MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 122603 bp
Accession: NZ_CP103466 Location: 1..122603 Organism: Escherichia coli O25b:H4-ST131 strain 5392 Replicon: plasmid pMB9877_1
Accession: NZ_CP103466 Location: 1..122603 Organism: Escherichia coli O25b:H4-ST131 strain 5392 Replicon: plasmid pMB9877_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M5T42_RS23170 (1) | 1..756 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| M5T42_RS23175 (1344) | 1344..2510 | + | 1167 | WP_000772446.1 | hypothetical protein | VF |
| M5T42_RS23180 (2510) | 2510..3481 | + | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| M5T42_RS23185 (4348) | 4348..5250 | + | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| M5T42_RS23190 (5247) | 5247..5558 | + | 312 | WP_032143366.1 | hypothetical protein | - |
| M5T42_RS23195 (5635) | 5635..6318 | + | 684 | WP_000086185.1 | DNA methylase | - |
| M5T42_RS23200 (6319) | 6319..6540 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| M5T42_RS23205 (6470) | 6470..6988 | + | 519 | WP_123325260.1 | DUF1380 family protein | - |
| M5T42_RS23210 (7039) | 7039..7815 | + | 777 | WP_001753849.1 | hypothetical protein | - |
| M5T42_RS23215 (8232) | 8232..8657 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| M5T42_RS23220 (8704) | 8704..9126 | + | 423 | WP_000271753.1 | DUF1380 family protein | - |
| M5T42_RS23225 (9123) | 9123..9314 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| M5T42_RS23230 (10349) | 10349..10579 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| M5T42_RS23235 (10631) | 10631..11992 | + | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| M5T42_RS23240 (12040) | 12040..12603 | + | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| M5T42_RS23245 (12629) | 12629..12871 | + | 243 | WP_001617878.1 | hypothetical protein | - |
| M5T42_RS23250 (12927) | 12927..13624 | + | 698 | WP_223216367.1 | IS1 family transposase IS1G | Transposase |
| M5T42_RS23255 (13672) | 13672..13992 | + | 321 | WP_001348757.1 | conjugal transfer protein TrbA | - |
| M5T42_RS23260 (14119) | 14119..14403 | + | 285 | WP_001617873.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| M5T42_RS23265 (14390) | 14390..14935 | + | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| M5T42_RS23270 (14865) | 14865..15212 | + | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| M5T42_RS23275 (15193) | 15193..15585 | + | 393 | WP_000659962.1 | F-type conjugal transfer protein TrbF | - |
| M5T42_RS23280 (15572) | 15572..16945 | + | 1374 | WP_000944328.1 | conjugal transfer pilus assembly protein TraH | - |
| M5T42_RS23285 (16942) | 16942..19761 | + | 2820 | WP_001007062.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| M5T42_RS23290 (19780) | 19780..20277 | + | 498 | WP_000605862.1 | entry exclusion protein | - |
| M5T42_RS23295 (20309) | 20309..21040 | + | 732 | WP_000850429.1 | conjugal transfer complement resistance protein TraT | - |
| M5T42_RS23300 (21243) | 21243..21980 | + | 738 | WP_012881122.1 | hypothetical protein | - |
| M5T42_RS23305 (22031) | 22031..24256 | + | 2226 | WP_156655430.1 | type IV conjugative transfer system coupling protein TraD | - |
| M5T42_RS23310 (24256) | 24256..29526 | + | 5271 | WP_000948349.1 | Multifunctional conjugation protein TraI | Relaxase |
| M5T42_RS23315 (29546) | 29546..30292 | + | 747 | WP_059338983.1 | conjugal transfer pilus acetylase TraX | - |
| M5T42_RS23320 (30351) | 30351..31211 | + | 861 | WP_000704523.1 | Quorum-quenching protein AidA | VF |
| M5T42_RS23325 (31314) | 31314..31874 | + | 561 | WP_000139321.1 | fertility inhibition protein FinO | - |
| M5T42_RS23330 (32003) | 32003..32215 | + | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| M5T42_RS23335 (32460) | 32460..32921 | + | 462 | WP_001233838.1 | thermonuclease family protein | - |
| M5T42_RS23340 (32967) | 32967..33176 | + | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| M5T42_RS23345 (33214) | 33214..33804 | + | 591 | WP_000766807.1 | DUF2726 domain-containing protein | - |
| M5T42_RS23350 (33959) | 33959..34432 | + | 474 | WP_187810334.1 | hypothetical protein | - |
| - (34575) | 34575..34634 | - | 60 | NuclAT_0 | - | Antitoxin Detail |
| - (34575) | 34575..34634 | - | 60 | NuclAT_0 | - | Antitoxin Detail |
| - (34575) | 34575..34634 | - | 60 | NuclAT_0 | - | Antitoxin Detail |
| - (34575) | 34575..34634 | - | 60 | NuclAT_0 | - | Antitoxin Detail |
| M5T42_RS23355 (34679) | 34679..34828 | + | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| M5T42_RS23360 (35113) | 35113..35361 | + | 249 | WP_000083839.1 | replication regulatory protein RepA | - |
| M5T42_RS23365 (35606) | 35606..35680 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| M5T42_RS23370 (35673) | 35673..36530 | + | 858 | WP_016240488.1 | incFII family plasmid replication initiator RepA | - |
| M5T42_RS23375 (37457) | 37457..38110 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| M5T42_RS23380 (38203) | 38203..38460 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| M5T42_RS23385 (38393) | 38393..38794 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| M5T42_RS23390 (39043) | 39043..39740 | + | 698 | WP_151884388.1 | IS1 family transposase IS1R | Transposase |
| M5T42_RS23395 (39755) | 39755..39973 | + | 219 | Protein_45 | IS4 family transposase | - |
| M5T42_RS23400 (40023) | 40023..40727 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5T42_RS23405 (41041) | 41041..41916 | + | 876 | WP_032277257.1 | Beta-lactamase CTX-M-97 | ARG |
| M5T42_RS23410 (41951) | 41951..42313 | + | 363 | Protein_48 | IS5 family transposase IS903B | Transposase |
| M5T42_RS23415 (42373) | 42373..43077 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| M5T42_RS23420 (43130) | 43130..43462 | + | 333 | Protein_50 | EamA family transporter | - |
| M5T42_RS23425 (43494) | 43494..44693 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| M5T42_RS23430 (44799) | 44799..45425 | + | 627 | WP_031606906.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| M5T42_RS23435 (45457) | 45457..45693 | - | 237 | WP_042005022.1 | hypothetical protein | - |
| M5T42_RS23440 (45747) | 45747..46583 | - | 837 | WP_000480972.1 | hypothetical protein | ARG |
| M5T42_RS23445 (46583) | 46583..47386 | - | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| M5T42_RS23450 (47447) | 47447..48262 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| M5T42_RS23455 (48570) | 48570..48746 | - | 177 | Protein_57 | replication protein C, IncQ-type | - |
| M5T42_RS23460 (48807) | 48807..49511 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5T42_RS23465 (49633) | 49633..50538 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| M5T42_RS23470 (50535) | 50535..51773 | + | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| M5T42_RS23475 (51773) | 51773..52357 | + | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| M5T42_RS23480 (52850) | 52850..53614 | - | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| M5T42_RS23485 (53732) | 53732..53797 | - | 66 | Protein_63 | EAL domain-containing protein | - |
| M5T42_RS23490 (53841) | 53841..54146 | - | 306 | WP_000130000.1 | Transcriptional regulator | Relaxase |
| M5T42_RS23495 (54157) | 54157..55362 | - | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| M5T42_RS23500 (55518) | 55518..55721 | - | 204 | WP_000376616.1 | hypothetical protein | - |
| M5T42_RS23505 (55849) | 55849..56688 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| M5T42_RS23510 (56682) | 56682..57029 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| M5T42_RS23515 (57235) | 57235..58023 | - | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| M5T42_RS23520 (58154) | 58154..58627 | - | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| M5T42_RS23525 (58785) | 58785..59534 | + | 750 | Protein_71 | IS91 family transposase ISAzo26 | Transposase |
| M5T42_RS23530 (59593) | 59593..60297 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| M5T42_RS23535 (60347) | 60347..60565 | - | 219 | Protein_73 | IS4 family transposase | - |
| M5T42_RS23545 (61477) | 61477..61590 | + | 114 | Protein_75 | IS6 family transposase | - |
| M5T42_RS23550 (61728) | 61728..61898 | + | 171 | Protein_76 | DsbA family protein | - |
| M5T42_RS23555 (61888) | 61888..62394 | + | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| M5T42_RS23560 (62631) | 62631..63392 | + | 762 | WP_001225378.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| M5T42_RS23565 (63739) | 63739..65625 | + | 1887 | WP_000118029.1 | FTR1 family protein | - |
| M5T42_RS23570 (65666) | 65666..66193 | + | 528 | WP_000178050.1 | iron transporter | - |
| M5T42_RS23575 (66297) | 66297..67676 | + | 1380 | WP_000119836.1 | Fe-S-containing protein | - |
| M5T42_RS23580 (67679) | 67679..68962 | + | 1284 | WP_000964653.1 | ABC transporter permease | - |
| M5T42_RS23585 (68952) | 68952..70082 | + | 1131 | WP_000729218.1 | ABC transporter permease | - |
| M5T42_RS23590 (70087) | 70087..70782 | + | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| M5T42_RS23595 (70769) | 70769..71254 | + | 486 | WP_001267176.1 | TlpA disulfide reductase family protein | - |
| M5T42_RS23600 (71279) | 71279..71764 | + | 486 | WP_000874189.1 | hypothetical protein | - |
| M5T42_RS23605 (71886) | 71886..72519 | + | 634 | Protein_87 | histidine-type phosphatase | - |
| M5T42_RS23610 (72669) | 72669..72842 | - | 174 | Protein_88 | IS5 family transposase ISKpn26 | Transposase |
| M5T42_RS23615 (72843) | 72843..73157 | - | 315 | Protein_89 | IS5 family transposase ISKpn26 | Transposase |
| M5T42_RS23620 (73830) | 73830..74569 | - | 740 | Protein_90 | IS3 family transposase IS629 | Transposase |
| M5T42_RS23625 (74671) | 74671..74931 | + | 261 | WP_000371882.1 | hypothetical protein | - |
| M5T42_RS23630 (74928) | 74928..75437 | + | 510 | WP_000194542.1 | hypothetical protein | - |
| M5T42_RS23635 (75457) | 75457..75804 | - | 348 | WP_000142452.1 | DUF6404 family protein | - |
| M5T42_RS23640 (75933) | 75933..76268 | + | 336 | WP_001080732.1 | colicin E1 family microcin immunity protein | - |
| M5T42_RS23645 (77720) | 77720..78345 | + | 626 | Protein_95 | replication initiation protein | - |
| M5T42_RS23650 (78719) | 78719..79594 | + | 876 | WP_001224623.1 | ChaN family lipoprotein | - |
| M5T42_RS23655 (79602) | 79602..80378 | + | 777 | WP_000981091.1 | energy transducer TonB | - |
| M5T42_RS23660 (80547) | 80547..82808 | + | 2262 | WP_001100763.1 | TonB-dependent receptor | - |
| M5T42_RS23665 (82877) | 82877..84052 | + | 1176 | WP_001020413.1 | putative protein YncE | VF |
| M5T42_RS23670 (84575) | 84575..84880 | - | 306 | Protein_100 | IS91 family transposase ISSbo1 | Transposase |
| M5T42_RS23675 (84906) | 84906..85645 | + | 740 | Protein_101 | IS3 family transposase IS629 | Transposase |
| M5T42_RS23680 (86318) | 86318..87826 | + | 1509 | WP_001189113.1 | group II intron reverse transcriptase/maturase | - |
| M5T42_RS23685 (87910) | 87910..88248 | + | 339 | Protein_103 | IS3 family transposase IS629 | Transposase |
| M5T42_RS23690 (88328) | 88328..88732 | + | 405 | WP_000839179.1 | IS66 family transposase ISEc22 | Transposase |
| M5T42_RS23695 (88729) | 88729..89076 | + | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
| M5T42_RS23700 (89125) | 89125..90070 | + | 946 | Protein_106 | IS66 family transposase ISEc8 | Transposase |
| M5T42_RS23705 (90156) | 90156..91178 | + | 1023 | WP_001310017.1 | IS21 family transposase IS100kyp | Transposase |
| M5T42_RS23710 (91175) | 91175..91957 | + | 783 | WP_001300609.1 | IS21 family transposase IS100kyp | Transposase |
| M5T42_RS23715 (92025) | 92025..92633 | + | 609 | Protein_109 | IS66 family transposase ISEc22 | Transposase |
| M5T42_RS23720 (92696) | 92696..93487 | - | 792 | WP_000977394.1 | DUF4198 domain-containing protein | - |
| M5T42_RS23725 (93494) | 93494..95464 | - | 1971 | WP_001298664.1 | Hemin receptor | VF |
| M5T42_RS23730 (95746) | 95746..96170 | + | 425 | Protein_112 | IS3 family transposase IS2 | Transposase |
| M5T42_RS23735 (96707) | 96707..96979 | + | 273 | WP_001322642.1 | adhesin biosynthesis transcription regulatory family protein | - |
| M5T42_RS23740 (97425) | 97425..97600 | + | 176 | Protein_114 | IS3 family transposase | - |
| M5T42_RS23745 (97826) | 97826..98995 | - | 1170 | WP_001072358.1 | hypothetical protein | - |
| M5T42_RS23750 (99362) | 99362..99550 | + | 189 | WP_001309252.1 | hypothetical protein | - |
| M5T42_RS23755 (99671) | 99671..100411 | + | 741 | WP_001066941.1 | tyrosine-type recombinase/integrase | - |
| M5T42_RS23760 (100696) | 100696..101673 | - | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| M5T42_RS23765 (102429) | 102429..103400 | + | 972 | Protein_119 | hypothetical protein | - |
| M5T42_RS23770 (103559) | 103559..103717 | - | 159 | WP_228955855.1 | abortive infection family protein | - |
| M5T42_RS23775 (103865) | 103865..104562 | + | 698 | WP_223293341.1 | IS1 family transposase IS1R | Transposase |
| M5T42_RS23780 (104578) | 104578..104907 | + | 330 | Protein_122 | TOBE domain-containing protein | - |
| M5T42_RS23785 (105016) | 105016..105948 | - | 933 | WP_000081352.1 | homocysteine S-methyltransferase | - |
| M5T42_RS23790 (105935) | 105935..107338 | - | 1404 | WP_001373486.1 | S-methylmethionine permease | - |
| M5T42_RS23795 (107582) | 107582..108562 | + | 981 | WP_000019407.1 | IS5 family transposase IS5D | Transposase |
| M5T42_RS23800 (108772) | 108772..109107 | + | 336 | WP_169329198.1 | type I deoxyribonuclease HsdR | - |
| M5T42_RS23805 (109057) | 109057..109470 | - | 414 | Protein_127 | IS3 family transposase ISLad1 | Transposase |
| M5T42_RS23810 (109475) | 109475..109753 | - | 279 | Protein_128 | pdcB | - |
| M5T42_RS23815 (109781) | 109781..109960 | - | 180 | WP_001513661.1 | hypothetical protein | - |
| M5T42_RS23820 (109965) | 109965..110345 | - | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| M5T42_RS23825 (110345) | 110345..110566 | - | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| M5T42_RS23830 (110749) | 110749..112305 | + | 1557 | WP_001617892.1 | type I restriction-modification system subunit M | - |
| M5T42_RS23835 (112302) | 112302..113573 | + | 1272 | WP_023142242.1 | restriction endonuclease subunit S | - |
| M5T42_RS23840 (113695) | 113695..116811 | + | 3117 | WP_001553854.1 | HsdR family type I site-specific deoxyribonuclease | - |
| M5T42_RS23845 (117025) | 117025..117722 | + | 698 | WP_103215986.1 | IS1 family transposase IS1G | Transposase |
| M5T42_RS23850 (117859) | 117859..118752 | - | 894 | WP_001553853.1 | S-4TM family putative pore-forming effector | - |
| M5T42_RS23855 (118795) | 118795..119790 | - | 996 | WP_000246636.1 | hypothetical protein | - |
| M5T42_RS23860 (120498) | 120498..120716 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | - |
| M5T42_RS23865 (120718) | 120718..121023 | + | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | - |
| M5T42_RS23870 (121024) | 121024..121830 | + | 807 | WP_000016982.1 | site-specific integrase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|