MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 88826 bp
Accession: NZ_CP101224 Location: 1..88826 Organism: Escherichia coli strain EC21Z-144 Replicon: plasmid pEC21Z144-89K
Accession: NZ_CP101224 Location: 1..88826 Organism: Escherichia coli strain EC21Z-144 Replicon: plasmid pEC21Z144-89K
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NML25_RS25525 (1301) | 1301..2041 | - | 741 | WP_254825278.1 | tyrosine-type recombinase/integrase | - |
| NML25_RS25530 (2162) | 2162..2350 | - | 189 | WP_032147349.1 | hypothetical protein | - |
| NML25_RS25535 (2717) | 2717..3886 | + | 1170 | WP_001072358.1 | hypothetical protein | - |
| NML25_RS25540 (4112) | 4112..4287 | - | 176 | Protein_4 | IS3 family transposase | - |
| NML25_RS25545 (4733) | 4733..5005 | - | 273 | WP_001322642.1 | adhesin biosynthesis transcription regulatory family protein | - |
| NML25_RS25550 (5542) | 5542..5966 | - | 425 | Protein_6 | IS3 family transposase IS2 | Transposase |
| NML25_RS25555 (6248) | 6248..8218 | + | 1971 | WP_001298664.1 | Hemin receptor | VF |
| NML25_RS25560 (8225) | 8225..9016 | + | 792 | WP_000977394.1 | DUF4198 domain-containing protein | - |
| NML25_RS25565 (9079) | 9079..9687 | - | 609 | Protein_9 | IS66 family transposase ISEc22 | Transposase |
| NML25_RS25570 (9755) | 9755..10537 | - | 783 | WP_001300609.1 | IS21 family transposase IS100kyp | Transposase |
| NML25_RS25575 (10534) | 10534..11556 | - | 1023 | WP_001310017.1 | IS21 family transposase IS100kyp | Transposase |
| NML25_RS25580 (11642) | 11642..12587 | - | 946 | Protein_12 | IS66 family transposase ISEc8 | Transposase |
| NML25_RS25585 (12636) | 12636..12983 | - | 348 | WP_000612617.1 | IS66 family transposase ISKpn24 | Transposase |
| NML25_RS25590 (12980) | 12980..13384 | - | 405 | WP_016231180.1 | IS66 family transposase ISEc22 | Transposase |
| NML25_RS25595 (13464) | 13464..13802 | - | 339 | Protein_15 | IS3 family transposase IS629 | Transposase |
| NML25_RS25600 (13886) | 13886..15394 | - | 1509 | WP_001189111.1 | group II intron reverse transcriptase/maturase | - |
| NML25_RS25605 (16067) | 16067..16806 | - | 740 | Protein_17 | IS3 family transposase IS629 | Transposase |
| NML25_RS25610 (16908) | 16908..17168 | + | 261 | WP_000371882.1 | hypothetical protein | - |
| NML25_RS25615 (17165) | 17165..17674 | + | 510 | WP_000194542.1 | hypothetical protein | - |
| NML25_RS25620 (17694) | 17694..18041 | - | 348 | WP_000142452.1 | DUF6404 family protein | - |
| NML25_RS25625 (18170) | 18170..18505 | + | 336 | WP_001080732.1 | colicin E1 family microcin immunity protein | - |
| NML25_RS25630 (19957) | 19957..20582 | + | 626 | Protein_22 | replication initiation protein | - |
| NML25_RS25635 (20956) | 20956..21378 | + | 423 | Protein_23 | ChaN family lipoprotein | - |
| NML25_RS25640 (21443) | 21443..22147 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| NML25_RS25645 (22196) | 22196..23101 | - | 906 | Protein_25 | IS4 family transposase IS10R | Transposase |
| NML25_RS25650 (23211) | 23211..24173 | - | 963 | Protein_26 | IS4 family transposase IS10R | Transposase |
| NML25_RS25655 (24316) | 24316..25176 | + | 861 | WP_000557454.1 | SPbeta prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| NML25_RS25660 (25189) | 25189..25293 | + | 105 | Protein_28 | tunicamycin resistance protein | - |
| NML25_RS25665 (25345) | 25345..26049 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| NML25_RS25670 (26348) | 26348..27208 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| NML25_RS25675 (27358) | 27358..27456 | - | 99 | Protein_31 | IS1 family transposase | - |
| NML25_RS25680 (27485) | 27485..28795 | - | 1311 | WP_001262765.1 | DUF262 domain-containing protein | - |
| NML25_RS25685 (29080) | 29080..29481 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| NML25_RS25690 (29414) | 29414..29671 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| NML25_RS25695 (29764) | 29764..30417 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| NML25_RS25700 (30515) | 30515..30655 | - | 141 | WP_001333237.1 | hypothetical protein | - |
| NML25_RS25705 (31357) | 31357..32205 | - | 849 | WP_139471275.1 | incFII family plasmid replication initiator RepA | - |
| NML25_RS25710 (32198) | 32198..32272 | - | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| NML25_RS25715 (32272) | 32272..32403 | - | 132 | Protein_39 | protein CopA/IncA | - |
| NML25_RS25720 (32509) | 32509..32763 | - | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| NML25_RS25725 (33060) | 33060..33194 | - | 135 | WP_023144756.1 | Hok/Gef family protein | Toxin Detail |
| - (33239) | 33239..33299 | + | 61 | NuclAT_0 | - | Antitoxin Detail |
| - (33239) | 33239..33299 | + | 61 | NuclAT_0 | - | Antitoxin Detail |
| - (33239) | 33239..33299 | + | 61 | NuclAT_0 | - | Antitoxin Detail |
| - (33239) | 33239..33299 | + | 61 | NuclAT_0 | - | Antitoxin Detail |
| NML25_RS25730 (33266) | 33266..33552 | - | 287 | Protein_42 | DUF2726 domain-containing protein | - |
| NML25_RS25735 (34065) | 34065..34277 | - | 213 | WP_013023861.1 | hypothetical protein | - |
| NML25_RS25740 (34408) | 34408..34968 | - | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| NML25_RS25745 (35023) | 35023..35769 | - | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| NML25_RS25750 (35789) | 35789..41059 | - | 5271 | WP_233304592.1 | Multifunctional conjugation protein TraI | Relaxase |
| NML25_RS25755 (41059) | 41059..43257 | - | 2199 | WP_024623315.1 | type IV conjugative transfer system coupling protein TraD | - |
| NML25_RS25760 (43254) | 43254..44033 | - | 780 | WP_000199914.1 | hypothetical protein | - |
| NML25_RS25765 (44236) | 44236..44946 | - | 711 | WP_064754955.1 | conjugal transfer complement resistance protein TraT | - |
| NML25_RS25770 (44999) | 44999..45496 | - | 498 | WP_000605862.1 | entry exclusion protein | - |
| NML25_RS25775 (45515) | 45515..48334 | - | 2820 | WP_001007062.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| NML25_RS25780 (48331) | 48331..49704 | - | 1374 | WP_000944328.1 | conjugal transfer pilus assembly protein TraH | - |
| NML25_RS25785 (49691) | 49691..50083 | - | 393 | WP_000659962.1 | F-type conjugal transfer protein TrbF | - |
| NML25_RS25790 (50064) | 50064..50411 | - | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| NML25_RS25795 (50341) | 50341..50886 | - | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| NML25_RS25800 (50873) | 50873..51157 | - | 285 | WP_001617873.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| NML25_RS25805 (51284) | 51284..51604 | - | 321 | WP_001348757.1 | conjugal transfer protein TrbA | - |
| NML25_RS25815 (52586) | 52586..52873 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| NML25_RS25820 (52898) | 52898..53104 | - | 207 | WP_000275859.1 | hypothetical protein | - |
| NML25_RS25825 (53174) | 53174..53347 | + | 174 | Protein_61 | hypothetical protein | - |
| NML25_RS25830 (54076) | 54076..55743 | + | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
| NML25_RS25835 (55856) | 55856..56023 | + | 168 | Protein_63 | hypothetical protein | - |
| NML25_RS25840 (56108) | 56108..56671 | - | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| NML25_RS25845 (56719) | 56719..58080 | - | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| NML25_RS25850 (58132) | 58132..58362 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| NML25_RS25855 (58876) | 58876..59030 | + | 155 | Protein_67 | hypothetical protein | - |
| NML25_RS25860 (59759) | 59759..61426 | + | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
| NML25_RS25865 (61740) | 61740..61931 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| NML25_RS25870 (61928) | 61928..62350 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| NML25_RS25875 (62397) | 62397..62822 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| NML25_RS25880 (63239) | 63239..64015 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| NML25_RS25885 (64066) | 64066..64584 | - | 519 | WP_123325260.1 | DUF1380 family protein | - |
| NML25_RS25890 (64514) | 64514..64735 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| NML25_RS25895 (64736) | 64736..65419 | - | 684 | WP_000086147.1 | DNA methylase | - |
| NML25_RS25900 (65496) | 65496..65807 | - | 312 | WP_032072582.1 | hypothetical protein | - |
| NML25_RS25905 (65804) | 65804..66706 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| NML25_RS25910 (67573) | 67573..68544 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| NML25_RS25915 (68544) | 68544..69710 | - | 1167 | WP_000772446.1 | hypothetical protein | VF |
| NML25_RS25920 (70298) | 70298..71053 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| NML25_RS25925 (71827) | 71827..72633 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| NML25_RS25930 (72634) | 72634..72939 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| NML25_RS25935 (72941) | 72941..73159 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| NML25_RS25940 (73867) | 73867..74862 | + | 996 | WP_000246635.1 | hypothetical protein | - |
| NML25_RS25945 (74866) | 74866..75798 | + | 933 | WP_000991831.1 | S-4TM family putative pore-forming effector | - |
| NML25_RS25950 (76096) | 76096..77184 | + | 1089 | WP_000952231.1 | hypothetical protein | - |
| NML25_RS25955 (77186) | 77186..78055 | + | 870 | WP_001586225.1 | hypothetical protein | - |
| NML25_RS25960 (78112) | 78112..79677 | - | 1566 | WP_001586226.1 | AAA family ATPase | - |
| NML25_RS25965 (79964) | 79964..80476 | + | 513 | WP_016238493.1 | hypothetical protein | - |
| NML25_RS25970 (80510) | 80510..81643 | - | 1134 | WP_000545985.1 | DUF3800 domain-containing protein | - |
| NML25_RS25975 (81810) | 81810..82199 | - | 390 | WP_001403960.1 | hypothetical protein | - |
| NML25_RS25980 (82145) | 82145..82582 | - | 438 | WP_016238492.1 | hypothetical protein | - |
| NML25_RS25985 (82595) | 82595..83096 | - | 502 | Protein_93 | HEPN family nuclease | - |
| NML25_RS25990 (83487) | 83487..86108 | + | 2622 | WP_016238490.1 | hypothetical protein | - |
| NML25_RS25995 (86307) | 86307..86537 | + | 231 | WP_016238489.1 | type II toxin-antitoxin system VapB family antitoxin | - |
| NML25_RS26000 (86534) | 86534..86850 | + | 317 | Protein_96 | type II toxin-antitoxin system VapC family toxin | - |
| NML25_RS26005 (86906) | 86906..87123 | - | 218 | Protein_97 | transposase | - |
| NML25_RS26010 (87124) | 87124..87654 | - | 531 | WP_000348884.1 | GNAT family N-acetyltransferase | - |
| NML25_RS26015 (87658) | 87658..87927 | - | 270 | WP_016238488.1 | DUF1778 domain-containing protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|