MGE detailed information
MGE type: Conjugative plasmid MGE length: 70864 bp
Accession: NZ_CP092254 Location: 1..70864 Organism: Escherichia coli strain ISHS7 Replicon: plasmid pISHS7_2
Accession: NZ_CP092254 Location: 1..70864 Organism: Escherichia coli strain ISHS7 Replicon: plasmid pISHS7_2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MF614_RS23775 (1) | 1..858 | + | 858 | WP_032495102.1 | incFII family plasmid replication initiator RepA | - |
| MF614_RS23780 (1797) | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| MF614_RS23785 (2543) | 2543..2800 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| MF614_RS23790 (2733) | 2733..3134 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| MF614_RS23795 (3419) | 3419..4729 | + | 1311 | WP_001262765.1 | DUF262 domain-containing protein | - |
| MF614_RS23800 (4758) | 4758..4856 | + | 99 | Protein_5 | IS1 family transposase | - |
| MF614_RS23805 (5006) | 5006..5749 | - | 744 | Protein_6 | Beta-lactamase TEM | ARG |
| MF614_RS23810 (5799) | 5799..6503 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| MF614_RS23815 (6550) | 6550..6753 | - | 204 | WP_239371673.1 | hypothetical protein | - |
| MF614_RS23820 (7053) | 7053..7349 | + | 297 | Protein_9 | hypothetical protein | - |
| MF614_RS23825 (7668) | 7668..7793 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| MF614_RS23830 (7735) | 7735..7884 | - | 150 | Protein_11 | plasmid maintenance protein Mok | - |
| MF614_RS23835 (7906) | 7906..8085 | + | 180 | WP_001309233.1 | hypothetical protein | - |
| - (7870) | 7870..8094 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (7870) | 7870..8094 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (7870) | 7870..8094 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (7870) | 7870..8094 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| MF614_RS23840 (8063) | 8063..8825 | - | 763 | Protein_13 | plasmid SOS inhibition protein A | - |
| MF614_RS23845 (8822) | 8822..9256 | - | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| MF614_RS23850 (9325) | 9325..11348 | - | 2024 | Protein_15 | ParB/RepB/Spo0J family partition protein | - |
| MF614_RS23855 (11409) | 11409..11642 | - | 234 | WP_000006003.1 | DUF905 family protein | - |
| MF614_RS23860 (11700) | 11700..12227 | - | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| MF614_RS23865 (12529) | 12529..13008 | + | 480 | Protein_18 | hypothetical protein | - |
| MF614_RS23870 (13094) | 13094..13657 | - | 564 | WP_015059007.1 | class I SAM-dependent methyltransferase | - |
| MF614_RS23875 (13704) | 13704..15065 | - | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| MF614_RS23880 (15117) | 15117..15347 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| MF614_RS23885 (16385) | 16385..16576 | - | 192 | WP_001027493.1 | hypothetical protein | - |
| MF614_RS23890 (16573) | 16573..16995 | - | 423 | WP_000271762.1 | DUF1380 family protein | - |
| MF614_RS23895 (17042) | 17042..17467 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| MF614_RS23900 (17885) | 17885..18661 | - | 777 | WP_001383963.1 | hypothetical protein | - |
| MF614_RS23905 (18712) | 18712..19146 | - | 435 | WP_000274503.1 | DUF1380 family protein | - |
| MF614_RS23910 (19160) | 19160..19381 | - | 222 | WP_001104881.1 | hypothetical protein | - |
| MF614_RS23915 (19382) | 19382..20065 | - | 684 | WP_000085883.1 | DNA methylase | - |
| MF614_RS23920 (20142) | 20142..20435 | - | 294 | WP_032146011.1 | hypothetical protein | - |
| MF614_RS23925 (20582) | 20582..21544 | + | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| MF614_RS23930 (21547) | 21547..21897 | + | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| MF614_RS23935 (22098) | 22098..22301 | - | 204 | Protein_32 | hypothetical protein | - |
| MF614_RS23940 (22429) | 22429..22663 | - | 235 | Protein_33 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| MF614_RS23945 (24112) | 24112..24177 | - | 66 | Protein_34 | IS1 family transposase | - |
| MF614_RS23950 (24243) | 24243..24947 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| MF614_RS23955 (25369) | 25369..26244 | + | 876 | WP_015387340.1 | Beta-lactamase CTX-M-1 | ARG |
| MF614_RS23960 (26291) | 26291..26767 | - | 477 | WP_013023839.1 | WbuC family cupin fold metalloprotein | - |
| MF614_RS23965 (27026) | 27026..27886 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| MF614_RS23970 (28069) | 28069..28248 | - | 180 | Protein_39 | helix-turn-helix domain-containing protein | - |
| MF614_RS23975 (28303) | 28303..29007 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| MF614_RS23980 (29135) | 29135..29890 | - | 756 | WP_012372818.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase | ARG |
| MF614_RS23985 (30060) | 30060..30599 | - | 540 | Protein_42 | class A beta-lactamase | - |
| MF614_RS23990 (30654) | 30654..30869 | - | 216 | Protein_43 | IS6 family transposase IS15DI | Transposase |
| MF614_RS23995 (30932) | 30932..31636 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| MF614_RS24000 (31917) | 31917..32738 | + | 822 | WP_001234445.1 | DUF932 domain-containing protein | - |
| MF614_RS24005 (33035) | 33035..33682 | - | 648 | WP_015059008.1 | hypothetical protein | VF |
| MF614_RS24010 (33959) | 33959..34342 | + | 384 | WP_000124981.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| MF614_RS24015 (34533) | 34533..35219 | + | 687 | WP_015059009.1 | PAS domain-containing protein | - |
| MF614_RS24020 (35313) | 35313..35540 | + | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| MF614_RS24025 (35574) | 35574..35939 | + | 366 | WP_021519752.1 | type IV conjugative transfer system pilin TraA | - |
| MF614_RS24030 (35954) | 35954..36265 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| MF614_RS24035 (36287) | 36287..36853 | + | 567 | WP_000399794.1 | type IV conjugative transfer system protein TraE | - |
| MF614_RS24040 (36840) | 36840..37568 | + | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| MF614_RS24045 (37568) | 37568..38995 | + | 1428 | WP_032297072.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| MF614_RS24050 (38985) | 38985..39575 | + | 591 | WP_000002778.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| MF614_RS24055 (39562) | 39562..39759 | + | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| MF614_RS24060 (39771) | 39771..40022 | + | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
| MF614_RS24065 (40019) | 40019..40534 | + | 516 | WP_000809902.1 | type IV conjugative transfer system lipoprotein TraV | - |
| MF614_RS24070 (40669) | 40669..40890 | + | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| MF614_RS24075 (41050) | 41050..43677 | + | 2628 | WP_015059012.1 | type IV secretion system protein TraC | - |
| MF614_RS24080 (43674) | 43674..44060 | + | 387 | WP_015059013.1 | type-F conjugative transfer system protein TrbI | - |
| MF614_RS24085 (44057) | 44057..44689 | + | 633 | WP_001203735.1 | type-F conjugative transfer system protein TraW | - |
| MF614_RS24090 (44686) | 44686..45678 | + | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| MF614_RS24095 (45705) | 45705..46013 | + | 309 | WP_000412447.1 | hypothetical protein | - |
| MF614_RS24100 (46076) | 46076..46597 | + | 522 | WP_015059014.1 | hypothetical protein | - |
| MF614_RS24105 (46624) | 46624..47262 | + | 639 | WP_000087532.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| MF614_RS24110 (47259) | 47259..47630 | + | 372 | WP_000056336.1 | hypothetical protein | - |
| MF614_RS24115 (47656) | 47656..48078 | + | 423 | WP_001229309.1 | HNH endonuclease signature motif containing protein | - |
| MF614_RS24120 (48075) | 48075..49925 | + | 1851 | WP_015059015.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| MF614_RS24125 (49952) | 49952..50209 | + | 258 | WP_053913405.1 | conjugal transfer protein TrbE | - |
| MF614_RS24130 (50202) | 50202..50945 | + | 744 | WP_015059017.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| MF614_RS24135 (51106) | 51106..51342 | + | 237 | WP_000270010.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| MF614_RS24140 (51329) | 51329..51874 | + | 546 | WP_000059817.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| MF614_RS24145 (51864) | 51864..52178 | + | 315 | WP_001384255.1 | P-type conjugative transfer protein TrbJ | - |
| MF614_RS24150 (52132) | 52132..52524 | + | 393 | WP_000126338.1 | F-type conjugal transfer protein TrbF | - |
| MF614_RS24155 (52511) | 52511..53884 | + | 1374 | WP_000944325.1 | conjugal transfer pilus assembly protein TraH | - |
| MF614_RS24160 (53881) | 53881..56697 | + | 2817 | WP_015059018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| MF614_RS24165 (56730) | 56730..57251 | + | 522 | WP_000632668.1 | conjugal transfer entry exclusion protein TraS | - |
| MF614_RS24170 (57276) | 57276..58007 | + | 732 | WP_021559024.1 | conjugal transfer complement resistance protein TraT | - |
| MF614_RS24175 (58210) | 58210..58947 | + | 738 | WP_015059020.1 | hypothetical protein | - |
| MF614_RS24180 (58998) | 58998..61205 | + | 2208 | WP_021573169.1 | type IV conjugative transfer system coupling protein TraD | - |
| MF614_RS24185 (61205) | 61205..66475 | + | 5271 | WP_061093447.1 | Multifunctional conjugation protein TraI | Relaxase |
| MF614_RS24190 (66495) | 66495..67241 | + | 747 | WP_000205770.1 | conjugal transfer pilus acetylase TraX | - |
| MF614_RS24195 (67296) | 67296..67856 | + | 561 | WP_000139328.1 | fertility inhibition protein FinO | - |
| MF614_RS24200 (67988) | 67988..68188 | + | 201 | WP_015059022.1 | hypothetical protein | - |
| MF614_RS24205 (68574) | 68574..69173 | + | 600 | WP_032083981.1 | PIN domain-containing protein | - |
| MF614_RS24210 (69235) | 69235..69567 | + | 333 | WP_152916585.1 | hypothetical protein | - |
| - (69768) | 69768..69827 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (69768) | 69768..69827 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (69768) | 69768..69827 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (69768) | 69768..69827 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| MF614_RS24215 (69872) | 69872..70021 | + | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| MF614_RS24220 (70305) | 70305..70553 | + | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|