NZ_CP0913021..161029

MGE detailed information

MGE type: Non-Mobilizable plasmid        MGE length: 161029 bp
Accession: NZ_CP091302        Location: 1..161029         Organism: Enterococcus faecium strain UK043       Replicon: plasmid pUK043_1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L3K57_RS13945 (L3K57_13945) 77..1625 - 1549 Protein_0 IS66 family transposase ISCde1 Transposase
L3K57_RS13950 (L3K57_13950) 1727..2080 - 354 WP_002287659.1 IS66 family transposase ISDeal1 Transposase
L3K57_RS13955 (L3K57_13955) 2070..2264 - 195 WP_002285758.1 hypothetical protein -
L3K57_RS13960 (L3K57_13960) 2490..3692 - 1203 WP_010729379.1 site-specific integrase -
L3K57_RS13965 (L3K57_13965) 3695..3889 - 195 WP_002351139.1 DUF3173 domain-containing protein -
L3K57_RS13970 (L3K57_13970) 3936..4784 - 849 WP_010729378.1 rep protein -
L3K57_RS13975 (L3K57_13975) 4989..5339 - 351 WP_010729377.1 hypothetical protein -
L3K57_RS13980 (L3K57_13980) 5517..6380 + 864 WP_010729376.1 helix-turn-helix transcriptional regulator -
L3K57_RS13985 (L3K57_13985) 7004..7996 + 993 WP_005233042.1 ABC transporter permease subunit -
L3K57_RS13990 (L3K57_13990) 8012..8896 + 885 WP_005230433.1 carbohydrate ABC transporter permease -
L3K57_RS13995 (L3K57_13995) 8945..10552 + 1608 WP_010729375.1 ABC transporter substrate-binding protein -
L3K57_RS14000 (L3K57_14000) 10553..12037 + 1485 WP_010729374.1 glycoside hydrolase family 32 protein -
L3K57_RS14005 (L3K57_14005) 12214..13206 + 993 WP_010729373.1 LacI family DNA-binding transcriptional regulator -
L3K57_RS14010 (L3K57_14010) 13258..14127 + 870 WP_010729372.1 ROK family protein -
L3K57_RS14015 (L3K57_14015) 14547..16160 - 1614 WP_002288610.1 glutamine-hydrolyzing GMP synthase -
L3K57_RS14020 (L3K57_14020) 16167..17441 - 1275 WP_010729371.1 ISL3 family transposase IS1476 Transposase
L3K57_RS14025 (L3K57_14025) 17729..18382 + 654 WP_002285815.1 Regulator of RpoS VF
L3K57_RS14030 (L3K57_14030) 18379..19698 + 1320 WP_002300494.1 HAMP domain-containing sensor histidine kinase -
L3K57_RS14035 (L3K57_14035) 19800..20480 - 681 WP_002325565.1 IS6 family transposase IS1216E Transposase
L3K57_RS14040 (L3K57_14040) 20560..20835 + 276 WP_236918136.1 hypothetical protein -
L3K57_RS14045 (L3K57_14045) 20849..21538 + 690 WP_000718009.1 hypothetical protein -
L3K57_RS14050 (L3K57_14050) 21663..24014 + 2352 WP_000344083.1 DUF1906 domain-containing protein -
L3K57_RS14055 (L3K57_14055) 24103..24489 + 387 WP_000391061.1 hypothetical protein -
L3K57_RS14060 (L3K57_14060) 24814..25431 + 618 WP_001224538.1 Tn3 family transposase TnpR_TnAs2 Transposase
L3K57_RS14065 (L3K57_14065) 25472..25771 + 300 WP_000366408.1 BRCT domain-containing protein -
L3K57_RS14070 (L3K57_14070) 25805..25972 + 168 WP_000824191.1 hypothetical protein -
L3K57_RS14075 (L3K57_14075) 26017..26622 - 606 WP_002321606.1 Tn3 family transposase TnpR_ISPa40 Transposase
L3K57_RS15905 26747..26869 + 123 WP_010729369.1 hypothetical protein -
L3K57_RS14080 (L3K57_14080) 26882..27562 - 681 WP_002319817.1 IS6 family transposase IS1297 Transposase
L3K57_RS14085 (L3K57_14085) 27562..27735 - 174 WP_010729368.1 hypothetical protein -
L3K57_RS14090 (L3K57_14090) 28030..28581 - 552 WP_002303113.1 DUF334 domain-containing protein -
L3K57_RS14095 (L3K57_14095) 28676..29056 - 381 Protein_31 IS6 family transposase IS1216V Transposase
L3K57_RS14100 (L3K57_14100) 29126..29806 + 681 WP_002319817.1 IS6 family transposase IS1297 Transposase
L3K57_RS14105 (L3K57_14105) 30150..30404 + 255 Protein_33 replication initiation protein -
L3K57_RS14110 (L3K57_14110) 30474..30986 + 513 WP_002387940.1 IS3 family transposase ISPa31 Transposase
L3K57_RS14115 (L3K57_14115) 30983..32020 + 1038 WP_002303110.1 IS3 family transposase ISSde10 Transposase
L3K57_RS14120 (L3K57_14120) 32097..32777 - 681 WP_001015311.1 IS6 family transposase IS1216E Transposase
L3K57_RS14125 (L3K57_14125) 32852..33307 + 456 Protein_37 rRNA adenine N-6-methyltransferase family protein -
L3K57_RS14130 (L3K57_14130) 33570..34433 - 864 WP_001284311.1 zeta toxin family protein Toxin Detail
L3K57_RS14135 (L3K57_14135) 34435..34707 - 273 WP_000301765.1 antitoxin Antitoxin Detail
L3K57_RS14140 (L3K57_14140) 34724..34939 - 216 WP_001835296.1 peptide-binding protein -
L3K57_RS14145 (L3K57_14145) 35031..35288 - 258 Protein_41 chromosome partitioning protein ParA -
L3K57_RS14150 (L3K57_14150) 35344..36024 - 681 WP_001015311.1 IS6 family transposase IS1216E Transposase
L3K57_RS14155 (L3K57_14155) 36244..36420 + 177 Protein_43 IS6 family transposase -
L3K57_RS14160 (L3K57_14160) 36497..38045 - 1549 Protein_44 IS66 family transposase ISCde1 Transposase
L3K57_RS14165 (L3K57_14165) 38147..38500 - 354 WP_002287659.1 IS66 family transposase ISDeal1 Transposase
L3K57_RS14170 (L3K57_14170) 38490..38684 - 195 WP_002285758.1 hypothetical protein -
L3K57_RS14175 (L3K57_14175) 38767..39252 - 486 Protein_47 IS256 family transposase ISEfa13 Transposase
L3K57_RS14180 (L3K57_14180) 39490..40350 + 861 WP_002349114.1 Rossmann-like and DUF2520 domain-containing protein -
L3K57_RS14185 (L3K57_14185) 40362..41189 + 828 WP_002287874.1 3-methyl-2-oxobutanoate hydroxymethyltransferase -
L3K57_RS14190 (L3K57_14190) 41204..42052 + 849 WP_002287875.1 pantoate--beta-alanine ligase -
L3K57_RS14195 (L3K57_14195) 42062..42457 + 396 WP_002287876.1 aspartate 1-decarboxylase -
L3K57_RS14200 (L3K57_14200) 42659..43444 + 786 Protein_52 IS3 family transposase -
L3K57_RS14205 (L3K57_14205) 43437..43679 - 243 Protein_53 IS3 family transposase -
L3K57_RS14210 (L3K57_14210) 43977..45155 - 1179 WP_002346943.1 IS256 family transposase ISEf1 Transposase
L3K57_RS14215 (L3K57_14215) 45406..45666 + 261 WP_002313174.1 hypothetical protein -
L3K57_RS14220 (L3K57_14220) 45940..47232 + 1293 WP_002301811.1 IS256 family transposase ISBsu2 Transposase
L3K57_RS14225 (L3K57_14225) 47801..48963 + 1163 WP_086956687.1 IS3 family transposase IS1485 Transposase
L3K57_RS14230 (L3K57_14230) 49734..50468 + 735 WP_002301131.1 GntR family transcriptional regulator -
L3K57_RS14235 (L3K57_14235) 50484..51653 + 1170 WP_002301130.1 SIS domain-containing protein -
L3K57_RS14240 (L3K57_14240) 51669..52664 + 996 WP_002301128.1 tagatose-bisphosphate aldolase -
L3K57_RS14245 (L3K57_14245) 52743..53669 + 927 WP_002298736.1 PEP phosphonomutase -
L3K57_RS14250 (L3K57_14250) 53688..54938 + 1251 WP_002301126.1 PTS sugar transporter subunit IIC -
L3K57_RS14255 (L3K57_14255) 55069..56022 + 954 WP_000222572.1 IS30 family transposase IS1252 Transposase
L3K57_RS14260 (L3K57_14260) 56130..57215 - 1086 WP_002301591.1 tyrosine recombinase XerS -
L3K57_RS14265 (L3K57_14265) 59291..59809 - 519 WP_002287870.1 ClbS/DfsB family four-helix bundle protein -
L3K57_RS14270 (L3K57_14270) 60927..62089 + 1163 WP_086956687.1 IS3 family transposase IS1485 Transposase
L3K57_RS14275 (L3K57_14275) 62380..62490 + 111 Protein_67 transposase -
L3K57_RS14280 (L3K57_14280) 62587..63063 - 477 WP_002300328.1 PTS glucose transporter subunit IIA -
L3K57_RS14285 (L3K57_14285) 63076..64578 - 1503 WP_002289252.1 PTS transporter subunit EIIC -
L3K57_RS14290 (L3K57_14290) 64592..65281 - 690 WP_002289253.1 N-acetylmannosamine-6-phosphate 2-epimerase -
L3K57_RS14295 (L3K57_14295) 65442..66260 + 819 WP_002289254.1 MurR/RpiR family transcriptional regulator -
L3K57_RS14300 (L3K57_14300) 66490..66720 + 231 WP_002289255.1 resolvase -
L3K57_RS14305 (L3K57_14305) 66943..67041 - 99 Protein_73 IS30 family transposase -
L3K57_RS14310 (L3K57_14310) 67306..67761 - 456 WP_002301718.1 IS200-IS605 family transposase ISAac3 Transposase
L3K57_RS14315 (L3K57_14315) 68004..69430 + 1427 Protein_75 IS3 family transposase ISEfa10 Transposase
L3K57_RS14320 (L3K57_14320) 69600..70562 - 963 WP_002302077.1 LacI family DNA-binding transcriptional regulator -
L3K57_RS14325 (L3K57_14325) 70564..72003 - 1440 WP_002302078.1 sucrose-6-phosphate hydrolase -
L3K57_RS14330 (L3K57_14330) 72188..74134 + 1947 WP_002293868.1 sucrose-specific PTS transporter subunit IIBC -
L3K57_RS14335 (L3K57_14335) 74398..75270 + 873 WP_002292418.1 ROK family protein -
L3K57_RS14340 (L3K57_14340) 75605..76256 + 652 Protein_80 IS6 family transposase IS1216V Transposase
L3K57_RS14345 (L3K57_14345) 76286..76885 - 600 WP_002322465.1 AbiH family protein -
L3K57_RS14350 (L3K57_14350) 76949..77548 - 600 WP_002301839.1 Tyrosine recombinase XerD VF
L3K57_RS14355 (L3K57_14355) 78043..78261 - 219 Protein_83 IS256 family transposase ISLgar5 Transposase
L3K57_RS14360 (L3K57_14360) 78502..78684 + 183 WP_002300846.1 hypothetical protein -
L3K57_RS14365 (L3K57_14365) 78668..78853 + 186 WP_002305884.1 IS66 family transposase ISEbi1 Transposase
L3K57_RS14370 (L3K57_14370) 79096..80616 + 1521 WP_002300843.1 IS66 family transposase ISDeal1 Transposase
L3K57_RS14375 (L3K57_14375) 80803..81375 - 573 WP_002300842.1 hypothetical protein VF
L3K57_RS14380 (L3K57_14380) 81382..82044 - 663 WP_002300841.1 hypothetical protein VF
L3K57_RS14385 (L3K57_14385) 82060..82575 - 516 WP_002300840.1 YjbQ family protein -
L3K57_RS14390 (L3K57_14390) 82577..82861 - 285 WP_002300838.1 PTS sugar transporter subunit IIB -
L3K57_RS14395 (L3K57_14395) 82895..84223 - 1329 WP_002300836.1 PTS transporter subunit IIC -
L3K57_RS14400 (L3K57_14400) 84237..84692 - 456 WP_002300835.1 PTS sugar transporter subunit IIA -
L3K57_RS14405 (L3K57_14405) 84695..86641 - 1947 WP_002300833.1 PTS sugar transporter subunit IIA -
L3K57_RS14410 (L3K57_14410) 87030..88208 - 1179 WP_000997695.1 IS256 family transposase ISEf1 Transposase
L3K57_RS14415 (L3K57_14415) 88580..88843 - 264 WP_002300807.1 uberolysin/carnocyclin family circular bacteriocin -
L3K57_RS14420 (L3K57_14420) 88964..89917 + 954 WP_000222572.1 IS30 family transposase IS1252 Transposase
L3K57_RS14425 (L3K57_14425) 90886..91242 - 357 WP_002311569.1 hypothetical protein -
L3K57_RS14430 (L3K57_14430) 91301..91480 - 180 WP_002300804.1 hypothetical protein -
L3K57_RS14435 (L3K57_14435) 91925..92197 - 273 WP_002300801.1 hypothetical protein -
L3K57_RS14440 (L3K57_14440) 92207..92362 - 156 WP_002300799.1 hypothetical protein -
L3K57_RS14445 (L3K57_14445) 92378..92629 - 252 WP_002300797.1 hypothetical protein -
L3K57_RS14450 (L3K57_14450) 92629..92835 - 207 WP_002305810.1 hypothetical protein -
L3K57_RS14455 (L3K57_14455) 93278..93478 - 201 WP_224446650.1 hypothetical protein -
L3K57_RS14460 (L3K57_14460) 93670..93814 + 145 Protein_104 putative holin-like toxin -
L3K57_RS14465 (L3K57_14465) 93973..94230 - 258 WP_002295625.1 hypothetical protein -
L3K57_RS14470 (L3K57_14470) 94252..94737 - 486 Protein_106 single-stranded DNA-binding protein -
L3K57_RS14475 (L3K57_14475) 94740..95639 - 900 WP_002301800.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
L3K57_RS14480 (L3K57_14480) 95652..96248 - 597 WP_002299811.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
L3K57_RS14485 (L3K57_14485) 96329..96478 - 150 WP_002295632.1 hypothetical protein -
L3K57_RS14490 (L3K57_14490) 96494..98603 - 2110 Protein_110 DNA topoisomerase III -
L3K57_RS14495 (L3K57_14495) 98614..100083 - 1470 WP_002313123.1 toprim domain-containing protein -
L3K57_RS14500 (L3K57_14500) 100146..102517 - 2372 Protein_112 ArdC-like ssDNA-binding domain-containing protein -
L3K57_RS14505 (L3K57_14505) 102927..104102 + 1176 Protein_113 IS110 family transposase ISSpn10 Transposase
L3K57_RS14510 (L3K57_14510) 104191..105465 - 1275 WP_002398627.1 ISL3 family transposase IS1476 Transposase
L3K57_RS14515 (L3K57_14515) 105923..106264 - 342 WP_002295674.1 DUF5406 family protein -
L3K57_RS14520 (L3K57_14520) 106883..107215 - 333 WP_002323647.1 type IV conjugative transfer system protein TraE -
L3K57_RS14525 (L3K57_14525) 108038..109078 - 1041 WP_002326172.1 replication initiator protein A -
L3K57_RS14530 (L3K57_14530) 110244..110330 + 87 Protein_118 single-stranded DNA-binding protein -
L3K57_RS14535 (L3K57_14535) 110968..111108 + 141 WP_002290398.1 hypothetical protein -
L3K57_RS14540 (L3K57_14540) 111331..112479 - 1149 WP_002323589.1 IS200-IS605 family transposase ISEfa4 Transposase
L3K57_RS14545 (L3K57_14545) 112496..112900 - 405 WP_002287522.1 IS200-IS605 family transposase ISEfa4 Transposase
L3K57_RS14550 (L3K57_14550) 113259..113513 + 255 WP_002323399.1 hypothetical protein -
L3K57_RS14555 (L3K57_14555) 113514..113831 + 318 WP_002290394.1 type II toxin-antitoxin system RelE/ParE family toxin -
L3K57_RS14560 (L3K57_14560) 114390..115325 + 936 WP_002323400.1 hypothetical protein -
L3K57_RS14565 (L3K57_14565) 115419..116327 + 909 Protein_125 IS982 family transposase ISEfm1 Transposase
L3K57_RS14570 (L3K57_14570) 116409..117263 + 855 WP_002338109.1 AraC family transcriptional regulator -
L3K57_RS14575 (L3K57_14575) 117360..119609 + 2250 WP_002314387.1 alpha-galactosidase -
L3K57_RS14580 (L3K57_14580) 119612..120787 + 1176 WP_002336205.1 MFS transporter -
L3K57_RS14585 (L3K57_14585) 120790..121698 - 909 Protein_129 IS982 family transposase ISEfm1 Transposase
L3K57_RS14590 (L3K57_14590) 121932..122195 + 264 WP_236918134.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin Detail
L3K57_RS14595 (L3K57_14595) 122195..122467 + 273 WP_002314366.1 Txe/YoeB family addiction module toxin Toxin Detail
L3K57_RS14600 (L3K57_14600) 122544..122873 + 330 WP_002292678.1 AbrB family transcriptional regulator -
L3K57_RS14605 (L3K57_14605) 122863..123149 + 287 Protein_133 type II toxin-antitoxin system RelE/ParE family toxin -
L3K57_RS14610 (L3K57_14610) 123434..124291 + 858 WP_002292680.1 ParA family protein -
L3K57_RS14615 (L3K57_14615) 124292..124840 + 549 WP_002292681.1 hypothetical protein -
L3K57_RS14620 (L3K57_14620) 125100..125477 + 378 WP_010729388.1 hypothetical protein -
L3K57_RS14625 (L3K57_14625) 125511..126191 - 681 WP_002331383.1 IS6 family transposase IS1216E Transposase
L3K57_RS14630 (L3K57_14630) 126267..126910 - 644 Protein_138 transposase -
L3K57_RS14635 (L3K57_14635) 127185..127727 + 543 WP_002298088.1 hypothetical protein -
L3K57_RS14640 (L3K57_14640) 127883..128332 + 450 WP_010729386.1 TlpA disulfide reductase family protein -
L3K57_RS14650 (L3K57_14650) 129600..129755 + 156 Protein_142 4Fe-4S binding protein -
L3K57_RS14655 (L3K57_14655) 129774..131051 + 1278 WP_002301194.1 ABC transporter permease -
L3K57_RS14660 (L3K57_14660) 131061..131717 + 657 WP_002298083.1 putative ABC transporter ATP-binding protein VF
L3K57_RS14665 (L3K57_14665) 131717..133093 + 1377 WP_002298085.1 ABC transporter permease -
L3K57_RS14670 (L3K57_14670) 133223..134422 + 1200 WP_010729384.1 IS256 family transposase ISBsu2 Transposase
L3K57_RS14675 (L3K57_14675) 134394..135890 + 1497 WP_080440524.1 IS1182 family transposase ISEfa7 Transposase
L3K57_RS14680 (L3K57_14680) 136373..136516 + 144 WP_141759899.1 glycerophosphodiester phosphodiesterase -
L3K57_RS14685 (L3K57_14685) 136562..137095 + 534 WP_002389935.1 hypothetical protein -
L3K57_RS14690 (L3K57_14690) 137239..138528 + 1290 WP_002299928.1 ABC transporter substrate-binding protein -
L3K57_RS14695 (L3K57_14695) 138613..139485 + 873 WP_002299927.1 sugar ABC transporter permease -
L3K57_RS14700 (L3K57_14700) 139475..140290 + 816 WP_002299926.1 carbohydrate ABC transporter permease -
L3K57_RS14705 (L3K57_14705) 140306..141430 + 1125 WP_002299925.1 Maltose/maltodextrin import ATP-binding protein MalK VF
L3K57_RS14710 (L3K57_14710) 141408..142211 + 804 WP_002299923.1 metallophosphoesterase -
L3K57_RS14715 (L3K57_14715) 142671..142934 + 264 WP_002389939.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
L3K57_RS14720 (L3K57_14720) 142918..143253 + 336 WP_014748798.1 type II toxin-antitoxin system PemK/MazF family toxin -
L3K57_RS14725 (L3K57_14725) 143432..144646 - 1215 Protein_157 ISL3 family transposase ISEfa11 Transposase
L3K57_RS14730 (L3K57_14730) 144847..146121 + 1275 WP_002347634.1 ISL3 family transposase IS1476 Transposase
L3K57_RS14735 (L3K57_14735) 146504..147232 - 729 WP_002302980.1 helix-turn-helix domain-containing protein -
L3K57_RS14740 (L3K57_14740) 147210..148784 - 1575 WP_002340467.1 histidine kinase -
L3K57_RS14745 (L3K57_14745) 149013..149951 + 939 WP_002304874.1 sugar ABC transporter permease -
L3K57_RS14750 (L3K57_14750) 149963..150874 + 912 WP_002289655.1 carbohydrate ABC transporter permease -
L3K57_RS14755 (L3K57_14755) 150898..152370 + 1473 WP_010729380.1 extracellular solute-binding protein -
L3K57_RS14760 (L3K57_14760) 152421..153032 + 612 WP_002304878.1 DUF624 domain-containing protein -
L3K57_RS14765 (L3K57_14765) 153062..154975 + 1914 WP_002304880.1 beta-N-acetylhexosaminidase -
L3K57_RS14770 (L3K57_14770) 155103..158084 + 2982 WP_002305865.1 glycoside hydrolase family 2 TIM barrel-domain containing protein -
L3K57_RS14775 (L3K57_14775) 158416..159801 + 1386 WP_236918135.1 O-GlcNAcase NagJ VF
L3K57_RS14780 (L3K57_14780) 159782..160714 + 933 WP_002288609.1 hypothetical protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance