87379 | + | 486 | WP_014343495.1 | hypothetical protein | VF |
| PO783_RS29495 (87412) | 87412..87741 | - | 330 | WP_013214015.1 | DUF5983 family protein | - |
| PO783_RS29500 (87774) | 87774..88595 | - | 822 | WP_004152492.1 | DUF932 domain-containing protein | - |
| PO783_RS29505 (89424) | 89424..89528 | - | 105 | Protein_114 | transcriptional regulator | - |
| PO783_RS29510 (89532) | 89532..89810 | - | 279 | WP_004152721.1 | helix-turn-helix transcriptional regulator | - |
| PO783_RS29515 (89800) | 89800..90120 | - | 321 | WP_014343498.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| PO783_RS29520 (90201) | 90201..90425 | - | 225 | WP_014343499.1 | hypothetical protein | - |
| PO783_RS29525 (90436) | 90436..90648 | - | 213 | WP_014343500.1 | hypothetical protein | - |
| PO783_RS29530 (90709) | 90709..91065 | - | 357 | WP_014343501.1 | hypothetical protein | - |
| PO783_RS29535 (91906) | 91906..92223 | - | 318 | WP_014343505.1 | hypothetical protein | - |
| PO783_RS29540 (92238) | 92238..92588 | - | 351 | WP_040245917.1 | hypothetical protein | - |
| PO783_RS29545 (92585) | 92585..92857 | - | 273 | WP_040245921.1 | hypothetical protein | - |
| PO783_RS29550 (93550) | 93550..93648 | - | 99 | WP_159224797.1 | Hok/Gef family protein | - |
| PO783_RS29555 (93623) | 93623..93679 | - | 57 | Protein_124 | modulator protein | - |
| PO783_RS29560 (93780) | 93780..94853 | + | 1074 | WP_013609528.1 | IS481 family transposase ISKpn28 | Transposase |
| PO783_RS29565 (95037) | 95037..95411 | - | 375 | WP_014343510.1 | hypothetical protein | - |
| PO783_RS29570 (95467) | 95467..95793 | - | 327 | WP_013023807.1 | hypothetical protein | - |
| PO783_RS29575 (95790) | 95790..96518 | - | 729 | WP_001568058.1 | plasmid SOS inhibition protein A | - |
| PO783_RS29580 (96515) | 96515..96946 | - | 432 | WP_001568057.1 | conjugation system SOS inhibitor PsiB | - |
| PO783_RS29585 (96991) | 96991..99048 | - | 2058 | WP_015493064.1 | ParB/RepB/Spo0J family partition protein | - |
| PO783_RS29590 (99118) | 99118..99366 | - | 249 | WP_001568055.1 | DUF905 domain-containing protein | - |
| PO783_RS29595 (99415) | 99415..99957 | - | 543 | WP_014343512.1 | single-stranded DNA-binding protein | - |
| PO783_RS29600 (100790) | 100790..101353 | - | 564 | WP_014343514.1 | methyltransferase | - |
| PO783_RS29605 (101401) | 101401..102756 | - | 1356 | WP_014343515.1 | DUF3560 domain-containing protein | - |
| PO783_RS29610 (102808) | 102808..103038 | - | 231 | WP_001568051.1 | hypothetical protein | - |
| PO783_RS29615 (103130) | 103130..103357 | - | 228 | WP_001568050.1 | hypothetical protein | - |
| PO783_RS29620 (104037) | 104037..104357 | - | 321 | WP_001568049.1 | hypothetical protein | - |
| PO783_RS29625 (104392) | 104392..104646 | - | 255 | WP_011977779.1 | DNA polymerase III subunit theta | - |
| PO783_RS29630 (104834) | 104834..105025 | - | 192 | WP_001568047.1 | hypothetical protein | - |
| PO783_RS29635 (105068) | 105068..105574 | - | 507 | WP_013214014.1 | antirestriction protein ArdA | - |
| PO783_RS29640 (105617) | 105617..106045 | - | 429 | WP_004152356.1 | antirestriction protein | - |
| PO783_RS29645 (106726) | 106726..107493 | - | 768 | WP_013214013.1 | hypothetical protein | - |
| PO783_RS29650 (107547) | 107547..107966 | - | 420 | WP_001568043.1 | DUF1380 domain-containing protein | - |
| PO783_RS29655 (107976) | 107976..108197 | - | 222 | WP_001568042.1 | hypothetical protein | - |
| PO783_RS29660 (108197) | 108197..108898 | - | 702 | WP_001568041.1 | DNA methylase | - |
| PO783_RS29665 (108970) | 108970..109139 | - | 170 | Protein_146 | hypothetical protein | - |
| PO783_RS29670 (109335) | 109335..109565 | - | 231 | WP_001568040.1 | hypothetical protein | - |
| PO783_RS29675 (109629) | 109629..110300 | - | 672 | WP_015345000.1 | plasmid partitioning/stability family protein | - |
| PO783_RS29680 (110303) | 110303..111274 | - | 972 | WP_032425559.1 | plasmid segregation protein ParM | - |
| PO783_RS29685 (111523) | 111523..113010 | - | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| PO783_RS29690 (113417) | 113417..113848 | + | 432 | WP_001568036.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| PO783_RS29695 (113848) | 113848..115119 | + | 1272 | WP_013214011.1 | Y-family DNA polymerase | - |
| PO783_RS29700 (115201) | 115201..116175 | - | 975 | WP_011977819.1 | ParB family protein | - |
| PO783_RS29705 (116175) | 116175..117380 | - | 1206 | WP_011977818.1 | AAA family ATPase | - |
| PO783_RS29710 (118490) | 118490..119356 | - | 867 | WP_004118283.1 | replication initiation protein | - |
| PO783_RS29715 (119892) | 119892..120005 | + | 114 | WP_014343462.1 | hypothetical protein | - |
| PO783_RS29720 (120134) | 120134..120391 | + | 258 | WP_013214010.1 | hypothetical protein | - |
| PO783_RS29725 (120437) | 120437..121216 | - | 780 | WP_013214009.1 | site-specific integrase | - |
| PO783_RS29730 (121400) | 121400..122404 | - | 1005 | WP_011977814.1 | hypothetical protein | - |
| PO783_RS29735 (122434) | 122434..122637 | - | 204 | WP_011977813.1 | hypothetical protein | - |
| PO783_RS29740 (122683) | 122683..123204 | - | 522 | WP_013214008.1 | hypothetical protein | - |
| PO783_RS29745 (123262) | 123262..123654 | - | 393 | WP_011977811.1 | hypothetical protein | - |
| PO783_RS29750 (123691) | 123691..124635 | - | 945 | WP_011977810.1 | hypothetical protein | - |
| PO783_RS29755 (124796) | 124796..125041 | - | 246 | Protein_164 | hypothetical protein | - |
| PO783_RS29760 (125220) | 125220..126194 | - | 975 | WP_004213565.1 | sensor domain-containing diguanylate cyclase | - |
| PO783_RS29765 (126831) | 126831..127739 | + | 909 | WP_023302803.1 | HNH endonuclease | - |
| PO783_RS29770 (128126) | 128126..128476 | - | 351 | WP_004213569.1 | DUF305 domain-containing protein | - |
| PO783_RS29775 (128620) | 128620..129051 | - | 432 | WP_023302802.1 | silver-binding protein SilE | - |
| PO783_RS29780 (129302) | 129302..130777 | - | 1476 | WP_000555737.1 | copper/silver sensor histidine kinase SilS | - |
| PO783_RS29785 (130770) | 130770..131450 | - | 681 | WP_004213574.1 | Transcriptional regulatory protein CusR | VF |
| PO783_RS29790 (131640) | 131640..133025 | + | 1386 | WP_004213577.1 | Cation efflux system protein CusC | VF |
| PO783_RS29795 (133054) | 133054..133416 | + | 363 | WP_004213578.1 | cation efflux system protein CusF | - |
| PO783_RS29800 (133530) | 133530..134822 | + | 1293 | WP_004213579.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|