MGE detailed information

MGE type: Conjugative plasmid        MGE length: 65831 bp
Accession: NZ_CP101237        Location: 1..65831         Organism: Escherichia coli strain EC21Z-137       Replicon: plasmid pEC21Z137-66K


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NML24_RS24420 (1) 1..858 + 858 WP_141035014.1 incFII family plasmid replication initiator RepA -
NML24_RS24425 (1822) 1822..2073 + 252 WP_001132900.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin Detail
NML24_RS24430 (2070) 2070..2357 + 288 WP_000222766.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin Detail
NML24_RS24435 (2626) 2626..3114 - 489 Protein_3 IS3 family transposase IS629 Transposase
NML24_RS24440 (3167) 3167..3871 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
NML24_RS24445 (3936) 3936..4592 + 657 Protein_5 IS4 family transposase IS10R Transposase
NML24_RS24450 (4605) 4605..5222 - 618 Protein_6 IS6 family transposase IS15DII Transposase
NML24_RS24455 (5287) 5287..5943 + 657 Protein_7 IS4 family transposase IS10R Transposase
NML24_RS24460 (5956) 5956..6573 - 618 Protein_8 IS6 family transposase IS15DII Transposase
NML24_RS24465 (6564) 6564..7070 + 507 WP_001505085.1 hypothetical protein -
NML24_RS24470 (7067) 7067..7921 + 855 WP_063085737.1 site-specific integrase -
NML24_RS24475 (7995) 7995..8270 - 276 WP_000239529.1 hypothetical protein -
NML24_RS24480 (8264) 8264..8908 - 645 WP_000633913.1 division plane positioning ATPase MipZ -
NML24_RS24485 (9130) 9130..10101 + 972 WP_001103690.1 plasmid segregation protein ParM -
NML24_RS24490 (10106) 10106..10498 + 393 WP_000340829.1 plasmid partitioning/stability family protein -
NML24_RS24495 (10503) 10503..11774 - 1272 WP_000457496.1 Y-family DNA polymerase -
NML24_RS24500 (11774) 11774..12211 - 438 WP_000109071.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
NML24_RS24505 (12208) 12208..12456 - 249 WP_000618110.1 DinI-like family protein -
NML24_RS24510 (12874) 12874..13776 + 903 WP_001302618.1 DUF1281 domain-containing protein -
NML24_RS24515 (13773) 13773..14084 + 312 WP_032317461.1 hypothetical protein -
NML24_RS24520 (14161) 14161..14844 + 684 WP_000086185.1 DNA methylase -
NML24_RS24525 (14845) 14845..15066 + 222 WP_001104879.1 hypothetical protein -
NML24_RS24530 (15047) 15047..15514 + 468 WP_023156300.1 DUF1380 family protein -
NML24_RS24535 (15559) 15559..16329 + 771 WP_001006212.1 hypothetical protein -
NML24_RS24540 (16742) 16742..17167 + 426 WP_001198928.1 antirestriction protein -
NML24_RS24545 (17214) 17214..17636 + 423 WP_000271684.1 DUF1380 family protein -
NML24_RS24550 (17633) 17633..17824 + 192 WP_001027516.1 hypothetical protein -
NML24_RS24555 (18862) 18862..19092 + 231 WP_000218642.1 hypothetical protein -
NML24_RS24560 (19144) 19144..20505 + 1362 WP_000170713.1 DUF3560 domain-containing protein -
NML24_RS24565 (20552) 20552..21115 + 564 WP_001311069.1 class I SAM-dependent methyltransferase -
NML24_RS24570 (21115) 21115..21327 + 213 WP_074154109.1 hypothetical protein -
NML24_RS24575 (21267) 21267..21497 + 231 WP_001380705.1 hypothetical protein -
NML24_RS24580 (21738) 21738..21944 + 207 WP_000547968.1 hypothetical protein -
NML24_RS24585 (21970) 21970..22422 + 453 WP_000290842.1 single-stranded DNA-binding protein -
NML24_RS24590 (22484) 22484..22717 + 234 WP_063085740.1 DUF905 family protein -
NML24_RS24595 (22782) 22782..24740 + 1959 WP_063072993.1 ParB/RepB/Spo0J family partition protein -
NML24_RS24600 (24795) 24795..25229 + 435 WP_000845907.1 conjugation system SOS inhibitor PsiB -
NML24_RS24605 (25226) 25226..25988 + 763 Protein_37 plasmid SOS inhibition protein A -
NML24_RS24610 (25957) 25957..26145 - 189 WP_001299721.1 hypothetical protein -
- (25957) 25957..26181 + 225 NuclAT_0 - -
- (25957) 25957..26181 + 225 NuclAT_0 - -
- (25957) 25957..26181 + 225 NuclAT_0 - -
- (25957) 25957..26181 + 225 NuclAT_0 - -
NML24_RS24615 (26167) 26167..26316 + 150 Protein_39 plasmid maintenance protein Mok -
NML24_RS24620 (26258) 26258..26383 + 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
NML24_RS24625 (26603) 26603..26833 + 231 WP_001426396.1 hypothetical protein -
NML24_RS24630 (26831) 26831..27004 - 174 Protein_42 hypothetical protein -
NML24_RS24635 (27074) 27074..27280 + 207 WP_000547968.1 hypothetical protein -
NML24_RS24640 (27305) 27305..27592 + 288 WP_000107535.1 hypothetical protein -
NML24_RS24645 (27712) 27712..28533 + 822 WP_001234469.1 DUF932 domain-containing protein -
NML24_RS24650 (28830) 28830..29477 - 648 WP_001567347.1 hypothetical protein VF
NML24_RS24655 (29754) 29754..30137 + 384 WP_000124981.1 conjugal transfer relaxosome DNA-binding protein TraM -
NML24_RS24660 (30328) 30328..31014 + 687 WP_000332484.1 PAS domain-containing protein -
NML24_RS24665 (31108) 31108..31335 + 228 WP_001254386.1 conjugal transfer relaxosome protein TraY -
NML24_RS24670 (31369) 31369..31731 + 363 WP_000340279.1 type IV conjugative transfer system pilin TraA -
NML24_RS24675 (31736) 31736..32047 + 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
NML24_RS24680 (32069) 32069..32635 + 567 WP_000399792.1 type IV conjugative transfer system protein TraE -
NML24_RS24685 (32622) 32622..33350 + 729 WP_001230787.1 type-F conjugative transfer system secretin TraK -
NML24_RS24690 (33350) 33350..34777 + 1428 WP_021524689.1 F-type conjugal transfer pilus assembly protein TraB -
NML24_RS24695 (34767) 34767..35339 + 573 WP_000002780.1 conjugal transfer pilus-stabilizing protein TraP -
NML24_RS24700 (35336) 35336..35653 + 318 WP_001057292.1 conjugal transfer protein TrbD -
NML24_RS24705 (35650) 35650..35901 + 252 WP_001038341.1 conjugal transfer protein TrbG -
NML24_RS24710 (35898) 35898..36413 + 516 WP_000809906.1 type IV conjugative transfer system lipoprotein TraV -
NML24_RS24715 (36548) 36548..36769 + 222 WP_001278692.1 conjugal transfer protein TraR -
NML24_RS24720 (36929) 36929..39556 + 2628 WP_001064268.1 type IV secretion system protein TraC -
NML24_RS24725 (39553) 39553..39939 + 387 WP_000214084.1 type-F conjugative transfer system protein TrbI -
NML24_RS24730 (39936) 39936..40568 + 633 WP_001203745.1 type-F conjugative transfer system protein TraW -
NML24_RS24735 (40565) 40565..41557 + 993 WP_000830839.1 conjugal transfer pilus assembly protein TraU -
NML24_RS24740 (41583) 41583..42044 + 462 WP_000277845.1 hypothetical protein -
NML24_RS24745 (42074) 42074..42526 + 453 WP_000069427.1 hypothetical protein -
NML24_RS24750 (42554) 42554..43192 + 639 WP_001104248.1 type-F conjugative transfer system pilin assembly protein TrbC -
NML24_RS24755 (43189) 43189..44997 + 1809 WP_000821821.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
NML24_RS24760 (45024) 45024..45281 + 258 WP_000864325.1 conjugal transfer protein TrbE -
NML24_RS24765 (45274) 45274..46017 + 744 WP_001030378.1 type-F conjugative transfer system pilin assembly protein TraF -
NML24_RS24770 (46033) 46033..46380 + 348 WP_001287893.1 conjugal transfer protein TrbA -
NML24_RS24775 (46499) 46499..46783 + 285 WP_089606832.1 type-F conjugative transfer system pilin chaperone TraQ -
NML24_RS24780 (46770) 46770..47315 + 546 WP_000052618.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
NML24_RS24785 (47245) 47245..47607 + 363 WP_023181029.1 P-type conjugative transfer protein TrbJ -
NML24_RS24790 (47607) 47607..48980 + 1374 WP_001137358.1 conjugal transfer pilus assembly protein TraH -
NML24_RS24795 (48977) 48977..51814 + 2838 WP_113450068.1 conjugal transfer mating-pair stabilization protein TraG -
NML24_RS24800 (51798) 51798..52307 + 510 WP_000628099.1 conjugal transfer entry exclusion protein TraS -
NML24_RS24805 (52342) 52342..53052 + 711 WP_042032882.1 conjugal transfer complement resistance protein TraT -
NML24_RS24810 (53304) 53304..55484 + 2181 WP_254841654.1 type IV conjugative transfer system coupling protein TraD -
NML24_RS24815 (55484) 55484..60754 + 5271 WP_254841655.1 Multifunctional conjugation protein TraI Relaxase
NML24_RS24820 (60774) 60774..61520 + 747 WP_110101897.1 conjugal transfer pilus acetylase TraX -
NML24_RS24825 (61579) 61579..62439 + 861 WP_000704523.1 Quorum-quenching protein AidA VF
NML24_RS24830 (62542) 62542..63102 + 561 WP_000139323.1 fertility inhibition protein FinO -
NML24_RS24835 (63231) 63231..63443 + 213 WP_001309245.1 ANR family transcriptional regulator -
NML24_RS24840 (63688) 63688..64149 + 462 WP_001233838.1 thermonuclease family protein -
NML24_RS24845 (64195) 64195..64404 + 210 WP_001298565.1 hemolysin expression modulator Hha -
NML24_RS24850 (64442) 64442..65032 + 591 WP_000766807.1 DUF2726 domain-containing protein -
NML24_RS24855 (65272) 65272..65529 + 258 WP_000083826.1 replication regulatory protein RepA -
NML24_RS24860 (65633) 65633..65819 + 187 Protein_88 protein CopA/IncA -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance