MGE detailed information
MGE type: Conjugative plasmid MGE length: 128397 bp
Accession: NZ_CP087565 Location: 1..128397 Organism: Escherichia coli strain CM2010-0578/1 Replicon: plasmid p10_578_1
Accession: NZ_CP087565 Location: 1..128397 Organism: Escherichia coli strain CM2010-0578/1 Replicon: plasmid p10_578_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LOF66_RS24865 (1) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| LOF66_RS24870 (1263) | 1263..2003 | - | 741 | WP_001066953.1 | tyrosine-type recombinase/integrase | - |
| LOF66_RS24875 (2124) | 2124..2312 | - | 189 | WP_001312821.1 | hypothetical protein | - |
| LOF66_RS24880 (2686) | 2686..3594 | - | 909 | Protein_3 | antimicrobial resistance protein Mig-14 | - |
| LOF66_RS24885 (3667) | 3667..4773 | - | 1107 | Protein_4 | SDR family oxidoreductase | - |
| LOF66_RS24890 (5205) | 5205..6158 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| LOF66_RS24895 (7408) | 7408..7715 | - | 308 | Protein_6 | IS3 family transposase IS1351 | Transposase |
| LOF66_RS24900 (7770) | 7770..8060 | + | 291 | Protein_7 | IS3 family transposase IS1203 | Transposase |
| LOF66_RS24905 (8128) | 8128..8824 | + | 697 | WP_001390273.1 | IS1 family transposase IS1R | Transposase |
| LOF66_RS24910 (8936) | 8936..9085 | - | 150 | Protein_9 | IS3 family transposase IS2 | Transposase |
| LOF66_RS24915 (9263) | 9263..10456 | - | 1194 | WP_000450494.1 | GTP-binding protein | - |
| LOF66_RS24920 (11679) | 11679..12915 | - | 1237 | Protein_11 | IS3 family transposase IS2 | Transposase |
| LOF66_RS24925 (13542) | 13542..13835 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| LOF66_RS24930 (13893) | 13893..14092 | - | 200 | Protein_13 | lysis protein | - |
| LOF66_RS24935 (14646) | 14646..15669 | + | 1024 | Protein_14 | IS481 family transposase ISKpn28 | Transposase |
| LOF66_RS24940 (16980) | 16980..18095 | + | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| LOF66_RS24945 (18235) | 18235..21894 | + | 3660 | WP_001111199.1 | Multidrug efflux ATP-binding/permease protein | VF |
| LOF66_RS24950 (21998) | 21998..23227 | + | 1230 | WP_000933675.1 | Enterochelin esterase | VF |
| LOF66_RS24955 (23312) | 23312..24268 | + | 957 | WP_274480486.1 | Ferri-bacillibactin esterase BesA | VF |
| LOF66_RS24960 (24313) | 24313..26490 | - | 2178 | WP_094317250.1 | Ferric enterobactin receptor | VF |
| LOF66_RS24965 (26952) | 26952..27656 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LOF66_RS24970 (27647) | 27647..27835 | + | 189 | WP_181821230.1 | hypothetical protein | - |
| LOF66_RS24975 (27864) | 27864..28561 | + | 698 | WP_223411729.1 | IS1 family transposase IS1S | Transposase |
| LOF66_RS24980 (28577) | 28577..29899 | + | 1323 | Protein_23 | Toxin RTX-I translocation ATP-binding protein | VF |
| LOF66_RS24985 (30069) | 30069..30380 | - | 312 | WP_001259758.1 | colicin V | - |
| LOF66_RS24990 (30358) | 30358..30597 | - | 240 | Protein_25 | colicin V immunity protein | - |
| LOF66_RS24995 (31139) | 31139..31342 | - | 204 | Protein_26 | hypothetical protein | - |
| LOF66_RS25000 (31515) | 31515..31682 | + | 168 | Protein_27 | colicin-B | - |
| LOF66_RS25005 (31700) | 31700..32227 | - | 528 | WP_000203272.1 | colicin B immunity protein | - |
| LOF66_RS25010 (32471) | 32471..33286 | + | 816 | WP_032494162.1 | lipid II-degrading bacteriocin colicin M | - |
| LOF66_RS25015 (33336) | 33336..33690 | - | 355 | Protein_30 | colicin M immunity protein | - |
| LOF66_RS25020 (33869) | 33869..34660 | - | 792 | WP_000016493.1 | site-specific integrase | - |
| LOF66_RS25025 (34657) | 34657..35346 | - | 690 | WP_000796228.1 | hypothetical protein | - |
| LOF66_RS25030 (35390) | 35390..35740 | - | 351 | WP_000493379.1 | hypothetical protein | - |
| LOF66_RS25035 (36302) | 36302..36532 | + | 231 | WP_001261278.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| LOF66_RS25040 (36529) | 36529..36945 | + | 417 | WP_001034046.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| LOF66_RS25045 (36990) | 36990..40784 | - | 3795 | WP_001144732.1 | hypothetical protein | - |
| LOF66_RS25050 (41097) | 41097..41354 | + | 258 | WP_171929857.1 | hypothetical protein | - |
| LOF66_RS25055 (41354) | 41354..41965 | + | 612 | WP_171929858.1 | hypothetical protein | - |
| LOF66_RS25060 (42054) | 42054..42434 | + | 381 | WP_001171554.1 | IS66 family transposase ISEc8 | Transposase |
| LOF66_RS25065 (42431) | 42431..42778 | + | 348 | WP_000612591.1 | IS66 family transposase ISEc8 | Transposase |
| LOF66_RS25070 (42828) | 42828..44366 | + | 1539 | WP_264831155.1 | IS66 family transposase ISEc8 | Transposase |
| LOF66_RS25075 (44489) | 44489..44701 | - | 213 | WP_097330523.1 | hypothetical protein | - |
| LOF66_RS25080 (44892) | 44892..45071 | + | 180 | Protein_43 | ATP-binding protein | - |
| LOF66_RS25085 (45141) | 45141..45332 | - | 192 | Protein_44 | IS3 family transposase | - |
| LOF66_RS25090 (45418) | 45418..45690 | + | 273 | WP_113383268.1 | hypothetical protein | - |
| LOF66_RS25095 (45671) | 45671..46879 | + | 1209 | WP_113383269.1 | IS91 family transposase ISSbo1 | Transposase |
| LOF66_RS25100 (47156) | 47156..47275 | + | 120 | Protein_47 | IS91 family transposase | - |
| LOF66_RS25105 (47564) | 47564..51433 | - | 3870 | WP_274480487.1 | putative autotransporter | VF |
| LOF66_RS25110 (51417) | 51417..52646 | - | 1230 | WP_274480488.1 | autotransporter strand-loop-strand O-heptosyltransferase | - |
| LOF66_RS25115 (53512) | 53512..53784 | - | 273 | WP_265751832.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| LOF66_RS25120 (53915) | 53915..55084 | - | 1170 | WP_274480489.1 | IS91 family transposase IS1294 | Transposase |
| LOF66_RS25125 (55192) | 55192..55380 | + | 189 | WP_000957857.1 | hypothetical protein | - |
| LOF66_RS25130 (55390) | 55390..56589 | + | 1200 | WP_274480483.1 | IS91 family transposase ISSbo1 | Transposase |
| LOF66_RS25135 (56812) | 56812..57000 | - | 189 | WP_000957857.1 | hypothetical protein | - |
| LOF66_RS25140 (57177) | 57177..57440 | - | 264 | WP_058649686.1 | hypothetical protein | - |
| LOF66_RS25145 (57460) | 57460..57741 | - | 282 | WP_058649687.1 | helix-turn-helix transcriptional regulator | - |
| LOF66_RS25150 (57722) | 57722..58051 | - | 330 | WP_058649688.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| LOF66_RS25155 (58988) | 58988..59845 | - | 858 | WP_000130940.1 | incFII family plasmid replication initiator RepA | - |
| LOF66_RS25160 (59838) | 59838..59885 | - | 48 | WP_077822033.1 | hypothetical protein | - |
| LOF66_RS25165 (59876) | 59876..60112 | + | 237 | WP_223368648.1 | replication protein RepA | - |
| LOF66_RS25170 (60138) | 60138..60398 | - | 261 | WP_000083818.1 | replication regulatory protein RepA | - |
| LOF66_RS25175 (60637) | 60637..61210 | - | 574 | Protein_62 | DUF2726 domain-containing protein | - |
| LOF66_RS25180 (61248) | 61248..61457 | - | 210 | WP_001333231.1 | hemolysin expression modulator Hha | - |
| LOF66_RS25185 (61503) | 61503..61964 | - | 462 | WP_001233871.1 | thermonuclease family protein | - |
| LOF66_RS25190 (62207) | 62207..62419 | - | 213 | WP_012311405.1 | hypothetical protein | - |
| LOF66_RS25195 (62557) | 62557..63117 | - | 561 | WP_000139359.1 | fertility inhibition protein FinO | - |
| LOF66_RS25200 (63172) | 63172..63918 | - | 747 | WP_000205777.1 | conjugal transfer pilus acetylase TraX | - |
| LOF66_RS25205 (63938) | 63938..69208 | - | 5271 | WP_113931169.1 | Multifunctional conjugation protein TraI | Relaxase |
| LOF66_RS25210 (69208) | 69208..71379 | - | 2172 | WP_274480480.1 | type IV conjugative transfer system coupling protein TraD | - |
| LOF66_RS25215 (71631) | 71631..72362 | - | 732 | WP_000850424.1 | conjugal transfer complement resistance protein TraT | - |
| LOF66_RS25220 (72431) | 72431..72886 | - | 456 | WP_274480481.1 | conjugal transfer entry exclusion protein TraS | - |
| LOF66_RS25225 (72883) | 72883..75708 | - | 2826 | WP_274480482.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| LOF66_RS25230 (75705) | 75705..77078 | - | 1374 | WP_001137358.1 | conjugal transfer pilus assembly protein TraH | - |
| LOF66_RS25235 (77078) | 77078..77440 | - | 363 | WP_002430925.1 | P-type conjugative transfer protein TrbJ | - |
| LOF66_RS25240 (77370) | 77370..77915 | - | 546 | WP_000052618.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| LOF66_RS25245 (77902) | 77902..78186 | - | 285 | WP_000624110.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| LOF66_RS25250 (78305) | 78305..78652 | - | 348 | WP_001287677.1 | conjugal transfer protein TrbA | - |
| LOF66_RS25255 (78668) | 78668..79411 | - | 744 | WP_001030376.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| LOF66_RS25260 (79404) | 79404..79661 | - | 258 | WP_000864325.1 | conjugal transfer protein TrbE | - |
| LOF66_RS25265 (79688) | 79688..81496 | - | 1809 | WP_001567342.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| LOF66_RS25270 (81493) | 81493..82131 | - | 639 | WP_059277995.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| LOF66_RS25275 (82140) | 82140..83132 | - | 993 | WP_001712363.1 | conjugal transfer pilus assembly protein TraU | - |
| LOF66_RS25280 (83129) | 83129..83761 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| LOF66_RS25285 (83758) | 83758..84144 | - | 387 | WP_000099690.1 | type-F conjugative transfer system protein TrbI | - |
| LOF66_RS25290 (84141) | 84141..86771 | - | 2631 | WP_000069766.1 | type IV secretion system protein TraC | - |
| LOF66_RS25295 (86898) | 86898..87245 | - | 348 | WP_000802783.1 | hypothetical protein | - |
| LOF66_RS25300 (87273) | 87273..87490 | - | 218 | Protein_87 | hypothetical protein | - |
| LOF66_RS25305 (87570) | 87570..88046 | - | 477 | WP_000549579.1 | hypothetical protein | - |
| LOF66_RS25310 (88039) | 88039..88260 | - | 222 | WP_113931172.1 | conjugal transfer protein TraR | - |
| LOF66_RS25315 (88395) | 88395..88910 | - | 516 | WP_113931173.1 | type IV conjugative transfer system lipoprotein TraV | - |
| LOF66_RS25320 (88907) | 88907..89227 | - | 321 | WP_001057307.1 | conjugal transfer protein TrbD | - |
| LOF66_RS25325 (89214) | 89214..89804 | - | 591 | WP_000002784.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| LOF66_RS25330 (89794) | 89794..91221 | - | 1428 | WP_000146657.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| LOF66_RS25335 (91221) | 91221..91949 | - | 729 | WP_001230798.1 | type-F conjugative transfer system secretin TraK | - |
| LOF66_RS25340 (91936) | 91936..92502 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| LOF66_RS25345 (92524) | 92524..92835 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| LOF66_RS25350 (92850) | 92850..93209 | - | 360 | WP_000340272.1 | type IV conjugative transfer system pilin TraA | - |
| LOF66_RS25355 (93243) | 93243..93470 | - | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| LOF66_RS25360 (93564) | 93564..94250 | - | 687 | WP_000332484.1 | PAS domain-containing protein | - |
| LOF66_RS25365 (94441) | 94441..94824 | - | 384 | WP_000124981.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| LOF66_RS25370 (95101) | 95101..95748 | + | 648 | WP_133301285.1 | hypothetical protein | VF |
| LOF66_RS25375 (96045) | 96045..96866 | - | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| LOF66_RS25380 (96987) | 96987..97274 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| LOF66_RS25385 (97299) | 97299..97505 | - | 207 | WP_000547939.1 | hypothetical protein | - |
| LOF66_RS25390 (97575) | 97575..97748 | + | 174 | Protein_105 | hypothetical protein | - |
| LOF66_RS25395 (97746) | 97746..97976 | - | 231 | WP_071587244.1 | hypothetical protein | - |
| LOF66_RS25400 (98196) | 98196..98321 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| LOF66_RS25405 (98263) | 98263..98412 | - | 150 | Protein_108 | plasmid maintenance protein Mok | - |
| - (98398) | 98398..98622 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (98398) | 98398..98622 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (98398) | 98398..98622 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (98398) | 98398..98622 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| LOF66_RS25410 (98434) | 98434..98622 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| LOF66_RS25415 (98591) | 98591..99353 | - | 763 | Protein_110 | plasmid SOS inhibition protein A | - |
| LOF66_RS25420 (99350) | 99350..99784 | - | 435 | WP_000845901.1 | conjugation system SOS inhibitor PsiB | - |
| LOF66_RS25425 (99839) | 99839..101797 | - | 1959 | WP_001145469.1 | ParB/RepB/Spo0J family partition protein | - |
| LOF66_RS25430 (101856) | 101856..102089 | - | 234 | WP_000006004.1 | DUF905 domain-containing protein | - |
| LOF66_RS25435 (102145) | 102145..102672 | - | 528 | WP_000290793.1 | single-stranded DNA-binding protein | - |
| LOF66_RS25440 (103145) | 103145..103423 | - | 279 | WP_072127934.1 | hypothetical protein | - |
| LOF66_RS25445 (103315) | 103315..103575 | - | 261 | WP_021536188.1 | hypothetical protein | - |
| LOF66_RS25450 (103575) | 103575..104138 | - | 564 | WP_001311069.1 | class I SAM-dependent methyltransferase | - |
| LOF66_RS25455 (104184) | 104184..105545 | - | 1362 | WP_113931190.1 | DUF3560 domain-containing protein | - |
| LOF66_RS25460 (105597) | 105597..105827 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| LOF66_RS25465 (106175) | 106175..106363 | + | 189 | WP_000957857.1 | hypothetical protein | - |
| LOF66_RS25470 (106373) | 106373..107572 | + | 1200 | WP_274480483.1 | IS91 family transposase ISSbo1 | Transposase |
| LOF66_RS25475 (108032) | 108032..108285 | + | 254 | Protein_122 | hypothetical protein | - |
| LOF66_RS25480 (108509) | 108509..108691 | - | 183 | WP_001027505.1 | hypothetical protein | - |
| LOF66_RS25485 (108691) | 108691..109152 | - | 462 | WP_123004564.1 | DUF1380 family protein | - |
| LOF66_RS25490 (109152) | 109152..109577 | - | 426 | WP_001198922.1 | antirestriction protein | - |
| LOF66_RS25495 (109979) | 109979..110950 | + | 972 | WP_274480484.1 | IS110 family transposase ISEc32 | Transposase |
| LOF66_RS25500 (111211) | 111211..111423 | - | 213 | WP_000092896.1 | hypothetical protein | - |
| LOF66_RS25505 (111436) | 111436..111630 | - | 195 | WP_231532840.1 | hypothetical protein | - |
| LOF66_RS25515 (112453) | 112453..112788 | - | 336 | WP_000343070.1 | hypothetical protein | - |
| LOF66_RS25520 (112857) | 112857..113204 | - | 348 | WP_001350917.1 | hypothetical protein | - |
| LOF66_RS25525 (113201) | 113201..113370 | - | 170 | Protein_132 | hypothetical protein | - |
| LOF66_RS25530 (114222) | 114222..115193 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| LOF66_RS25535 (115193) | 115193..116359 | - | 1167 | WP_001238646.1 | Sporulation initiation inhibitor protein Soj | VF |
| LOF66_RS25545 (118227) | 118227..119018 | - | 792 | WP_274480485.1 | hypothetical protein | - |
| LOF66_RS25550 (119637) | 119637..120062 | - | 426 | WP_012300440.1 | hypothetical protein | - |
| LOF66_RS25555 (120204) | 120204..120683 | + | 480 | WP_000190053.1 | hypothetical protein | - |
| LOF66_RS25560 (121123) | 121123..121374 | + | 252 | WP_000163248.1 | hypothetical protein | - |
| LOF66_RS25565 (121347) | 121347..121478 | - | 132 | Protein_140 | phosphopyruvate hydratase | - |
| LOF66_RS25570 (121476) | 121476..121733 | + | 258 | Protein_141 | Tn3 family transposase | - |
| LOF66_RS25575 (121967) | 121967..122824 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| LOF66_RS25580 (122821) | 122821..123678 | - | 858 | WP_000992806.1 | Manganese transport system membrane protein MntB | ARG |
| LOF66_RS25585 (123675) | 123675..124502 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| LOF66_RS25590 (124502) | 124502..125416 | - | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| LOF66_RS25595 (125772) | 125772..126469 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| LOF66_RS25600 (126649) | 126649..127162 | - | 514 | Protein_147 | DUF4113 domain-containing protein | - |
| LOF66_RS25605 (127223) | 127223..127327 | - | 105 | Protein_148 | AAA family ATPase | - |
| LOF66_RS25610 (127329) | 127329..127652 | - | 324 | Protein_149 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|