MGE detailed information
MGE type: Conjugative plasmid MGE length: 70464 bp
Accession: NZ_CP116077 Location: 1..70464 Organism: Escherichia coli strain DETEC-S586 Replicon: plasmid pDETEC48
Accession: NZ_CP116077 Location: 1..70464 Organism: Escherichia coli strain DETEC-S586 Replicon: plasmid pDETEC48
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PIC49_RS25040 () | 101..349 | + | 249 | WP_000083839.1 | replication regulatory protein RepA | - |
| PIC49_RS25045 () | 594..668 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| PIC49_RS25050 () | 661..1518 | + | 858 | WP_016240488.1 | incFII family plasmid replication initiator RepA | - |
| PIC49_RS25055 () | 2430..2699 | + | 270 | WP_000079935.1 | type II toxin-antitoxin system antitoxin YacA | Antitoxin Detail |
| PIC49_RS25060 () | 2699..2977 | + | 279 | WP_244493824.1 | type II toxin-antitoxin system toxin YacB | Toxin Detail |
| PIC49_RS25065 () | 3023..3871 | + | 849 | WP_001058003.1 | 3'-5' exonuclease | - |
| PIC49_RS25070 () | 3988..4470 | + | 483 | WP_001311056.1 | hypothetical protein | - |
| PIC49_RS25075 () | 4830..5946 | - | 1117 | Protein_7 | IS91 family transposase IS91 | Transposase |
| PIC49_RS25080 () | 5946..6311 | - | 366 | WP_000124093.1 | hypothetical protein | - |
| PIC49_RS25085 () | 6839..7348 | + | 510 | WP_000115002.1 | peptide deformylase | - |
| PIC49_RS25090 () | 7363..7464 | + | 102 | Protein_10 | methionyl-tRNA formyltransferase | - |
| PIC49_RS25095 () | 7661..7852 | + | 192 | WP_000175572.1 | DUF2164 family protein | - |
| PIC49_RS25100 () | 7849..8211 | + | 363 | WP_000181070.1 | DUF4440 domain-containing protein | - |
| PIC49_RS25105 () | 8545..9072 | - | 528 | WP_001196880.1 | DoxX family protein | - |
| PIC49_RS25110 () | 9074..9832 | - | 759 | WP_001181584.1 | DNA-binding domain-containing protein | - |
| PIC49_RS25115 () | 9801..10727 | - | 927 | WP_000989040.1 | DUF692 domain-containing protein | - |
| PIC49_RS25120 () | 10759..11049 | - | 291 | WP_000754126.1 | DUF2282 domain-containing protein | - |
| PIC49_RS25125 () | 11358..11915 | - | 558 | WP_000103553.1 | hypothetical protein | VF |
| PIC49_RS25130 () | 12562..13128 | + | 567 | WP_000587874.1 | hypothetical protein | - |
| PIC49_RS25135 () | 13196..13315 | - | 120 | Protein_19 | transposase domain-containing protein | - |
| PIC49_RS25140 () | 13517..14497 | + | 981 | WP_001218105.1 | plasmid segregation protein ParM | - |
| PIC49_RS25145 () | 14500..14922 | + | 423 | WP_000774834.1 | plasmid partitioning/stability family protein | - |
| PIC49_RS25150 () | 14946..15236 | + | 291 | WP_061092123.1 | hypothetical protein | - |
| PIC49_RS25155 () | 15346..16248 | + | 903 | WP_001464065.1 | DUF1281 domain-containing protein | - |
| PIC49_RS25160 () | 16245..16556 | + | 312 | WP_012680995.1 | hypothetical protein | - |
| PIC49_RS25165 () | 16632..17315 | + | 684 | WP_023485601.1 | DNA methylase | - |
| PIC49_RS25170 () | 17316..17537 | + | 222 | WP_001104892.1 | hypothetical protein | - |
| PIC49_RS25175 () | 17467..17985 | + | 519 | WP_240532625.1 | DUF1380 family protein | - |
| PIC49_RS25180 () | 18030..18800 | + | 771 | WP_023486083.1 | hypothetical protein | - |
| PIC49_RS25185 () | 19212..19637 | + | 426 | WP_001198882.1 | antirestriction protein | - |
| PIC49_RS25190 () | 19684..20106 | + | 423 | WP_001463949.1 | DUF1380 family protein | - |
| PIC49_RS25195 () | 20103..20294 | + | 192 | WP_001027499.1 | hypothetical protein | - |
| PIC49_RS25200 () | 20625..20779 | - | 155 | Protein_32 | hypothetical protein | - |
| PIC49_RS25205 () | 21294..21524 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| PIC49_RS25210 () | 21576..22937 | + | 1362 | WP_271293238.1 | DUF3560 domain-containing protein | - |
| PIC49_RS25215 () | 22984..23547 | + | 564 | WP_001297832.1 | class I SAM-dependent methyltransferase | - |
| PIC49_RS25220 () | 23633..24071 | - | 439 | Protein_36 | hypothetical protein | - |
| PIC49_RS25225 () | 24373..24900 | + | 528 | WP_128469085.1 | single-stranded DNA-binding protein | - |
| PIC49_RS25230 () | 24957..25190 | + | 234 | WP_000006003.1 | DUF905 family protein | - |
| PIC49_RS25235 () | 25251..27215 | + | 1965 | WP_000117316.1 | ParB/RepB/Spo0J family partition protein | - |
| PIC49_RS25240 () | 27284..27718 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| PIC49_RS25245 () | 27715..28477 | + | 763 | Protein_41 | plasmid SOS inhibition protein A | - |
| - () | 28446..28670 | + | 225 | NuclAT_0 | - | - |
| - () | 28446..28670 | + | 225 | NuclAT_0 | - | - |
| - () | 28446..28670 | + | 225 | NuclAT_0 | - | - |
| - () | 28446..28670 | + | 225 | NuclAT_0 | - | - |
| PIC49_RS25250 () | 28455..28634 | - | 180 | WP_001309233.1 | hypothetical protein | - |
| - | 28603..28668 | - | 66 | - | - | Antitoxin Detail |
| PIC49_RS25255 () | 28656..28805 | + | 150 | Protein_43 | plasmid maintenance protein Mok | - |
| PIC49_RS25260 () | 28747..28872 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| PIC49_RS25265 () | 29173..29469 | - | 297 | Protein_45 | hypothetical protein | - |
| PIC49_RS25270 () | 29769..30065 | + | 297 | WP_001272251.1 | hypothetical protein | - |
| PIC49_RS25275 () | 30176..30997 | + | 822 | WP_001234445.1 | DUF932 domain-containing protein | - |
| PIC49_RS25280 () | 31294..31884 | - | 591 | WP_000252683.1 | hypothetical protein | VF |
| PIC49_RS25285 () | 32217..32600 | + | 384 | WP_001151529.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| PIC49_RS25290 () | 32792..33439 | + | 648 | WP_000332523.1 | transcriptional regulator TraJ family protein | - |
| PIC49_RS25295 () | 33559..33786 | + | 228 | WP_000589556.1 | conjugal transfer relaxosome protein TraY | - |
| PIC49_RS25300 () | 33820..34182 | + | 363 | WP_012881131.1 | type IV conjugative transfer system pilin TraA | - |
| PIC49_RS25305 () | 34197..34508 | + | 312 | WP_000012100.1 | type IV conjugative transfer system protein TraL | - |
| PIC49_RS25310 () | 34530..35096 | + | 567 | WP_000399780.1 | type IV conjugative transfer system protein TraE | - |
| PIC49_RS25315 () | 35083..35811 | + | 729 | WP_001230769.1 | type-F conjugative transfer system secretin TraK | - |
| PIC49_RS25320 () | 35811..37238 | + | 1428 | WP_012881130.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| PIC49_RS25325 () | 37228..37818 | + | 591 | WP_012881129.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| PIC49_RS25330 () | 37805..38125 | + | 321 | WP_012881128.1 | conjugal transfer protein TrbD | - |
| PIC49_RS25335 () | 38122..38637 | + | 516 | WP_000809881.1 | type IV conjugative transfer system lipoprotein TraV | - |
| PIC49_RS25340 () | 38772..38993 | + | 222 | WP_001278683.1 | conjugal transfer protein TraR | - |
| PIC49_RS25345 () | 38986..39462 | + | 477 | WP_012881127.1 | hypothetical protein | - |
| PIC49_RS25350 () | 39561..39779 | + | 219 | WP_000556745.1 | hypothetical protein | - |
| PIC49_RS25355 () | 39807..40154 | + | 348 | WP_000836682.1 | hypothetical protein | - |
| PIC49_RS25360 () | 40280..42910 | + | 2631 | WP_000069772.1 | type IV secretion system protein TraC | - |
| PIC49_RS25365 () | 42907..43293 | + | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| PIC49_RS25370 () | 43290..43922 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| PIC49_RS25375 () | 43919..44911 | + | 993 | WP_000830849.1 | conjugal transfer pilus assembly protein TraU | - |
| PIC49_RS25380 () | 44941..45246 | + | 306 | WP_000224418.1 | hypothetical protein | - |
| PIC49_RS25385 () | 45255..45893 | + | 639 | WP_012881126.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| PIC49_RS25390 () | 45890..47740 | + | 1851 | WP_012881125.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| PIC49_RS25395 () | 47767..48024 | + | 258 | WP_000864353.1 | conjugal transfer protein TrbE | - |
| PIC49_RS25400 () | 48017..48760 | + | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| PIC49_RS25405 () | 48774..49115 | + | 342 | WP_000556795.1 | conjugal transfer protein TrbA | - |
| PIC49_RS25410 () | 49096..49431 | - | 336 | WP_000736414.1 | hypothetical protein | - |
| PIC49_RS25415 () | 49512..49796 | + | 285 | WP_000624107.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| PIC49_RS25420 () | 49783..50328 | + | 546 | WP_000059830.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| PIC49_RS25425 () | 50258..50605 | + | 348 | WP_011666494.1 | P-type conjugative transfer protein TrbJ | - |
| PIC49_RS25430 () | 50586..50978 | + | 393 | WP_000659962.1 | F-type conjugal transfer protein TrbF | - |
| PIC49_RS25435 () | 50965..52338 | + | 1374 | WP_000944331.1 | conjugal transfer pilus assembly protein TraH | - |
| PIC49_RS25440 () | 52335..55160 | + | 2826 | WP_012881124.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| PIC49_RS25445 () | 55157..55666 | + | 510 | WP_000628111.1 | conjugal transfer entry exclusion protein TraS | - |
| PIC49_RS25450 () | 55680..56411 | + | 732 | WP_012881123.1 | conjugal transfer complement resistance protein TraT | - |
| PIC49_RS25455 () | 56614..57351 | + | 738 | WP_012881122.1 | hypothetical protein | - |
| PIC49_RS25460 () | 57402..59708 | + | 2307 | WP_271293236.1 | Coupling protein TraD | VF |
| PIC49_RS25465 () | 59708..64978 | + | 5271 | WP_271293237.1 | Multifunctional conjugation protein TraI | Relaxase |
| PIC49_RS25470 () | 64998..65744 | + | 747 | WP_060578161.1 | conjugal transfer pilus acetylase TraX | - |
| PIC49_RS25475 () | 65803..66663 | + | 861 | WP_000704523.1 | Quorum-quenching protein AidA | VF |
| PIC49_RS25480 () | 66766..67326 | + | 561 | WP_000139321.1 | fertility inhibition protein FinO | - |
| PIC49_RS25485 () | 67455..67667 | + | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| PIC49_RS25490 () | 67912..68373 | + | 462 | WP_001233838.1 | thermonuclease family protein | - |
| PIC49_RS25495 () | 68419..68628 | + | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| PIC49_RS25500 () | 68666..69256 | + | 591 | WP_033807967.1 | DUF2726 domain-containing protein | - |
| PIC49_RS25505 () | 69411..69884 | + | 474 | WP_016240489.1 | hypothetical protein | - |
| - () | 70027..70086 | - | 60 | NuclAT_1 | - | - |
| - () | 70027..70086 | - | 60 | NuclAT_1 | - | - |
| - () | 70027..70086 | - | 60 | NuclAT_1 | - | - |
| - () | 70027..70086 | - | 60 | NuclAT_1 | - | - |
| PIC49_RS25510 () | 70131..70280 | + | 150 | WP_001312851.1 | Hok/Gef family protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|