NZ_CP1017271..149214

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 149214 bp
Accession: NZ_CP101727        Location: 1..149214         Organism: Klebsiella pneumoniae strain 150040X1B1       Replicon: plasmid pCTXM65_150040X1B1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NPN21_RS26900 (1) 1..867 + 867 WP_004118283.1 replication initiation protein -
NPN21_RS26905 (1977) 1977..3182 + 1206 WP_011977818.1 AAA family ATPase -
NPN21_RS26910 (3182) 3182..4156 + 975 WP_011977819.1 ParB family protein -
NPN21_RS26915 (4238) 4238..5509 - 1272 WP_013214011.1 Y-family DNA polymerase -
NPN21_RS26920 (5509) 5509..5940 - 432 WP_001568036.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
NPN21_RS26925 (6347) 6347..7834 + 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
NPN21_RS26930 (8083) 8083..9054 + 972 WP_004152353.1 plasmid segregation protein ParM -
NPN21_RS26935 (9057) 9057..9728 + 672 WP_013214012.1 plasmid partitioning/stability family protein -
NPN21_RS26940 (9791) 9791..10021 + 231 WP_001568040.1 hypothetical protein -
NPN21_RS26945 (10217) 10217..10386 + 170 Protein_9 hypothetical protein -
NPN21_RS26950 (10458) 10458..11159 + 702 WP_001568041.1 DNA methylase -
NPN21_RS26955 (11159) 11159..11380 + 222 WP_001568042.1 hypothetical protein -
NPN21_RS26960 (11390) 11390..11809 + 420 WP_001568043.1 DUF1380 domain-containing protein -
NPN21_RS26965 (11863) 11863..12630 + 768 WP_013214013.1 hypothetical protein -
NPN21_RS26970 (13311) 13311..13739 + 429 WP_001568045.1 antirestriction protein -
NPN21_RS26975 (13782) 13782..14288 + 507 WP_013214014.1 antirestriction protein ArdA -
NPN21_RS26980 (14331) 14331..14522 + 192 WP_001568047.1 hypothetical protein -
NPN21_RS26985 (14710) 14710..14964 + 255 WP_011977779.1 DNA polymerase III subunit theta -
NPN21_RS26990 (14999) 14999..15319 + 321 WP_001568049.1 hypothetical protein -
NPN21_RS26995 (15999) 15999..16226 + 228 WP_001568050.1 hypothetical protein -
NPN21_RS27000 (16318) 16318..16548 + 231 WP_001568051.1 hypothetical protein -
NPN21_RS27005 (16600) 16600..17955 + 1356 WP_014343515.1 DUF3560 domain-containing protein -
NPN21_RS27010 (18003) 18003..18566 + 564 WP_014343514.1 methyltransferase -
NPN21_RS27015 (19398) 19398..19940 + 543 WP_072354024.1 single-stranded DNA-binding protein -
NPN21_RS27020 (19989) 19989..20237 + 249 WP_001568055.1 DUF905 domain-containing protein -
NPN21_RS27025 (20307) 20307..22364 + 2058 WP_015493064.1 ParB/RepB/Spo0J family partition protein -
NPN21_RS27030 (22409) 22409..22840 + 432 WP_001568057.1 conjugation system SOS inhibitor PsiB -
NPN21_RS27035 (22837) 22837..23565 + 729 WP_001568058.1 plasmid SOS inhibition protein A -
NPN21_RS27040 (23562) 23562..23888 + 327 WP_013023807.1 hypothetical protein -
NPN21_RS27045 (23944) 23944..24318 + 375 WP_014343510.1 hypothetical protein -
NPN21_RS27050 (24488) 24488..24637 + 150 Protein_30 FlmC family protein -
NPN21_RS27055 (24588) 24588..24704 + 117 WP_055313929.1 type I toxin-antitoxin system Hok family toxin -
NPN21_RS27060 (25397) 25397..25669 + 273 WP_040245921.1 hypothetical protein -
NPN21_RS27065 (25666) 25666..26016 + 351 WP_040245917.1 hypothetical protein -
NPN21_RS27070 (26031) 26031..26348 + 318 WP_014343505.1 hypothetical protein -
NPN21_RS27075 (27189) 27189..27545 + 357 WP_014343501.1 hypothetical protein -
NPN21_RS27080 (27606) 27606..27818 + 213 WP_014343500.1 hypothetical protein -
NPN21_RS27085 (27829) 27829..28053 + 225 WP_014343499.1 hypothetical protein -
NPN21_RS27090 (28134) 28134..28454 + 321 WP_014343498.1 type II toxin-antitoxin system RelE/ParE family toxin -
NPN21_RS27095 (28444) 28444..28722 + 279 WP_004152721.1 helix-turn-helix transcriptional regulator -
NPN21_RS27100 (28726) 28726..28830 + 105 Protein_40 transcriptional regulator -
NPN21_RS27105 (29659) 29659..30480 + 822 WP_004152492.1 DUF932 domain-containing protein -
NPN21_RS27110 (30513) 30513..30842 + 330 WP_013214015.1 DUF5983 family protein -
NPN21_RS27115 (30875) 30875..31360 - 486 WP_014343495.1 hypothetical protein VF
NPN21_RS27120 (31751) 31751..32167 + 417 WP_014343494.1 conjugal transfer relaxosome DNA-binding protein TraM -
NPN21_RS27125 (32367) 32367..33104 + 738 WP_013214018.1 conjugal transfer protein TrbJ -
NPN21_RS27130 (33219) 33219..33425 + 207 WP_171773970.1 TraY domain-containing protein -
NPN21_RS27135 (33487) 33487..33855 + 369 WP_004194426.1 type IV conjugative transfer system pilin TraA -
NPN21_RS27140 (33869) 33869..34174 + 306 WP_004144424.1 type IV conjugative transfer system protein TraL -
NPN21_RS27145 (34194) 34194..34559 + 366 Protein_49 type IV conjugative transfer system protein TraE -
NPN21_RS27150 (34614) 34614..35318 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
NPN21_RS27155 (35614) 35614..36311 + 698 WP_223174630.1 IS1 family transposase ISKpn14 Transposase
NPN21_RS27160 (36340) 36340..36612 + 273 Protein_52 IS5 family transposase ISPan1 Transposase
NPN21_RS27165 (36892) 36892..37896 - 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
NPN21_RS27170 (37975) 37975..40941 - 2967 WP_042863651.1 Tn3 family transposase TnpA_ISPa38 Transposase
NPN21_RS27175 (40944) 40944..41009 - 66 Protein_55 helix-turn-helix domain-containing protein -
NPN21_RS27180 (41062) 41062..41766 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
NPN21_RS27185 (41791) 41791..41991 + 201 WP_072354025.1 hypothetical protein -
NPN21_RS27190 (42011) 42011..42757 + 747 WP_000205770.1 conjugal transfer pilus acetylase TraX -
NPN21_RS27195 (42812) 42812..43372 + 561 WP_000139328.1 fertility inhibition protein FinO -
NPN21_RS27200 (43504) 43504..43704 + 201 WP_015059022.1 hypothetical protein -
NPN21_RS27205 (44090) 44090..44689 + 600 WP_032083981.1 PIN domain-containing protein -
NPN21_RS27210 (44751) 44751..45083 + 333 WP_152916585.1 hypothetical protein -
- (45284) 45284..45343 - 60 NuclAT_1 - Antitoxin Detail
- (45284) 45284..45343 - 60 NuclAT_1 - Antitoxin Detail
- (45284) 45284..45343 - 60 NuclAT_1 - Antitoxin Detail
- (45284) 45284..45343 - 60 NuclAT_1 - Antitoxin Detail
NPN21_RS27215 (45388) 45388..45537 + 150 WP_001312851.1 Hok/Gef family protein Toxin Detail
NPN21_RS27220 (45821) 45821..46069 + 249 WP_000083837.1 replication regulatory protein RepA -
NPN21_RS27225 (46184) 46184..46362 + 179 Protein_65 protein CopA/IncA -
NPN21_RS27230 (46381) 46381..47238 + 858 WP_032495102.1 incFII family plasmid replication initiator RepA -
NPN21_RS27235 (48177) 48177..48830 + 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
NPN21_RS27240 (48923) 48923..49180 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
NPN21_RS27245 (49113) 49113..49514 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
NPN21_RS27250 (49763) 49763..50178 + 416 Protein_70 IS1 family transposase -
NPN21_RS27255 (50214) 50214..50633 - 420 Protein_71 Tn3 family transposase TnpA_Tn3 Transposase
NPN21_RS27260 (50697) 50697..51401 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
NPN21_RS27265 (51454) 51454..51930 + 477 Protein_73 PAS domain-containing protein -
NPN21_RS27270 (51998) 51998..53095 - 1098 Protein_74 TonB-dependent receptor -
NPN21_RS27275 (53152) 53152..54120 - 969 WP_013362812.1 IS5 family transposase IS903B Transposase
NPN21_RS27280 (54155) 54155..55030 - 876 WP_013188475.1 Beta-lactamase Toho-1 ARG
NPN21_RS27285 (55280) 55280..55471 - 192 Protein_77 IS1380 family transposase -
NPN21_RS27290 (55541) 55541..56245 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
NPN21_RS27295 (56297) 56297..56443 - 147 Protein_79 Tn3 family transposase -
NPN21_RS27300 (56497) 56497..57201 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
NPN21_RS27305 (57271) 57271..57462 + 192 Protein_81 IS1380 family transposase -
NPN21_RS27310 (57712) 57712..58587 + 876 WP_013188475.1 Beta-lactamase Toho-1 ARG
NPN21_RS27315 (58622) 58622..59590 + 969 WP_013362812.1 IS5 family transposase IS903B Transposase
NPN21_RS27320 (59647) 59647..60744 + 1098 Protein_84 TonB-dependent receptor -
NPN21_RS27325 (60812) 60812..61288 - 477 Protein_85 PAS domain-containing protein -
NPN21_RS27330 (61341) 61341..62045 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
NPN21_RS27335 (63625) 63625..63859 + 235 Protein_87 type II toxin-antitoxin system RelE/ParE family toxin -
NPN21_RS27340 (63987) 63987..64268 + 282 WP_001333089.1 hypothetical protein -
NPN21_RS27345 (64391) 64391..64741 - 351 WP_000361389.1 plasmid partitioning/stability family protein -
NPN21_RS27350 (64744) 64744..65706 - 963 WP_000959884.1 plasmid segregation protein ParM -
NPN21_RS27355 (65853) 65853..66146 + 294 WP_032146011.1 hypothetical protein -
NPN21_RS27360 (66223) 66223..66906 + 684 WP_000085883.1 DNA methylase -
NPN21_RS27365 (66907) 66907..67128 + 222 WP_001104881.1 hypothetical protein -
NPN21_RS27370 (67142) 67142..67576 + 435 WP_000274503.1 DUF1380 family protein -
NPN21_RS27375 (67627) 67627..68403 + 777 WP_001383963.1 hypothetical protein -
NPN21_RS27380 (68821) 68821..69246 + 426 WP_001198928.1 antirestriction protein -
NPN21_RS27385 (69293) 69293..69715 + 423 WP_000271762.1 DUF1380 family protein -
NPN21_RS27390 (69712) 69712..69903 + 192 WP_001027493.1 hypothetical protein -
NPN21_RS27395 (70217) 70217..71884 - 1668 WP_012372796.1 group II intron reverse transcriptase/maturase -
NPN21_RS27400 (72613) 72613..72767 - 155 Protein_100 hypothetical protein -
NPN21_RS27405 (73284) 73284..73514 + 231 WP_000218642.1 hypothetical protein -
NPN21_RS27410 (73566) 73566..74927 + 1362 WP_000170695.1 DUF3560 domain-containing protein -
NPN21_RS27415 (74974) 74974..75537 + 564 WP_015059007.1 class I SAM-dependent methyltransferase -
NPN21_RS27420 (75623) 75623..76084 - 462 Protein_104 hypothetical protein -
NPN21_RS27425 (76386) 76386..76913 + 528 WP_000290834.1 single-stranded DNA-binding protein -
NPN21_RS27430 (76971) 76971..77204 + 234 WP_000006003.1 DUF905 family protein -
NPN21_RS27435 (77265) 77265..79288 + 2024 Protein_107 ParB/RepB/Spo0J family partition protein -
NPN21_RS27440 (79357) 79357..79791 + 435 WP_000845953.1 conjugation system SOS inhibitor PsiB -
NPN21_RS27445 (79788) 79788..80507 + 720 WP_001276217.1 plasmid SOS inhibition protein A -
- (80519) 80519..80743 + 225 NuclAT_0 - Antitoxin Detail
- (80519) 80519..80743 + 225 NuclAT_0 - Antitoxin Detail
- (80519) 80519..80743 + 225 NuclAT_0 - Antitoxin Detail
- (80519) 80519..80743 + 225 NuclAT_0 - Antitoxin Detail
NPN21_RS27450 (80729) 80729..80878 + 150 Protein_110 plasmid maintenance protein Mok -
NPN21_RS27455 (80820) 80820..80945 + 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
NPN21_RS27460 (81264) 81264..81560 - 297 Protein_112 hypothetical protein -
NPN21_RS27465 (81860) 81860..82156 + 297 WP_001272251.1 hypothetical protein -
NPN21_RS27470 (82267) 82267..83088 + 822 WP_001234445.1 DUF932 domain-containing protein -
NPN21_RS27475 (83385) 83385..84032 - 648 WP_015059008.1 hypothetical protein VF
NPN21_RS27480 (84309) 84309..84692 + 384 WP_000124981.1 conjugal transfer relaxosome DNA-binding protein TraM -
NPN21_RS27485 (84883) 84883..85569 + 687 WP_015059009.1 PAS domain-containing protein -
NPN21_RS27490 (85663) 85663..85890 + 228 WP_001254386.1 conjugal transfer relaxosome protein TraY -
NPN21_RS27495 (85924) 85924..86289 + 366 WP_021519752.1 type IV conjugative transfer system pilin TraA -
NPN21_RS27500 (86304) 86304..86615 + 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
NPN21_RS27505 (86637) 86637..87203 + 567 WP_000399794.1 type IV conjugative transfer system protein TraE -
NPN21_RS27510 (87190) 87190..87918 + 729 WP_001230787.1 type-F conjugative transfer system secretin TraK -
NPN21_RS27515 (87918) 87918..89345 + 1428 WP_032297072.1 F-type conjugal transfer pilus assembly protein TraB -
NPN21_RS27520 (89335) 89335..89925 + 591 WP_000002778.1 conjugal transfer pilus-stabilizing protein TraP -
NPN21_RS27525 (89912) 89912..90109 + 198 WP_001324648.1 conjugal transfer protein TrbD -
NPN21_RS27530 (90121) 90121..90372 + 252 WP_001038341.1 conjugal transfer protein TrbG -
NPN21_RS27535 (90369) 90369..90884 + 516 WP_062955122.1 type IV conjugative transfer system lipoprotein TraV -
NPN21_RS27540 (91019) 91019..91240 + 222 WP_001278692.1 conjugal transfer protein TraR -
NPN21_RS27545 (91400) 91400..94027 + 2628 WP_015059012.1 type IV secretion system protein TraC -
NPN21_RS27550 (94024) 94024..94410 + 387 WP_015059013.1 type-F conjugative transfer system protein TrbI -
NPN21_RS27555 (94407) 94407..95039 + 633 WP_001203735.1 type-F conjugative transfer system protein TraW -
NPN21_RS27560 (95036) 95036..96028 + 993 WP_000830838.1 conjugal transfer pilus assembly protein TraU -
NPN21_RS27565 (96055) 96055..96363 + 309 WP_000412447.1 hypothetical protein -
NPN21_RS27570 (96426) 96426..96947 + 522 WP_015059014.1 hypothetical protein -
NPN21_RS27575 (96974) 96974..97612 + 639 WP_000087532.1 type-F conjugative transfer system pilin assembly protein TrbC -
NPN21_RS27580 (97609) 97609..97980 + 372 WP_000056336.1 hypothetical protein -
NPN21_RS27585 (98006) 98006..98428 + 423 WP_001229309.1 HNH endonuclease signature motif containing protein -
NPN21_RS27590 (98425) 98425..100275 + 1851 WP_015059015.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
NPN21_RS27595 (100302) 100302..100559 + 258 WP_053913405.1 conjugal transfer protein TrbE -
NPN21_RS27600 (100546) 100546..101295 + 750 WP_072354014.1 type-F conjugative transfer system pilin assembly protein TraF -
NPN21_RS27605 (101456) 101456..101692 + 237 WP_000270010.1 type-F conjugative transfer system pilin chaperone TraQ -
NPN21_RS27610 (101679) 101679..102224 + 546 WP_000059817.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
NPN21_RS27615 (102214) 102214..102528 + 315 WP_001384255.1 P-type conjugative transfer protein TrbJ -
NPN21_RS27620 (102482) 102482..102874 + 393 WP_000126338.1 F-type conjugal transfer protein TrbF -
NPN21_RS27625 (102861) 102861..104234 + 1374 WP_000944325.1 conjugal transfer pilus assembly protein TraH -
NPN21_RS27630 (104231) 104231..107047 + 2817 WP_015059018.1 conjugal transfer mating-pair stabilization protein TraG -
NPN21_RS27635 (107080) 107080..107601 + 522 WP_000632668.1 conjugal transfer entry exclusion protein TraS -
NPN21_RS27640 (107626) 107626..108357 + 732 WP_021559024.1 conjugal transfer complement resistance protein TraT -
NPN21_RS27645 (108560) 108560..109297 + 738 WP_015059020.1 hypothetical protein -
NPN21_RS27650 (109348) 109348..111573 + 2226 WP_000009363.1 type IV conjugative transfer system coupling protein TraD -
NPN21_RS27655 (111573) 111573..116708 + 5136 WP_071177725.1 Multifunctional conjugation protein TraI Relaxase
NPN21_RS27660 (116742) 116742..117446 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
NPN21_RS27665 (117915) 117915..118478 - 564 WP_155082050.1 hypothetical protein -
NPN21_RS27670 (118600) 118600..119142 - 543 WP_077273850.1 restriction endonuclease -
NPN21_RS27675 (119124) 119124..120104 - 981 WP_000019445.1 IS5 family transposase ISKpn26 Transposase
NPN21_RS27680 (120173) 120173..120565 + 393 Protein_156 3'-5' exonuclease -
NPN21_RS27685 (120618) 120618..121013 + 396 WP_015493087.1 hypothetical protein -
NPN21_RS27690 (121010) 121010..121621 + 612 WP_015493086.1 DUF2913 family protein -
NPN21_RS27695 (121618) 121618..122568 - 951 WP_015493085.1 ISNCY family transposase ISRor2 VF
NPN21_RS27700 (122715) 122715..122915 - 201 WP_040219232.1 hypothetical protein -
NPN21_RS27705 (122969) 122969..123601 - 633 WP_022652286.1 Tn3 family transposase TnpR_TnEc1 Transposase
NPN21_RS27710 (123964) 123964..125169 + 1206 WP_015493083.1 Plasmid partition protein A VF
NPN21_RS27715 (125166) 125166..126137 + 972 WP_016479949.1 ParB family protein -
NPN21_RS27720 (126273) 126273..127544 - 1272 WP_015493081.1 Y-family DNA polymerase -
NPN21_RS27725 (127544) 127544..127966 - 423 WP_015493080.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
NPN21_RS27730 (128146) 128146..128817 - 672 WP_015493079.1 SOS response-associated peptidase family protein -
NPN21_RS27735 (129176) 129176..129853 + 678 WP_002211749.1 DNA methylase -
NPN21_RS27740 (129853) 129853..130074 + 222 WP_015493077.1 hypothetical protein -
NPN21_RS27745 (130085) 130085..130504 + 420 WP_015493076.1 DUF1380 family protein -
NPN21_RS27750 (130558) 130558..131337 + 780 WP_015493075.1 hypothetical protein -
NPN21_RS27755 (131742) 131742..132248 + 507 WP_015493074.1 antirestriction protein ArdA -
NPN21_RS27760 (132291) 132291..132482 + 192 WP_015493073.1 hypothetical protein -
NPN21_RS27765 (132675) 132675..132929 + 255 WP_015493072.1 DNA polymerase III subunit theta -
NPN21_RS27770 (132964) 132964..133281 + 318 Protein_174 hypothetical protein -
NPN21_RS27775 (133552) 133552..133622 - 71 Protein_175 hypothetical protein -
NPN21_RS27780 (133907) 133907..134137 + 231 WP_015493071.1 DUF905 domain-containing protein -
NPN21_RS27785 (134208) 134208..136217 + 2010 Protein_177 ParB/RepB/Spo0J family partition protein -
NPN21_RS27790 (136260) 136260..136691 + 432 WP_008324186.1 conjugation system SOS inhibitor PsiB -
NPN21_RS27795 (136688) 136688..137416 + 729 WP_008324185.1 plasmid SOS inhibition protein A -
NPN21_RS27800 (137413) 137413..137736 + 324 WP_008324183.1 hypothetical protein -
NPN21_RS27805 (137798) 137798..138157 + 360 WP_015493069.1 hypothetical protein -
NPN21_RS27810 (138783) 138783..139157 + 375 WP_008324180.1 hypothetical protein -
NPN21_RS27815 (139283) 139283..139987 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
NPN21_RS27820 (140071) 140071..141093 - 1023 WP_000361404.1 helicase UvrD -
NPN21_RS27825 (141078) 141078..142640 - 1563 WP_004206609.1 AAA family ATPase -
NPN21_RS27830 (142714) 142714..143130 - 417 WP_001044770.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
NPN21_RS27835 (143127) 143127..143357 - 231 WP_001261282.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
NPN21_RS27840 (143314) 143314..143775 + 462 WP_014343465.1 hypothetical protein -
NPN21_RS27845 (143936) 143936..144880 + 945 WP_011977810.1 hypothetical protein -
NPN21_RS27850 (144917) 144917..145309 + 393 WP_011977811.1 hypothetical protein -
NPN21_RS27855 (145367) 145367..145888 + 522 WP_013214008.1 hypothetical protein -
NPN21_RS27860 (145934) 145934..146137 + 204 WP_011977813.1 hypothetical protein -
NPN21_RS27865 (146167) 146167..147171 + 1005 WP_011977814.1 hypothetical protein -
NPN21_RS27870 (147355) 147355..148134 + 780 WP_013214009.1 site-specific integrase -
NPN21_RS27875 (148180) 148180..148437 - 258 WP_013214010.1 hypothetical protein -
NPN21_RS27880 (148566) 148566..148679 - 114 WP_014343462.1 hypothetical protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance