MGE detailed information
MGE type: Mobilizable plasmid MGE length: 122859 bp
Accession: NZ_CP101252 Location: 1..122859 Organism: Escherichia coli strain EC21Z-083 Replicon: plasmid pEC21Z083-123K
Accession: NZ_CP101252 Location: 1..122859 Organism: Escherichia coli strain EC21Z-083 Replicon: plasmid pEC21Z083-123K
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NML21_RS22730 (1) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| NML21_RS22735 (1263) | 1263..2003 | - | 741 | WP_001066953.1 | tyrosine-type recombinase/integrase | - |
| NML21_RS22740 (2124) | 2124..2312 | - | 189 | WP_072652414.1 | serine/threonine protein kinase | - |
| NML21_RS22745 (2686) | 2686..3588 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| NML21_RS22750 (3657) | 3657..4766 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| NML21_RS22755 (5199) | 5199..6152 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| NML21_RS22760 (7449) | 7449..7628 | - | 180 | Protein_6 | transposase | - |
| NML21_RS22765 (7767) | 7767..8506 | + | 740 | Protein_7 | IS3 family transposase IS629 | Transposase |
| NML21_RS22770 (9179) | 9179..10687 | + | 1509 | WP_001189111.1 | group II intron reverse transcriptase/maturase | - |
| NML21_RS22775 (10771) | 10771..11250 | + | 480 | Protein_9 | IS3 family transposase IS629 | Transposase |
| NML21_RS22780 (11398) | 11398..11666 | - | 269 | Protein_10 | IS3 family transposase ISLad1 | Transposase |
| NML21_RS22785 (11723) | 11723..12420 | + | 698 | WP_094096600.1 | IS1-like element IS1A family transposase | - |
| NML21_RS22790 (12498) | 12498..13887 | - | 1390 | Protein_12 | ISNCY family transposase ISKpn21 | Transposase |
| NML21_RS22795 (14197) | 14197..14346 | - | 150 | Protein_13 | IS3 family transposase IS2 | Transposase |
| NML21_RS22800 (14524) | 14524..15717 | - | 1194 | WP_000450494.1 | GTP-binding protein | - |
| NML21_RS22810 (18795) | 18795..19088 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| NML21_RS22815 (19146) | 19146..19345 | - | 200 | Protein_17 | lysis protein | - |
| NML21_RS22820 (19545) | 19545..20242 | + | 698 | WP_094096600.1 | IS1-like element IS1A family transposase | - |
| NML21_RS22825 (20259) | 20259..20456 | - | 198 | Protein_19 | colicin V | - |
| NML21_RS22830 (20434) | 20434..20670 | - | 237 | WP_014640552.1 | colicin V immunity protein | - |
| NML21_RS22835 (21159) | 21159..21856 | + | 698 | WP_223369285.1 | IS1-like element IS1A family transposase | - |
| NML21_RS22840 (21989) | 21989..22192 | - | 204 | Protein_22 | hypothetical protein | - |
| NML21_RS22845 (22365) | 22365..22532 | + | 168 | Protein_23 | colicin-B | - |
| NML21_RS22850 (22550) | 22550..23077 | - | 528 | WP_205899291.1 | colicin immunity protein | - |
| NML21_RS22855 (23321) | 23321..24136 | + | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| NML21_RS22860 (24186) | 24186..24539 | - | 354 | WP_000864812.1 | colicin M immunity protein | - |
| NML21_RS22865 (24717) | 24717..25508 | - | 792 | WP_000016493.1 | site-specific integrase | - |
| NML21_RS22870 (25505) | 25505..26194 | - | 690 | WP_000796228.1 | hypothetical protein | - |
| NML21_RS22875 (26238) | 26238..26588 | - | 351 | WP_000493379.1 | hypothetical protein | - |
| NML21_RS22880 (27120) | 27120..30935 | - | 3816 | WP_223364258.1 | hypothetical protein | - |
| NML21_RS22885 (31161) | 31161..31346 | + | 186 | Protein_31 | hypothetical protein | - |
| NML21_RS22890 (31364) | 31364..31711 | - | 348 | WP_000142450.1 | DUF6404 family protein | - |
| NML21_RS22895 (32013) | 32013..32495 | - | 483 | WP_001311056.1 | hypothetical protein | - |
| NML21_RS22900 (32612) | 32612..33460 | - | 849 | WP_023154360.1 | 3'-5' exonuclease | - |
| NML21_RS22905 (33506) | 33506..33784 | - | 279 | WP_097309154.1 | type II toxin-antitoxin system toxin YacB | - |
| NML21_RS22910 (33894) | 33894..35645 | - | 1752 | Protein_36 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| NML21_RS22915 (35649) | 35649..36041 | + | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| NML21_RS22920 (36179) | 36179..37063 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| NML21_RS22925 (37095) | 37095..38294 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| NML21_RS22930 (38400) | 38400..39050 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| NML21_RS22935 (39082) | 39082..39324 | - | 243 | WP_000844627.1 | transposase | - |
| NML21_RS22940 (39382) | 39382..40896 | - | 1515 | Protein_42 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| NML21_RS22945 (40962) | 40962..41666 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NML21_RS22950 (41969) | 41969..42844 | + | 876 | WP_001617865.1 | Beta-lactamase CTX-M-97 | ARG |
| NML21_RS22955 (42879) | 42879..43196 | + | 318 | Protein_45 | IS5 family transposase IS903B | Transposase |
| NML21_RS22960 (43456) | 43456..43872 | + | 417 | WP_014839980.1 | Glutathione transferase FosA | ARG |
| NML21_RS22965 (43877) | 43877..44395 | - | 519 | WP_014839979.1 | FidL-like protein | - |
| NML21_RS22970 (44395) | 44395..45141 | - | 747 | WP_071448054.1 | winged helix-turn-helix domain-containing protein | - |
| NML21_RS22975 (45147) | 45147..45851 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NML21_RS22980 (45965) | 45965..46741 | + | 777 | WP_001199192.1 | SPbeta prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| NML21_RS22985 (46970) | 46970..47870 | + | 901 | Protein_51 | phosphotransferase | - |
| NML21_RS22990 (47945) | 47945..48184 | + | 240 | Protein_52 | AAC(3) family N-acetyltransferase | - |
| NML21_RS22995 (48292) | 48292..49044 | - | 753 | WP_000602738.1 | IS6 family transposase ISRle7 | Transposase |
| NML21_RS23000 (49106) | 49106..50629 | + | 1524 | Protein_54 | Tn3 family transposase TnpA_ISRsp12 | Transposase |
| NML21_RS23005 (50689) | 50689..50817 | + | 129 | WP_032073144.1 | hypothetical protein | - |
| NML21_RS23010 (50855) | 50855..51340 | + | 486 | WP_006581703.1 | hypothetical protein | - |
| NML21_RS23020 (52717) | 52717..53532 | + | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| NML21_RS23025 (53619) | 53619..53861 | + | 243 | Protein_59 | phosphoglucosamine mutase | - |
| NML21_RS23030 (54097) | 54097..55590 | - | 1494 | WP_001120888.1 | IS91 family transposase ISVsa3 | Transposase |
| NML21_RS23035 (55702) | 55702..56007 | - | 306 | WP_001255015.1 | HTH-type transcriptional regulator HdfR | VF |
| NML21_RS23040 (56035) | 56035..57249 | - | 1215 | WP_000214122.1 | Bicyclomycin resistance protein | ARG |
| NML21_RS23045 (57466) | 57466..58350 | - | 885 | WP_001447541.1 | DUF3363 domain-containing protein | - |
| NML21_RS23050 (58381) | 58381..59211 | - | 831 | Protein_64 | IS91 family transposase ISVsa3 | Transposase |
| NML21_RS23055 (59275) | 59275..59979 | + | 705 | WP_001067784.1 | IS6 family transposase IS1006 | Transposase |
| NML21_RS23060 (60064) | 60064..60540 | - | 477 | WP_223171565.1 | hypothetical protein | - |
| NML21_RS23065 (60474) | 60474..63425 | - | 2952 | WP_015344976.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| NML21_RS23070 (63428) | 63428..63988 | - | 561 | WP_000147567.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| NML21_RS23075 (64114) | 64114..64464 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| NML21_RS23080 (64667) | 64667..65680 | - | 1014 | WP_000845039.1 | IS91 family transposase ISAzo26 | Transposase |
| NML21_RS23085 (65825) | 65825..66322 | + | 498 | WP_001083725.1 | IS1595 family transposase ISSsu9 | ARG |
| NML21_RS23090 (66434) | 66434..66724 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| NML21_RS23095 (66730) | 66730..67568 | + | 839 | Protein_73 | Streptomycin 3''-adenylyltransferase | ARG |
| NML21_RS23100 (67685) | 67685..68032 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| NML21_RS23105 (68026) | 68026..68358 | + | 333 | Protein_75 | IS6 family transposase IS15 | Transposase |
| NML21_RS23110 (68415) | 68415..69119 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NML21_RS23115 (69248) | 69248..70012 | + | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| NML21_RS23120 (70505) | 70505..71089 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| NML21_RS23125 (71089) | 71089..72327 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| NML21_RS23130 (72324) | 72324..73229 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| NML21_RS23135 (73351) | 73351..74055 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NML21_RS23140 (74120) | 74120..75370 | - | 1251 | Protein_82 | transposase | - |
| NML21_RS23145 (75441) | 75441..76145 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NML21_RS23150 (76448) | 76448..77308 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| NML21_RS23155 (77458) | 77458..77556 | - | 99 | Protein_85 | IS1 family transposase | - |
| NML21_RS23160 (77585) | 77585..78895 | - | 1311 | WP_001262765.1 | DUF262 domain-containing protein | - |
| NML21_RS23165 (79180) | 79180..79581 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| NML21_RS23170 (79514) | 79514..79771 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| NML21_RS23175 (79864) | 79864..80121 | - | 258 | WP_230133887.1 | CPBP family intramembrane metalloprotease | - |
| NML21_RS23180 (80114) | 80114..80506 | - | 393 | WP_000616804.1 | histidine phosphatase family protein | - |
| NML21_RS23185 (81445) | 81445..82302 | - | 858 | WP_000774297.1 | incFII family plasmid replication initiator RepA | - |
| NML21_RS23190 (82295) | 82295..82777 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| NML21_RS23195 (82770) | 82770..82817 | - | 48 | WP_229471593.1 | hypothetical protein | - |
| NML21_RS23200 (82808) | 82808..83059 | + | 252 | WP_223195197.1 | replication protein RepA | - |
| NML21_RS23205 (83076) | 83076..83333 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| NML21_RS23210 (83617) | 83617..83766 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (83810) | 83810..83871 | + | 62 | NuclAT_2 | - | Antitoxin Detail |
| - (83810) | 83810..83871 | + | 62 | NuclAT_2 | - | Antitoxin Detail |
| - (83810) | 83810..83871 | + | 62 | NuclAT_2 | - | Antitoxin Detail |
| - (83810) | 83810..83871 | + | 62 | NuclAT_2 | - | Antitoxin Detail |
| NML21_RS23215 (84127) | 84127..84201 | - | 75 | Protein_97 | endonuclease | - |
| NML21_RS23220 (84447) | 84447..84659 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| NML21_RS23225 (84795) | 84795..85355 | - | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| NML21_RS23230 (85458) | 85458..86210 | - | 753 | Protein_100 | hypothetical protein | VF |
| NML21_RS23235 (86211) | 86211..86384 | - | 174 | Protein_101 | hypothetical protein | VF |
| NML21_RS23240 (86381) | 86381..86632 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| NML21_RS23245 (86644) | 86644..86841 | - | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| NML21_RS23250 (86828) | 86828..87418 | - | 591 | WP_001376242.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| NML21_RS23255 (87408) | 87408..88835 | - | 1428 | WP_000146685.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| NML21_RS23260 (88835) | 88835..89563 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| NML21_RS23265 (89550) | 89550..90116 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| NML21_RS23270 (90138) | 90138..90449 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| NML21_RS23275 (90464) | 90464..90829 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| NML21_RS23280 (90862) | 90862..91263 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| NML21_RS23285 (91356) | 91356..92045 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| NML21_RS23290 (92232) | 92232..92615 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| NML21_RS23295 (92936) | 92936..93538 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| NML21_RS23300 (93835) | 93835..94656 | - | 822 | WP_001234426.1 | DUF932 domain-containing protein | - |
| NML21_RS23305 (94774) | 94774..95061 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| NML21_RS23310 (95086) | 95086..95292 | - | 207 | WP_000547968.1 | hypothetical protein | - |
| NML21_RS23315 (95362) | 95362..95534 | + | 173 | Protein_117 | hypothetical protein | - |
| NML21_RS23320 (95532) | 95532..95762 | - | 231 | WP_071586998.1 | hypothetical protein | - |
| NML21_RS23325 (95982) | 95982..96107 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| NML21_RS23330 (96049) | 96049..96198 | - | 150 | Protein_120 | plasmid maintenance protein Mok | - |
| - (96184) | 96184..96215 | - | 32 | NuclAT_1 | - | Antitoxin Detail |
| - (96184) | 96184..96215 | - | 32 | NuclAT_1 | - | Antitoxin Detail |
| - (96184) | 96184..96215 | - | 32 | NuclAT_1 | - | Antitoxin Detail |
| - (96184) | 96184..96215 | - | 32 | NuclAT_1 | - | Antitoxin Detail |
| - (97657) | 97657..97854 | - | 198 | NuclAT_0 | - | - |
| - (97657) | 97657..97854 | - | 198 | NuclAT_0 | - | - |
| - (97657) | 97657..97854 | - | 198 | NuclAT_0 | - | - |
| - (97657) | 97657..97854 | - | 198 | NuclAT_0 | - | - |
| NML21_RS23340 (97666) | 97666..97854 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| NML21_RS23345 (97823) | 97823..98585 | - | 763 | Protein_123 | plasmid SOS inhibition protein A | - |
| NML21_RS23350 (98582) | 98582..99016 | - | 435 | WP_000845936.1 | conjugation system SOS inhibitor PsiB | - |
| NML21_RS23355 (99071) | 99071..99268 | - | 198 | Protein_125 | hypothetical protein | - |
| NML21_RS23360 (99296) | 99296..99529 | - | 234 | WP_000005987.1 | DUF905 family protein | - |
| NML21_RS23365 (99597) | 99597..100136 | - | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| NML21_RS23370 (100162) | 100162..100368 | - | 207 | WP_000275856.1 | hypothetical protein | - |
| NML21_RS23375 (100438) | 100438..100518 | + | 81 | Protein_129 | hypothetical protein | - |
| NML21_RS23380 (100701) | 100701..100870 | - | 170 | Protein_130 | hypothetical protein | - |
| NML21_RS23385 (101507) | 101507..102478 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| NML21_RS23390 (102478) | 102478..103644 | - | 1167 | WP_001238646.1 | hypothetical protein | VF |
| NML21_RS23400 (105126) | 105126..107327 | - | 2202 | WP_000973520.1 | Ferric aerobactin receptor | VF |
| NML21_RS23405 (107353) | 107353..108686 | - | 1334 | Protein_135 | L-lysine N6-monooxygenase | VF |
| NML21_RS23410 (108683) | 108683..110425 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| NML21_RS23415 (110425) | 110425..111372 | - | 948 | WP_000011910.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| NML21_RS23420 (111373) | 111373..113097 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| NML21_RS23425 (113233) | 113233..114426 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| NML21_RS23430 (114806) | 114806..115186 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| NML21_RS23435 (115527) | 115527..115940 | - | 414 | Protein_141 | phosphopyruvate hydratase | - |
| NML21_RS23440 (115938) | 115938..116195 | + | 258 | Protein_142 | transposase | - |
| NML21_RS23445 (116429) | 116429..117286 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| NML21_RS23450 (117283) | 117283..118140 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| NML21_RS23455 (118137) | 118137..118964 | - | 828 | WP_000983710.1 | Manganese transport system ATP-binding protein MntB | VF |
| NML21_RS23460 (118964) | 118964..119878 | - | 915 | WP_000949005.1 | putative periplasmic iron-binding protein | VF |
| NML21_RS23465 (120234) | 120234..120931 | + | 698 | WP_094096600.1 | IS1-like element IS1A family transposase | - |
| NML21_RS23470 (121111) | 121111..121624 | - | 514 | Protein_148 | DUF4113 domain-containing protein | - |
| NML21_RS23475 (121685) | 121685..121789 | - | 105 | Protein_149 | AAA family ATPase | - |
| NML21_RS23480 (121791) | 121791..122114 | - | 324 | Protein_150 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|