MGE detailed information
MGE type: Conjugative plasmid MGE length: 151915 bp
Accession: NZ_CP087571 Location: 1..151915 Organism: Escherichia coli strain 114 Replicon: plasmid p1OXA77
Accession: NZ_CP087571 Location: 1..151915 Organism: Escherichia coli strain 114 Replicon: plasmid p1OXA77
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LOS76_RS23000 () | 505..978 | - | 474 | WP_001389366.1 | Dihydrofolate reductase type 1 | ARG |
| LOS76_RS23005 () | 1136..2147 | + | 1012 | Protein_3 | IS91 family transposase ISWz1 | Transposase |
| LOS76_RS23010 () | 2350..2658 | + | 309 | Protein_4 | EAL domain-containing protein | - |
| LOS76_RS23015 () | 2549..3253 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| LOS76_RS23020 () | 3393..4157 | + | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| LOS76_RS23025 () | 4650..5234 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| LOS76_RS23030 () | 5234..6472 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| LOS76_RS23035 () | 6469..7374 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| LOS76_RS23040 () | 7496..8200 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| LOS76_RS23045 () | 8237..9364 | - | 1128 | WP_014837927.1 | DUF3883 domain-containing protein | - |
| LOS76_RS23050 () | 9415..9642 | - | 228 | WP_000248278.1 | hypothetical protein | - |
| LOS76_RS23055 () | 9666..9857 | + | 192 | WP_000951934.1 | hypothetical protein | - |
| LOS76_RS23060 () | 10339..10881 | - | 543 | WP_000587837.1 | AAA family ATPase | - |
| LOS76_RS23065 () | 10894..11754 | - | 861 | WP_000557454.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| LOS76_RS23070 () | 11897..12859 | + | 963 | Protein_16 | IS4 family transposase IS10R | Transposase |
| LOS76_RS23075 () | 12969..13814 | + | 846 | Protein_17 | IS4 family transposase IS10R | Transposase |
| LOS76_RS23080 () | 13869..14573 | - | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| LOS76_RS23085 () | 14535..16782 | + | 2248 | Protein_19 | Tn3 family transposase TnpA_Tn3 | Transposase |
| LOS76_RS23090 () | 16859..17563 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| LOS76_RS23095 () | 17617..18057 | - | 441 | Protein_21 | CatB-related O-acetyltransferase | - |
| LOS76_RS23100 () | 18195..19025 | - | 831 | WP_001334766.1 | Beta-lactamase OXA-1 | ARG |
| LOS76_RS23105 () | 19156..19710 | - | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| LOS76_RS23110 () | 19854..20555 | - | 702 | WP_231364123.1 | IS6-like element IS26 family transposase | - |
| LOS76_RS23115 () | 20627..22963 | + | 2337 | Protein_25 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| LOS76_RS23120 () | 23100..23501 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| LOS76_RS23125 () | 23434..23691 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| LOS76_RS23130 () | 23752..23970 | - | 219 | WP_231364127.1 | hypothetical protein | - |
| LOS76_RS23135 () | 23955..24308 | - | 354 | WP_231364129.1 | histidine phosphatase family protein | - |
| LOS76_RS23140 () | 24281..24433 | - | 153 | WP_001427870.1 | hypothetical protein | - |
| LOS76_RS23145 () | 25373..26230 | - | 858 | WP_000130640.1 | incFII family plasmid replication initiator RepA | - |
| LOS76_RS23150 () | 26223..26297 | - | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| LOS76_RS23160 () | 26659..28198 | + | 1540 | Protein_33 | IS21 family transposase ISEc12 | Transposase |
| LOS76_RS23165 () | 28213..28959 | + | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| LOS76_RS23170 () | 29119..29373 | - | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| LOS76_RS23175 () | 29670..29804 | - | 135 | WP_023144756.1 | Hok/Gef family protein | Toxin Detail |
| - () | 29849..29909 | + | 61 | NuclAT_1 | - | Antitoxin Detail |
| - () | 29849..29909 | + | 61 | NuclAT_1 | - | Antitoxin Detail |
| - () | 29849..29909 | + | 61 | NuclAT_1 | - | Antitoxin Detail |
| - () | 29849..29909 | + | 61 | NuclAT_1 | - | Antitoxin Detail |
| LOS76_RS23180 () | 29876..30162 | - | 287 | Protein_37 | DUF2726 domain-containing protein | - |
| LOS76_RS23185 () | 30675..30887 | - | 213 | WP_013023861.1 | hypothetical protein | - |
| LOS76_RS23190 () | 31018..31578 | - | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| LOS76_RS23195 () | 31633..32379 | - | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| LOS76_RS23200 () | 32399..34792 | - | 2394 | Protein_41 | Multifunctional conjugation protein TraI | Relaxase |
| LOS76_RS23205 () | 34762..35934 | - | 1173 | WP_231364135.1 | DUF3560 domain-containing protein | - |
| LOS76_RS23210 () | 35985..36503 | - | 519 | WP_123325260.1 | DUF1380 family protein | - |
| LOS76_RS23215 () | 36433..36654 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| LOS76_RS23220 () | 36655..37338 | - | 684 | WP_000086185.1 | DNA methylase | - |
| LOS76_RS23225 () | 37415..37726 | - | 312 | WP_011254640.1 | hypothetical protein | - |
| LOS76_RS23230 () | 37723..38625 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| LOS76_RS23235 () | 39492..40463 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| LOS76_RS23240 () | 40463..41629 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| LOS76_RS23245 () | 42217..42972 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| LOS76_RS23250 () | 43746..44552 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| LOS76_RS23255 () | 44553..44858 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| LOS76_RS23260 () | 44860..45078 | - | 219 | WP_023909027.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| LOS76_RS23265 () | 45712..45909 | + | 198 | WP_000215657.1 | hypothetical protein | - |
| LOS76_RS23270 () | 45906..46190 | - | 285 | WP_000642771.1 | hypothetical protein | - |
| LOS76_RS23275 () | 46210..47343 | - | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| LOS76_RS23280 () | 47606..50725 | - | 3120 | WP_023909028.1 | hypothetical protein | - |
| LOS76_RS23285 () | 51032..51262 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| LOS76_RS23290 () | 51259..51675 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| LOS76_RS23295 () | 51837..53975 | - | 2139 | WP_000350635.1 | AAA family ATPase | - |
| LOS76_RS23300 () | 54440..55435 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| LOS76_RS23305 () | 55478..56371 | + | 894 | WP_001553853.1 | S-4TM family putative pore-forming effector | - |
| LOS76_RS23315 () | 57419..60535 | - | 3117 | WP_031311986.1 | HsdR family type I site-specific deoxyribonuclease | - |
| LOS76_RS23320 () | 60657..61940 | - | 1284 | WP_001617890.1 | restriction endonuclease subunit S | - |
| LOS76_RS23325 () | 61937..63493 | - | 1557 | WP_001553856.1 | type I restriction-modification system subunit M | - |
| LOS76_RS23330 () | 63676..63897 | + | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| LOS76_RS23335 () | 63897..64277 | + | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| LOS76_RS23340 () | 64282..64461 | + | 180 | WP_001513661.1 | hypothetical protein | - |
| LOS76_RS23345 () | 64489..64767 | + | 279 | Protein_70 | pdcB | - |
| LOS76_RS23350 () | 64772..65185 | + | 414 | Protein_71 | IS3 family transposase ISLad1 | Transposase |
| LOS76_RS23355 () | 65981..66958 | + | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| LOS76_RS23360 () | 67243..67983 | - | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| LOS76_RS23365 () | 68104..68286 | - | 183 | WP_042065278.1 | hypothetical protein | - |
| LOS76_RS23370 () | 68353..68642 | - | 290 | Protein_75 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| LOS76_RS23375 () | 68629..68897 | - | 269 | Protein_76 | type II toxin-antitoxin system ParD family antitoxin | - |
| LOS76_RS23380 () | 69429..70598 | + | 1170 | WP_001072355.1 | hypothetical protein | - |
| LOS76_RS23385 () | 70631..70759 | + | 129 | Protein_78 | IS481 family transposase | - |
| LOS76_RS23390 () | 70794..70982 | - | 189 | Protein_79 | hypothetical protein | - |
| LOS76_RS23395 () | 71030..71727 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| LOS76_RS23400 () | 71743..71862 | + | 120 | Protein_81 | transcriptional regulator | - |
| LOS76_RS23405 () | 71840..72463 | - | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| LOS76_RS23410 () | 72545..73750 | + | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| LOS76_RS23415 () | 73863..74456 | - | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| LOS76_RS23420 () | 74590..75291 | + | 702 | WP_231364136.1 | IS6-like element IS26 family transposase | - |
| LOS76_RS23425 () | 75345..75710 | - | 366 | Protein_86 | chromate transporter | - |
| LOS76_RS23430 () | 75866..76069 | - | 204 | WP_000376616.1 | hypothetical protein | - |
| LOS76_RS23435 () | 76197..77036 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| LOS76_RS23440 () | 77030..77377 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| LOS76_RS23445 () | 77840..78100 | + | 261 | WP_000078108.1 | replication regulatory protein RepA | - |
| LOS76_RS24290 () | 78334..78408 | + | 75 | WP_001375168.1 | RepA leader peptide Tap | - |
| LOS76_RS23460 () | 78401..79258 | + | 858 | WP_000130959.1 | incFII family plasmid replication initiator RepA | - |
| LOS76_RS23465 () | 80197..80850 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| LOS76_RS23470 () | 80943..81200 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| LOS76_RS23475 () | 81133..81534 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| LOS76_RS23480 () | 81783..82198 | + | 416 | Protein_96 | IS1-like element IS1B family transposase | - |
| LOS76_RS23485 () | 82234..82779 | - | 546 | Protein_97 | Tn3 family transposase TnpA_Tn3 | Transposase |
| LOS76_RS23490 () | 82845..83546 | - | 702 | WP_231364123.1 | IS6 family transposase IS26 | Transposase |
| LOS76_RS23495 () | 83611..84291 | - | 681 | Protein_99 | IS91 family transposase ISAzo26 | Transposase |
| LOS76_RS23500 () | 84563..85263 | + | 701 | Protein_100 | IS6-like element IS26 family transposase | - |
| LOS76_RS23505 () | 85318..85743 | + | 426 | Protein_101 | TetR/AcrR family transcriptional regulator | - |
| LOS76_RS23510 () | 85763..86551 | + | 789 | WP_014839978.1 | winged helix-turn-helix domain-containing protein | - |
| LOS76_RS23515 () | 86551..87069 | + | 519 | WP_014839979.1 | FidL-like protein | - |
| LOS76_RS23520 () | 87074..87490 | - | 417 | WP_014839980.1 | Glutathione transferase FosA | ARG |
| LOS76_RS23525 () | 87876..88580 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| LOS76_RS23530 () | 88630..89373 | + | 744 | Protein_106 | Beta-lactamase TEM | ARG |
| LOS76_RS23535 () | 89632..90108 | + | 477 | WP_013023839.1 | WbuC family cupin fold metalloprotein | - |
| LOS76_RS23540 () | 90155..91030 | - | 876 | WP_015387340.1 | Beta-lactamase CTX-M-1 | ARG |
| LOS76_RS23545 () | 91452..92156 | - | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| LOS76_RS23550 () | 93736..93970 | + | 235 | Protein_110 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| LOS76_RS23555 () | 94098..94301 | + | 204 | Protein_111 | hypothetical protein | - |
| LOS76_RS23560 () | 94502..94852 | - | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| LOS76_RS23565 () | 94855..95817 | - | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| LOS76_RS23570 () | 95965..96258 | + | 294 | WP_231364137.1 | hypothetical protein | - |
| LOS76_RS23575 () | 96335..97018 | + | 684 | WP_000085883.1 | DNA methylase | - |
| LOS76_RS23580 () | 97019..97240 | + | 222 | WP_001104881.1 | hypothetical protein | - |
| LOS76_RS23585 () | 97254..97688 | + | 435 | WP_000274503.1 | DUF1380 family protein | - |
| LOS76_RS23590 () | 97739..98515 | + | 777 | WP_001383963.1 | hypothetical protein | - |
| LOS76_RS23595 () | 98933..99358 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| LOS76_RS23600 () | 99405..99827 | + | 423 | WP_000271762.1 | DUF1380 family protein | - |
| LOS76_RS23605 () | 99824..100015 | + | 192 | WP_001027493.1 | hypothetical protein | - |
| LOS76_RS23610 () | 101053..101283 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| LOS76_RS23615 () | 101335..102696 | + | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| LOS76_RS23620 () | 102743..103306 | + | 564 | WP_015059007.1 | class I SAM-dependent methyltransferase | - |
| LOS76_RS23625 () | 103392..103859 | - | 468 | Protein_125 | hypothetical protein | - |
| LOS76_RS23630 () | 104161..104700 | + | 540 | WP_000290791.1 | single-stranded DNA-binding protein | - |
| LOS76_RS23635 () | 104763..104996 | + | 234 | WP_000005990.1 | DUF905 family protein | - |
| LOS76_RS23640 () | 105062..107020 | + | 1959 | WP_023148339.1 | ParB/RepB/Spo0J family partition protein | - |
| LOS76_RS23645 () | 107075..107509 | + | 435 | WP_000845934.1 | conjugation system SOS inhibitor PsiB | - |
| LOS76_RS23650 () | 107506..108268 | + | 763 | Protein_130 | plasmid SOS inhibition protein A | - |
| LOS76_RS23655 () | 108237..108425 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - () | 108237..108461 | + | 225 | NuclAT_0 | - | - |
| - () | 108237..108461 | + | 225 | NuclAT_0 | - | - |
| - () | 108237..108461 | + | 225 | NuclAT_0 | - | - |
| - () | 108237..108461 | + | 225 | NuclAT_0 | - | - |
| - | 108394..108459 | - | 66 | - | - | Antitoxin Detail |
| LOS76_RS23660 () | 108447..108596 | + | 150 | Protein_132 | plasmid maintenance protein Mok | - |
| LOS76_RS23665 () | 108538..108663 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| LOS76_RS23670 () | 108883..109113 | + | 231 | WP_071587244.1 | hypothetical protein | - |
| LOS76_RS23675 () | 109111..109284 | - | 174 | Protein_135 | hypothetical protein | - |
| LOS76_RS23680 () | 109354..109560 | + | 207 | WP_000547939.1 | hypothetical protein | - |
| LOS76_RS23685 () | 109585..109872 | + | 288 | WP_000107535.1 | hypothetical protein | - |
| LOS76_RS23690 () | 109994..110815 | + | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| LOS76_RS23695 () | 111112..111714 | - | 603 | WP_000243709.1 | hypothetical protein | VF |
| LOS76_RS23700 () | 112035..112418 | + | 384 | WP_053320747.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| LOS76_RS23705 () | 112605..113294 | + | 690 | WP_000283380.1 | conjugal transfer transcriptional regulator TraJ | - |
| LOS76_RS23710 () | 113387..113788 | + | 402 | WP_223349250.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| LOS76_RS23715 () | 113821..114183 | + | 363 | WP_000994784.1 | type IV conjugative transfer system pilin TraA | - |
| LOS76_RS23720 () | 114188..114499 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| LOS76_RS23725 () | 114521..115087 | + | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| LOS76_RS23730 () | 115074..115802 | + | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| LOS76_RS23735 () | 115802..117229 | + | 1428 | WP_000146672.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| LOS76_RS23740 () | 117219..117806 | + | 588 | WP_053320746.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| LOS76_RS23745 () | 117793..118113 | + | 321 | WP_001057285.1 | conjugal transfer protein TrbD | - |
| LOS76_RS23750 () | 118110..118625 | + | 516 | WP_000724019.1 | type IV conjugative transfer system lipoprotein TraV | - |
| LOS76_RS23755 () | 118760..118981 | + | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| LOS76_RS23760 () | 119141..121768 | + | 2628 | WP_231364125.1 | type IV secretion system protein TraC | - |
| LOS76_RS23765 () | 121765..122151 | + | 387 | WP_000099687.1 | type-F conjugative transfer system protein TrbI | - |
| LOS76_RS23770 () | 122148..122780 | + | 633 | WP_001749440.1 | type-F conjugative transfer system protein TraW | - |
| LOS76_RS23775 () | 122777..123769 | + | 993 | WP_053320745.1 | conjugal transfer pilus assembly protein TraU | - |
| LOS76_RS23780 () | 123778..124416 | + | 639 | WP_072668260.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| LOS76_RS23785 () | 124413..126221 | + | 1809 | WP_000821845.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| LOS76_RS23790 () | 126248..126508 | + | 261 | WP_000864348.1 | conjugal transfer protein TrbE | - |
| LOS76_RS23795 () | 126501..127244 | + | 744 | WP_001030376.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| LOS76_RS23800 () | 127405..127641 | + | 237 | WP_001346259.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| LOS76_RS23805 () | 127628..128173 | + | 546 | WP_000052618.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| LOS76_RS23810 () | 128103..128465 | + | 363 | WP_001443292.1 | P-type conjugative transfer protein TrbJ | - |
| LOS76_RS23815 () | 128465..129838 | + | 1374 | WP_065800514.1 | conjugal transfer pilus assembly protein TraH | - |
| LOS76_RS23820 () | 129835..132657 | + | 2823 | WP_053320755.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| LOS76_RS23825 () | 132672..133175 | + | 504 | WP_053320762.1 | surface exclusion protein | - |
| LOS76_RS23830 () | 133207..133938 | + | 732 | WP_000850424.1 | conjugal transfer complement resistance protein TraT | - |
| LOS76_RS23835 () | 134191..136416 | + | 2226 | WP_100620352.1 | type IV conjugative transfer system coupling protein TraD | - |
| LOS76_RS23840 () | 136416..141686 | + | 5271 | WP_053320757.1 | Multifunctional conjugation protein TraI | Relaxase |
| LOS76_RS23845 () | 141706..142449 | + | 744 | WP_000205704.1 | conjugal transfer pilus acetylase TraX | - |
| LOS76_RS23850 () | 142504..143064 | + | 561 | WP_024184455.1 | fertility inhibition protein FinO | - |
| LOS76_RS23855 () | 143200..143412 | + | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| LOS76_RS23860 () | 143507..143695 | + | 189 | WP_112919699.1 | hypothetical protein | - |
| LOS76_RS23865 () | 143698..146247 | + | 2550 | WP_053320758.1 | DEAD/DEAH box helicase family protein | - |
| LOS76_RS23870 () | 146293..148326 | + | 2034 | WP_000887497.1 | N-6 DNA methylase | - |
| LOS76_RS23875 () | 148391..151246 | + | 2856 | WP_053320759.1 | chromosome segregation protein SMC | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|