MGE detailed information
MGE type: Mobilizable plasmid MGE length: 163762 bp
Accession: NZ_CP104527 Location: 1..163762 Organism: Escherichia coli strain E8 Replicon: plasmid p1
Accession: NZ_CP104527 Location: 1..163762 Organism: Escherichia coli strain E8 Replicon: plasmid p1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| N5O73_RS23210 (N5O73_23215) | 1..882 | + | 882 | WP_032206658.1 | RepB family plasmid replication initiator protein | - |
| N5O73_RS23215 (N5O73_23220) | 1657..1965 | - | 309 | WP_050010471.1 | hypothetical protein | - |
| N5O73_RS23220 (N5O73_23225) | 2020..3081 | - | 1062 | Protein_2 | IS30 family transposase IS30D | Transposase |
| N5O73_RS23225 (N5O73_23230) | 3196..3384 | + | 189 | WP_000957857.1 | hypothetical protein | - |
| N5O73_RS23230 (N5O73_23235) | 3394..4593 | + | 1200 | WP_000948429.1 | IS91 family transposase ISSbo1 | Transposase |
| N5O73_RS23235 (N5O73_23240) | 4783..5019 | + | 237 | WP_001648123.1 | hypothetical protein | - |
| N5O73_RS23240 (N5O73_23245) | 5054..5185 | + | 132 | WP_001113883.1 | hypothetical protein | - |
| N5O73_RS23245 (N5O73_23250) | 5195..5587 | + | 393 | WP_001281115.1 | hypothetical protein | - |
| N5O73_RS23250 (N5O73_23255) | 5923..6807 | + | 885 | WP_001113742.1 | RepB family plasmid replication initiator protein | - |
| N5O73_RS23255 (N5O73_23260) | 7100..7909 | + | 810 | WP_001154687.1 | GIY-YIG nuclease family protein | - |
| N5O73_RS23260 (N5O73_23265) | 8078..9274 | + | 1197 | WP_001285362.1 | AAA family ATPase | - |
| N5O73_RS23265 (N5O73_23270) | 9291..10292 | + | 1002 | WP_000038866.1 | ParB family protein | - |
| N5O73_RS23270 (N5O73_23275) | 10518..12224 | + | 1707 | WP_181030078.1 | hypothetical protein | - |
| N5O73_RS23275 (N5O73_23280) | 12284..13873 | + | 1590 | WP_261246523.1 | hypothetical protein | - |
| N5O73_RS23280 (N5O73_23285) | 13883..14698 | + | 816 | WP_032277755.1 | hypothetical protein | - |
| N5O73_RS23285 (N5O73_23290) | 14851..15315 | + | 465 | WP_001361637.1 | hypothetical protein | - |
| N5O73_RS23290 (N5O73_23295) | 15327..15836 | + | 510 | WP_000509940.1 | hypothetical protein | - |
| N5O73_RS23295 (N5O73_23300) | 16112..17224 | - | 1113 | WP_001300563.1 | IS4 family transposase IS421 | Transposase |
| N5O73_RS23300 (N5O73_23305) | 17302..17457 | - | 156 | WP_001352007.1 | type I toxin-antitoxin system toxin HokD | - |
| N5O73_RS23305 (N5O73_23310) | 17775..18947 | + | 1173 | WP_261246524.1 | IS21 family transposase IS21 | Transposase |
| N5O73_RS23310 (N5O73_23315) | 18947..19744 | + | 798 | WP_064186714.1 | IS21 family transposase IS21 | Transposase |
| N5O73_RS23315 (N5O73_23320) | 19989..20234 | + | 246 | Protein_21 | IS3 family transposase ISEhe3 | Transposase |
| N5O73_RS23320 (N5O73_23325) | 20247..21398 | - | 1152 | WP_061351745.1 | IS30 family transposase IS30D | Transposase |
| N5O73_RS23325 (N5O73_23330) | 21466..22348 | + | 883 | Protein_23 | IS3 family transposase ISEhe3 | Transposase |
| N5O73_RS23330 (N5O73_23335) | 24205..24902 | + | 698 | WP_095033700.1 | IS1-like element IS1B family transposase | - |
| N5O73_RS23335 (N5O73_23340) | 24917..25165 | - | 249 | Protein_25 | AraC family transcriptional regulator | - |
| N5O73_RS23340 (N5O73_23345) | 25460..26428 | + | 969 | WP_261246526.1 | IS5 family transposase IS903B | Transposase |
| N5O73_RS23345 (N5O73_23350) | 26691..27919 | + | 1229 | WP_261246527.1 | IS3 family transposase IS2 | Transposase |
| N5O73_RS23350 (N5O73_23355) | 27890..29359 | - | 1470 | WP_244587527.1 | hypothetical protein | Relaxase |
| N5O73_RS23355 (N5O73_23360) | 29409..30092 | - | 684 | WP_261246533.1 | hypothetical protein | - |
| N5O73_RS23360 (N5O73_23365) | 30089..30574 | - | 486 | WP_097489440.1 | conjugative transfer protein MobI(A/C) | - |
| N5O73_RS23365 (N5O73_23370) | 31601..32131 | + | 531 | WP_064186851.1 | hypothetical protein | - |
| N5O73_RS23370 (N5O73_23375) | 32134..32646 | + | 513 | WP_064186852.1 | hypothetical protein | - |
| N5O73_RS23375 (N5O73_23380) | 33208..33905 | + | 698 | WP_225321517.1 | IS1 family transposase IS1G | Transposase |
| N5O73_RS23380 (N5O73_23385) | 33989..34174 | - | 186 | WP_000066585.1 | hypothetical protein | - |
| N5O73_RS23385 (N5O73_23390) | 34273..34416 | - | 144 | Protein_35 | HNH endonuclease | - |
| N5O73_RS23395 (N5O73_23400) | 35282..35863 | + | 582 | WP_261246555.1 | aromatic amino acid transport family protein | - |
| N5O73_RS23400 (N5O73_23405) | 36334..37887 | - | 1554 | WP_261246535.1 | L-lactate permease | - |
| N5O73_RS23405 (N5O73_23410) | 38331..39476 | + | 1146 | Protein_39 | D-lactate dehydrogenase | - |
| N5O73_RS23410 (N5O73_23415) | 39687..40406 | + | 720 | WP_064186363.1 | (Fe-S)-binding protein | - |
| N5O73_RS23415 (N5O73_23420) | 40417..41844 | + | 1428 | WP_064186364.1 | LutB/LldF family L-lactate oxidation iron-sulfur protein | - |
| N5O73_RS23420 (N5O73_23425) | 41837..42532 | + | 696 | WP_064186365.1 | lactate utilization protein C | - |
| N5O73_RS23430 (N5O73_23435) | 43563..43772 | - | 210 | Protein_44 | putative isomerase YddE | VF |
| N5O73_RS23435 (N5O73_23440) | 43851..44531 | - | 681 | WP_000617116.1 | respiratory nitrate reductase subunit gamma | - |
| N5O73_RS23440 (N5O73_23445) | 44528..45223 | - | 696 | WP_160384839.1 | nitrate reductase molybdenum cofactor assembly chaperone | - |
| N5O73_RS23445 (N5O73_23450) | 45223..46767 | - | 1545 | WP_000702551.1 | nitrate reductase subunit beta | - |
| N5O73_RS23450 (N5O73_23455) | 46764..50504 | - | 3741 | WP_097489431.1 | nitrate reductase Z subunit alpha | - |
| N5O73_RS23455 (N5O73_23460) | 50599..51987 | - | 1389 | WP_065898688.1 | nitrate/nitrite transporter NarU | - |
| N5O73_RS23460 (N5O73_23465) | 52250..53230 | + | 981 | WP_000019445.1 | IS5 family transposase ISKpn26 | Transposase |
| N5O73_RS23465 (N5O73_23470) | 53378..53659 | - | 282 | WP_000220560.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| N5O73_RS23470 (N5O73_23475) | 53649..53900 | - | 252 | WP_000121743.1 | plasmid stabilization protein | Antitoxin Detail |
| N5O73_RS23475 (N5O73_23480) | 55049..56017 | + | 969 | WP_152946993.1 | IS5 family transposase IS903B | Transposase |
| N5O73_RS23480 (N5O73_23485) | 56177..56320 | + | 144 | WP_152930453.1 | hypothetical protein | - |
| N5O73_RS23485 (N5O73_23490) | 56381..56626 | + | 246 | Protein_55 | IS3 family transposase ISEhe3 | Transposase |
| N5O73_RS23490 (N5O73_23495) | 56694..57845 | + | 1152 | WP_152931003.1 | IS30 family transposase IS30D | Transposase |
| N5O73_RS23495 (N5O73_23500) | 57853..58115 | - | 263 | Protein_57 | IS3 family transposase ISEc52 | Transposase |
| N5O73_RS23500 (N5O73_23505) | 58190..58501 | + | 312 | Protein_58 | VRR-NUC domain-containing protein | - |
| N5O73_RS23505 (N5O73_23510) | 58568..58723 | + | 156 | WP_032236586.1 | hypothetical protein | - |
| N5O73_RS23510 (N5O73_23515) | 59028..59996 | + | 969 | WP_000654811.1 | IS5 family transposase IS903B | Transposase |
| N5O73_RS23515 (N5O73_23520) | 60290..60916 | + | 627 | WP_261246539.1 | hypothetical protein | - |
| N5O73_RS23520 (N5O73_23525) | 60913..61590 | + | 678 | Protein_62 | metallophosphoesterase | - |
| N5O73_RS23525 (N5O73_23530) | 61587..62288 | + | 702 | WP_059039678.1 | hypothetical protein | - |
| N5O73_RS23530 (N5O73_23535) | 62590..63832 | + | 1243 | Protein_64 | hypothetical protein | - |
| N5O73_RS23535 (N5O73_23540) | 63905..64411 | + | 507 | WP_000021755.1 | hypothetical protein | - |
| N5O73_RS23540 (N5O73_23545) | 64676..64969 | - | 294 | WP_261246557.1 | hypothetical protein | - |
| N5O73_RS23545 (N5O73_23550) | 65068..66276 | + | 1209 | WP_001339197.1 | IS4 family transposase IS10R | Transposase |
| N5O73_RS23550 (N5O73_23555) | 66290..69130 | - | 2841 | Protein_68 | HsdR family type I site-specific deoxyribonuclease | - |
| N5O73_RS23555 (N5O73_23560) | 69252..70379 | - | 1128 | WP_097489420.1 | restriction endonuclease subunit S | - |
| N5O73_RS23560 (N5O73_23565) | 70376..71932 | - | 1557 | WP_097489423.1 | type I restriction-modification system subunit M | - |
| N5O73_RS23565 (N5O73_23570) | 72115..72336 | + | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| N5O73_RS23570 (N5O73_23575) | 72336..72716 | + | 381 | WP_072731915.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| N5O73_RS23575 (N5O73_23580) | 72721..72900 | + | 180 | WP_089619425.1 | PdcA protein | - |
| N5O73_RS23580 (N5O73_23585) | 72928..73971 | + | 1044 | WP_033551394.1 | DUF968 domain-containing protein | - |
| N5O73_RS23585 (N5O73_23590) | 74060..74338 | + | 279 | WP_097489418.1 | hypothetical protein | - |
| N5O73_RS23590 (N5O73_23595) | 74626..75818 | + | 1193 | Protein_76 | terminase | - |
| N5O73_RS23595 (N5O73_23600) | 75818..77302 | + | 1485 | WP_223663934.1 | terminase | - |
| N5O73_RS23600 (N5O73_23605) | 77356..77688 | + | 333 | WP_224205061.1 | phage antirepressor KilAC domain-containing protein | - |
| N5O73_RS23605 (N5O73_23610) | 77721..78572 | - | 852 | WP_000611664.1 | phage repressor protein C1 | - |
| N5O73_RS23610 (N5O73_23615) | 78683..78892 | - | 210 | WP_000874156.1 | hypothetical protein | - |
| N5O73_RS23615 (N5O73_23620) | 79080..80060 | + | 981 | WP_123906188.1 | IS5 family transposase ISKpn26 | Transposase |
| N5O73_RS23625 (N5O73_23630) | 81190..83625 | + | 2436 | WP_061424402.1 | molybdopterin-dependent oxidoreductase | - |
| N5O73_RS23630 (N5O73_23635) | 83639..84265 | + | 627 | WP_000816147.1 | dimethylsulfoxide reductase subunit B | - |
| N5O73_RS23635 (N5O73_23640) | 84258..85034 | + | 777 | WP_000544912.1 | dimethyl sulfoxide reductase anchor subunit | - |
| N5O73_RS23640 (N5O73_23645) | 85089..85685 | + | 597 | WP_001139856.1 | Tat proofreading chaperone DmsD | - |
| N5O73_RS23645 (N5O73_23650) | 85715..86212 | + | 498 | WP_000019701.1 | 4Fe-4S binding protein | - |
| N5O73_RS23650 (N5O73_23655) | 86427..87407 | + | 981 | WP_123906188.1 | IS5 family transposase ISKpn26 | Transposase |
| N5O73_RS23655 (N5O73_23660) | 88044..88265 | + | 222 | WP_000542336.1 | hypothetical protein | - |
| N5O73_RS23660 (N5O73_23665) | 88273..89304 | + | 1032 | WP_000067536.1 | site-specific integrase | - |
| N5O73_RS23665 (N5O73_23670) | 89355..89666 | + | 312 | WP_001224235.1 | hypothetical protein | - |
| N5O73_RS23670 (N5O73_23675) | 89914..90189 | + | 276 | Protein_92 | recombinase | - |
| N5O73_RS23675 (N5O73_23680) | 90376..91827 | - | 1452 | WP_261246511.1 | hypothetical protein | VF |
| N5O73_RS23680 (N5O73_23685) | 91886..92590 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| N5O73_RS23685 (N5O73_23690) | 92683..93057 | - | 375 | WP_001348195.1 | cupin domain-containing protein | - |
| N5O73_RS23690 (N5O73_23695) | 93247..93683 | - | 437 | Protein_96 | IS66 family transposase ISPpu13 | Transposase |
| N5O73_RS23695 (N5O73_23700) | 93976..94263 | + | 288 | WP_009486461.1 | thermonuclease family protein | - |
| N5O73_RS23700 (N5O73_23705) | 94879..95112 | - | 234 | WP_000624775.1 | hypothetical protein | - |
| N5O73_RS23705 (N5O73_23710) | 95137..95841 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| N5O73_RS23710 (N5O73_23715) | 95895..96032 | - | 138 | Protein_100 | chemotaxis protein | - |
| N5O73_RS23715 (N5O73_23720) | 96342..96902 | + | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| N5O73_RS23720 (N5O73_23725) | 96906..99872 | + | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| N5O73_RS23725 (N5O73_23730) | 99908..100198 | + | 291 | Protein_103 | Ref family protein | - |
| N5O73_RS23730 (N5O73_23735) | 100277..100753 | + | 477 | Protein_104 | hypothetical protein | - |
| N5O73_RS23735 (N5O73_23740) | 100827..101084 | + | 258 | Protein_105 | IS3 family transposase IS911 | Transposase |
| N5O73_RS23740 (N5O73_23745) | 101097..102248 | - | 1152 | WP_001254932.1 | IS30 family transposase IS30D | Transposase |
| N5O73_RS23745 (N5O73_23750) | 102249..102326 | - | 78 | Protein_107 | hypothetical protein | - |
| N5O73_RS23750 (N5O73_23755) | 102314..103219 | + | 906 | Protein_108 | IS3 family transposase ISLad1 | Transposase |
| N5O73_RS23755 (N5O73_23760) | 103227..103508 | + | 282 | Protein_109 | hypothetical protein | - |
| N5O73_RS23760 (N5O73_23765) | 103562..104251 | - | 690 | WP_105318591.1 | EAL domain-containing protein | - |
| N5O73_RS23765 (N5O73_23770) | 104454..104753 | + | 300 | WP_261246515.1 | IS3 family transposase ISEc17 | Transposase |
| N5O73_RS23770 (N5O73_23775) | 104757..105617 | + | 861 | WP_261246516.1 | IS3 family transposase ISEc17 | Transposase |
| N5O73_RS23775 (N5O73_23780) | 105749..106471 | + | 723 | WP_261246518.1 | helix-turn-helix domain-containing protein | - |
| N5O73_RS23780 (N5O73_23785) | 106721..108916 | - | 2196 | Protein_114 | N-6 DNA methylase | - |
| N5O73_RS23785 (N5O73_23790) | 108992..110701 | + | 1710 | WP_094307822.1 | phage portal protein | - |
| N5O73_RS23790 (N5O73_23795) | 110694..111713 | + | 1020 | WP_095157393.1 | head processing protein | - |
| N5O73_RS23795 (N5O73_23800) | 112005..112562 | - | 558 | WP_001345478.1 | lysozyme | - |
| N5O73_RS23800 (N5O73_23805) | 112731..113219 | + | 489 | WP_000068864.1 | single-stranded DNA-binding protein | - |
| N5O73_RS23805 (N5O73_23810) | 113608..114720 | - | 1113 | WP_095157391.1 | porin OmpC | - |
| N5O73_RS23810 (N5O73_23815) | 115382..115699 | - | 318 | Protein_120 | phage tail protein | - |
| N5O73_RS23815 (N5O73_23820) | 115689..117311 | - | 1623 | Protein_121 | lytic transglycosylase domain-containing protein | - |
| N5O73_RS23825 (N5O73_23830) | 118361..118522 | + | 162 | WP_224223469.1 | AraC family transcriptional regulator | - |
| N5O73_RS23830 (N5O73_23835) | 118561..118809 | - | 249 | WP_000747846.1 | hypothetical protein | - |
| N5O73_RS23835 (N5O73_23840) | 118806..119246 | - | 441 | WP_023352064.1 | hypothetical protein | - |
| N5O73_RS23840 (N5O73_23845) | 119280..123248 | - | 3969 | Protein_126 | helicase-related protein | - |
| N5O73_RS23845 (N5O73_23850) | 123831..124082 | + | 252 | WP_001139206.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| N5O73_RS23850 (N5O73_23855) | 124079..124366 | + | 288 | WP_000222771.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| N5O73_RS23855 (N5O73_23860) | 124734..124847 | - | 114 | Protein_129 | alkaline phosphatase | - |
| N5O73_RS23860 (N5O73_23865) | 124846..125051 | + | 206 | Protein_130 | hypothetical protein | - |
| N5O73_RS23865 (N5O73_23870) | 125226..128780 | - | 3555 | WP_261246519.1 | hypothetical protein | VF |
| N5O73_RS23875 (N5O73_23880) | 130346..131245 | - | 900 | Protein_133 | IS3 family transposase ISSlo2 | Transposase |
| N5O73_RS23885 (N5O73_23890) | 132035..133186 | - | 1152 | WP_001254932.1 | IS30 family transposase IS30D | Transposase |
| N5O73_RS23890 (N5O73_23895) | 133254..133520 | - | 267 | Protein_136 | IS3 family transposase ISVch4 | Transposase |
| N5O73_RS23895 (N5O73_23900) | 133595..133855 | + | 261 | Protein_137 | IS21 family transposase IS21 | Transposase |
| N5O73_RS23900 (N5O73_23905) | 133855..134652 | + | 798 | WP_064186714.1 | IS21 family transposase IS21 | Transposase |
| N5O73_RS23905 (N5O73_23910) | 134713..135378 | + | 666 | Protein_139 | IS66 family transposase ISCro1 | Transposase |
| N5O73_RS23910 (N5O73_23915) | 135550..136284 | - | 735 | WP_064186715.1 | helix-turn-helix domain-containing protein | - |
| N5O73_RS23915 (N5O73_23920) | 136374..136682 | + | 309 | WP_059039577.1 | PerC family transcriptional regulator | - |
| N5O73_RS23920 (N5O73_23925) | 136841..137179 | + | 339 | WP_025263478.1 | c-type lysozyme inhibitor | - |
| N5O73_RS23925 (N5O73_23930) | 137736..137876 | - | 141 | WP_152930419.1 | hypothetical protein | - |
| N5O73_RS23930 (N5O73_23935) | 137959..139059 | + | 1101 | Protein_144 | IS3 family transposase IS1351 | Transposase |
| N5O73_RS23935 (N5O73_23940) | 139126..139224 | + | 99 | WP_072213849.1 | TetR family transcriptional regulator | - |
| N5O73_RS23940 (N5O73_23945) | 139555..140783 | + | 1229 | WP_153449191.1 | IS3 family transposase IS2 | Transposase |
| N5O73_RS23945 (N5O73_23950) | 141258..144731 | - | 3474 | WP_075700159.1 | cellulose synthase complex outer membrane protein BcsC | - |
| N5O73_RS23950 (N5O73_23955) | 144713..144865 | - | 153 | Protein_148 | endo-1,4-D-glucanase | - |
| N5O73_RS23955 (N5O73_23960) | 145198..145584 | - | 387 | Protein_149 | IS200-IS605 family transposase IS200C | Transposase |
| N5O73_RS23960 (N5O73_23965) | 145770..147116 | - | 1347 | WP_108991000.1 | group II intron reverse transcriptase/maturase | - |
| N5O73_RS23965 (N5O73_23970) | 147860..150010 | - | 2151 | WP_032236686.1 | cellulose biosynthesis cyclic di-GMP-binding regulatory protein BcsB | - |
| N5O73_RS23970 (N5O73_23975) | 150074..152179 | - | 2106 | WP_072663031.1 | UDP-forming cellulose synthase catalytic subunit | - |
| N5O73_RS23975 (N5O73_23980) | 152953..153650 | + | 698 | WP_095033700.1 | IS1-like element IS1B family transposase | - |
| N5O73_RS23980 (N5O73_23985) | 153697..155043 | - | 1347 | WP_159086739.1 | GGDEF domain-containing protein | - |
| N5O73_RS23985 (N5O73_23990) | 155033..157366 | - | 2334 | WP_108991002.1 | putative cyclic di-GMP phosphodiesterase PdeI | VF |
| N5O73_RS23990 (N5O73_23995) | 157876..158249 | + | 374 | Protein_156 | IS1 family transposase | - |
| N5O73_RS23995 (N5O73_24000) | 158263..158871 | + | 609 | Protein_157 | IS21 family transposase IS100kyp | Transposase |
| N5O73_RS24000 (N5O73_24005) | 158868..159649 | + | 782 | Protein_158 | IS21 family transposase IS100kyp | Transposase |
| N5O73_RS24005 (N5O73_24010) | 159741..159863 | - | 123 | Protein_159 | IS66 family insertion sequence element accessory protein TnpB | - |
| N5O73_RS24010 (N5O73_24015) | 159927..160631 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| N5O73_RS24015 (N5O73_24020) | 160976..162655 | - | 1680 | WP_247146755.1 | Ig-like domain-containing protein | - |
| N5O73_RS24020 (N5O73_24025) | 162636..163358 | - | 723 | WP_247146756.1 | DUF4165 domain-containing protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|