MGE detailed information
MGE type: Conjugative plasmid MGE length: 126200 bp
Accession: NZ_CP109876 Location: 1..126200 Organism: Escherichia coli strain EC488 Replicon: plasmid pEC488-KPC-2
Accession: NZ_CP109876 Location: 1..126200 Organism: Escherichia coli strain EC488 Replicon: plasmid pEC488-KPC-2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NQ150_RS25840 (46) | 46..1077 | + | 1032 | WP_000907852.1 | plasmid replication initiator RepA | - |
| NQ150_RS25845 (1981) | 1981..2265 | + | 285 | WP_001178087.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| NQ150_RS25850 (2265) | 2265..2540 | + | 276 | WP_000421259.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| NQ150_RS25855 (2646) | 2646..2849 | + | 204 | Protein_3 | hypothetical protein | - |
| NQ150_RS25860 (3119) | 3119..3385 | - | 267 | WP_000627832.1 | hypothetical protein | - |
| NQ150_RS25865 (3385) | 3385..3879 | - | 495 | WP_015058884.1 | hypothetical protein | - |
| NQ150_RS25870 (3935) | 3935..4537 | - | 603 | WP_000521606.1 | ProQ/FINO family protein | - |
| NQ150_RS25875 (4713) | 4713..5765 | - | 1053 | WP_000655519.1 | hypothetical protein | - |
| NQ150_RS25880 (5978) | 5978..6568 | - | 591 | WP_001401589.1 | hypothetical protein | - |
| NQ150_RS25885 (6568) | 6568..6822 | - | 255 | WP_000343106.1 | hypothetical protein | - |
| NQ150_RS25890 (7391) | 7391..7804 | + | 414 | WP_052968875.1 | hypothetical protein | - |
| NQ150_RS25895 (7806) | 7806..8585 | + | 780 | WP_052971527.1 | site-specific integrase | - |
| NQ150_RS25900 (8765) | 8765..9409 | + | 645 | WP_001144036.1 | ParA family protein | - |
| NQ150_RS25905 (9496) | 9496..9804 | + | 309 | WP_000030199.1 | hypothetical protein | - |
| NQ150_RS25910 (10218) | 10218..11198 | + | 981 | WP_000688519.1 | plasmid segregation protein ParM | - |
| NQ150_RS25915 (11191) | 11191..11607 | + | 417 | WP_001278818.1 | plasmid partitioning/stability family protein | - |
| NQ150_RS25920 (11609) | 11609..12883 | - | 1275 | WP_000457524.1 | Y-family DNA polymerase | - |
| NQ150_RS25925 (12883) | 12883..13320 | - | 438 | WP_000109071.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| NQ150_RS25930 (13317) | 13317..13565 | - | 249 | WP_000618110.1 | DinI-like family protein | - |
| NQ150_RS25935 (13983) | 13983..14885 | + | 903 | WP_148999501.1 | DUF1281 domain-containing protein | - |
| NQ150_RS25940 (14882) | 14882..15193 | + | 312 | WP_032317461.1 | hypothetical protein | - |
| NQ150_RS25945 (15269) | 15269..15952 | + | 684 | WP_000086185.1 | DNA methylase | - |
| NQ150_RS25950 (15953) | 15953..16174 | + | 222 | WP_001104879.1 | hypothetical protein | - |
| NQ150_RS25955 (16155) | 16155..16622 | + | 468 | WP_247173462.1 | DUF1380 family protein | - |
| NQ150_RS25960 (16667) | 16667..17437 | + | 771 | WP_023156301.1 | hypothetical protein | - |
| NQ150_RS25965 (17849) | 17849..18274 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| NQ150_RS25970 (18321) | 18321..18743 | + | 423 | WP_000271744.1 | DUF1380 family protein | - |
| NQ150_RS25975 (18740) | 18740..18931 | + | 192 | WP_001027495.1 | hypothetical protein | - |
| NQ150_RS25980 (19003) | 19003..19317 | + | 315 | WP_001434357.1 | hypothetical protein | - |
| NQ150_RS25985 (19701) | 19701..20228 | + | 528 | WP_001276120.1 | single-stranded DNA-binding protein | - |
| NQ150_RS25990 (20286) | 20286..20519 | + | 234 | WP_176704383.1 | DUF905 domain-containing protein | - |
| NQ150_RS25995 (20578) | 20578..22536 | + | 1959 | WP_264403817.1 | ParB/RepB/Spo0J family partition protein | - |
| NQ150_RS26000 (22591) | 22591..23025 | + | 435 | WP_000845897.1 | conjugation system SOS inhibitor PsiB | - |
| NQ150_RS26005 (23022) | 23022..23741 | + | 720 | WP_001276261.1 | plasmid SOS inhibition protein A | - |
| NQ150_RS26010 (23738) | 23738..24334 | + | 597 | WP_000978012.1 | hypothetical protein | - |
| NQ150_RS26015 (24797) | 24797..25297 | + | 501 | WP_000117622.1 | antirestriction protein ArdA | - |
| NQ150_RS26020 (26026) | 26026..26460 | + | 435 | WP_000218863.1 | hypothetical protein | - |
| NQ150_RS26025 (26553) | 26553..26819 | + | 267 | WP_001247862.1 | hypothetical protein | - |
| NQ150_RS26030 (26884) | 26884..27774 | + | 891 | WP_261630081.1 | ISNCY family transposase ISSen7 | VF |
| NQ150_RS26035 (27837) | 27837..28031 | + | 195 | WP_001496986.1 | hypothetical protein | - |
| NQ150_RS26040 (28062) | 28062..28313 | - | 252 | WP_000148286.1 | helix-turn-helix transcriptional regulator | - |
| NQ150_RS26045 (28894) | 28894..29742 | + | 849 | WP_021513954.1 | DUF4942 domain-containing protein | - |
| NQ150_RS26050 (29828) | 29828..30163 | - | 336 | WP_000157095.1 | molybdopterin-guanine dinucleotide biosynthesis protein MobC | - |
| NQ150_RS26055 (30397) | 30397..30729 | + | 333 | WP_001283947.1 | IncI1-type relaxosome accessory protein NikA | - |
| NQ150_RS26060 (30740) | 30740..33439 | + | 2700 | WP_052971501.1 | hypothetical protein | Relaxase |
| NQ150_RS26065 (33476) | 33476..35767 | - | 2292 | WP_261630080.1 | F-type conjugative transfer protein TrbC | - |
| NQ150_RS26070 (35760) | 35760..36830 | - | 1071 | WP_000151583.1 | IncI1-type conjugal transfer protein TrbB | - |
| NQ150_RS26075 (36849) | 36849..38057 | - | 1209 | WP_001303305.1 | IncI1-type conjugal transfer protein TrbA | - |
| NQ150_RS26080 (38364) | 38364..39449 | - | 1086 | WP_000080543.1 | protein finQ | - |
| - (39658) | 39658..39718 | - | 61 | NuclAT_0 | - | Antitoxin Detail |
| - (39658) | 39658..39718 | - | 61 | NuclAT_0 | - | Antitoxin Detail |
| - (39658) | 39658..39718 | - | 61 | NuclAT_0 | - | Antitoxin Detail |
| - (39658) | 39658..39718 | - | 61 | NuclAT_0 | - | Antitoxin Detail |
| NQ150_RS26085 (39770) | 39770..39922 | + | 153 | WP_001387489.1 | Hok/Gef family protein | Toxin Detail |
| NQ150_RS26090 (39975) | 39975..40244 | - | 270 | WP_261630079.1 | hypothetical protein | - |
| NQ150_RS26095 (40544) | 40544..40840 | + | 297 | WP_011264046.1 | DinQ-like type I toxin DqlB | - |
| NQ150_RS26100 (40905) | 40905..41081 | - | 177 | WP_001054897.1 | hypothetical protein | - |
| NQ150_RS26105 (41473) | 41473..41682 | + | 210 | WP_000062602.1 | HEAT repeat domain-containing protein | - |
| NQ150_RS26110 (41754) | 41754..42416 | - | 663 | WP_000644797.1 | plasmid IncI1-type surface exclusion protein ExcA | - |
| NQ150_RS26115 (42487) | 42487..44655 | - | 2169 | WP_015508354.1 | DotA/TraY family protein | - |
| NQ150_RS26120 (44752) | 44752..45336 | - | 585 | WP_261630078.1 | IncI1-type conjugal transfer protein TraX | - |
| NQ150_RS26125 (45365) | 45365..46567 | - | 1203 | WP_001189160.1 | IncI1-type conjugal transfer protein TraW | - |
| NQ150_RS26130 (46534) | 46534..47148 | - | 615 | WP_000337398.1 | IncI1-type conjugal transfer protein TraV | - |
| NQ150_RS26135 (47148) | 47148..50192 | - | 3045 | WP_001024776.1 | IncI1-type conjugal transfer protein TraU | - |
| NQ150_RS26140 (50282) | 50282..51082 | - | 801 | WP_001164792.1 | IncI1-type conjugal transfer protein TraT | - |
| NQ150_RS26145 (51066) | 51066..51254 | - | 189 | WP_001277255.1 | putative conjugal transfer protein TraS | - |
| NQ150_RS26150 (51318) | 51318..51722 | - | 405 | WP_000086960.1 | IncI1-type conjugal transfer protein TraR | - |
| NQ150_RS26155 (51773) | 51773..52300 | - | 528 | WP_001055569.1 | conjugal transfer protein TraQ | - |
| NQ150_RS26160 (52300) | 52300..53004 | - | 705 | WP_261630077.1 | IncI1-type conjugal transfer protein TraP | - |
| NQ150_RS26165 (53004) | 53004..54293 | - | 1290 | WP_001271994.1 | conjugal transfer protein TraO | - |
| NQ150_RS26170 (54296) | 54296..55279 | - | 984 | WP_021513963.1 | hypothetical protein | VF |
| NQ150_RS26175 (55290) | 55290..55982 | - | 693 | WP_000138552.1 | DotI/IcmL family type IV secretion protein | - |
| NQ150_RS26180 (55979) | 55979..56326 | - | 348 | WP_001055900.1 | conjugal transfer protein | - |
| NQ150_RS26185 (56344) | 56344..60111 | - | 3768 | WP_006855639.1 | DUF5710 domain-containing protein | - |
| NQ150_RS26190 (60201) | 60201..60752 | - | 552 | WP_000014584.1 | Phospholipase D | VF |
| NQ150_RS26195 (60767) | 60767..61057 | - | 291 | WP_001299214.1 | hypothetical protein | - |
| NQ150_RS26200 (61054) | 61054..62202 | - | 1149 | WP_001024976.1 | putative protein YggR | VF |
| NQ150_RS26205 (62199) | 62199..63017 | - | 819 | WP_000646097.1 | hypothetical protein | VF |
| NQ150_RS26210 (63014) | 63014..63472 | - | 459 | WP_001079808.1 | hypothetical protein | VF |
| NQ150_RS26215 (63867) | 63867..64451 | - | 585 | WP_000977520.1 | histidine phosphatase family protein | - |
| NQ150_RS26220 (64511) | 64511..65713 | - | 1203 | WP_000976357.1 | conjugal transfer protein TraF | - |
| NQ150_RS26225 (65799) | 65799..66623 | - | 825 | WP_015058912.1 | conjugal transfer protein TraE | - |
| NQ150_RS26230 (66774) | 66774..67928 | - | 1155 | WP_001139955.1 | site-specific integrase | - |
| NQ150_RS26235 (69124) | 69124..70509 | - | 1386 | WP_264403765.1 | IS66 family transposase ISEc8 | Transposase |
| NQ150_RS26240 (70559) | 70559..70906 | - | 348 | WP_000612591.1 | IS66 family transposase ISEc8 | Transposase |
| NQ150_RS26245 (70903) | 70903..71283 | - | 381 | WP_001171554.1 | IS66 family transposase ISEc8 | Transposase |
| NQ150_RS26250 (71359) | 71359..71502 | - | 144 | WP_261630128.1 | hypothetical protein | - |
| NQ150_RS26255 (71745) | 71745..71993 | + | 249 | WP_001349157.1 | hypothetical protein | - |
| NQ150_RS26260 (71990) | 71990..73282 | - | 1293 | WP_039719938.1 | hypothetical protein | VF |
| NQ150_RS26265 (73282) | 73282..73938 | - | 657 | WP_001193551.1 | hypothetical protein | VF |
| NQ150_RS26270 (73923) | 73923..74483 | - | 561 | WP_000014005.1 | hypothetical protein | VF |
| NQ150_RS26275 (74493) | 74493..75107 | - | 615 | WP_000908228.1 | hypothetical protein | VF |
| NQ150_RS26280 (75124) | 75124..76209 | - | 1086 | WP_001208803.1 | hypothetical protein | VF |
| NQ150_RS26285 (76222) | 76222..77775 | - | 1554 | WP_000362204.1 | hypothetical protein | VF |
| NQ150_RS26290 (77786) | 77786..78238 | - | 453 | WP_001247333.1 | hypothetical protein | VF |
| NQ150_RS26295 (78225) | 78225..79520 | - | 1296 | WP_137460884.1 | type 4b pilus protein PilO2 | - |
| NQ150_RS26300 (79513) | 79513..81195 | - | 1683 | WP_000748143.1 | hypothetical protein | VF |
| NQ150_RS26305 (81209) | 81209..81646 | - | 438 | WP_000539811.1 | hypothetical protein | VF |
| NQ150_RS26310 (81646) | 81646..82713 | - | 1068 | WP_021513968.1 | hypothetical protein | VF |
| NQ150_RS26315 (83465) | 83465..83719 | - | 255 | WP_001136187.1 | PilI type IV pilus biogenesis protein | - |
| NQ150_RS26320 (83891) | 83891..84574 | - | 684 | WP_000213863.1 | hypothetical protein | - |
| NQ150_RS26325 (84828) | 84828..85361 | - | 534 | WP_001372168.1 | transcription termination/antitermination NusG family protein | - |
| NQ150_RS26330 (85803) | 85803..86090 | - | 288 | WP_000074849.1 | conjugal transfer protein TraA | - |
| NQ150_RS26335 (86008) | 86008..86238 | - | 231 | WP_228772074.1 | ash family protein | - |
| NQ150_RS26340 (86483) | 86483..87187 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| NQ150_RS26345 (87234) | 87234..87368 | + | 135 | Protein_101 | transposase | - |
| NQ150_RS26350 (87420) | 87420..87881 | + | 462 | Protein_102 | Tn3 family transposase TnpR_Tn3 | Transposase |
| NQ150_RS26355 (88004) | 88004..88984 | + | 981 | WP_013213985.1 | IS481 family transposase ISKpn27 | Transposase |
| NQ150_RS26360 (89260) | 89260..90141 | + | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| NQ150_RS26365 (90391) | 90391..90783 | - | 393 | Protein_105 | IS1182 family transposase ISKpn6 | Transposase |
| NQ150_RS26370 (90833) | 90833..91537 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| NQ150_RS26375 (91703) | 91703..91951 | + | 249 | WP_032734746.1 | hypothetical protein | - |
| NQ150_RS26380 (92181) | 92181..92651 | - | 471 | WP_140026880.1 | conjugal transfer protein TraB | - |
| NQ150_RS26385 (92703) | 92703..94166 | - | 1464 | WP_140026881.1 | hypothetical protein | VF |
| NQ150_RS26390 (94163) | 94163..94621 | - | 459 | WP_032734695.1 | conjugal transfer protein TrbH | - |
| NQ150_RS26395 (94623) | 94623..95543 | - | 921 | WP_205955143.1 | P-type conjugative transfer protein TrbG | - |
| NQ150_RS26400 (95561) | 95561..96259 | - | 699 | WP_004167166.1 | type IV secretion system protein | - |
| NQ150_RS26405 (96349) | 96349..96654 | - | 306 | WP_034047586.1 | hypothetical protein | - |
| NQ150_RS26410 (96658) | 96658..98376 | - | 1719 | WP_117247869.1 | P-type conjugative transfer protein TrbL | - |
| NQ150_RS26415 (98380) | 98380..98583 | - | 204 | WP_004167247.1 | hypothetical protein | - |
| NQ150_RS26420 (98584) | 98584..99372 | - | 789 | WP_140026882.1 | P-type conjugative transfer protein TrbJ | - |
| NQ150_RS26425 (99341) | 99341..101848 | - | 2508 | WP_021155427.1 | hypothetical protein | - |
| NQ150_RS26430 (101862) | 101862..102167 | - | 306 | WP_032440821.1 | conjugal transfer protein TrbD | - |
| NQ150_RS26435 (102176) | 102176..102667 | - | 492 | WP_021155429.1 | TrbC/VirB2 family protein | - |
| NQ150_RS26440 (102679) | 102679..103662 | - | 984 | WP_061456087.1 | Type IV secretion system protein VirB11 | VF |
| NQ150_RS26445 (103843) | 103843..104103 | - | 261 | WP_004167234.1 | helix-turn-helix transcriptional regulator | - |
| NQ150_RS26450 (104261) | 104261..105502 | + | 1242 | WP_140026883.1 | replication initiator protein A | - |
| NQ150_RS26455 (106000) | 106000..106443 | - | 444 | WP_032734707.1 | hypothetical protein | - |
| NQ150_RS26460 (106879) | 106879..107205 | + | 327 | WP_004167231.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| NQ150_RS26465 (107209) | 107209..107520 | + | 312 | WP_004167230.1 | hypothetical protein | - |
| NQ150_RS26470 (107617) | 107617..107907 | - | 291 | WP_032734711.1 | hypothetical protein | - |
| NQ150_RS26475 (107912) | 107912..108280 | - | 369 | WP_032734713.1 | hypothetical protein | - |
| NQ150_RS26480 (108306) | 108306..108665 | - | 360 | WP_140026884.1 | hypothetical protein | - |
| NQ150_RS26485 (108713) | 108713..109168 | - | 456 | WP_021155439.1 | hypothetical protein | - |
| NQ150_RS26490 (109180) | 109180..109935 | - | 756 | WP_021155400.1 | transfer origin protein, TraL | - |
| NQ150_RS26495 (109952) | 109952..110335 | - | 384 | WP_004167204.1 | TraK family protein | - |
| NQ150_RS26500 (110733) | 110733..111101 | + | 369 | WP_004167202.1 | CopG family transcriptional regulator | - |
| NQ150_RS26505 (111098) | 111098..113071 | + | 1974 | Protein_133 | hypothetical protein | Relaxase |
| NQ150_RS26510 (113791) | 113791..115749 | + | 1959 | WP_140026886.1 | Conjugal transfer protein TraG | VF |
| NQ150_RS26515 (115746) | 115746..116312 | + | 567 | WP_140026887.1 | S26 family signal peptidase | - |
| NQ150_RS26520 (116309) | 116309..117298 | + | 990 | WP_247886293.1 | hypothetical protein | VF |
| NQ150_RS26525 (117301) | 117301..120912 | + | 3612 | WP_210268956.1 | zincin-like metallopeptidase domain-containing protein | - |
| NQ150_RS26530 (120970) | 120970..122623 | + | 1654 | Protein_138 | DNA topoisomerase | - |
| NQ150_RS26535 (122910) | 122910..123617 | + | 708 | WP_140026888.1 | fertility inhibition factor FiwA | - |
| NQ150_RS26540 (123885) | 123885..124340 | - | 456 | WP_032734735.1 | hypothetical protein | - |
| NQ150_RS26545 (124401) | 124401..124598 | - | 198 | WP_261630085.1 | hypothetical protein | - |
| NQ150_RS26550 (124657) | 124657..125361 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|