MGE detailed information
MGE type: Conjugative plasmid MGE length: 129210 bp
Accession: NZ_CP089135 Location: 1..129210 Organism: Escherichia coli strain XD35 Replicon: plasmid pXD35002
Accession: NZ_CP089135 Location: 1..129210 Organism: Escherichia coli strain XD35 Replicon: plasmid pXD35002
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K0768_RS01300 (1) | 1..1011 | + | 1011 | WP_053263823.1 | RepB family plasmid replication initiator protein | - |
| K0768_RS01305 (1728) | 1728..2468 | - | 741 | WP_001515717.1 | tyrosine-type recombinase/integrase | - |
| K0768_RS01310 (2871) | 2871..3560 | - | 690 | Protein_2 | IS3 family transposase ISEhe3 | Transposase |
| K0768_RS01315 (3595) | 3595..3792 | - | 198 | Protein_3 | IS66 family transposase | - |
| K0768_RS01325 (3855) | 3855..4559 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K0768_RS01330 (4613) | 4613..5080 | + | 468 | Protein_5 | conjugal transfer protein | - |
| K0768_RS01335 (5325) | 5325..5441 | + | 117 | WP_001814923.1 | tetracycline resistance determinant leader peptide | - |
| K0768_RS01340 (5457) | 5457..7376 | + | 1920 | WP_025989258.1 | Tetracycline resistance protein TetM from transposon TnFO1 | VF |
| K0768_RS01345 (7495) | 7495..7662 | + | 168 | WP_000336323.1 | cysteine-rich KTR domain-containing protein | - |
| K0768_RS01350 (7923) | 7923..8555 | + | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| K0768_RS01355 (8802) | 8802..9134 | - | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| K0768_RS01360 (9257) | 9257..10095 | - | 839 | Protein_11 | Streptomycin 3''-adenylyltransferase | ARG |
| K0768_RS01365 (10188) | 10188..11447 | - | 1260 | WP_000095725.1 | Bicyclomycin resistance protein | ARG |
| K0768_RS01370 (11662) | 11662..12500 | - | 839 | Protein_13 | Streptomycin 3''-adenylyltransferase | ARG |
| K0768_RS01375 (12506) | 12506..12796 | - | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| K0768_RS01380 (12908) | 12908..13405 | - | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| K0768_RS01385 (13550) | 13550..14563 | + | 1014 | WP_000845039.1 | IS91 family transposase ISAzo26 | Transposase |
| K0768_RS01390 (14766) | 14766..15116 | + | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| K0768_RS01395 (15292) | 15292..15852 | + | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| K0768_RS01400 (15856) | 15856..18822 | + | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| K0768_RS01405 (18880) | 18880..19122 | + | 243 | WP_000844627.1 | transposase | - |
| K0768_RS01410 (19154) | 19154..19804 | - | 651 | WP_219534852.1 | tetracycline resistance transcriptional repressor TetR | - |
| K0768_RS01415 (19910) | 19910..21109 | + | 1200 | WP_001493765.1 | Tetracycline resistance protein, class C | ARG |
| K0768_RS01420 (21141) | 21141..22025 | - | 885 | WP_000058717.1 | EamA family transporter | - |
| K0768_RS01425 (22163) | 22163..22555 | - | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| K0768_RS01430 (22559) | 22559..24310 | + | 1752 | Protein_25 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| K0768_RS01435 (24543) | 24543..24950 | - | 408 | WP_034167712.1 | hypothetical protein | - |
| K0768_RS01440 (25015) | 25015..25209 | + | 195 | WP_161759552.1 | DUF2384 domain-containing protein | - |
| K0768_RS01445 (25408) | 25408..25623 | - | 216 | WP_034167711.1 | hypothetical protein | - |
| K0768_RS01450 (26058) | 26058..26267 | + | 210 | Protein_29 | hypothetical protein | - |
| K0768_RS01455 (26392) | 26392..27270 | - | 879 | Protein_30 | IS5 family transposase ISKpn26 | Transposase |
| K0768_RS01460 (27324) | 27324..28028 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K0768_RS01465 (28142) | 28142..28918 | + | 777 | WP_001199192.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| K0768_RS01470 (29147) | 29147..30172 | + | 1026 | WP_000742814.1 | Hygromycin-B 4-O-kinase | ARG |
| K0768_RS01475 (30247) | 30247..30534 | + | 288 | Protein_34 | AAC(3) family N-acetyltransferase | - |
| K0768_RS01480 (30594) | 30594..31346 | - | 753 | WP_000602738.1 | IS6 family transposase ISRle7 | Transposase |
| K0768_RS01485 (31408) | 31408..32931 | + | 1524 | Protein_36 | Tn3 family transposase TnpA_ISRsp12 | Transposase |
| K0768_RS01490 (32964) | 32964..34205 | - | 1242 | Protein_37 | IS91 family transposase ISVsa3 | Transposase |
| K0768_RS01495 (34277) | 34277..35050 | - | 774 | WP_001053381.1 | IS21 family transposase ISEc57 | Transposase |
| K0768_RS01500 (35050) | 35050..36075 | - | 1026 | WP_021545039.1 | IS21 family transposase ISEc57 | Transposase |
| K0768_RS01505 (36164) | 36164..36325 | - | 162 | Protein_40 | IS91 family transposase | - |
| K0768_RS01510 (36437) | 36437..36742 | - | 306 | WP_001255015.1 | HTH-type transcriptional regulator CynR | VF |
| K0768_RS01515 (36770) | 36770..37984 | - | 1215 | WP_058100717.1 | Bicyclomycin resistance protein | ARG |
| K0768_RS01520 (38201) | 38201..39085 | - | 885 | WP_001447541.1 | DUF3363 domain-containing protein | - |
| K0768_RS01525 (39116) | 39116..39892 | - | 777 | Protein_44 | IS91 family transposase ISVsa3 | Transposase |
| K0768_RS01530 (39943) | 39943..40647 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| K0768_RS01535 (40657) | 40657..41415 | + | 759 | WP_161997274.1 | IS6 family transposase IS6100 | Transposase |
| K0768_RS01540 (41908) | 41908..42492 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| K0768_RS01545 (42492) | 42492..43730 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| K0768_RS01550 (43727) | 43727..44632 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| K0768_RS01555 (44754) | 44754..45458 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K0768_RS01560 (45593) | 45593..45688 | + | 96 | WP_013362819.1 | 23S rRNA methyltransferase attenuation leader peptide | - |
| K0768_RS01565 (45814) | 45814..46551 | + | 738 | WP_013362818.1 | rRNA adenine N-6-methyltransferase | ARG |
| K0768_RS01570 (47181) | 47181..47630 | + | 450 | WP_013362817.1 | hypothetical protein | - |
| K0768_RS01575 (47591) | 47591..47932 | + | 342 | WP_023909256.1 | 60 kDa chaperonin 2 | VF |
| K0768_RS01580 (48207) | 48207..49691 | + | 1485 | WP_032152108.1 | IS91 family transposase ISVsa3 | Transposase |
| K0768_RS01585 (50014) | 50014..50718 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K0768_RS01590 (50828) | 50828..50890 | - | 63 | Protein_57 | hypothetical protein | - |
| K0768_RS01595 (51187) | 51187..52158 | - | 972 | WP_032482493.1 | IS91 family transposase ISAzo26 | Transposase |
| K0768_RS01600 (52561) | 52561..53193 | - | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| K0768_RS01605 (53216) | 53216..53491 | + | 276 | WP_109023896.1 | hypothetical protein | - |
| K0768_RS01610 (53494) | 53494..54285 | - | 792 | WP_000034420.1 | Dihydropteroate synthase | ARG |
| K0768_RS01615 (54754) | 54754..54999 | - | 246 | WP_001354008.1 | GrpB family protein | - |
| K0768_RS01620 (55037) | 55037..55900 | - | 864 | WP_000612791.1 | SDR family oxidoreductase | - |
| K0768_RS01625 (56046) | 56046..56303 | - | 258 | Protein_64 | hypothetical protein | - |
| K0768_RS01630 (56358) | 56358..57062 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K0768_RS01635 (57128) | 57128..57349 | + | 222 | Protein_66 | tyrosine-type recombinase/integrase | - |
| K0768_RS01640 (57554) | 57554..58467 | + | 914 | Protein_67 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| K0768_RS01645 (58614) | 58614..58823 | - | 210 | Protein_68 | class A beta-lactamase | - |
| K0768_RS01650 (58887) | 58887..59591 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K0768_RS01655 (59657) | 59657..60202 | + | 546 | Protein_70 | Tn3 family transposase TnpA_Tn3 | Transposase |
| K0768_RS01660 (60238) | 60238..60653 | - | 416 | Protein_71 | IS1 family transposase IS1R | Transposase |
| K0768_RS01665 (60902) | 60902..61303 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| K0768_RS01670 (61236) | 61236..61493 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| K0768_RS01675 (61586) | 61586..62239 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| K0768_RS01680 (63177) | 63177..64034 | - | 858 | WP_039002220.1 | incFII family plasmid replication initiator RepA | - |
| K0768_RS01685 (64027) | 64027..64101 | - | 75 | WP_061357229.1 | RepA leader peptide Tap | - |
| K0768_RS01690 (64333) | 64333..64590 | - | 258 | WP_001541895.1 | replication regulatory protein RepA | - |
| K0768_RS01695 (64858) | 64858..65007 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (65051) | 65051..65112 | + | 62 | NuclAT_0 | - | Antitoxin Detail |
| - (65051) | 65051..65112 | + | 62 | NuclAT_0 | - | Antitoxin Detail |
| - (65051) | 65051..65112 | + | 62 | NuclAT_0 | - | Antitoxin Detail |
| - (65051) | 65051..65112 | + | 62 | NuclAT_0 | - | Antitoxin Detail |
| K0768_RS01700 (65454) | 65454..65666 | - | 213 | WP_001541896.1 | ANR family transcriptional regulator | - |
| K0768_RS01705 (65801) | 65801..66361 | - | 561 | WP_000139310.1 | fertility inhibition protein FinO | - |
| K0768_RS01710 (66416) | 66416..67159 | - | 744 | WP_039002216.1 | conjugal transfer pilus acetylase TraX | - |
| K0768_RS01715 (67179) | 67179..72449 | - | 5271 | WP_054377139.1 | Multifunctional conjugation protein TraI | Relaxase |
| K0768_RS01720 (72449) | 72449..74629 | - | 2181 | WP_063078088.1 | type IV conjugative transfer system coupling protein TraD | - |
| K0768_RS01725 (74882) | 74882..75613 | - | 732 | WP_000850424.1 | conjugal transfer complement resistance protein TraT | - |
| K0768_RS01730 (75645) | 75645..76148 | - | 504 | WP_201273844.1 | surface exclusion protein | - |
| K0768_RS01735 (76163) | 76163..78985 | - | 2823 | WP_001007048.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| K0768_RS01740 (78982) | 78982..80355 | - | 1374 | WP_170926237.1 | conjugal transfer pilus assembly protein TraH | - |
| K0768_RS01745 (80355) | 80355..80717 | - | 363 | WP_001443292.1 | P-type conjugative transfer protein TrbJ | - |
| K0768_RS01750 (80647) | 80647..81192 | - | 546 | WP_000052613.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| K0768_RS01755 (81179) | 81179..81415 | - | 237 | WP_054377141.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| K0768_RS01760 (81576) | 81576..82319 | - | 744 | WP_039002205.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| K0768_RS01765 (82312) | 82312..82572 | - | 261 | WP_000864348.1 | conjugal transfer protein TrbE | - |
| K0768_RS01770 (82599) | 82599..84407 | - | 1809 | WP_115739629.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| K0768_RS01775 (84404) | 84404..85042 | - | 639 | WP_000777691.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| K0768_RS01780 (85051) | 85051..86043 | - | 993 | WP_023148235.1 | conjugal transfer pilus assembly protein TraU | - |
| K0768_RS01785 (86040) | 86040..86672 | - | 633 | WP_001749440.1 | type-F conjugative transfer system protein TraW | - |
| K0768_RS01790 (86669) | 86669..87055 | - | 387 | WP_039002198.1 | type-F conjugative transfer system protein TrbI | - |
| K0768_RS01795 (87052) | 87052..89679 | - | 2628 | WP_001064265.1 | type IV secretion system protein TraC | - |
| K0768_RS01800 (89839) | 89839..90060 | - | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| K0768_RS01805 (90195) | 90195..90710 | - | 516 | WP_000724019.1 | type IV conjugative transfer system lipoprotein TraV | - |
| K0768_RS01810 (90707) | 90707..91027 | - | 321 | WP_001057285.1 | conjugal transfer protein TrbD | - |
| K0768_RS01815 (91014) | 91014..91601 | - | 588 | WP_000002772.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| K0768_RS01820 (91591) | 91591..93018 | - | 1428 | WP_219534858.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| K0768_RS01825 (93018) | 93018..93746 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| K0768_RS01830 (93733) | 93733..94299 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| K0768_RS01835 (94321) | 94321..94632 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| K0768_RS01840 (94637) | 94637..94999 | - | 363 | WP_000994784.1 | type IV conjugative transfer system pilin TraA | - |
| K0768_RS01845 (95032) | 95032..95433 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| K0768_RS01850 (95526) | 95526..96215 | - | 690 | WP_039002187.1 | conjugal transfer transcriptional regulator TraJ | - |
| K0768_RS01855 (96402) | 96402..96785 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| K0768_RS01860 (97106) | 97106..97708 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| K0768_RS01865 (98005) | 98005..98826 | - | 822 | WP_153449150.1 | DUF932 domain-containing protein | - |
| K0768_RS01870 (98948) | 98948..99235 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| K0768_RS01875 (99260) | 99260..99466 | - | 207 | WP_000547968.1 | hypothetical protein | - |
| K0768_RS01880 (99536) | 99536..99709 | + | 174 | Protein_115 | hypothetical protein | - |
| K0768_RS01885 (100438) | 100438..102105 | + | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
| K0768_RS01890 (102419) | 102419..102610 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| K0768_RS01895 (102607) | 102607..103029 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| K0768_RS01900 (103076) | 103076..103501 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| K0768_RS01905 (103918) | 103918..104694 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| K0768_RS01910 (104745) | 104745..105263 | - | 519 | WP_123325260.1 | DUF1380 family protein | - |
| K0768_RS01915 (105193) | 105193..105414 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| K0768_RS01920 (105415) | 105415..106098 | - | 684 | WP_000086185.1 | DNA methylase | - |
| K0768_RS01925 (106175) | 106175..106486 | - | 312 | WP_011254640.1 | hypothetical protein | - |
| K0768_RS01930 (106483) | 106483..107385 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| K0768_RS01935 (108252) | 108252..109223 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| K0768_RS01940 (109223) | 109223..110389 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| K0768_RS01945 (110977) | 110977..111732 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| K0768_RS01950 (112506) | 112506..113312 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| K0768_RS01955 (113313) | 113313..113618 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| K0768_RS01960 (113620) | 113620..113838 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| K0768_RS01965 (114428) | 114428..114658 | + | 231 | WP_001261282.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| K0768_RS01970 (114655) | 114655..115071 | + | 417 | WP_016236302.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| K0768_RS01975 (115145) | 115145..116707 | + | 1563 | WP_004206609.1 | AAA family ATPase | - |
| K0768_RS01980 (116692) | 116692..117714 | + | 1023 | WP_000361404.1 | helicase UvrD | - |
| K0768_RS01985 (117895) | 117895..118125 | - | 231 | Protein_136 | IS1 family transposase IS1N | Transposase |
| K0768_RS01990 (118180) | 118180..118884 | - | 705 | WP_009364894.1 | IS6 family transposase IS26 | Transposase |
| K0768_RS01995 (119083) | 119083..119466 | + | 384 | WP_001514447.1 | IS66 family transposase IS682 | Transposase |
| K0768_RS02000 (119463) | 119463..119810 | + | 348 | WP_000609174.1 | IS66 family transposase ISCfr14 | Transposase |
| K0768_RS02005 (119860) | 119860..121395 | + | 1536 | WP_023154011.1 | IS66 family transposase ISSgsp1 | Transposase |
| K0768_RS02010 (121813) | 121813..122142 | + | 330 | WP_000493286.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| K0768_RS02015 (122123) | 122123..122404 | + | 282 | WP_000780222.1 | helix-turn-helix transcriptional regulator | - |
| K0768_RS02020 (122682) | 122682..123251 | + | 570 | Protein_143 | IS5 family transposase IS5D | Transposase |
| K0768_RS02025 (123306) | 123306..124010 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K0768_RS02030 (124123) | 124123..125103 | + | 981 | WP_016236480.1 | IS5 family transposase ISKpn26 | Transposase |
| K0768_RS02035 (126322) | 126322..127293 | - | 972 | WP_000817039.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| K0768_RS02040 (127293) | 127293..128459 | - | 1167 | WP_000523813.1 | Sporulation initiation inhibitor protein Soj | VF |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|