MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 83447 bp
Accession: NZ_CP103319 Location: 1..83447 Organism: Klebsiella pneumoniae strain hvKP12 Replicon: plasmid phvKP12-KPC
Accession: NZ_CP103319 Location: 1..83447 Organism: Klebsiella pneumoniae strain hvKP12 Replicon: plasmid phvKP12-KPC
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NXZ72_RS29445 (1) | 1..858 | + | 858 | WP_032495102.1 | incFII family plasmid replication initiator RepA | - |
| NXZ72_RS29450 (1797) | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| NXZ72_RS29455 (2543) | 2543..2800 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| NXZ72_RS29460 (2733) | 2733..3134 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| NXZ72_RS29465 (3383) | 3383..3798 | + | 416 | Protein_4 | IS1 family transposase IS1R | Transposase |
| NXZ72_RS29470 (3834) | 3834..4379 | - | 546 | Protein_5 | Tn3 family transposase TnpA_Tn3 | Transposase |
| NXZ72_RS29475 (4445) | 4445..5149 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NXZ72_RS29480 (5219) | 5219..5410 | + | 192 | Protein_7 | IS1380 family transposase | - |
| NXZ72_RS29485 (5660) | 5660..6535 | + | 876 | WP_013188475.1 | Beta-lactamase Toho-1 | ARG |
| NXZ72_RS29490 (6570) | 6570..7538 | + | 969 | WP_013362812.1 | IS5 family transposase IS903B | Transposase |
| NXZ72_RS29495 (7595) | 7595..8692 | + | 1098 | Protein_10 | TonB-dependent receptor | - |
| NXZ72_RS29500 (8760) | 8760..9101 | - | 342 | Protein_11 | PAS domain-containing protein | - |
| NXZ72_RS29505 (9167) | 9167..9871 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NXZ72_RS29510 (9925) | 9925..10248 | - | 324 | Protein_13 | class II aldolase/adducin family protein | - |
| NXZ72_RS29515 (10241) | 10241..11493 | - | 1253 | Protein_14 | four-carbon acid sugar kinase family protein | - |
| NXZ72_RS29520 (11505) | 11505..12407 | - | 903 | WP_002903955.1 | NAD(P)-dependent oxidoreductase | - |
| NXZ72_RS29525 (12669) | 12669..13430 | + | 762 | WP_002210513.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| NXZ72_RS29530 (13451) | 13451..14311 | - | 861 | WP_002904004.1 | Beta-lactamase SHV-2 | ARG |
| NXZ72_RS29535 (14448) | 14448..14516 | + | 69 | Protein_18 | IS6 family transposase | - |
| NXZ72_RS29540 (14552) | 14552..17518 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| NXZ72_RS29545 (17522) | 17522..18082 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| NXZ72_RS29550 (18474) | 18474..19091 | + | 618 | Protein_21 | replication protein | - |
| NXZ72_RS29555 (19625) | 19625..19903 | + | 279 | WP_013213990.1 | hypothetical protein | - |
| NXZ72_RS29560 (20014) | 20014..20439 | + | 426 | WP_013213989.1 | antirestriction protein | - |
| NXZ72_RS29565 (20567) | 20567..20722 | + | 156 | WP_013213988.1 | hypothetical protein | - |
| NXZ72_RS29570 (20768) | 20768..21064 | + | 297 | WP_013213987.1 | transcriptional regulator | - |
| NXZ72_RS29575 (21168) | 21168..22049 | + | 882 | Protein_26 | IS1182 family transposase ISKpn6 | Transposase |
| NXZ72_RS29580 (22299) | 22299..23180 | - | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| NXZ72_RS29585 (23456) | 23456..24436 | - | 981 | WP_013213985.1 | IS481 family transposase ISKpn27 | Transposase |
| NXZ72_RS29590 (24559) | 24559..25020 | - | 462 | Protein_29 | Tn3 family transposase TnpR_Tn3 | Transposase |
| NXZ72_RS29595 (25072) | 25072..25776 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NXZ72_RS29600 (25841) | 25841..27013 | - | 1173 | Protein_31 | transposase | - |
| NXZ72_RS29605 (27088) | 27088..27756 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| NXZ72_RS29610 (27792) | 27792..28028 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| NXZ72_RS29615 (28025) | 28025..28387 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| NXZ72_RS29620 (28405) | 28405..30099 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| NXZ72_RS29625 (30151) | 30151..30573 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| NXZ72_RS29630 (30609) | 30609..30884 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| NXZ72_RS29635 (30898) | 30898..31248 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| NXZ72_RS29640 (31320) | 31320..31754 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| NXZ72_RS29645 (31833) | 31833..32837 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| NXZ72_RS29650 (33117) | 33117..33389 | - | 273 | Protein_41 | transposase | - |
| NXZ72_RS29660 (34371) | 34371..35393 | - | 1023 | WP_000361404.1 | helicase UvrD | - |
| NXZ72_RS29665 (35378) | 35378..36940 | - | 1563 | WP_004206609.1 | AAA family ATPase | - |
| NXZ72_RS29670 (37014) | 37014..37430 | - | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| NXZ72_RS29675 (37427) | 37427..37657 | - | 231 | WP_001261282.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| NXZ72_RS29680 (37614) | 37614..38075 | + | 462 | WP_014343465.1 | hypothetical protein | - |
| NXZ72_RS29685 (38236) | 38236..39180 | + | 945 | WP_011977810.1 | hypothetical protein | - |
| NXZ72_RS29690 (39217) | 39217..39609 | + | 393 | WP_011977811.1 | hypothetical protein | - |
| NXZ72_RS29695 (39667) | 39667..40188 | + | 522 | WP_013214008.1 | hypothetical protein | - |
| NXZ72_RS29700 (40234) | 40234..40437 | + | 204 | WP_011977813.1 | hypothetical protein | - |
| NXZ72_RS29705 (40467) | 40467..41471 | + | 1005 | WP_011977814.1 | hypothetical protein | - |
| NXZ72_RS29710 (41655) | 41655..42434 | + | 780 | WP_013214009.1 | site-specific integrase | - |
| NXZ72_RS29715 (42480) | 42480..42737 | - | 258 | WP_013214010.1 | hypothetical protein | - |
| NXZ72_RS29720 (42866) | 42866..42979 | - | 114 | WP_014343462.1 | hypothetical protein | - |
| NXZ72_RS29725 (43515) | 43515..44381 | + | 867 | WP_004118283.1 | replication initiation protein | - |
| NXZ72_RS29730 (45491) | 45491..46696 | + | 1206 | WP_011977818.1 | AAA family ATPase | - |
| NXZ72_RS29735 (46696) | 46696..47670 | + | 975 | WP_011977819.1 | ParB family protein | - |
| NXZ72_RS29740 (47752) | 47752..49023 | - | 1272 | WP_013214011.1 | Y-family DNA polymerase | - |
| NXZ72_RS29745 (49023) | 49023..49454 | - | 432 | WP_001568036.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| NXZ72_RS29750 (49861) | 49861..51348 | + | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| NXZ72_RS29755 (51597) | 51597..52568 | + | 972 | WP_004152353.1 | plasmid segregation protein ParM | - |
| NXZ72_RS29760 (52571) | 52571..53242 | + | 672 | WP_013214012.1 | plasmid partitioning/stability family protein | - |
| NXZ72_RS29765 (53305) | 53305..53535 | + | 231 | WP_001568040.1 | hypothetical protein | - |
| NXZ72_RS29770 (53731) | 53731..53900 | + | 170 | Protein_65 | hypothetical protein | - |
| NXZ72_RS29775 (53972) | 53972..54673 | + | 702 | WP_001568041.1 | DNA methylase | - |
| NXZ72_RS29780 (54673) | 54673..54894 | + | 222 | WP_001568042.1 | hypothetical protein | - |
| NXZ72_RS29785 (54904) | 54904..55323 | + | 420 | WP_001568043.1 | DUF1380 domain-containing protein | - |
| NXZ72_RS29790 (55377) | 55377..56144 | + | 768 | WP_013214013.1 | hypothetical protein | - |
| NXZ72_RS29795 (56825) | 56825..57253 | + | 429 | WP_001568045.1 | antirestriction protein | - |
| NXZ72_RS29800 (57296) | 57296..57802 | + | 507 | WP_013214014.1 | antirestriction protein ArdA | - |
| NXZ72_RS29805 (57845) | 57845..58036 | + | 192 | WP_001568047.1 | hypothetical protein | - |
| NXZ72_RS29810 (58224) | 58224..58478 | + | 255 | WP_011977779.1 | DNA polymerase III subunit theta | - |
| NXZ72_RS29815 (58513) | 58513..58833 | + | 321 | WP_001568049.1 | hypothetical protein | - |
| NXZ72_RS29820 (59513) | 59513..59740 | + | 228 | WP_001568050.1 | hypothetical protein | - |
| NXZ72_RS29825 (59832) | 59832..60062 | + | 231 | WP_001568051.1 | hypothetical protein | - |
| NXZ72_RS29830 (60114) | 60114..61469 | + | 1356 | WP_014343515.1 | DUF3560 domain-containing protein | - |
| NXZ72_RS29835 (61517) | 61517..62080 | + | 564 | WP_014343514.1 | methyltransferase | - |
| NXZ72_RS29840 (62913) | 62913..63455 | + | 543 | WP_014343512.1 | single-stranded DNA-binding protein | - |
| NXZ72_RS29845 (63504) | 63504..63752 | + | 249 | WP_001568055.1 | DUF905 domain-containing protein | - |
| NXZ72_RS29850 (63822) | 63822..65879 | + | 2058 | WP_015493064.1 | ParB/RepB/Spo0J family partition protein | - |
| NXZ72_RS29855 (65924) | 65924..66355 | + | 432 | WP_001568057.1 | conjugation system SOS inhibitor PsiB | - |
| NXZ72_RS29860 (66352) | 66352..67080 | + | 729 | WP_001568058.1 | plasmid SOS inhibition protein A | - |
| NXZ72_RS29865 (67077) | 67077..67403 | + | 327 | WP_013023807.1 | hypothetical protein | - |
| NXZ72_RS29870 (67459) | 67459..67833 | + | 375 | WP_014343510.1 | hypothetical protein | - |
| NXZ72_RS29875 (68003) | 68003..68152 | + | 150 | Protein_86 | FlmC family protein | - |
| NXZ72_RS29880 (68103) | 68103..68219 | + | 117 | WP_055313929.1 | type I toxin-antitoxin system Hok family toxin | - |
| NXZ72_RS29885 (68912) | 68912..69184 | + | 273 | WP_040245921.1 | hypothetical protein | - |
| NXZ72_RS29890 (69181) | 69181..69531 | + | 351 | WP_040245917.1 | hypothetical protein | - |
| NXZ72_RS29895 (69546) | 69546..69863 | + | 318 | WP_014343505.1 | hypothetical protein | - |
| NXZ72_RS29900 (70704) | 70704..71060 | + | 357 | WP_014343501.1 | hypothetical protein | - |
| NXZ72_RS29905 (71121) | 71121..71333 | + | 213 | WP_014343500.1 | hypothetical protein | - |
| NXZ72_RS29910 (71344) | 71344..71568 | + | 225 | WP_014343499.1 | hypothetical protein | - |
| NXZ72_RS29915 (71649) | 71649..71969 | + | 321 | WP_014343498.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| NXZ72_RS29920 (71959) | 71959..72237 | + | 279 | WP_004152721.1 | helix-turn-helix transcriptional regulator | - |
| NXZ72_RS29925 (72241) | 72241..72345 | + | 105 | Protein_96 | transcriptional regulator | - |
| NXZ72_RS29930 (73174) | 73174..73995 | + | 822 | WP_004152492.1 | DUF932 domain-containing protein | - |
| NXZ72_RS29935 (74028) | 74028..74357 | + | 330 | WP_013214015.1 | DUF5983 family protein | - |
| NXZ72_RS29940 (74390) | 74390..74875 | - | 486 | WP_014343495.1 | hypothetical protein | VF |
| NXZ72_RS29945 (75266) | 75266..75682 | + | 417 | WP_014343494.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| NXZ72_RS29950 (75882) | 75882..76619 | + | 738 | WP_154244330.1 | conjugal transfer protein TrbJ | - |
| NXZ72_RS29955 (76734) | 76734..76940 | + | 207 | WP_171773970.1 | TraY domain-containing protein | - |
| NXZ72_RS29960 (77002) | 77002..77370 | + | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| NXZ72_RS29965 (77384) | 77384..77689 | + | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| NXZ72_RS29970 (77709) | 77709..78074 | + | 366 | Protein_105 | type IV conjugative transfer system protein TraE | - |
| NXZ72_RS29975 (78129) | 78129..78833 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NXZ72_RS29980 (78858) | 78858..79058 | + | 201 | WP_072354025.1 | hypothetical protein | - |
| NXZ72_RS29985 (79078) | 79078..79824 | + | 747 | WP_000205770.1 | conjugal transfer pilus acetylase TraX | - |
| NXZ72_RS29990 (79879) | 79879..80439 | + | 561 | WP_000139328.1 | fertility inhibition protein FinO | - |
| NXZ72_RS29995 (80571) | 80571..80771 | + | 201 | WP_015059022.1 | hypothetical protein | - |
| NXZ72_RS30000 (81157) | 81157..81756 | + | 600 | WP_032083981.1 | PIN domain-containing protein | - |
| NXZ72_RS30005 (81818) | 81818..82150 | + | 333 | WP_152916585.1 | hypothetical protein | - |
| - (82351) | 82351..82410 | - | 60 | NuclAT_0 | - | Antitoxin Detail |
| - (82351) | 82351..82410 | - | 60 | NuclAT_0 | - | Antitoxin Detail |
| - (82351) | 82351..82410 | - | 60 | NuclAT_0 | - | Antitoxin Detail |
| - (82351) | 82351..82410 | - | 60 | NuclAT_0 | - | Antitoxin Detail |
| NXZ72_RS30010 (82455) | 82455..82604 | + | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| NXZ72_RS30015 (82888) | 82888..83136 | + | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
| NXZ72_RS30020 (83251) | 83251..83435 | + | 185 | Protein_115 | protein CopA/IncA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|