MGE detailed information
MGE type: Conjugative plasmid MGE length: 104665 bp
Accession: NZ_CP092974 Location: 1..104665 Organism: Escherichia coli strain WCHEC005215 Replicon: plasmid pCTXM14_005215
Accession: NZ_CP092974 Location: 1..104665 Organism: Escherichia coli strain WCHEC005215 Replicon: plasmid pCTXM14_005215
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MM176_RS23270 (MM176_23295) | 1..858 | + | 858 | WP_000130646.1 | incFII family plasmid replication initiator RepA | - |
| MM176_RS23275 (MM176_23300) | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| MM176_RS23280 (MM176_23305) | 2543..2800 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| MM176_RS23285 (MM176_23310) | 2733..3134 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| MM176_RS23290 (MM176_23315) | 3383..4080 | + | 698 | WP_095033700.1 | IS1-like element IS1B family transposase | - |
| MM176_RS23295 (MM176_23320) | 4187..4621 | - | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| MM176_RS23300 (MM176_23325) | 4693..5043 | + | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| MM176_RS23305 (MM176_23330) | 5057..5332 | + | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| MM176_RS23310 (MM176_23335) | 5368..5790 | + | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| MM176_RS23315 (MM176_23340) | 5842..7536 | + | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| MM176_RS23320 (MM176_23345) | 7554..7916 | + | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| MM176_RS23325 (MM176_23350) | 7913..8149 | + | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| MM176_RS23330 (MM176_23355) | 8185..8853 | + | 669 | WP_001300294.1 | putative signaling protein | VF |
| MM176_RS23335 (MM176_23360) | 8928..10178 | + | 1251 | Protein_13 | transposase | - |
| MM176_RS23340 (MM176_23365) | 10243..10947 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| MM176_RS23345 (MM176_23370) | 11069..11974 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| MM176_RS23350 (MM176_23375) | 11971..13209 | + | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| MM176_RS23355 (MM176_23380) | 13209..13793 | + | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| MM176_RS23360 (MM176_23385) | 14286..15050 | - | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| MM176_RS23365 (MM176_23390) | 15168..15233 | - | 66 | Protein_19 | EAL domain-containing protein | - |
| MM176_RS23370 (MM176_23395) | 15253..15603 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| MM176_RS23375 (MM176_23400) | 15806..16819 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| MM176_RS23380 (MM176_23405) | 16999..17553 | + | 555 | WP_032488579.1 | aminoglycoside N-acetyltransferase AAC(6')-Ib3 | - |
| MM176_RS23385 (MM176_23410) | 17820..19079 | + | 1260 | Protein_23 | hypothetical protein | ARG |
| MM176_RS23390 (MM176_23415) | 19271..19618 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| MM176_RS23395 (MM176_23420) | 19612..19821 | + | 210 | Protein_25 | dihydropteroate synthase | - |
| MM176_RS23400 (MM176_23425) | 20010..21041 | - | 1032 | WP_014342102.1 | Methyl-accepting chemotaxis protein McpQ | VF |
| MM176_RS23405 (MM176_23430) | 21242..21814 | + | 573 | Protein_27 | IS1380 family transposase ISEcp1 | Transposase |
| MM176_RS23410 (MM176_23435) | 21871..22839 | - | 969 | WP_013362812.1 | IS5 family transposase IS903B | Transposase |
| MM176_RS23415 (MM176_23440) | 22874..23749 | - | 876 | WP_001617865.1 | Beta-lactamase CTX-M-97 | ARG |
| MM176_RS23420 (MM176_23445) | 23999..24286 | - | 288 | Protein_30 | IS1380 family transposase ISEcp1 | Transposase |
| MM176_RS23425 (MM176_23450) | 24352..25056 | + | 705 | WP_001067845.1 | IS6 family transposase IS26 | Transposase |
| MM176_RS23430 (MM176_23455) | 25567..25851 | + | 285 | WP_001178089.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| MM176_RS23435 (MM176_23460) | 25851..26126 | + | 276 | WP_000421257.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| MM176_RS23445 (MM176_23470) | 26938..27306 | + | 369 | Protein_35 | colicin-like pore-forming protein | - |
| MM176_RS23450 (MM176_23475) | 27328..27663 | - | 336 | WP_001080730.1 | colicin 1A immunity protein | - |
| MM176_RS23455 (MM176_23480) | 27792..28139 | + | 348 | WP_000142451.1 | DUF6404 family protein | - |
| MM176_RS23460 (MM176_23485) | 28226..28930 | - | 705 | WP_001067845.1 | IS6 family transposase IS26 | Transposase |
| MM176_RS23465 (MM176_23490) | 28955..29479 | + | 525 | WP_050195267.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| MM176_RS23470 (MM176_23495) | 29556..30947 | + | 1392 | WP_000085084.1 | SIR2 family protein | - |
| MM176_RS23475 (MM176_23500) | 30944..33016 | + | 2073 | WP_001084041.1 | DUF87 domain-containing protein | - |
| MM176_RS23480 (MM176_23505) | 33206..33445 | - | 240 | WP_000371884.1 | hypothetical protein | - |
| MM176_RS23485 (MM176_23510) | 33613..34290 | + | 678 | WP_001339397.1 | IS66 family transposase ISCro1 | Transposase |
| MM176_RS23490 (MM176_23515) | 34290..34637 | + | 348 | WP_000624622.1 | IS66 family transposase ISCro1 | Transposase |
| MM176_RS23495 (MM176_23520) | 34657..36228 | + | 1572 | WP_029392005.1 | IS66 family transposase ISCro1 | Transposase |
| MM176_RS23500 (MM176_23525) | 36427..36918 | + | 492 | WP_000528930.1 | HEPN family nuclease | - |
| MM176_RS23505 (MM176_23530) | 36930..37688 | + | 759 | WP_000494510.1 | hypothetical protein | - |
| MM176_RS23510 (MM176_23535) | 37979..39502 | + | 1524 | WP_000921251.1 | hypothetical protein | - |
| MM176_RS23515 (MM176_23540) | 39537..40661 | + | 1125 | WP_000386705.1 | DUF4238 domain-containing protein | - |
| MM176_RS23520 (MM176_23545) | 40661..40951 | + | 291 | WP_000648897.1 | hypothetical protein | - |
| MM176_RS23525 (MM176_23550) | 41524..42525 | + | 1002 | WP_000785695.1 | DUF4238 domain-containing protein | - |
| MM176_RS23530 (MM176_23555) | 42699..43043 | - | 345 | WP_000792769.1 | hypothetical protein | - |
| MM176_RS23535 (MM176_23560) | 43541..43795 | - | 255 | WP_000678528.1 | hypothetical protein | - |
| MM176_RS23540 (MM176_23565) | 43845..44771 | - | 927 | WP_001290414.1 | hypothetical protein | - |
| MM176_RS23545 (MM176_23570) | 45330..45548 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| MM176_RS23550 (MM176_23575) | 45550..45855 | + | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| MM176_RS23555 (MM176_23580) | 45856..46665 | + | 810 | WP_000016963.1 | site-specific integrase | - |
| MM176_RS23560 (MM176_23585) | 46837..47031 | + | 195 | Protein_58 | colicin M immunity protein | - |
| MM176_RS23565 (MM176_23590) | 47087..47784 | + | 698 | WP_223200906.1 | IS1-like element IS1A family transposase | - |
| MM176_RS23570 (MM176_23595) | 47800..48390 | - | 591 | Protein_60 | colicin-like bacteriocin tRNase domain-containing protein | - |
| MM176_RS23575 (MM176_23600) | 48570..48996 | + | 427 | Protein_61 | tyrosine-type recombinase/integrase | - |
| MM176_RS23580 (MM176_23605) | 49188..49463 | - | 276 | WP_000239529.1 | hypothetical protein | - |
| MM176_RS23585 (MM176_23610) | 49457..50101 | - | 645 | WP_000633913.1 | division plane positioning ATPase MipZ | - |
| MM176_RS23590 (MM176_23615) | 50330..51301 | + | 972 | WP_001103697.1 | plasmid segregation protein ParM | - |
| MM176_RS23595 (MM176_23620) | 51306..51698 | + | 393 | WP_000340829.1 | plasmid partitioning/stability family protein | - |
| MM176_RS23600 (MM176_23625) | 51703..52974 | - | 1272 | WP_000457496.1 | Y-family DNA polymerase | - |
| MM176_RS23605 (MM176_23630) | 52974..53411 | - | 438 | WP_000109071.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| MM176_RS23610 (MM176_23635) | 53408..53656 | - | 249 | WP_000618110.1 | DinI-like family protein | - |
| MM176_RS23615 (MM176_23640) | 54074..54976 | + | 903 | WP_001302618.1 | DUF1281 domain-containing protein | - |
| MM176_RS23620 (MM176_23645) | 54980..55285 | + | 306 | WP_032155763.1 | hypothetical protein | - |
| MM176_RS23625 (MM176_23650) | 55361..56044 | + | 684 | WP_000086160.1 | DNA methylase | - |
| MM176_RS23630 (MM176_23655) | 56045..56266 | + | 222 | WP_001104887.1 | hypothetical protein | - |
| MM176_RS23635 (MM176_23660) | 56226..56712 | + | 487 | Protein_73 | DUF1380 family protein | - |
| MM176_RS23640 (MM176_23665) | 56757..57527 | + | 771 | WP_001006225.1 | hypothetical protein | - |
| MM176_RS23645 (MM176_23670) | 57941..58366 | + | 426 | WP_089079046.1 | antirestriction protein | - |
| MM176_RS23650 (MM176_23675) | 58413..58835 | + | 423 | WP_000271762.1 | DUF1380 family protein | - |
| MM176_RS23655 (MM176_23680) | 58832..59023 | + | 192 | WP_001027495.1 | hypothetical protein | - |
| MM176_RS23660 (MM176_23685) | 59390..59544 | - | 155 | Protein_78 | hypothetical protein | - |
| MM176_RS23665 (MM176_23690) | 60061..60291 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| MM176_RS23670 (MM176_23695) | 60343..61704 | + | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| MM176_RS23675 (MM176_23700) | 61751..62314 | + | 564 | WP_001298559.1 | class I SAM-dependent methyltransferase | - |
| MM176_RS23680 (MM176_23705) | 62400..62855 | - | 456 | Protein_82 | hypothetical protein | - |
| MM176_RS23685 (MM176_23710) | 63155..63451 | + | 297 | WP_001272251.1 | hypothetical protein | - |
| MM176_RS23690 (MM176_23715) | 63562..64383 | + | 822 | WP_001234445.1 | DUF932 domain-containing protein | - |
| MM176_RS23695 (MM176_23720) | 64680..65270 | - | 591 | WP_000252683.1 | hypothetical protein | VF |
| MM176_RS23700 (MM176_23725) | 65605..65988 | + | 384 | WP_001354030.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| MM176_RS23705 (MM176_23730) | 66182..66853 | + | 672 | WP_000283561.1 | conjugal transfer transcriptional regulator TraJ | - |
| MM176_RS23710 (MM176_23735) | 66990..67217 | + | 228 | WP_000089263.1 | conjugal transfer relaxosome protein TraY | - |
| MM176_RS23715 (MM176_23740) | 67250..67609 | + | 360 | WP_001098992.1 | type IV conjugative transfer system pilin TraA | - |
| MM176_RS23720 (MM176_23745) | 67624..67935 | + | 312 | WP_000012113.1 | type IV conjugative transfer system protein TraL | - |
| MM176_RS23725 (MM176_23750) | 67957..68523 | + | 567 | WP_000399780.1 | type IV conjugative transfer system protein TraE | - |
| MM176_RS23730 (MM176_23755) | 68510..69238 | + | 729 | WP_001230772.1 | type-F conjugative transfer system secretin TraK | - |
| MM176_RS23735 (MM176_23760) | 69238..70689 | + | 1452 | WP_000146675.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| MM176_RS23740 (MM176_23765) | 70679..71245 | + | 567 | WP_000896599.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| MM176_RS23745 (MM176_23770) | 71232..71552 | + | 321 | WP_001057307.1 | conjugal transfer protein TrbD | - |
| MM176_RS23750 (MM176_23775) | 71549..72064 | + | 516 | WP_094885505.1 | type IV conjugative transfer system lipoprotein TraV | - |
| MM176_RS23755 (MM176_23780) | 72199..72420 | + | 222 | WP_001278683.1 | conjugal transfer protein TraR | - |
| MM176_RS23760 (MM176_23785) | 72456..73424 | + | 969 | WP_000654804.1 | IS5 family transposase IS903B | Transposase |
| MM176_RS23765 (MM176_23790) | 73464..73892 | + | 429 | WP_089438737.1 | hypothetical protein | - |
| MM176_RS23770 (MM176_23795) | 73885..74358 | + | 474 | WP_000549568.1 | hypothetical protein | - |
| MM176_RS23775 (MM176_23800) | 74438..74656 | + | 219 | WP_000556745.1 | hypothetical protein | - |
| MM176_RS23780 (MM176_23805) | 74684..75031 | + | 348 | WP_000836682.1 | hypothetical protein | - |
| MM176_RS23785 (MM176_23810) | 75157..77787 | + | 2631 | WP_000069777.1 | type IV secretion system protein TraC | - |
| MM176_RS23790 (MM176_23815) | 77784..78170 | + | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| MM176_RS23795 (MM176_23820) | 78167..78799 | + | 633 | WP_094885485.1 | type-F conjugative transfer system protein TraW | - |
| MM176_RS23800 (MM176_23825) | 78796..79788 | + | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| MM176_RS23805 (MM176_23830) | 79818..80123 | + | 306 | WP_000224416.1 | hypothetical protein | - |
| MM176_RS23810 (MM176_23835) | 80132..80770 | + | 639 | WP_001080256.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| MM176_RS23815 (MM176_23840) | 80767..82617 | + | 1851 | WP_000821856.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| MM176_RS23820 (MM176_23845) | 82644..82901 | + | 258 | WP_000864353.1 | conjugal transfer protein TrbE | - |
| MM176_RS23825 (MM176_23850) | 82894..83637 | + | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| MM176_RS23830 (MM176_23855) | 83651..83995 | + | 345 | WP_000556796.1 | conjugal transfer protein TrbA | - |
| MM176_RS23835 (MM176_23860) | 84114..84398 | + | 285 | WP_000624194.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| MM176_RS23840 (MM176_23865) | 84385..84930 | + | 546 | WP_000059831.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| MM176_RS23845 (MM176_23870) | 84860..85207 | + | 348 | WP_001309242.1 | P-type conjugative transfer protein TrbJ | - |
| MM176_RS23850 (MM176_23875) | 85188..85580 | + | 393 | WP_000660699.1 | F-type conjugal transfer protein TrbF | - |
| MM176_RS23855 (MM176_23880) | 85567..86940 | + | 1374 | WP_000944331.1 | conjugal transfer pilus assembly protein TraH | - |
| MM176_RS23860 (MM176_23885) | 86937..89759 | + | 2823 | WP_001007039.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| MM176_RS23865 (MM176_23890) | 89775..90260 | + | 486 | WP_000605870.1 | hypothetical protein | - |
| MM176_RS23870 (MM176_23895) | 90309..91040 | + | 732 | WP_000782451.1 | conjugal transfer complement resistance protein TraT | - |
| MM176_RS23875 (MM176_23900) | 91243..91980 | + | 738 | WP_000199905.1 | hypothetical protein | - |
| MM176_RS23880 (MM176_23905) | 92031..94319 | + | 2289 | WP_125097878.1 | Coupling protein TraD | VF |
| MM176_RS23885 (MM176_23910) | 94319..99589 | + | 5271 | WP_000948354.1 | Multifunctional conjugation protein TraI | Relaxase |
| MM176_RS23890 (MM176_23915) | 99609..100355 | + | 747 | WP_000205725.1 | conjugal transfer pilus acetylase TraX | - |
| MM176_RS23895 (MM176_23920) | 100414..101274 | + | 861 | WP_000704523.1 | putative protein YcjY | VF |
| MM176_RS23900 (MM176_23925) | 101377..101937 | + | 561 | WP_000139323.1 | fertility inhibition protein FinO | - |
| MM176_RS23905 (MM176_23930) | 102066..102278 | + | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| MM176_RS23910 (MM176_23935) | 102523..102984 | + | 462 | WP_001233838.1 | thermonuclease family protein | - |
| MM176_RS23915 (MM176_23940) | 103030..103239 | + | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| MM176_RS23920 (MM176_23945) | 103277..103867 | + | 591 | WP_000766807.1 | DUF2726 domain-containing protein | - |
| MM176_RS23925 (MM176_23950) | 104107..104361 | + | 255 | WP_000083830.1 | replication regulatory protein RepA | - |
| MM176_RS23930 (MM176_23955) | 104468..104653 | + | 186 | WP_012615301.1 | plasmid copy control protein CopA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|