MGE detailed information
MGE type: Conjugative plasmid MGE length: 132724 bp
Accession: NZ_CP095255 Location: 1..132724 Organism: Klebsiella pneumoniae strain 21080937 Replicon: plasmid p21080937_2
Accession: NZ_CP095255 Location: 1..132724 Organism: Klebsiella pneumoniae strain 21080937 Replicon: plasmid p21080937_2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MU320_RS27250 (MU320_27250) | 34..3000 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| MU320_RS27255 (MU320_27255) | 3004..3564 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| MU320_RS27260 (MU320_27260) | 3709..4413 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| MU320_RS27265 (MU320_27265) | 4479..5024 | + | 546 | Protein_3 | Tn3 family transposase TnpA_Tn3 | Transposase |
| MU320_RS27270 (MU320_27270) | 5060..5475 | - | 416 | Protein_4 | IS1-like element IS1B family transposase | - |
| MU320_RS27275 (MU320_27275) | 5724..6125 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| MU320_RS27280 (MU320_27280) | 6058..6315 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| MU320_RS27285 (MU320_27285) | 6408..7061 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| MU320_RS27290 (MU320_27290) | 8000..8857 | - | 858 | WP_032495102.1 | incFII family plasmid replication initiator RepA | - |
| MU320_RS29385 | 8850..8924 | - | 75 | WP_001375168.1 | RepA leader peptide Tap | - |
| MU320_RS27305 (MU320_27305) | 9169..9417 | - | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
| MU320_RS27310 (MU320_27310) | 9527..10231 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| MU320_RS27315 (MU320_27315) | 10295..10831 | - | 537 | Protein_12 | IS91 family transposase ISAzo26 | Transposase |
| MU320_RS27320 (MU320_27320) | 10989..11462 | + | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| MU320_RS27325 (MU320_27325) | 11593..12381 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| MU320_RS27330 (MU320_27330) | 12587..12934 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| MU320_RS27335 (MU320_27335) | 12928..13767 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| MU320_RS27340 (MU320_27340) | 13895..14167 | + | 273 | WP_004883563.1 | hypothetical protein | - |
| MU320_RS27345 (MU320_27345) | 14349..15353 | - | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| MU320_RS27350 (MU320_27350) | 15547..16386 | - | 840 | WP_004212797.1 | aldo/keto reductase | - |
| MU320_RS27355 (MU320_27355) | 16383..16862 | - | 480 | WP_004212799.1 | cyclophilin-like fold protein | - |
| MU320_RS27360 (MU320_27360) | 17000..17164 | + | 165 | Protein_21 | Tn3 family transposase TnpA_TnEc1 | Transposase |
| MU320_RS27365 (MU320_27365) | 17447..17677 | - | 231 | WP_011154571.1 | hypothetical protein | - |
| MU320_RS27370 (MU320_27370) | 17863..19638 | - | 1776 | WP_004212803.1 | ABC transporter permease subunit | - |
| MU320_RS27375 (MU320_27375) | 19657..21183 | - | 1527 | WP_004212804.1 | ABC transporter substrate-binding protein | - |
| MU320_RS27380 (MU320_27380) | 21194..22438 | - | 1245 | WP_004212807.1 | MFS transporter | - |
| MU320_RS27385 (MU320_27385) | 22465..23298 | - | 834 | WP_004212808.1 | Oligopeptide transport ATP-binding protein OppF | VF |
| MU320_RS27390 (MU320_27390) | 23295..24104 | - | 810 | WP_011154569.1 | Oligopeptide transport ATP-binding protein OppD | VF |
| MU320_RS27395 (MU320_27395) | 24540..25022 | - | 483 | Protein_28 | N-carbamoyl-L-amino-acid hydrolase | VF |
| MU320_RS27400 (MU320_27400) | 25409..25555 | + | 147 | WP_004212816.1 | hypothetical protein | - |
| MU320_RS29390 | 25589..25714 | + | 126 | WP_011251267.1 | hypothetical protein | - |
| MU320_RS27405 (MU320_27405) | 25718..26203 | + | 486 | WP_011154565.1 | hypothetical protein | - |
| MU320_RS27410 (MU320_27410) | 26300..27286 | + | 987 | Protein_32 | IS630 family transposase | - |
| MU320_RS27415 (MU320_27415) | 27662..28162 | - | 501 | WP_004212823.1 | transcriptional repressor | - |
| MU320_RS27420 (MU320_27420) | 28307..28708 | + | 402 | WP_004212825.1 | phosphoribosyl-AMP cyclohydrolase | - |
| MU320_RS27425 (MU320_27425) | 28745..29965 | + | 1221 | WP_004212827.1 | zinc metallochaperone GTPase ZigA | - |
| MU320_RS27430 (MU320_27430) | 30234..31088 | - | 855 | WP_193904336.1 | ferrous iron transporter B | - |
| MU320_RS27435 (MU320_27435) | 31201..31626 | + | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| MU320_RS27440 (MU320_27440) | 31623..31973 | + | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| MU320_RS27445 (MU320_27445) | 32004..33617 | + | 1614 | WP_000080193.1 | IS66 family transposase ISEc23 | Transposase |
| MU320_RS27450 (MU320_27450) | 33644..34423 | - | 780 | WP_247186134.1 | FeoB small GTPase domain-containing protein | - |
| MU320_RS27455 (MU320_27455) | 34434..35564 | - | 1131 | WP_094818814.1 | NAD(P)-binding domain-containing protein | - |
| MU320_RS27460 (MU320_27460) | 35635..37016 | - | 1382 | Protein_42 | cysteine--tRNA ligase | - |
| MU320_RS27465 (MU320_27465) | 37096..37548 | - | 453 | WP_011251268.1 | transcriptional repressor | - |
| MU320_RS27470 (MU320_27470) | 37646..38845 | + | 1200 | WP_014599314.1 | GTP-binding protein | - |
| MU320_RS27475 (MU320_27475) | 38916..39338 | + | 423 | WP_004214547.1 | RNA polymerase-binding protein DksA | - |
| MU320_RS27480 (MU320_27480) | 39402..40337 | + | 936 | WP_011251270.1 | GTP cyclohydrolase FolE2 | - |
| MU320_RS27485 (MU320_27485) | 40327..40887 | + | 561 | WP_004214543.1 | carbonate dehydratase | - |
| MU320_RS27490 (MU320_27490) | 41017..41883 | + | 867 | WP_011251271.1 | hypothetical protein | - |
| MU320_RS27495 (MU320_27495) | 41900..42724 | - | 825 | WP_004214540.1 | DUF1460 domain-containing protein | - |
| MU320_RS27500 (MU320_27500) | 43154..43306 | + | 153 | Protein_50 | TGS domain-containing protein | - |
| MU320_RS27505 (MU320_27505) | 43394..44155 | + | 762 | Protein_51 | threonine--tRNA ligase | - |
| MU320_RS27510 (MU320_27510) | 44148..44999 | + | 852 | WP_004214538.1 | M14 family metallocarboxypeptidase | - |
| MU320_RS27515 (MU320_27515) | 44996..46342 | + | 1347 | WP_011154555.1 | dihydroorotase | - |
| MU320_RS27520 (MU320_27520) | 46406..47428 | + | 1023 | WP_004214536.1 | porphobilinogen synthase | - |
| MU320_RS27525 (MU320_27525) | 47603..47998 | + | 396 | Protein_55 | IS3 family transposase ISKpn38 | Transposase |
| MU320_RS27535 (MU320_27535) | 48771..49998 | - | 1228 | Protein_57 | IS3 family transposase ISEc36 | Transposase |
| MU320_RS27540 (MU320_27540) | 50368..50682 | + | 315 | WP_011251273.1 | hypothetical protein | - |
| MU320_RS27545 (MU320_27545) | 50691..51185 | + | 495 | WP_011251274.1 | hypothetical protein | - |
| MU320_RS27550 (MU320_27550) | 51191..51631 | + | 441 | WP_011251275.1 | hypothetical protein | - |
| MU320_RS27555 (MU320_27555) | 52056..53012 | - | 957 | WP_011251280.1 | DsbA family protein | - |
| MU320_RS27560 (MU320_27560) | 53072..53413 | - | 342 | WP_011251281.1 | hypothetical protein | - |
| MU320_RS27565 (MU320_27565) | 53427..53738 | - | 312 | WP_011251282.1 | hypothetical protein | - |
| MU320_RS27570 (MU320_27570) | 53755..54204 | - | 450 | WP_011251283.1 | thioredoxin fold domain-containing protein | - |
| MU320_RS27580 (MU320_27580) | 55038..55475 | + | 438 | Protein_66 | IS3 family transposase ISEc27 | Transposase |
| MU320_RS27585 (MU320_27585) | 55680..55991 | + | 312 | WP_011251285.1 | type II toxin-antitoxin system HigB family toxin | Toxin Detail |
| MU320_RS27590 (MU320_27590) | 55988..56407 | + | 420 | WP_011251286.1 | helix-turn-helix domain-containing protein | Antitoxin Detail |
| MU320_RS27595 (MU320_27595) | 56554..57522 | + | 969 | WP_074428168.1 | IS5 family transposase IS903 | Transposase |
| MU320_RS27600 (MU320_27600) | 57594..57959 | - | 366 | WP_048333448.1 | hypothetical protein | - |
| MU320_RS27605 (MU320_27605) | 57973..58761 | - | 789 | WP_040217257.1 | hypothetical protein | - |
| MU320_RS27610 (MU320_27610) | 58782..59402 | - | 621 | WP_223175004.1 | conjugative transfer protein MobI(A/C) | - |
| MU320_RS27615 (MU320_27615) | 59821..60456 | + | 636 | WP_223171879.1 | hypothetical protein | - |
| MU320_RS27620 (MU320_27620) | 60769..61239 | + | 471 | WP_048333570.1 | hypothetical protein | - |
| MU320_RS27625 (MU320_27625) | 61261..62229 | + | 969 | WP_004225014.1 | IS5 family transposase IS903B | Transposase |
| MU320_RS27630 (MU320_27630) | 62341..62907 | + | 567 | WP_094818822.1 | type I-E CRISPR-associated protein Cas6/Cse3/CasE | - |
| MU320_RS27635 (MU320_27635) | 62910..63872 | + | 963 | WP_004902373.1 | DEAD/DEAH box helicase | - |
| MU320_RS27640 (MU320_27640) | 64016..64339 | + | 324 | WP_004902375.1 | hypothetical protein | - |
| MU320_RS27645 (MU320_27645) | 64488..65176 | + | 689 | Protein_79 | IS1 family transposase | - |
| MU320_RS27650 (MU320_27650) | 65187..65453 | + | 267 | Protein_80 | IS3 family transposase | - |
| MU320_RS27655 (MU320_27655) | 65523..66176 | - | 654 | WP_011251259.1 | class I SAM-dependent methyltransferase | - |
| MU320_RS27660 (MU320_27660) | 66400..67380 | - | 981 | WP_000019473.1 | IS5 family transposase ISKpn26 | Transposase |
| MU320_RS27665 (MU320_27665) | 67920..68553 | + | 634 | Protein_83 | hypothetical protein | VF |
| MU320_RS27670 (MU320_27670) | 68609..68731 | + | 123 | WP_213034833.1 | mucoid phenotype synthesis protein RmpD | - |
| MU320_RS27675 (MU320_27675) | 69084..69485 | + | 402 | WP_214588034.1 | LuxR C-terminal-related transcriptional regulator | - |
| MU320_RS27680 (MU320_27680) | 69558..70460 | + | 903 | WP_004213613.1 | DMT family inner membrane transporter PEG344 | - |
| MU320_RS27685 (MU320_27685) | 70603..70824 | - | 222 | WP_004213615.1 | hypothetical protein | - |
| MU320_RS27690 (MU320_27690) | 70886..73060 | - | 2175 | WP_004213617.1 | Ferric enterobactin receptor | VF |
| MU320_RS27695 (MU320_27695) | 73520..74749 | - | 1230 | WP_004902400.1 | Enterochelin esterase | VF |
| MU320_RS27700 (MU320_27700) | 74854..78498 | - | 3645 | WP_011251260.1 | Multidrug efflux ATP-binding/permease protein | VF |
| MU320_RS27705 (MU320_27705) | 78641..79756 | - | 1116 | WP_004213623.1 | Elloramycin glycosyltransferase ElmGT | VF |
| MU320_RS27710 (MU320_27710) | 79853..80064 | - | 212 | Protein_92 | IS110 family transposase ISCps5 | Transposase |
| MU320_RS27715 (MU320_27715) | 80106..80750 | - | 645 | WP_004213626.1 | ParB N-terminal domain-containing protein | - |
| MU320_RS27720 (MU320_27720) | 80735..81967 | - | 1233 | WP_004213628.1 | phosphoadenosine phosphosulfate reductase | - |
| MU320_RS27725 (MU320_27725) | 82110..82316 | - | 207 | Protein_95 | IS66 family transposase ISEc23 | Transposase |
| MU320_RS27730 (MU320_27730) | 82424..82630 | - | 207 | Protein_96 | IS3 family transposase ISKpn37 | Transposase |
| MU320_RS27735 (MU320_27735) | 82855..83376 | + | 522 | WP_004213635.1 | putative RNA polymerase sigma factor FecI | VF |
| MU320_RS27740 (MU320_27740) | 83373..84326 | + | 954 | Protein_98 | fec operon regulator FecR | - |
| MU320_RS27745 (MU320_27745) | 84413..86529 | + | 2117 | Protein_99 | TonB-dependent Fe(3+) dicitrate receptor FecA | - |
| MU320_RS27750 (MU320_27750) | 86604..86729 | + | 126 | Protein_100 | Fe3+-citrate ABC transporter substrate-binding protein | - |
| MU320_RS27755 (MU320_27755) | 86904..87125 | + | 222 | WP_004213643.1 | DUF2188 domain-containing protein | - |
| MU320_RS27760 (MU320_27760) | 87223..87726 | + | 504 | Protein_102 | DUF4113 domain-containing protein | - |
| MU320_RS27765 (MU320_27765) | 87827..88270 | + | 444 | WP_004026357.1 | DUF2384 domain-containing protein | Antitoxin Detail |
| MU320_RS27770 (MU320_27770) | 88267..88737 | + | 471 | WP_004026354.1 | RES family NAD+ phosphorylase | Toxin Detail |
| MU320_RS27775 (MU320_27775) | 88886..89583 | + | 698 | WP_223175001.1 | IS1 family transposase IS1G | Transposase |
| MU320_RS27780 (MU320_27780) | 90969..91619 | - | 651 | WP_068893702.1 | DUF1173 family protein | - |
| MU320_RS27785 (MU320_27785) | 91652..91918 | - | 267 | WP_223175074.1 | DUF1173 family protein | - |
| MU320_RS27790 (MU320_27790) | 92096..92590 | + | 495 | WP_004212794.1 | thermonuclease family protein | - |
| MU320_RS27795 (MU320_27795) | 92927..93325 | + | 399 | WP_004212796.1 | H-NS family nucleoid-associated regulatory protein | - |
| MU320_RS27800 (MU320_27800) | 93772..94776 | - | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| MU320_RS27805 (MU320_27805) | 95004..96209 | + | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| MU320_RS27810 (MU320_27810) | 96220..96525 | + | 306 | WP_000130000.1 | hypothetical protein | Relaxase |
| MU320_RS27815 (MU320_27815) | 96569..96634 | + | 66 | Protein_113 | EAL domain-containing protein | - |
| MU320_RS27820 (MU320_27820) | 96805..97509 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| MU320_RS27825 (MU320_27825) | 97563..97727 | - | 165 | Protein_115 | TraE/TraK family type IV conjugative transfer system protein | - |
| MU320_RS27830 (MU320_27830) | 97747..98052 | - | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| MU320_RS27835 (MU320_27835) | 98066..98434 | - | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| MU320_RS27840 (MU320_27840) | 98496..98702 | - | 207 | WP_171773970.1 | TraY domain-containing protein | - |
| MU320_RS27845 (MU320_27845) | 98817..99554 | - | 738 | WP_154244330.1 | conjugal transfer protein TrbJ | - |
| MU320_RS27850 (MU320_27850) | 99754..100170 | - | 417 | WP_014343494.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| MU320_RS27855 (MU320_27855) | 100561..101046 | + | 486 | WP_014343495.1 | hypothetical protein | VF |
| MU320_RS27860 (MU320_27860) | 101079..101408 | - | 330 | WP_013214015.1 | DUF5983 family protein | - |
| MU320_RS27865 (MU320_27865) | 101441..102262 | - | 822 | WP_004152492.1 | DUF932 domain-containing protein | - |
| MU320_RS27870 (MU320_27870) | 103091..103195 | - | 105 | Protein_124 | transcriptional regulator | - |
| MU320_RS27875 (MU320_27875) | 103199..103477 | - | 279 | WP_004152721.1 | helix-turn-helix transcriptional regulator | - |
| MU320_RS27880 (MU320_27880) | 103467..103787 | - | 321 | WP_014343498.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| MU320_RS27885 (MU320_27885) | 103868..104092 | - | 225 | WP_014343499.1 | hypothetical protein | - |
| MU320_RS27890 (MU320_27890) | 104103..104315 | - | 213 | WP_014343500.1 | hypothetical protein | - |
| MU320_RS27895 (MU320_27895) | 104376..104732 | - | 357 | WP_014343501.1 | hypothetical protein | - |
| MU320_RS27900 (MU320_27900) | 105573..105890 | - | 318 | WP_014343505.1 | hypothetical protein | - |
| MU320_RS27905 (MU320_27905) | 105905..106255 | - | 351 | WP_040245917.1 | hypothetical protein | - |
| MU320_RS27910 (MU320_27910) | 106252..106524 | - | 273 | WP_040245921.1 | hypothetical protein | - |
| MU320_RS27915 (MU320_27915) | 107217..107336 | - | 120 | WP_159376494.1 | type I toxin-antitoxin system Hok family toxin | - |
| MU320_RS27920 (MU320_27920) | 107281..107433 | - | 153 | WP_004150508.1 | DUF5431 family protein | - |
| MU320_RS27925 (MU320_27925) | 107603..107977 | - | 375 | WP_014343510.1 | hypothetical protein | - |
| MU320_RS27930 (MU320_27930) | 108033..108359 | - | 327 | WP_013023807.1 | hypothetical protein | - |
| MU320_RS27935 (MU320_27935) | 108356..109084 | - | 729 | WP_001568058.1 | plasmid SOS inhibition protein A | - |
| MU320_RS27940 (MU320_27940) | 109081..109512 | - | 432 | WP_001568057.1 | conjugation system SOS inhibitor PsiB | - |
| MU320_RS27945 (MU320_27945) | 109557..111614 | - | 2058 | WP_015493064.1 | ParB/RepB/Spo0J family partition protein | - |
| MU320_RS27950 (MU320_27950) | 111684..111932 | - | 249 | WP_001568055.1 | DUF905 domain-containing protein | - |
| MU320_RS27955 (MU320_27955) | 111981..112523 | - | 543 | WP_014343512.1 | single-stranded DNA-binding protein | - |
| MU320_RS27960 (MU320_27960) | 113356..113919 | - | 564 | WP_014343514.1 | methyltransferase | - |
| MU320_RS27965 (MU320_27965) | 113967..115322 | - | 1356 | WP_014343515.1 | DUF3560 domain-containing protein | - |
| MU320_RS27970 (MU320_27970) | 115374..115604 | - | 231 | WP_001568051.1 | hypothetical protein | - |
| MU320_RS27975 (MU320_27975) | 115696..115923 | - | 228 | WP_001568050.1 | hypothetical protein | - |
| MU320_RS27980 (MU320_27980) | 116603..116923 | - | 321 | WP_001568049.1 | hypothetical protein | - |
| MU320_RS27985 (MU320_27985) | 116958..117212 | - | 255 | WP_011977779.1 | DNA polymerase III subunit theta | - |
| MU320_RS27990 (MU320_27990) | 117400..117591 | - | 192 | WP_001568047.1 | hypothetical protein | - |
| MU320_RS27995 (MU320_27995) | 117634..118140 | - | 507 | WP_013214014.1 | antirestriction protein ArdA | - |
| MU320_RS28000 (MU320_28000) | 118183..118611 | - | 429 | WP_001568045.1 | antirestriction protein | - |
| MU320_RS28005 (MU320_28005) | 119292..120059 | - | 768 | WP_013214013.1 | hypothetical protein | - |
| MU320_RS28010 (MU320_28010) | 120113..120532 | - | 420 | WP_001568043.1 | DUF1380 domain-containing protein | - |
| MU320_RS28015 (MU320_28015) | 120542..120763 | - | 222 | WP_001568042.1 | hypothetical protein | - |
| MU320_RS28020 (MU320_28020) | 120763..121464 | - | 702 | WP_001568041.1 | DNA methylase | - |
| MU320_RS28025 (MU320_28025) | 121536..121705 | - | 170 | Protein_155 | hypothetical protein | - |
| MU320_RS28030 (MU320_28030) | 121901..122131 | - | 231 | WP_001568040.1 | hypothetical protein | - |
| MU320_RS28035 (MU320_28035) | 122194..122865 | - | 672 | WP_013214012.1 | plasmid partitioning/stability family protein | - |
| MU320_RS28040 (MU320_28040) | 122868..123839 | - | 972 | WP_004152353.1 | plasmid segregation protein ParM | - |
| MU320_RS28045 (MU320_28045) | 124088..125575 | - | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| MU320_RS28050 (MU320_28050) | 125982..126413 | + | 432 | WP_001568036.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| MU320_RS28055 (MU320_28055) | 126413..127684 | + | 1272 | WP_013214011.1 | Y-family DNA polymerase | - |
| MU320_RS28060 (MU320_28060) | 127766..128740 | - | 975 | WP_011977819.1 | ParB family protein | - |
| MU320_RS28065 (MU320_28065) | 128740..129945 | - | 1206 | WP_011977818.1 | AAA family ATPase | - |
| MU320_RS28070 (MU320_28070) | 131055..131921 | - | 867 | WP_004118283.1 | replication initiation protein | - |
| MU320_RS28075 (MU320_28075) | 132457..132570 | + | 114 | WP_014343462.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|