MGE detailed information
MGE type: Conjugative plasmid MGE length: 128470 bp
Accession: NZ_CP103695 Location: 1..128470 Organism: Escherichia coli strain ST12468 Replicon: plasmid pMB3825A_1
Accession: NZ_CP103695 Location: 1..128470 Organism: Escherichia coli strain ST12468 Replicon: plasmid pMB3825A_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M5T31_RS22670 (1) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| M5T31_RS22675 (1263) | 1263..2003 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| M5T31_RS22680 (2124) | 2124..2312 | - | 189 | WP_014640565.1 | hypothetical protein | - |
| M5T31_RS22690 (3463) | 3463..4365 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| M5T31_RS22695 (4434) | 4434..5543 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| M5T31_RS22700 (5976) | 5976..6929 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| M5T31_RS22705 (7033) | 7033..7422 | + | 390 | WP_001332050.1 | outer membrane protease | - |
| M5T31_RS22710 (8226) | 8226..8405 | - | 180 | Protein_8 | transposase | - |
| M5T31_RS22715 (8544) | 8544..9757 | + | 1214 | WP_162842477.1 | IS3 family transposase IS629 | Transposase |
| M5T31_RS22720 (9905) | 9905..10173 | - | 269 | Protein_10 | IS3 family transposase ISLad1 | Transposase |
| M5T31_RS22725 (10230) | 10230..10927 | + | 698 | WP_095033700.1 | IS1-like element IS1B family transposase | - |
| M5T31_RS22730 (10944) | 10944..11141 | - | 198 | Protein_12 | colicin V | - |
| M5T31_RS22735 (11119) | 11119..11355 | - | 237 | WP_014640552.1 | colicin V immunity protein | - |
| M5T31_RS22740 (11897) | 11897..12100 | - | 204 | Protein_14 | hypothetical protein | - |
| M5T31_RS22745 (12273) | 12273..12440 | + | 168 | Protein_15 | colicin-B | - |
| M5T31_RS22750 (12458) | 12458..12985 | - | 528 | WP_000203272.1 | colicin B immunity protein | - |
| M5T31_RS22755 (13229) | 13229..14044 | + | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| M5T31_RS22760 (14094) | 14094..14447 | - | 354 | WP_000864812.1 | colicin M immunity protein | - |
| M5T31_RS22765 (14625) | 14625..15416 | - | 792 | WP_000016493.1 | site-specific integrase | - |
| M5T31_RS22770 (15413) | 15413..16102 | - | 690 | WP_000796228.1 | hypothetical protein | - |
| M5T31_RS22775 (16146) | 16146..16496 | - | 351 | WP_000493379.1 | hypothetical protein | - |
| M5T31_RS22780 (17041) | 17041..18129 | + | 1089 | WP_000952217.1 | transcriptional repressor PifC | - |
| M5T31_RS22785 (18131) | 18131..20356 | + | 2226 | WP_000698737.1 | P-loop NTPase fold protein | - |
| M5T31_RS22790 (20406) | 20406..21305 | - | 900 | WP_000963206.1 | nucleotide-binding protein | - |
| M5T31_RS22795 (21295) | 21295..21585 | - | 291 | WP_000111771.1 | hypothetical protein | - |
| M5T31_RS22800 (21881) | 21881..22111 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| M5T31_RS22805 (22108) | 22108..22524 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| M5T31_RS22810 (22686) | 22686..24824 | - | 2139 | WP_000350638.1 | AAA family ATPase | - |
| M5T31_RS22815 (25178) | 25178..25435 | + | 258 | WP_000343085.1 | hypothetical protein | - |
| M5T31_RS22820 (25435) | 25435..26025 | + | 591 | WP_000194575.1 | hypothetical protein | - |
| M5T31_RS22825 (26288) | 26288..27844 | + | 1557 | WP_000818556.1 | AAA family ATPase | - |
| M5T31_RS22830 (28036) | 28036..28653 | + | 618 | WP_000521603.1 | ProQ/FINO family protein | - |
| M5T31_RS22835 (28946) | 28946..30025 | - | 1080 | WP_001089727.1 | permease | - |
| M5T31_RS22840 (30130) | 30130..30453 | + | 324 | WP_001175594.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| M5T31_RS22845 (30614) | 30614..30934 | + | 321 | Protein_35 | NAD(P)H-dependent oxidoreductase | - |
| M5T31_RS22850 (30987) | 30987..31691 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5T31_RS22855 (31798) | 31798..32658 | + | 861 | WP_000557452.1 | SPbeta prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| M5T31_RS22860 (32671) | 32671..33213 | + | 543 | WP_002063889.1 | AAA family ATPase | - |
| M5T31_RS22865 (33305) | 33305..34353 | + | 1049 | Protein_39 | IS3 family transposase ISKpn11 | Transposase |
| M5T31_RS22870 (34407) | 34407..35111 | - | 705 | WP_259409785.1 | IS6 family transposase IS26 | Transposase |
| M5T31_RS22875 (35188) | 35188..37551 | - | 2364 | Protein_41 | Tn3 family transposase TnpA_Tn3 | Transposase |
| M5T31_RS22880 (37601) | 37601..38305 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5T31_RS22885 (38371) | 38371..39885 | + | 1515 | Protein_43 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| M5T31_RS22890 (39943) | 39943..40185 | + | 243 | WP_000844627.1 | transposase | - |
| M5T31_RS22895 (40217) | 40217..40867 | - | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| M5T31_RS22900 (40973) | 40973..42172 | + | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| M5T31_RS22905 (42204) | 42204..43088 | - | 885 | WP_000058717.1 | EamA family transporter | - |
| M5T31_RS22910 (43226) | 43226..43618 | - | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| M5T31_RS22915 (43622) | 43622..45202 | + | 1581 | Protein_49 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| M5T31_RS22920 (45253) | 45253..45957 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5T31_RS22925 (46023) | 46023..46307 | + | 285 | Protein_51 | IS6 family transposase IS26 | Transposase |
| M5T31_RS22930 (46497) | 46497..47312 | - | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| M5T31_RS22935 (47463) | 47463..48167 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5T31_RS22940 (48213) | 48213..48356 | + | 144 | Protein_54 | helix-turn-helix domain-containing protein | - |
| M5T31_RS22945 (48359) | 48359..51325 | + | 2967 | WP_001138064.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| M5T31_RS22950 (51294) | 51294..51938 | - | 645 | WP_223667713.1 | hypothetical protein | - |
| M5T31_RS22955 (51938) | 51938..52192 | - | 255 | WP_000343103.1 | hypothetical protein | - |
| M5T31_RS22960 (52544) | 52544..53545 | + | 1002 | WP_000774874.1 | DUF4238 domain-containing protein | - |
| M5T31_RS22965 (53721) | 53721..54065 | - | 345 | WP_000793307.1 | hypothetical protein | - |
| M5T31_RS22970 (54651) | 54651..55355 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5T31_RS22975 (55421) | 55421..55966 | + | 546 | Protein_61 | Tn3 family transposase TnpA_Tn3 | Transposase |
| M5T31_RS22980 (56002) | 56002..56417 | - | 416 | Protein_62 | IS1 family transposase | - |
| M5T31_RS22985 (56666) | 56666..57067 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| M5T31_RS22990 (57000) | 57000..57257 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| M5T31_RS22995 (57350) | 57350..58003 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| M5T31_RS23000 (58943) | 58943..59800 | - | 858 | WP_000130940.1 | incFII family plasmid replication initiator RepA | - |
| M5T31_RS23005 (59793) | 59793..59840 | - | 48 | WP_077822033.1 | hypothetical protein | - |
| M5T31_RS23010 (59831) | 59831..60067 | + | 237 | WP_223368648.1 | replication protein RepA | - |
| M5T31_RS23015 (60093) | 60093..60353 | - | 261 | WP_000083818.1 | replication regulatory protein RepA | - |
| M5T31_RS23020 (60592) | 60592..61165 | - | 574 | Protein_70 | DUF2726 domain-containing protein | - |
| M5T31_RS23025 (61203) | 61203..61412 | - | 210 | WP_001333231.1 | hemolysin expression modulator Hha | - |
| M5T31_RS23030 (61458) | 61458..61919 | - | 462 | WP_001233871.1 | thermonuclease family protein | - |
| M5T31_RS23035 (62162) | 62162..62374 | - | 213 | WP_012311405.1 | hypothetical protein | - |
| M5T31_RS23040 (62512) | 62512..63072 | - | 561 | WP_000139359.1 | fertility inhibition protein FinO | - |
| M5T31_RS23045 (63127) | 63127..63873 | - | 747 | WP_000205777.1 | conjugal transfer pilus acetylase TraX | - |
| M5T31_RS23050 (63893) | 63893..69163 | - | 5271 | WP_000986979.1 | Multifunctional conjugation protein TraI | Relaxase |
| M5T31_RS23055 (69163) | 69163..71325 | - | 2163 | WP_101740172.1 | type IV conjugative transfer system coupling protein TraD | - |
| M5T31_RS23060 (71578) | 71578..72309 | - | 732 | WP_000850422.1 | conjugal transfer complement resistance protein TraT | - |
| M5T31_RS23065 (72341) | 72341..72844 | - | 504 | WP_000605510.1 | hypothetical protein | - |
| M5T31_RS23070 (72859) | 72859..75681 | - | 2823 | WP_001007026.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| M5T31_RS23075 (75678) | 75678..77051 | - | 1374 | WP_001137358.1 | conjugal transfer pilus assembly protein TraH | - |
| M5T31_RS23080 (77051) | 77051..77413 | - | 363 | WP_001443292.1 | P-type conjugative transfer protein TrbJ | - |
| M5T31_RS23085 (77343) | 77343..77888 | - | 546 | WP_000052618.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| M5T31_RS23090 (77875) | 77875..78159 | - | 285 | WP_000624110.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| M5T31_RS23095 (78278) | 78278..78625 | - | 348 | WP_001287893.1 | conjugal transfer protein TrbA | - |
| M5T31_RS23100 (78641) | 78641..79384 | - | 744 | WP_001030378.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| M5T31_RS23105 (79377) | 79377..79634 | - | 258 | WP_000864325.1 | conjugal transfer protein TrbE | - |
| M5T31_RS23110 (79661) | 79661..81469 | - | 1809 | WP_000821821.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| M5T31_RS23115 (81466) | 81466..82104 | - | 639 | WP_001104248.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| M5T31_RS23120 (82132) | 82132..82584 | - | 453 | WP_000069427.1 | hypothetical protein | - |
| M5T31_RS23125 (82614) | 82614..83075 | - | 462 | WP_000277845.1 | hypothetical protein | - |
| M5T31_RS23130 (83101) | 83101..84093 | - | 993 | WP_000830839.1 | conjugal transfer pilus assembly protein TraU | - |
| M5T31_RS23135 (84090) | 84090..84722 | - | 633 | WP_001203745.1 | type-F conjugative transfer system protein TraW | - |
| M5T31_RS23140 (84719) | 84719..85105 | - | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| M5T31_RS23145 (85102) | 85102..87729 | - | 2628 | WP_001064268.1 | type IV secretion system protein TraC | - |
| M5T31_RS23155 (89264) | 89264..89446 | - | 183 | WP_259430773.1 | conjugal transfer protein TraR | - |
| M5T31_RS23160 (89581) | 89581..90096 | - | 516 | WP_000809906.1 | type IV conjugative transfer system lipoprotein TraV | - |
| M5T31_RS23165 (90093) | 90093..90344 | - | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
| M5T31_RS23170 (90341) | 90341..90658 | - | 318 | WP_001057292.1 | conjugal transfer protein TrbD | - |
| M5T31_RS23175 (90655) | 90655..91227 | - | 573 | WP_000002780.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| M5T31_RS23180 (91217) | 91217..92644 | - | 1428 | WP_000146685.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| M5T31_RS23185 (92644) | 92644..93372 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| M5T31_RS23190 (93359) | 93359..93925 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| M5T31_RS23195 (93947) | 93947..94258 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| M5T31_RS23200 (94273) | 94273..94632 | - | 360 | WP_000340272.1 | type IV conjugative transfer system pilin TraA | - |
| M5T31_RS23205 (94666) | 94666..94893 | - | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| M5T31_RS23210 (94987) | 94987..95673 | - | 687 | WP_000332484.1 | PAS domain-containing protein | - |
| M5T31_RS23215 (95864) | 95864..96247 | - | 384 | WP_000124981.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| M5T31_RS23220 (96524) | 96524..97171 | + | 648 | WP_000614936.1 | hypothetical protein | VF |
| M5T31_RS23225 (97468) | 97468..98289 | - | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| M5T31_RS23230 (98412) | 98412..98699 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| M5T31_RS23235 (98724) | 98724..98930 | - | 207 | WP_000547939.1 | hypothetical protein | - |
| M5T31_RS23240 (99000) | 99000..99173 | + | 174 | Protein_114 | hypothetical protein | - |
| M5T31_RS23245 (99171) | 99171..99401 | - | 231 | WP_001426396.1 | hypothetical protein | - |
| M5T31_RS23250 (99621) | 99621..99746 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| M5T31_RS23255 (99688) | 99688..99837 | - | 150 | Protein_117 | plasmid maintenance protein Mok | - |
| - (99823) | 99823..100047 | - | 225 | NuclAT_0 | - | - |
| - (99823) | 99823..100047 | - | 225 | NuclAT_0 | - | - |
| - (99823) | 99823..100047 | - | 225 | NuclAT_0 | - | - |
| - (99823) | 99823..100047 | - | 225 | NuclAT_0 | - | - |
| M5T31_RS23260 (99859) | 99859..100047 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| M5T31_RS23265 (100016) | 100016..100778 | - | 763 | Protein_119 | plasmid SOS inhibition protein A | - |
| M5T31_RS23270 (100775) | 100775..101209 | - | 435 | WP_000845895.1 | conjugation system SOS inhibitor PsiB | - |
| M5T31_RS23275 (101264) | 101264..103222 | - | 1959 | WP_001145469.1 | ParB/RepB/Spo0J family partition protein | - |
| M5T31_RS23280 (103281) | 103281..103514 | - | 234 | WP_000006004.1 | DUF905 domain-containing protein | - |
| M5T31_RS23285 (103570) | 103570..104097 | - | 528 | WP_000290793.1 | single-stranded DNA-binding protein | - |
| M5T31_RS23290 (104570) | 104570..104854 | - | 285 | WP_124767219.1 | hypothetical protein | - |
| M5T31_RS23295 (104740) | 104740..105006 | - | 267 | WP_001697809.1 | hypothetical protein | - |
| M5T31_RS23300 (105006) | 105006..105569 | - | 564 | WP_001311069.1 | class I SAM-dependent methyltransferase | - |
| M5T31_RS23305 (105615) | 105615..106976 | - | 1362 | WP_000170681.1 | DUF3560 domain-containing protein | - |
| M5T31_RS23310 (107028) | 107028..107258 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| M5T31_RS23315 (107775) | 107775..108028 | + | 254 | Protein_129 | hypothetical protein | - |
| M5T31_RS23320 (108252) | 108252..108434 | - | 183 | WP_001027505.1 | hypothetical protein | - |
| M5T31_RS23325 (108434) | 108434..108895 | - | 462 | WP_042007484.1 | DUF1380 family protein | - |
| M5T31_RS23330 (108895) | 108895..109320 | - | 426 | WP_001198922.1 | antirestriction protein | - |
| M5T31_RS23335 (109722) | 109722..110693 | + | 972 | WP_000082154.1 | IS110 family transposase ISEc32 | Transposase |
| M5T31_RS23345 (111494) | 111494..111829 | - | 336 | WP_000343070.1 | hypothetical protein | - |
| M5T31_RS23350 (111898) | 111898..112245 | - | 348 | WP_001350917.1 | hypothetical protein | - |
| M5T31_RS23355 (112242) | 112242..112411 | - | 170 | Protein_137 | hypothetical protein | - |
| M5T31_RS23360 (113048) | 113048..114019 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| M5T31_RS23365 (114019) | 114019..115185 | - | 1167 | WP_001238646.1 | hypothetical protein | VF |
| M5T31_RS23375 (116338) | 116338..117840 | - | 1503 | WP_000715078.1 | hypothetical protein | - |
| M5T31_RS23380 (118449) | 118449..118874 | - | 426 | WP_012300440.1 | hypothetical protein | - |
| M5T31_RS23385 (119016) | 119016..119495 | + | 480 | WP_000190053.1 | hypothetical protein | - |
| M5T31_RS23390 (119935) | 119935..120186 | + | 252 | WP_000163248.1 | hypothetical protein | - |
| M5T31_RS23395 (120159) | 120159..120290 | - | 132 | Protein_145 | phosphopyruvate hydratase | - |
| M5T31_RS23400 (120288) | 120288..120545 | + | 258 | Protein_146 | transposase | - |
| M5T31_RS23405 (120779) | 120779..121636 | - | 858 | WP_000968140.1 | Manganese transport system membrane protein MntB | ARG |
| M5T31_RS23410 (121633) | 121633..122490 | - | 858 | WP_000992806.1 | Manganese transport system membrane protein MntB | ARG |
| M5T31_RS23415 (122487) | 122487..123314 | - | 828 | WP_000983710.1 | Manganese transport system ATP-binding protein MntB | VF |
| M5T31_RS23420 (123314) | 123314..124228 | - | 915 | WP_000949004.1 | putative periplasmic iron-binding protein | VF |
| M5T31_RS23425 (124584) | 124584..125281 | + | 698 | WP_223155668.1 | IS1 family transposase IS1S | Transposase |
| M5T31_RS23430 (125461) | 125461..125974 | - | 514 | Protein_152 | DUF4113 domain-containing protein | - |
| M5T31_RS23435 (126035) | 126035..126139 | - | 105 | Protein_153 | AAA family ATPase | - |
| M5T31_RS23440 (126141) | 126141..126464 | - | 324 | Protein_154 | IS21 family transposase IS21 | Transposase |
| M5T31_RS23445 (126713) | 126713..127926 | + | 1214 | WP_085947772.1 | IS3 family transposase ISCfr6 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|