MGE detailed information
MGE type: Conjugative plasmid MGE length: 109860 bp
Accession: NZ_CP091774 Location: 1..109860 Organism: Escherichia coli strain SWYH.B349aT Replicon: plasmid pB349aT_1
Accession: NZ_CP091774 Location: 1..109860 Organism: Escherichia coli strain SWYH.B349aT Replicon: plasmid pB349aT_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| L6V99_RS23455 (1) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| L6V99_RS23460 (1263) | 1263..2003 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| L6V99_RS23465 (2124) | 2124..2312 | - | 189 | WP_001324033.1 | hypothetical protein | - |
| L6V99_RS23470 (2686) | 2686..3588 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| L6V99_RS23475 (3657) | 3657..4766 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| L6V99_RS23480 (5199) | 5199..6152 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| L6V99_RS23485 (7448) | 7448..7627 | - | 180 | Protein_6 | integrase core domain-containing protein | - |
| L6V99_RS23490 (7766) | 7766..8965 | + | 1200 | Protein_7 | IS3 family transposase IS629 | Transposase |
| L6V99_RS23495 (9113) | 9113..9438 | - | 326 | Protein_8 | IS3 family transposase ISLad1 | Transposase |
| L6V99_RS23500 (9484) | 9484..9824 | + | 341 | Protein_9 | IS3 family transposase | - |
| L6V99_RS23505 (10419) | 10419..11606 | + | 1188 | WP_000928804.1 | efflux RND transporter periplasmic adaptor subunit | - |
| L6V99_RS23510 (11603) | 11603..13543 | + | 1941 | WP_000733250.1 | Macrolide export ATP-binding/permease protein MacB | VF |
| L6V99_RS23515 (13547) | 13547..13840 | + | 294 | WP_237878122.1 | hypothetical protein | - |
| L6V99_RS23520 (13874) | 13874..14578 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| L6V99_RS23525 (14652) | 14652..15125 | - | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| L6V99_RS23530 (15283) | 15283..16296 | + | 1014 | WP_000845048.1 | class 1 integron integrase IntI1 | - |
| L6V99_RS23535 (16499) | 16499..16849 | + | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| L6V99_RS23540 (17059) | 17059..17763 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| L6V99_RS23545 (17813) | 17813..18532 | + | 720 | Protein_18 | helicase RepA family protein | - |
| L6V99_RS23550 (18519) | 18519..19370 | + | 852 | WP_000240536.1 | replication protein C, IncQ-type | - |
| L6V99_RS23555 (19678) | 19678..20493 | + | 816 | WP_001043265.1 | Dihydropteroate synthase | ARG |
| L6V99_RS23560 (20554) | 20554..21357 | + | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| L6V99_RS23565 (21357) | 21357..22193 | + | 837 | WP_000480968.1 | hypothetical protein | ARG |
| L6V99_RS23570 (22254) | 22254..22958 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| L6V99_RS23575 (23023) | 23023..24273 | - | 1251 | Protein_24 | transposase | - |
| L6V99_RS23580 (24348) | 24348..25016 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| L6V99_RS23585 (25052) | 25052..25288 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| L6V99_RS23590 (25285) | 25285..25647 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| L6V99_RS23595 (25665) | 25665..27359 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| L6V99_RS23600 (27411) | 27411..27833 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| L6V99_RS23605 (27869) | 27869..28144 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| L6V99_RS23610 (28158) | 28158..28508 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| L6V99_RS23615 (28580) | 28580..29014 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| L6V99_RS23625 (30067) | 30067..30468 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| L6V99_RS23630 (30401) | 30401..30658 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| L6V99_RS23635 (30751) | 30751..31008 | - | 258 | WP_230133887.1 | CPBP family intramembrane metalloprotease | - |
| L6V99_RS23640 (31001) | 31001..31393 | - | 393 | WP_000616804.1 | histidine phosphatase family protein | - |
| L6V99_RS23645 (32332) | 32332..33189 | - | 858 | WP_000774297.1 | incFII family plasmid replication initiator RepA | - |
| L6V99_RS23650 (33182) | 33182..33664 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| L6V99_RS23655 (33657) | 33657..33704 | - | 48 | WP_229471593.1 | hypothetical protein | - |
| L6V99_RS23660 (33695) | 33695..33946 | + | 252 | WP_223195197.1 | replication protein RepA | - |
| L6V99_RS23665 (33963) | 33963..34220 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| L6V99_RS23670 (34504) | 34504..34653 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (34697) | 34697..34758 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (34697) | 34697..34758 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (34697) | 34697..34758 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (34697) | 34697..34758 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| L6V99_RS23675 (35014) | 35014..35088 | - | 75 | Protein_44 | endonuclease | - |
| L6V99_RS23680 (35334) | 35334..35546 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| L6V99_RS23685 (35682) | 35682..36242 | - | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| L6V99_RS23690 (36345) | 36345..37205 | - | 861 | WP_000704514.1 | putative protein YcjY | VF |
| L6V99_RS23695 (37264) | 37264..38010 | - | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| L6V99_RS23700 (38030) | 38030..43300 | - | 5271 | WP_000986962.1 | Multifunctional conjugation protein TraI | Relaxase |
| L6V99_RS23705 (43382) | 43382..43609 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | - |
| L6V99_RS23710 (43609) | 43609..44007 | + | 399 | WP_000911313.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| L6V99_RS23715 (44016) | 44016..46169 | - | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| L6V99_RS23720 (46422) | 46422..47153 | - | 732 | WP_023565183.1 | conjugal transfer complement resistance protein TraT | - |
| L6V99_RS23725 (47185) | 47185..47682 | - | 498 | WP_000605857.1 | entry exclusion protein | - |
| L6V99_RS23730 (47698) | 47698..50520 | - | 2823 | WP_001007018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| L6V99_RS23735 (50517) | 50517..50798 | - | 282 | Protein_56 | conjugal transfer protein TraH | - |
| L6V99_RS23740 (50808) | 50808..51446 | - | 639 | WP_000777700.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| L6V99_RS23745 (51455) | 51455..52447 | - | 993 | WP_000830183.1 | conjugal transfer pilus assembly protein TraU | - |
| L6V99_RS23750 (52444) | 52444..53076 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| L6V99_RS23755 (53073) | 53073..53459 | - | 387 | WP_000099686.1 | type-F conjugative transfer system protein TrbI | - |
| L6V99_RS23760 (53456) | 53456..54181 | - | 726 | Protein_61 | hypothetical protein | - |
| L6V99_RS23765 (54236) | 54236..54940 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| L6V99_RS23770 (55006) | 55006..55185 | + | 180 | Protein_63 | helix-turn-helix domain-containing protein | - |
| L6V99_RS23775 (55368) | 55368..56228 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| L6V99_RS23780 (56377) | 56377..57054 | + | 678 | Protein_65 | IS4 family transposase IS10R | Transposase |
| L6V99_RS23785 (57064) | 57064..57480 | - | 417 | WP_000275180.1 | Transposon Tn10 TetD protein | VF |
| L6V99_RS23790 (57568) | 57568..58161 | + | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| L6V99_RS23795 (58274) | 58274..59479 | - | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| L6V99_RS23800 (59561) | 59561..60184 | + | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| L6V99_RS23805 (60162) | 60162..60848 | - | 687 | WP_001284954.1 | winged helix-turn-helix domain-containing protein | - |
| L6V99_RS23810 (60856) | 60856..61242 | - | 387 | WP_000460653.1 | hypothetical protein | - |
| L6V99_RS23815 (61235) | 61235..61555 | - | 321 | WP_000562367.1 | antibiotic biosynthesis monooxygenase | - |
| L6V99_RS23820 (61999) | 61999..63204 | + | 1206 | WP_000599533.1 | sodium/glutamate symporter | - |
| L6V99_RS23825 (63435) | 63435..63554 | + | 120 | Protein_74 | LysR family transcriptional regulator | - |
| L6V99_RS23830 (63570) | 63570..64778 | - | 1209 | WP_001352368.1 | IS4 family transposase IS10R | Transposase |
| L6V99_RS23835 (64939) | 64939..65598 | + | 660 | WP_000412211.1 | Chloramphenicol acetyltransferase | ARG |
| L6V99_RS23840 (65799) | 65799..66176 | - | 378 | WP_000656305.1 | GNAT family N-acetyltransferase | - |
| L6V99_RS23845 (66243) | 66243..69209 | - | 2967 | WP_001138064.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| L6V99_RS23850 (69212) | 69212..69772 | - | 561 | WP_021532377.1 | recombinase family protein | - |
| L6V99_RS23855 (69812) | 69812..70516 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| L6V99_RS23860 (70583) | 70583..72487 | - | 1905 | Protein_81 | type IV secretion system protein TraC | - |
| L6V99_RS23865 (72647) | 72647..72868 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| L6V99_RS23870 (73003) | 73003..73518 | - | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| L6V99_RS23875 (73515) | 73515..73766 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| L6V99_RS23880 (73778) | 73778..73975 | - | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| L6V99_RS23885 (73962) | 73962..74552 | - | 591 | WP_001376242.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| L6V99_RS23890 (74542) | 74542..75969 | - | 1428 | WP_000146685.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| L6V99_RS23895 (75969) | 75969..76697 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| L6V99_RS23900 (76684) | 76684..77250 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| L6V99_RS23905 (77272) | 77272..77583 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| L6V99_RS23910 (77598) | 77598..77963 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| L6V99_RS23915 (77996) | 77996..78397 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| L6V99_RS23920 (78490) | 78490..79179 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| L6V99_RS23925 (79366) | 79366..79749 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| L6V99_RS23930 (80070) | 80070..80672 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| L6V99_RS23935 (80969) | 80969..81790 | - | 822 | WP_237878124.1 | DUF932 domain-containing protein | - |
| L6V99_RS23940 (81908) | 81908..82195 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| L6V99_RS23945 (82220) | 82220..82426 | - | 207 | WP_000547968.1 | hypothetical protein | - |
| L6V99_RS23950 (82496) | 82496..82668 | + | 173 | Protein_99 | hypothetical protein | - |
| L6V99_RS23955 (82666) | 82666..82896 | - | 231 | WP_071586998.1 | hypothetical protein | - |
| L6V99_RS23960 (83116) | 83116..83241 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| L6V99_RS23965 (83183) | 83183..83332 | - | 150 | Protein_102 | plasmid maintenance protein Mok | - |
| - (83318) | 83318..83542 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (83318) | 83318..83542 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (83318) | 83318..83542 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (83318) | 83318..83542 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| L6V99_RS23970 (83354) | 83354..83542 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| L6V99_RS23975 (83511) | 83511..84273 | - | 763 | Protein_104 | plasmid SOS inhibition protein A | - |
| L6V99_RS23980 (84270) | 84270..84704 | - | 435 | WP_000845936.1 | conjugation system SOS inhibitor PsiB | - |
| L6V99_RS23985 (84759) | 84759..84956 | - | 198 | Protein_106 | hypothetical protein | - |
| L6V99_RS23990 (84984) | 84984..85217 | - | 234 | WP_000005987.1 | DUF905 family protein | - |
| L6V99_RS23995 (85285) | 85285..85824 | - | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| L6V99_RS24000 (85920) | 85920..87133 | + | 1214 | WP_139371347.1 | IS3 family transposase IS629 | Transposase |
| L6V99_RS24005 (87136) | 87136..87369 | - | 234 | WP_185681501.1 | single-stranded DNA-binding protein | - |
| L6V99_RS24010 (87439) | 87439..87519 | + | 81 | Protein_111 | hypothetical protein | - |
| L6V99_RS24015 (87702) | 87702..87871 | - | 170 | Protein_112 | hypothetical protein | - |
| L6V99_RS24020 (88508) | 88508..89479 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| L6V99_RS24025 (89479) | 89479..90645 | - | 1167 | WP_001238646.1 | Sporulation initiation inhibitor protein Soj | VF |
| L6V99_RS24035 (92127) | 92127..94328 | - | 2202 | WP_000973520.1 | Ferric aerobactin receptor | VF |
| L6V99_RS24040 (94354) | 94354..95687 | - | 1334 | Protein_117 | L-lysine N6-monooxygenase | VF |
| L6V99_RS24045 (95684) | 95684..97426 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| L6V99_RS24050 (97426) | 97426..98373 | - | 948 | WP_000011910.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| L6V99_RS24055 (98374) | 98374..100098 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| L6V99_RS24060 (100234) | 100234..101427 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| L6V99_RS24065 (101807) | 101807..102187 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| L6V99_RS24070 (102528) | 102528..102941 | - | 414 | Protein_123 | phosphopyruvate hydratase | - |
| L6V99_RS24075 (102939) | 102939..103196 | + | 258 | Protein_124 | Tn3 family transposase | - |
| L6V99_RS24080 (103430) | 103430..104287 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| L6V99_RS24085 (104284) | 104284..105141 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| L6V99_RS24090 (105138) | 105138..105965 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| L6V99_RS24095 (105965) | 105965..106879 | - | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| L6V99_RS24100 (107235) | 107235..107932 | + | 698 | WP_223155668.1 | IS1 family transposase IS1S | Transposase |
| L6V99_RS24105 (108112) | 108112..108625 | - | 514 | Protein_130 | DUF4113 domain-containing protein | - |
| L6V99_RS24110 (108686) | 108686..108790 | - | 105 | Protein_131 | AAA family ATPase | - |
| L6V99_RS24115 (108792) | 108792..109115 | - | 324 | Protein_132 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|