MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 100291 bp
Accession: NZ_CP093920 Location: 1..100291 Organism: Escherichia coli strain ST167 Replicon: plasmid pGA_EcoNDM5
Accession: NZ_CP093920 Location: 1..100291 Organism: Escherichia coli strain ST167 Replicon: plasmid pGA_EcoNDM5
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MOO49_RS23305 (1) | 1..858 | + | 858 | WP_242806058.1 | incFII family plasmid replication initiator RepA | - |
| MOO49_RS23310 (1797) | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| MOO49_RS23315 (2543) | 2543..2800 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| MOO49_RS23320 (2733) | 2733..3134 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| MOO49_RS23325 (3271) | 3271..6168 | - | 2898 | WP_001553819.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| MOO49_RS23330 (6263) | 6263..6868 | + | 606 | WP_000509965.1 | Tn3 family transposase TnpR_Tn5403 | Transposase |
| MOO49_RS23335 (6892) | 6892..7641 | - | 750 | Protein_6 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| MOO49_RS23340 (7645) | 7645..8037 | + | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| MOO49_RS23345 (8175) | 8175..8663 | + | 489 | Protein_8 | DMT family transporter | - |
| MOO49_RS23350 (8737) | 8737..9420 | - | 684 | WP_138663954.1 | IS6 family transposase IS26 | Transposase |
| MOO49_RS23355 (9486) | 9486..11001 | + | 1516 | Protein_10 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| MOO49_RS23360 (11043) | 11043..11285 | + | 243 | WP_032140899.1 | hypothetical protein | - |
| MOO49_RS23365 (11317) | 11317..11967 | - | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| MOO49_RS23370 (12073) | 12073..13272 | + | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| MOO49_RS23375 (13304) | 13304..13708 | - | 405 | Protein_14 | EamA family transporter | - |
| MOO49_RS23380 (13771) | 13771..14475 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| MOO49_RS23385 (14530) | 14530..15396 | - | 867 | Protein_16 | IS91 family transposase ISAzo26 | Transposase |
| MOO49_RS23390 (15541) | 15541..16038 | + | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| MOO49_RS23395 (16150) | 16150..16440 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| MOO49_RS23400 (16446) | 16446..17284 | + | 839 | Protein_19 | Streptomycin 3''-adenylyltransferase | ARG |
| MOO49_RS23405 (17401) | 17401..17748 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| MOO49_RS23410 (17742) | 17742..18581 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| MOO49_RS23415 (18986) | 18986..20527 | + | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| MOO49_RS23420 (20840) | 20840..21214 | + | 375 | Protein_23 | protein-disulfide reductase DsbD family protein | - |
| MOO49_RS23425 (21314) | 21314..21871 | + | 558 | Protein_24 | twin-arginine translocation (TAT) pathway signal sequence domain protein | - |
| MOO49_RS23430 (21882) | 21882..22520 | - | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| MOO49_RS23435 (22525) | 22525..22890 | - | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| MOO49_RS23440 (22894) | 22894..23706 | - | 813 | WP_023408309.1 | Metallo-beta-lactamase type 2 | ARG |
| MOO49_RS23445 (23807) | 23807..24100 | - | 294 | Protein_28 | IS30 family transposase | - |
| MOO49_RS23450 (24265) | 24265..24969 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| MOO49_RS23455 (25023) | 25023..26071 | - | 1049 | Protein_30 | IS3 family transposase ISKpn11 | Transposase |
| MOO49_RS23460 (26163) | 26163..26705 | - | 543 | WP_002063889.1 | AAA family ATPase | - |
| MOO49_RS23465 (26718) | 26718..27578 | - | 861 | WP_000557452.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| MOO49_RS23470 (27685) | 27685..28389 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| MOO49_RS23475 (28437) | 28437..29126 | + | 690 | Protein_34 | IS6 family transposase IS6100 | Transposase |
| MOO49_RS23480 (29619) | 29619..30203 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| MOO49_RS23485 (30203) | 30203..31441 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| MOO49_RS23490 (31438) | 31438..32343 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| MOO49_RS23495 (32465) | 32465..33167 | - | 703 | Protein_38 | IS6 family transposase IS15DII | Transposase |
| MOO49_RS23500 (33192) | 33192..33566 | + | 375 | WP_162676406.1 | IS66 family transposase ISKpn24 | Transposase |
| MOO49_RS23505 (33615) | 33615..34560 | + | 946 | Protein_40 | IS66 family transposase ISEc8 | Transposase |
| MOO49_RS23510 (34645) | 34645..35668 | + | 1024 | Protein_41 | IS21 family transposase IS100kyp | Transposase |
| MOO49_RS23515 (35665) | 35665..36445 | + | 781 | Protein_42 | IS21-like element IS100kyp family helper ATPase IstB | - |
| MOO49_RS23520 (36513) | 36513..37120 | + | 608 | Protein_43 | IS66 family transposase ISEc22 | Transposase |
| MOO49_RS23525 (37183) | 37183..37976 | - | 794 | Protein_44 | DUF4198 domain-containing protein | - |
| MOO49_RS23530 (37983) | 37983..39952 | - | 1970 | Protein_45 | Hemin receptor | VF |
| MOO49_RS23535 (40233) | 40233..40665 | + | 433 | Protein_46 | IS3 family transposase IS2 | Transposase |
| MOO49_RS23540 (41250) | 41250..41471 | + | 222 | WP_242806059.1 | adhesin biosynthesis transcription regulatory family protein | - |
| MOO49_RS23545 (41917) | 41917..42092 | + | 176 | Protein_48 | IS3 family transposase | - |
| MOO49_RS23550 (43924) | 43924..44040 | + | 117 | Protein_49 | serine/threonine protein kinase | - |
| MOO49_RS23555 (44161) | 44161..44901 | + | 741 | WP_151316179.1 | site-specific integrase | - |
| MOO49_RS23560 (45186) | 45186..46161 | - | 976 | Protein_51 | RepB family plasmid replication initiator protein | - |
| MOO49_RS23565 (46906) | 46906..47229 | + | 324 | Protein_52 | IS21 family transposase IS21 | Transposase |
| MOO49_RS23570 (47231) | 47231..47335 | + | 105 | Protein_53 | AAA family ATPase | - |
| MOO49_RS23575 (47396) | 47396..47890 | + | 495 | Protein_54 | DUF4113 domain-containing protein | - |
| MOO49_RS23580 (48086) | 48086..48463 | - | 378 | Protein_55 | IS1 family transposase IS1SD | Transposase |
| MOO49_RS23585 (48483) | 48483..48782 | - | 300 | WP_001340944.1 | IS1-like element transposase | - |
| MOO49_RS23590 (49138) | 49138..50052 | + | 915 | WP_000949005.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| MOO49_RS23595 (50052) | 50052..50879 | + | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| MOO49_RS23600 (50876) | 50876..51733 | + | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| MOO49_RS23605 (51730) | 51730..52587 | + | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| MOO49_RS23610 (52821) | 52821..53078 | - | 258 | Protein_61 | Tn3 family transposase | - |
| MOO49_RS23615 (53076) | 53076..53489 | + | 414 | Protein_62 | phosphopyruvate hydratase | - |
| MOO49_RS23620 (53830) | 53830..54210 | + | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| MOO49_RS23625 (54590) | 54590..55783 | - | 1194 | WP_000095526.1 | MFS transporter | - |
| MOO49_RS23630 (55919) | 55919..57643 | + | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| MOO49_RS23635 (57644) | 57644..58591 | + | 948 | WP_000011908.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| MOO49_RS23640 (58591) | 58591..60333 | + | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| MOO49_RS23645 (60330) | 60330..61663 | + | 1334 | Protein_68 | L-lysine N6-monooxygenase | VF |
| MOO49_RS23650 (61689) | 61689..63890 | + | 2202 | WP_000973519.1 | Ferric aerobactin receptor | VF |
| MOO49_RS23655 (64416) | 64416..65113 | + | 698 | WP_103215986.1 | IS1 family transposase IS1R | Transposase |
| MOO49_RS23660 (65367) | 65367..66389 | - | 1023 | WP_000361402.1 | helicase UvrD | - |
| MOO49_RS23665 (66374) | 66374..67939 | - | 1566 | WP_001128474.1 | AAA family ATPase | - |
| MOO49_RS23670 (68014) | 68014..68430 | - | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| MOO49_RS23675 (68427) | 68427..68657 | - | 231 | WP_001261286.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| MOO49_RS23680 (69217) | 69217..69435 | + | 219 | WP_000813630.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| MOO49_RS23685 (69437) | 69437..69742 | + | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| MOO49_RS23690 (69743) | 69743..70549 | + | 807 | WP_000016970.1 | site-specific integrase | - |
| MOO49_RS23695 (71271) | 71271..72026 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| MOO49_RS23700 (72614) | 72614..73780 | + | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| MOO49_RS23705 (73780) | 73780..74751 | + | 972 | WP_000817031.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| MOO49_RS23710 (75489) | 75489..76391 | + | 903 | Protein_81 | DUF1281 domain-containing protein | - |
| MOO49_RS23715 (76388) | 76388..76698 | + | 311 | Protein_82 | hypothetical protein | - |
| MOO49_RS23720 (76775) | 76775..77458 | + | 684 | WP_242806054.1 | DNA methylase | - |
| MOO49_RS23725 (77459) | 77459..77680 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| MOO49_RS23730 (77610) | 77610..78128 | + | 519 | WP_223349485.1 | DUF1380 family protein | - |
| MOO49_RS23735 (78173) | 78173..78943 | + | 771 | WP_001006251.1 | hypothetical protein | - |
| MOO49_RS23740 (79357) | 79357..79782 | + | 426 | WP_001546490.1 | antirestriction protein | - |
| MOO49_RS23745 (79829) | 79829..80251 | + | 423 | WP_000271685.1 | DUF1380 family protein | - |
| MOO49_RS23750 (80248) | 80248..80418 | + | 171 | WP_086625069.1 | hypothetical protein | - |
| MOO49_RS23755 (80357) | 80357..81133 | + | 777 | WP_086625070.1 | conjugal transfer pilus acetylase TraX | - |
| MOO49_RS23760 (81188) | 81188..81748 | + | 561 | WP_000139363.1 | fertility inhibition protein FinO | - |
| MOO49_RS23765 (81882) | 81882..82094 | + | 213 | WP_005012601.1 | hypothetical protein | - |
| MOO49_RS23770 (82395) | 82395..82484 | - | 90 | Protein_93 | IS1 family transposase | - |
| MOO49_RS23775 (82539) | 82539..83216 | + | 678 | WP_001339397.1 | IS66 family transposase ISCro1 | Transposase |
| MOO49_RS23780 (83216) | 83216..83563 | + | 348 | WP_000624622.1 | IS66 family transposase ISCro1 | Transposase |
| MOO49_RS23785 (83583) | 83583..85154 | + | 1572 | WP_023149734.1 | IS66 family transposase ISCro1 | Transposase |
| MOO49_RS23790 (85192) | 85192..85808 | - | 617 | Protein_97 | IS1-like element IS1A family transposase | - |
| MOO49_RS23795 (85909) | 85909..86091 | + | 183 | WP_000968309.1 | hypothetical protein | - |
| - (86230) | 86230..86291 | - | 62 | NuclAT_0 | - | Antitoxin Detail |
| - (86230) | 86230..86291 | - | 62 | NuclAT_0 | - | Antitoxin Detail |
| - (86230) | 86230..86291 | - | 62 | NuclAT_0 | - | Antitoxin Detail |
| - (86230) | 86230..86291 | - | 62 | NuclAT_0 | - | Antitoxin Detail |
| MOO49_RS23800 (86335) | 86335..86484 | + | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| MOO49_RS23805 (86768) | 86768..87025 | + | 258 | WP_000083833.1 | replication regulatory protein RepA | - |
| MOO49_RS23810 (87261) | 87261..87335 | + | 75 | WP_032336874.1 | RepA leader peptide Tap | - |
| MOO49_RS23815 (87328) | 87328..87774 | + | 447 | Protein_102 | plasmid replication initiator RepA | - |
| MOO49_RS23820 (87774) | 87774..88388 | - | 615 | Protein_103 | VENN motif pre-toxin domain-containing protein | - |
| MOO49_RS23825 (89095) | 89095..90315 | + | 1221 | WP_000410951.1 | arginine deiminase | - |
| MOO49_RS23830 (90326) | 90326..91237 | + | 912 | WP_000440183.1 | carbamate kinase | - |
| MOO49_RS23835 (91322) | 91322..92326 | + | 1005 | WP_086625071.1 | Ornithine carbamoyltransferase | VF |
| MOO49_RS23840 (92374) | 92374..93777 | + | 1404 | WP_000514417.1 | YfcC family protein | - |
| MOO49_RS23845 (93858) | 93858..94337 | + | 480 | WP_001496175.1 | ArgR family transcriptional regulator | - |
| MOO49_RS23850 (94401) | 94401..94742 | - | 342 | Protein_109 | IS66 family transposase IS682 | Transposase |
| MOO49_RS23855 (94694) | 94694..94915 | - | 222 | WP_000080227.1 | hypothetical protein | - |
| MOO49_RS23860 (94946) | 94946..95296 | - | 351 | WP_000624725.1 | IS66 family transposase ISEc47 | Transposase |
| MOO49_RS23865 (95293) | 95293..95649 | - | 357 | WP_000229735.1 | IS66 family transposase ISEc23 | Transposase |
| MOO49_RS25270 (95807) | 95807..96139 | - | 333 | WP_278192618.1 | IS1 family transposase IS1A | Transposase |
| MOO49_RS25275 (96159) | 96159..96458 | - | 300 | WP_278192619.1 | IS1-like element transposase | - |
| MOO49_RS23875 (96491) | 96491..97068 | + | 578 | Protein_115 | DUF2726 domain-containing protein | - |
| MOO49_RS23880 (97481) | 97481..97834 | - | 354 | WP_000005489.1 | hypothetical protein | - |
| MOO49_RS23885 (98306) | 98306..99328 | - | 1023 | WP_000156883.1 | IS110 family transposase ISSm1 | Transposase |
| MOO49_RS23890 (99733) | 99733..99990 | + | 258 | WP_000083821.1 | replication regulatory protein RepA | - |
| MOO49_RS23895 (100094) | 100094..100279 | + | 186 | WP_242806056.1 | plasmid copy control protein CopA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|