Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | parDE/RelE-RHH |
| Location | 2430..2977 | Replicon | plasmid pDETEC48 |
| Accession | NZ_CP116077 | ||
| Organism | Escherichia coli strain DETEC-S586 | ||
Toxin (Protein)
| Gene name | parE | Uniprot ID | - |
| Locus tag | PIC49_RS25060 | Protein ID | WP_244493824.1 |
| Coordinates | 2699..2977 (+) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | parD | Uniprot ID | A0A6G9U792 |
| Locus tag | PIC49_RS25055 | Protein ID | WP_000079935.1 |
| Coordinates | 2430..2699 (+) | Length | 90 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PIC49_RS25040 (101) | 101..349 | + | 249 | WP_000083839.1 | replication regulatory protein RepA | - |
| PIC49_RS25045 (594) | 594..668 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| PIC49_RS25050 (661) | 661..1518 | + | 858 | WP_016240488.1 | incFII family plasmid replication initiator RepA | - |
| PIC49_RS25055 (2430) | 2430..2699 | + | 270 | WP_000079935.1 | type II toxin-antitoxin system antitoxin YacA | Antitoxin |
| PIC49_RS25060 (2699) | 2699..2977 | + | 279 | WP_244493824.1 | type II toxin-antitoxin system toxin YacB | Toxin |
| PIC49_RS25065 (3023) | 3023..3871 | + | 849 | WP_001058003.1 | 3'-5' exonuclease | - |
| PIC49_RS25070 (3988) | 3988..4470 | + | 483 | WP_001311056.1 | hypothetical protein | - |
| PIC49_RS25075 (4830) | 4830..5946 | - | 1117 | Protein_7 | IS91 family transposase | - |
| PIC49_RS25080 (5946) | 5946..6311 | - | 366 | WP_000124093.1 | hypothetical protein | - |
| PIC49_RS25085 (6839) | 6839..7348 | + | 510 | WP_000115002.1 | peptide deformylase | - |
| PIC49_RS25090 (7363) | 7363..7464 | + | 102 | Protein_10 | methionyl-tRNA formyltransferase | - |
| PIC49_RS25095 (7661) | 7661..7852 | + | 192 | WP_000175572.1 | DUF2164 family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Conjugative plasmid | - | - | 1..70464 | 70464 | |
| - | flank | IS/Tn | - | - | 4861..5583 | 722 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|