MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 102611 bp
Accession: NZ_CP104303 Location: 556816..659426 Organism: Lacticaseibacillus paracasei strain VHProbi O44 Replicon: chromosome
Accession: NZ_CP104303 Location: 556816..659426 Organism: Lacticaseibacillus paracasei strain VHProbi O44 Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| N4T21_RS02625 (N4T21_02625) | 552778..553677 | + | 900 | WP_003577889.1 | shikimate dehydrogenase | - |
| N4T21_RS02630 (N4T21_02630) | 554122..554937 | + | 816 | WP_003573694.1 | homoserine O-succinyltransferase | - |
| N4T21_RS02635 (N4T21_02635) | 554971..555900 | + | 930 | WP_003577893.1 | cysteine synthase A | - |
| N4T21_RS02640 (N4T21_02640) | 556090..556635 | - | 546 | WP_003577895.1 | hypothetical protein | - |
| N4T21_RS02650 (N4T21_02650) | 556956..558125 | - | 1170 | WP_003577897.1 | IS91 family transposase ISCARN110 | Transposase |
| N4T21_RS02655 (N4T21_02655) | 558238..558498 | - | 261 | WP_003573997.1 | hypothetical protein | - |
| N4T21_RS02660 (N4T21_02660) | 558588..559208 | + | 621 | WP_016368286.1 | hypothetical protein | - |
| N4T21_RS02665 (N4T21_02665) | 559192..559428 | - | 237 | WP_003572177.1 | hypothetical protein | - |
| N4T21_RS02670 (N4T21_02670) | 559621..560328 | - | 708 | WP_003572180.1 | zinc ribbon domain-containing protein | - |
| N4T21_RS02675 (N4T21_02675) | 560525..561445 | + | 921 | WP_003574021.1 | IS30 family transposase ISLpl1 | Transposase |
| N4T21_RS02680 (N4T21_02680) | 561454..561786 | + | 333 | WP_032786488.1 | hypothetical protein | - |
| N4T21_RS02685 (N4T21_02685) | 562301..562744 | + | 444 | WP_010493154.1 | ArpU family phage packaging/lysis transcriptional regulator | - |
| N4T21_RS02690 (N4T21_02690) | 563258..563632 | + | 375 | Protein_533 | hypothetical protein | - |
| N4T21_RS02695 (N4T21_02695) | 563652..564572 | - | 921 | WP_003574021.1 | IS30 family transposase ISLpl1 | Transposase |
| N4T21_RS02700 (N4T21_02700) | 564682..564966 | + | 285 | Protein_535 | hypothetical protein | - |
| N4T21_RS02705 (N4T21_02705) | 565217..566215 | + | 999 | WP_003583407.1 | IS30 family transposase ISApl1 | Transposase |
| N4T21_RS02710 (N4T21_02710) | 566411..566629 | - | 219 | WP_003573729.1 | CsbD family protein | - |
| N4T21_RS02715 (N4T21_02715) | 567052..567882 | + | 831 | WP_016369610.1 | GcrA family cell cycle regulator | - |
| N4T21_RS02720 (N4T21_02720) | 567972..568175 | + | 204 | WP_016363325.1 | hypothetical protein | - |
| N4T21_RS02725 (N4T21_02725) | 568162..568497 | + | 336 | WP_010493173.1 | ribonucleoside-diphosphate reductase | - |
| N4T21_RS02730 (N4T21_02730) | 568638..568949 | + | 312 | WP_260643003.1 | IS3 family transposase IS1163 | Transposase |
| N4T21_RS02735 (N4T21_02735) | 568979..569707 | + | 729 | WP_003582147.1 | IS3 family transposase ISSth1b | Transposase |
| N4T21_RS02740 (N4T21_02740) | 569704..570582 | + | 879 | WP_242755670.1 | IS3 family transposase ISSth1b | Transposase |
| N4T21_RS02745 (N4T21_02745) | 570661..571491 | + | 831 | WP_003583410.1 | IS3 family transposase IS1520 | Transposase |
| N4T21_RS02750 (N4T21_02750) | 572173..572451 | + | 279 | WP_003582220.1 | hypothetical protein | - |
| N4T21_RS02755 (N4T21_02755) | 572463..572729 | + | 267 | WP_003572355.1 | hypothetical protein | - |
| N4T21_RS02760 (N4T21_02760) | 572748..572924 | + | 177 | WP_003572358.1 | hypothetical protein | - |
| N4T21_RS02765 (N4T21_02765) | 572926..573153 | + | 228 | WP_003572360.1 | hypothetical protein | - |
| N4T21_RS02770 (N4T21_02770) | 573196..574437 | + | 1242 | WP_003582223.1 | hypothetical protein | - |
| N4T21_RS02775 (N4T21_02775) | 574415..575965 | + | 1551 | WP_019891186.1 | hypothetical protein | VF |
| N4T21_RS02780 (N4T21_02780) | 575975..576394 | + | 420 | WP_016368618.1 | single-stranded DNA-binding protein | - |
| N4T21_RS02785 (N4T21_02785) | 576403..576981 | + | 579 | WP_096772774.1 | hypothetical protein | - |
| N4T21_RS02790 (N4T21_02790) | 577008..579464 | + | 2457 | WP_260643004.1 | type IV secretory system conjugative DNA transfer family protein | - |
| N4T21_RS02795 (N4T21_02795) | 579461..581473 | + | 2013 | WP_260643005.1 | hypothetical protein | - |
| N4T21_RS02800 (N4T21_02800) | 581479..581814 | + | 336 | WP_003572378.1 | hypothetical protein | - |
| N4T21_RS02805 (N4T21_02805) | 581798..582394 | + | 597 | WP_003587030.1 | hypothetical protein | - |
| N4T21_RS02810 (N4T21_02810) | 582375..584303 | + | 1929 | WP_260643006.1 | ATP-binding protein | - |
| N4T21_RS02815 (N4T21_02815) | 584305..585315 | + | 1011 | WP_260643007.1 | hypothetical protein | VF |
| N4T21_RS02820 (N4T21_02820) | 585331..585975 | + | 645 | WP_260643008.1 | hypothetical protein | - |
| N4T21_RS02825 (N4T21_02825) | 585972..586379 | + | 408 | WP_016378698.1 | thioredoxin family protein | - |
| N4T21_RS02830 (N4T21_02830) | 586369..587190 | + | 822 | WP_260643009.1 | hypothetical protein | - |
| N4T21_RS02835 (N4T21_02835) | 587794..587994 | + | 201 | WP_016378700.1 | hypothetical protein | - |
| N4T21_RS02840 (N4T21_02840) | 587991..588263 | + | 273 | WP_260643010.1 | hypothetical protein | - |
| N4T21_RS02845 (N4T21_02845) | 588253..588690 | + | 438 | WP_260643011.1 | hypothetical protein | - |
| N4T21_RS02850 (N4T21_02850) | 588683..589927 | + | 1245 | WP_128532242.1 | MobP2 family relaxase | - |
| N4T21_RS02855 (N4T21_02855) | 589969..590214 | + | 246 | WP_016370737.1 | hypothetical protein | - |
| N4T21_RS02860 (N4T21_02860) | 590201..592747 | + | 2547 | WP_260643012.1 | ArdC-like ssDNA-binding domain-containing protein | - |
| N4T21_RS02865 (N4T21_02865) | 593085..593222 | + | 138 | WP_003570619.1 | putative holin-like toxin | - |
| N4T21_RS02870 (N4T21_02870) | 593344..593732 | - | 389 | Protein_569 | hypothetical protein | - |
| N4T21_RS02875 (N4T21_02875) | 593735..593878 | - | 144 | WP_003587058.1 | hypothetical protein | - |
| N4T21_RS02880 (N4T21_02880) | 593871..594320 | - | 450 | WP_260643013.1 | nitroreductase | - |
| N4T21_RS02885 (N4T21_02885) | 594334..594624 | - | 291 | WP_260643014.1 | hypothetical protein | - |
| N4T21_RS02890 (N4T21_02890) | 594634..595080 | - | 447 | WP_112199644.1 | hypothetical protein | - |
| N4T21_RS02895 (N4T21_02895) | 595584..596477 | + | 894 | WP_260643015.1 | hypothetical protein | VF |
| N4T21_RS02900 (N4T21_02900) | 596483..596842 | + | 360 | WP_014566853.1 | hypothetical protein | - |
| N4T21_RS02905 (N4T21_02905) | 596903..597687 | + | 785 | Protein_576 | IS5 family transposase | - |
| N4T21_RS02910 (N4T21_02910) | 598100..599719 | + | 1620 | WP_016386891.1 | peptide ABC transporter substrate-binding protein | - |
| N4T21_RS02915 (N4T21_02915) | 599748..600833 | + | 1086 | WP_012491759.1 | M42 family peptidase | - |
| N4T21_RS02920 (N4T21_02920) | 600833..601690 | + | 858 | WP_016370780.1 | M55 family metallopeptidase | - |
| N4T21_RS02925 (N4T21_02925) | 601694..602593 | + | 900 | WP_081528898.1 | proline iminopeptidase-family hydrolase | - |
| N4T21_RS02930 (N4T21_02930) | 602760..603680 | + | 921 | WP_016383326.1 | IS30 family transposase ISLpl1 | Transposase |
| N4T21_RS02935 (N4T21_02935) | 603686..603973 | - | 288 | WP_225365915.1 | IS3 family transposase IS1520 | Transposase |
| N4T21_RS02940 (N4T21_02940) | 604075..604803 | + | 729 | WP_081528897.1 | IS3 family transposase ISSth1b | Transposase |
| N4T21_RS02945 (N4T21_02945) | 604800..605594 | + | 795 | WP_232521946.1 | IS3 family transposase ISSth1b | Transposase |
| N4T21_RS02950 (N4T21_02950) | 605688..605996 | - | 309 | WP_032775139.1 | IS3 family transposase IS1163 | Transposase |
| N4T21_RS02955 (N4T21_02955) | 606255..607922 | + | 1668 | WP_260643016.1 | alpha-glucosidase | - |
| N4T21_RS02960 (N4T21_02960) | 607925..609664 | + | 1740 | WP_003569637.1 | glycoside hydrolase family 13 protein | - |
| N4T21_RS02965 (N4T21_02965) | 609783..612041 | + | 2259 | WP_260643017.1 | glycoside hydrolase family 65 protein | - |
| N4T21_RS02970 (N4T21_02970) | 612034..612714 | + | 681 | WP_003569641.1 | beta-phosphoglucomutase | - |
| N4T21_RS02975 (N4T21_02975) | 612707..613834 | + | 1128 | WP_003569644.1 | Oligosaccharides import ATP-binding protein MsmX | VF |
| N4T21_RS02980 (N4T21_02980) | 613847..615454 | + | 1608 | WP_016383624.1 | alpha-glucosidase | - |
| N4T21_RS02985 (N4T21_02985) | 615546..616778 | + | 1233 | WP_003569646.1 | extracellular solute-binding protein | - |
| N4T21_RS02990 (N4T21_02990) | 616832..618190 | + | 1359 | WP_003569648.1 | sugar ABC transporter permease | - |
| N4T21_RS02995 (N4T21_02995) | 618193..619050 | + | 858 | WP_003569650.1 | sugar ABC transporter permease | - |
| N4T21_RS03000 (N4T21_03000) | 619234..620190 | + | 957 | WP_003569652.1 | LacI family DNA-binding transcriptional regulator | - |
| N4T21_RS03005 (N4T21_03005) | 620249..620380 | - | 132 | Protein_596 | helix-turn-helix domain-containing protein | - |
| N4T21_RS03010 (N4T21_03010) | 620772..621056 | - | 285 | WP_016383626.1 | BRCT domain-containing protein | - |
| N4T21_RS03015 (N4T21_03015) | 621062..621712 | - | 651 | WP_003586220.1 | Tn3 family transposase TnpR_ISPa40 | Transposase |
| N4T21_RS03020 (N4T21_03020) | 621849..622130 | - | 282 | WP_003573774.1 | type II toxin-antitoxin system YafQ family toxin | Toxin Detail |
| N4T21_RS03025 (N4T21_03025) | 622123..622365 | - | 243 | WP_016363783.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin Detail |
| N4T21_RS03030 (N4T21_03030) | 622553..622834 | - | 282 | WP_260643018.1 | type II toxin-antitoxin system YafQ family toxin | Toxin Detail |
| N4T21_RS03035 (N4T21_03035) | 622827..623069 | - | 243 | WP_260643019.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin Detail |
| N4T21_RS03040 (N4T21_03040) | 623196..623564 | - | 369 | WP_003582572.1 | YxeA family protein | - |
| N4T21_RS03045 (N4T21_03045) | 623859..624209 | - | 351 | WP_003582569.1 | hypothetical protein | - |
| N4T21_RS03050 (N4T21_03050) | 624373..624462 | + | 90 | Protein_605 | IS30 family transposase | - |
| N4T21_RS03055 (N4T21_03055) | 624504..624971 | - | 468 | WP_003582565.1 | DNA starvation/stationary phase protection protein | - |
| N4T21_RS03060 (N4T21_03060) | 625481..626359 | + | 879 | WP_257710654.1 | IS3 family transposase ISBce13 | Transposase |
| N4T21_RS03065 (N4T21_03065) | 626587..627147 | + | 561 | WP_016374492.1 | hypothetical protein | - |
| N4T21_RS03070 (N4T21_03070) | 627411..627536 | + | 126 | WP_016374491.1 | IS3 family transposase IS153 | Transposase |
| N4T21_RS03075 (N4T21_03075) | 627680..628558 | + | 879 | WP_260643197.1 | IS3 family transposase ISBce13 | Transposase |
| N4T21_RS03080 (N4T21_03080) | 628870..629787 | + | 918 | WP_003582354.1 | FAD:protein FMN transferase | - |
| N4T21_RS03085 (N4T21_03085) | 629934..630542 | + | 609 | WP_003582352.1 | NAD(P)H-dependent oxidoreductase | - |
| N4T21_RS03090 (N4T21_03090) | 630553..631821 | + | 1269 | WP_003582350.1 | NADPH-dependent oxidoreductase | - |
| N4T21_RS03095 (N4T21_03095) | 632090..632518 | + | 429 | WP_003582348.1 | hypothetical protein | - |
| N4T21_RS03100 (N4T21_03100) | 632646..632822 | + | 177 | WP_003582346.1 | hypothetical protein | - |
| N4T21_RS03105 (N4T21_03105) | 632951..633421 | - | 471 | WP_016366673.1 | IS30 family transposase | - |
| N4T21_RS03110 (N4T21_03110) | 633330..633542 | - | 213 | WP_003582342.1 | IS30 family transposase ISPfr16 | Transposase |
| N4T21_RS03115 (N4T21_03115) | 633692..634375 | - | 684 | WP_016386656.1 | IS6 family transposase ISBth20 | Transposase |
| N4T21_RS03120 (N4T21_03120) | 634437..634550 | - | 114 | Protein_619 | IS30 family transposase | - |
| N4T21_RS03125 (N4T21_03125) | 634689..635219 | + | 531 | Protein_620 | ISL3 family transposase IS1165 | Transposase |
| N4T21_RS03130 (N4T21_03130) | 635346..635762 | - | 417 | WP_004563097.1 | arsenate reductase (thioredoxin) | - |
| N4T21_RS03135 (N4T21_03135) | 635785..636120 | - | 336 | WP_003582108.1 | arsenite efflux transporter metallochaperone ArsD | - |
| N4T21_RS03140 (N4T21_03140) | 636157..637452 | - | 1296 | WP_260643020.1 | arsenic transporter | - |
| N4T21_RS03145 (N4T21_03145) | 637495..639225 | - | 1731 | WP_016368213.1 | arsenical pump-driving ATPase | - |
| N4T21_RS03150 (N4T21_03150) | 639277..639600 | - | 324 | WP_003582114.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| N4T21_RS03155 (N4T21_03155) | 639723..640319 | - | 597 | WP_003582117.1 | Tn3 family transposase TnpR_TnShfr1 | Transposase |
| N4T21_RS03160 (N4T21_03160) | 640498..640761 | + | 264 | WP_003582120.1 | Tn3 family transposase TnBth1 | Transposase |
| N4T21_RS03165 (N4T21_03165) | 640816..641603 | - | 788 | Protein_628 | IS5 family transposase ISCaa8 | Transposase |
| N4T21_RS03170 (N4T21_03170) | 641568..641843 | + | 276 | WP_003582793.1 | DUF4158 domain-containing protein | - |
| N4T21_RS03175 (N4T21_03175) | 641882..642669 | + | 788 | WP_080487858.1 | IS5 family transposase | - |
| N4T21_RS03180 (N4T21_03180) | 642784..643041 | - | 258 | Protein_631 | IS5 family transposase ISLca2 | Transposase |
| N4T21_RS03185 (N4T21_03185) | 643367..644110 | + | 744 | WP_003581836.1 | Linearmycin resistance ATP-binding protein LnrL | VF |
| N4T21_RS03190 (N4T21_03190) | 644088..645335 | + | 1248 | WP_016366710.1 | ABC transporter permease | - |
| N4T21_RS03195 (N4T21_03195) | 645340..646011 | + | 672 | WP_003581839.1 | TetR/AcrR family transcriptional regulator | - |
| N4T21_RS03200 (N4T21_03200) | 646103..646786 | + | 684 | WP_016386656.1 | IS6 family transposase ISBth20 | Transposase |
| N4T21_RS03205 (N4T21_03205) | 646850..647065 | + | 216 | Protein_636 | IS30 family transposase | - |
| N4T21_RS03210 (N4T21_03210) | 647340..647603 | + | 264 | WP_003581966.1 | adenine-specific methyltransferase EcoRI family protein | - |
| N4T21_RS03215 (N4T21_03215) | 647564..648214 | + | 651 | WP_016368446.1 | putative iron export ATP-binding protein FetA | VF |
| N4T21_RS03220 (N4T21_03220) | 648211..648981 | + | 771 | WP_003581971.1 | iron export ABC transporter permease subunit FetB | - |
| N4T21_RS03225 (N4T21_03225) | 649089..650411 | - | 1323 | WP_260643021.1 | glycoside-pentoside-hexuronide (GPH):cation symporter | - |
| N4T21_RS03230 (N4T21_03230) | 650610..651494 | - | 885 | Protein_641 | IS30 family transposase ISLpl1 | Transposase |
| N4T21_RS03235 (N4T21_03235) | 651605..652012 | + | 408 | Protein_642 | IS6 family transposase ISBth20 | Transposase |
| N4T21_RS03240 (N4T21_03240) | 652070..652189 | + | 120 | Protein_643 | restriction endonuclease subunit S | - |
| N4T21_RS03245 (N4T21_03245) | 652774..653558 | + | 785 | WP_101511947.1 | IS5 family transposase ISCaa8 | Transposase |
| N4T21_RS03250 (N4T21_03250) | 653833..655365 | + | 1533 | WP_081528680.1 | ABC transporter permease/substrate-binding protein | - |
| N4T21_RS03255 (N4T21_03255) | 655365..656324 | + | 960 | WP_003567800.1 | Vitamin B12 import ATP-binding protein BtuD | VF |
| N4T21_RS03260 (N4T21_03260) | 656330..657655 | + | 1326 | WP_260643022.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| N4T21_RS03265 (N4T21_03265) | 657706..658626 | - | 921 | WP_003574021.1 | IS30 family transposase ISLpl1 | Transposase |
| N4T21_RS03270 (N4T21_03270) | 659472..660260 | + | 789 | WP_003587240.1 | hypothetical protein | - |
| N4T21_RS03275 (N4T21_03275) | 660346..661482 | - | 1137 | WP_003590076.1 | PLP-dependent transferase | - |
| N4T21_RS03280 (N4T21_03280) | 661584..662396 | - | 813 | WP_003587242.1 | transporter substrate-binding domain-containing protein | - |
| N4T21_RS03285 (N4T21_03285) | 662428..663141 | - | 714 | WP_003573812.1 | amino acid ABC transporter permease | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|