NZ_CP0873781..147403

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 147403 bp
Accession: NZ_CP087378        Location: 1..147403         Organism: Escherichia coli strain RIVM_C019217       Replicon: plasmid pRIVM_C019217_2


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LN359_RS25365 (1) 1..978 + 978 WP_001309253.1 RepB family plasmid replication initiator protein -
LN359_RS25370 (1221) 1221..1961 - 741 WP_001066941.1 tyrosine-type recombinase/integrase -
LN359_RS25375 (2082) 2082..2264 - 183 WP_042344623.1 hypothetical protein -
LN359_RS25380 (2331) 2331..2621 - 291 Protein_3 type II toxin-antitoxin system RelE/ParE family toxin -
LN359_RS25385 (2608) 2608..2876 - 269 Protein_4 type II toxin-antitoxin system ParD family antitoxin -
LN359_RS25390 (3408) 3408..4577 + 1170 WP_001403369.1 hypothetical protein -
LN359_RS25395 (4610) 4610..4738 + 129 Protein_6 IS481 family transposase -
LN359_RS25400 (4863) 4863..5066 - 204 Protein_7 hypothetical protein -
LN359_RS25405 (5172) 5172..5447 - 276 WP_000421273.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin Detail
LN359_RS25410 (5447) 5447..5731 - 285 WP_001387467.1 ribbon-helix-helix domain-containing protein Antitoxin Detail
LN359_RS25415 (6336) 6336..7088 + 753 WP_001403368.1 IclR family transcriptional regulator -
LN359_RS25420 (7134) 7134..8099 - 966 WP_001022265.1 2-keto-3-deoxygluconate transporter -
LN359_RS25425 (8132) 8132..8512 - 381 WP_000710783.1 Rid family detoxifying hydrolase -
LN359_RS25430 (8537) 8537..9427 - 891 WP_001077068.1 dihydrodipicolinate synthase family protein -
LN359_RS25435 (9780) 9780..10346 + 567 Protein_14 zinc-binding dehydrogenase -
LN359_RS25440 (10477) 10477..11355 + 879 WP_162753243.1 sugar ABC transporter permease -
LN359_RS25445 (11345) 11345..12232 + 888 WP_001271561.1 carbohydrate ABC transporter permease -
LN359_RS25450 (12243) 12243..13067 + 825 WP_000922702.1 phosphodiesterase -
LN359_RS25455 (13073) 13073..14146 + 1074 WP_000950177.1 sn-glycerol-3-phosphate import ATP-binding protein UgpC VF
LN359_RS25460 (14139) 14139..15449 + 1311 WP_000476108.1 ABC transporter substrate-binding protein -
LN359_RS25465 (15508) 15508..15816 - 309 Protein_20 IS4 family transposase ISEc13 Transposase
LN359_RS25470 (15893) 15893..16108 - 216 Protein_21 Tn3 family transposase -
LN359_RS25475 (16163) 16163..17376 + 1214 Protein_22 IS3 family transposase -
- (17544) 17544..17598 + 55 NuclAT_1 - -
- (17544) 17544..17598 + 55 NuclAT_1 - -
- (17544) 17544..17598 + 55 NuclAT_1 - -
- (17544) 17544..17598 + 55 NuclAT_1 - -
LN359_RS25480 (17875) 17875..19239 - 1365 WP_077758488.1 MFS transporter -
LN359_RS25485 (19357) 19357..20424 - 1068 WP_032248209.1 cellulase family glycosylhydrolase -
LN359_RS25490 (20759) 20759..21987 + 1229 WP_141427546.1 IS3 family transposase IS2 Transposase
LN359_RS25495 (22296) 22296..23333 + 1038 WP_032248218.1 LacI family DNA-binding transcriptional regulator -
LN359_RS25500 (23387) 23387..23671 - 285 Protein_27 integrase core domain-containing protein -
LN359_RS25505 (23726) 23726..24430 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LN359_RS25510 (24495) 24495..24674 + 180 Protein_29 IS1380 family transposase -
LN359_RS25515 (24924) 24924..25799 + 876 WP_032277257.1 Beta-lactamase CTX-M-97 ARG
LN359_RS25520 (25941) 25941..26645 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LN359_RS25525 (26698) 26698..27204 + 507 Protein_32 transposase -
LN359_RS25530 (27213) 27213..28073 + 861 WP_000493383.1 EamA family transporter -
LN359_RS25535 (28105) 28105..29304 - 1200 WP_000804064.1 Tetracycline resistance protein, class C ARG
LN359_RS25540 (29410) 29410..30036 + 627 WP_031606906.1 tetracycline resistance transcriptional repressor TetR(A) -
LN359_RS25545 (30068) 30068..30304 - 237 WP_042005022.1 hypothetical protein -
LN359_RS25550 (30358) 30358..31194 - 837 WP_000480972.1 hypothetical protein ARG
LN359_RS25555 (31194) 31194..31997 - 804 WP_001082319.1 Aminoglycoside 3'-phosphotransferase ARG
LN359_RS25560 (32058) 32058..32873 - 816 WP_001043260.1 Dihydropteroate synthase ARG
LN359_RS25565 (33181) 33181..33357 - 177 Protein_40 replication protein C, IncQ-type -
LN359_RS25570 (33418) 33418..34122 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LN359_RS25575 (34244) 34244..35149 + 906 WP_000219391.1 hypothetical protein ARG
LN359_RS25580 (35146) 35146..36384 + 1239 WP_000004159.1 macrolide resistance MFS transporter Mrx(A) -
LN359_RS25585 (36384) 36384..36968 + 585 WP_001137892.1 macrolide-binding transcriptional repressor MphR(A) -
LN359_RS25590 (37461) 37461..38225 - 765 WP_001389365.1 IS6 family transposase IS6100 Transposase
LN359_RS25595 (38343) 38343..38408 - 66 Protein_46 EAL domain-containing protein -
LN359_RS25600 (38452) 38452..38757 - 306 WP_000130000.1 hypothetical protein Relaxase
LN359_RS25605 (38768) 38768..39973 - 1206 WP_000184001.1 chromate efflux transporter -
LN359_RS25610 (40129) 40129..40332 - 204 WP_000376616.1 hypothetical protein -
LN359_RS25615 (40460) 40460..41299 - 840 WP_000259031.1 Dihydropteroate synthase ARG
LN359_RS25620 (41293) 41293..41640 - 348 WP_000679427.1 Multidrug transporter EmrE ARG
LN359_RS25625 (41846) 41846..42634 - 789 WP_000503573.1 Streptomycin 3''-adenylyltransferase ARG
LN359_RS25630 (42765) 42765..43238 - 474 WP_001389366.1 Dihydrofolate reductase type 1 ARG
LN359_RS25635 (43396) 43396..44145 + 750 Protein_54 IS91 family transposase ISAzo26 Transposase
LN359_RS25640 (44204) 44204..44908 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LN359_RS25645 (44958) 44958..45176 - 219 Protein_56 IS4 family transposase -
LN359_RS25655 (46088) 46088..46201 + 114 Protein_58 IS6 family transposase IS15DI Transposase
LN359_RS25660 (46339) 46339..46509 + 171 Protein_59 DsbA family protein -
LN359_RS25665 (46499) 46499..47005 + 507 WP_000949452.1 protein disulfide oxidoreductase -
LN359_RS25670 (47242) 47242..48003 + 762 WP_001225378.1 Na(+)-translocating NADH-quinone reductase subunit C -
LN359_RS25675 (48350) 48350..50236 + 1887 WP_192514405.1 FTR1 family protein -
LN359_RS25680 (50277) 50277..50804 + 528 WP_000178050.1 iron transporter -
LN359_RS25685 (50908) 50908..52287 + 1380 WP_000119836.1 Fe-S-containing protein -
LN359_RS25690 (52290) 52290..53573 + 1284 WP_000964653.1 ABC transporter permease -
LN359_RS25695 (53563) 53563..54693 + 1131 WP_000729219.1 ABC transporter permease -
LN359_RS25700 (54698) 54698..55393 + 696 WP_063624982.1 Lipoprotein-releasing system ATP-binding protein LolD VF
LN359_RS25705 (55380) 55380..55865 + 486 WP_001554949.1 TlpA disulfide reductase family protein -
LN359_RS25710 (55890) 55890..56375 + 486 WP_000874189.1 hypothetical protein -
LN359_RS25715 (56497) 56497..57129 + 633 Protein_70 histidine-type phosphatase -
LN359_RS25720 (57279) 57279..58259 - 981 WP_063624983.1 IS5 family transposase ISKpn26 Transposase
LN359_RS25725 (58355) 58355..59542 - 1188 WP_162753250.1 MFS transporter -
LN359_RS25730 (59599) 59599..60360 - 762 WP_000020504.1 Fe(3+) dicitrate transport ATP-binding protein FecE VF
LN359_RS25735 (60360) 60360..61397 - 1038 WP_032248242.1 Hemin transport system permease protein HmuU VF
LN359_RS25740 (61397) 61397..62395 - 999 WP_004175650.1 ABC transporter substrate-binding protein -
LN359_RS25745 (62545) 62545..62649 - 105 Protein_76 integrase core domain-containing protein -
LN359_RS25750 (62797) 62797..63501 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LN359_RS25755 (63618) 63618..64637 - 1020 WP_077758491.1 nucleoside hydrolase -
LN359_RS25760 (64612) 64612..65643 - 1032 WP_000194408.1 LacI family DNA-binding transcriptional regulator -
LN359_RS25765 (65749) 65749..67143 - 1395 WP_050488426.1 MFS transporter -
LN359_RS25770 (67341) 67341..67472 - 132 Protein_81 Rpn family recombination-promoting nuclease/putative transposase -
LN359_RS25775 (67746) 67746..68126 + 381 WP_000621515.1 aspartate 1-decarboxylase -
LN359_RS25780 (68130) 68130..68370 - 241 Protein_83 polysaccharide deacetylase family protein -
LN359_RS25785 (68449) 68449..68523 + 75 Protein_84 hypothetical protein -
LN359_RS25790 (68668) 68668..69519 - 852 WP_032248272.1 pantoate--beta-alanine ligase -
LN359_RS25795 (69531) 69531..70325 - 795 WP_063625815.1 3-methyl-2-oxobutanoate hydroxymethyltransferase -
LN359_RS25800 (70464) 70464..71384 + 921 Protein_87 IS4 family transposase IS4 Transposase
LN359_RS25805 (71504) 71504..72434 + 931 Protein_88 IS3 family transposase -
LN359_RS25810 (72501) 72501..73205 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LN359_RS25815 (73271) 73271..73816 + 546 Protein_90 Tn3 family transposase TnpA_Tn3 Transposase
LN359_RS25820 (73852) 73852..74267 - 416 Protein_91 IS1-like element IS1B family transposase -
LN359_RS25825 (74516) 74516..74917 - 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
LN359_RS25830 (74850) 74850..75107 - 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
LN359_RS25835 (75200) 75200..75853 - 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
LN359_RS25840 (76792) 76792..77649 - 858 WP_000130647.1 incFII family plasmid replication initiator RepA -
LN359_RS25845 (77642) 77642..77716 - 75 WP_001365705.1 RepA leader peptide Tap -
LN359_RS25850 (77941) 77941..78201 - 261 WP_000083819.1 replication regulatory protein RepA -
LN359_RS25855 (78441) 78441..79031 - 591 WP_000766805.1 DUF2726 domain-containing protein -
LN359_RS25860 (79069) 79069..79278 - 210 WP_001298565.1 hemolysin expression modulator Hha -
LN359_RS25865 (79324) 79324..79644 - 321 Protein_100 thermonuclease family protein -
LN359_RS25870 (79676) 79676..81289 - 1614 WP_135118410.1 IS66 family transposase ISEc23 Transposase
LN359_RS25875 (81320) 81320..81670 - 351 WP_000624722.1 IS66 family transposase ISEc23 Transposase
LN359_RS25880 (81667) 81667..82092 - 426 WP_000422741.1 IS66 family transposase ISEc23 Transposase
LN359_RS25885 (82182) 82182..82325 - 144 Protein_104 endonuclease -
LN359_RS25890 (82570) 82570..82782 - 213 WP_001309245.1 ANR family transcriptional regulator -
LN359_RS25895 (82911) 82911..83471 - 561 WP_000139321.1 fertility inhibition protein FinO -
LN359_RS25900 (83574) 83574..84434 - 861 WP_000704523.1 putative protein YcjY VF
LN359_RS25905 (84493) 84493..85239 - 747 WP_000205725.1 conjugal transfer pilus acetylase TraX -
LN359_RS25910 (85259) 85259..90529 - 5271 WP_230230724.1 Multifunctional conjugation protein TraI Relaxase
LN359_RS25915 (90529) 90529..92727 - 2199 WP_186173458.1 type IV conjugative transfer system coupling protein TraD -
LN359_RS25920 (92980) 92980..93711 - 732 WP_024221017.1 conjugal transfer complement resistance protein TraT -
LN359_RS25925 (93743) 93743..94240 - 498 WP_000605861.1 hypothetical protein -
LN359_RS25930 (94259) 94259..97078 - 2820 WP_229327589.1 conjugal transfer mating-pair stabilization protein TraG -
LN359_RS25935 (97075) 97075..98448 - 1374 WP_001137364.1 conjugal transfer pilus assembly protein TraH -
LN359_RS25940 (98435) 98435..98827 - 393 WP_000660703.1 F-type conjugal transfer protein TrbF -
LN359_RS25945 (98808) 98808..99149 - 342 WP_001448115.1 P-type conjugative transfer protein TrbJ -
LN359_RS25950 (99079) 99079..99624 - 546 WP_000059824.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
LN359_RS25955 (99611) 99611..99895 - 285 WP_001448202.1 type-F conjugative transfer system pilin chaperone TraQ -
LN359_RS25960 (100022) 100022..100360 - 339 WP_001287905.1 conjugal transfer protein TrbA -
LN359_RS25965 (100376) 100376..101119 - 744 WP_001749618.1 type-F conjugative transfer system pilin assembly protein TraF -
LN359_RS25970 (101112) 101112..101369 - 258 WP_000864320.1 conjugal transfer protein TrbE -
LN359_RS25975 (101396) 101396..103204 - 1809 WP_024221016.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
LN359_RS25980 (103201) 103201..103839 - 639 WP_001080257.1 type-F conjugative transfer system pilin assembly protein TrbC -
LN359_RS25985 (103848) 103848..104153 - 306 WP_000224411.1 hypothetical protein -
LN359_RS25990 (104183) 104183..105175 - 993 WP_000830838.1 conjugal transfer pilus assembly protein TraU -
LN359_RS25995 (105172) 105172..105804 - 633 WP_001203720.1 type-F conjugative transfer system protein TraW -
LN359_RS26000 (105801) 105801..106187 - 387 WP_000214082.1 type-F conjugative transfer system protein TrbI -
LN359_RS26005 (106184) 106184..108810 - 2627 Protein_128 type IV secretion system protein TraC -
LN359_RS26010 (108970) 108970..109191 - 222 WP_001278978.1 conjugal transfer protein TraR -
LN359_RS26015 (109326) 109326..109841 - 516 WP_000809893.1 type IV conjugative transfer system lipoprotein TraV -
LN359_RS26020 (109838) 109838..110089 - 252 WP_001038341.1 conjugal transfer protein TrbG -
LN359_RS26025 (110082) 110082..110402 - 321 WP_001057302.1 conjugal transfer protein TrbD -
LN359_RS26030 (110389) 110389..110973 - 585 WP_000002795.1 conjugal transfer pilus-stabilizing protein TraP -
LN359_RS26035 (110963) 110963..112390 - 1428 WP_000146638.1 F-type conjugal transfer pilus assembly protein TraB -
LN359_RS26040 (112390) 112390..113118 - 729 WP_215200862.1 type-F conjugative transfer system secretin TraK -
LN359_RS26045 (113105) 113105..113671 - 567 WP_000399804.1 type IV conjugative transfer system protein TraE -
LN359_RS26050 (113693) 113693..114004 - 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
LN359_RS26055 (114009) 114009..114371 - 363 WP_001098998.1 type IV conjugative transfer system pilin TraA -
LN359_RS26060 (114405) 114405..114632 - 228 WP_001254388.1 conjugal transfer relaxosome protein TraY -
LN359_RS26065 (114726) 114726..115412 - 687 WP_000332487.1 PAS domain-containing protein -
LN359_RS26070 (115606) 115606..115989 - 384 WP_001151564.1 conjugal transfer relaxosome DNA-binding protein TraM -
LN359_RS26075 (116275) 116275..116922 + 648 WP_124760006.1 hypothetical protein VF
LN359_RS26080 (117219) 117219..118040 - 822 WP_001234469.1 DUF932 domain-containing protein -
LN359_RS26085 (118160) 118160..118447 - 288 WP_000107537.1 hypothetical protein -
LN359_RS26090 (118745) 118745..118918 + 174 Protein_145 hypothetical protein -
LN359_RS26095 (118916) 118916..119146 - 231 WP_071587244.1 hypothetical protein -
LN359_RS26100 (119366) 119366..119491 - 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
LN359_RS26105 (119433) 119433..119582 - 150 Protein_148 plasmid maintenance protein Mok -
- (119568) 119568..119792 - 225 NuclAT_0 - Antitoxin Detail
- (119568) 119568..119792 - 225 NuclAT_0 - Antitoxin Detail
- (119568) 119568..119792 - 225 NuclAT_0 - Antitoxin Detail
- (119568) 119568..119792 - 225 NuclAT_0 - Antitoxin Detail
LN359_RS26110 (119604) 119604..119792 + 189 WP_001299721.1 hypothetical protein -
LN359_RS26115 (119761) 119761..120523 - 763 Protein_150 plasmid SOS inhibition protein A -
LN359_RS26120 (120520) 120520..120954 - 435 WP_000845901.1 conjugation system SOS inhibitor PsiB -
LN359_RS26125 (121009) 121009..122967 - 1959 WP_229327587.1 ParB/RepB/Spo0J family partition protein -
LN359_RS26130 (123026) 123026..123259 - 234 WP_000006018.1 DUF905 domain-containing protein -
LN359_RS26135 (123315) 123315..123842 - 528 WP_000290793.1 single-stranded DNA-binding protein -
LN359_RS26140 (124312) 124312..124560 - 249 WP_071606928.1 hypothetical protein -
LN359_RS26145 (124482) 124482..124712 - 231 WP_001333093.1 hypothetical protein -
LN359_RS26150 (124712) 124712..125275 - 564 WP_001311069.1 class I SAM-dependent methyltransferase -
LN359_RS26155 (125322) 125322..126683 - 1362 WP_000170667.1 DUF3560 domain-containing protein -
LN359_RS26160 (126735) 126735..126965 - 231 WP_000155844.1 hypothetical protein -
LN359_RS26165 (127928) 127928..128119 - 192 WP_001027516.1 hypothetical protein -
LN359_RS26170 (128116) 128116..128538 - 423 WP_000271708.1 DUF1380 family protein -
LN359_RS26175 (128585) 128585..129010 - 426 WP_001198903.1 antirestriction protein -
LN359_RS26180 (129426) 129426..130196 - 771 WP_001004562.1 hypothetical protein -
LN359_RS26185 (130241) 130241..130759 - 519 WP_223364201.1 DUF1380 family protein -
LN359_RS26190 (130689) 130689..130910 - 222 WP_001104873.1 hypothetical protein -
LN359_RS26195 (130911) 130911..131594 - 684 WP_000086169.1 DNA methylase -
LN359_RS26200 (131670) 131670..131981 - 312 WP_001310011.1 hypothetical protein -
LN359_RS26205 (131978) 131978..132880 - 903 WP_001310012.1 DUF1281 domain-containing protein -
LN359_RS26210 (133299) 133299..134519 - 1221 WP_000343766.1 ISL3 family transposase ISEc53 Transposase
LN359_RS26215 (134538) 134538..135056 - 519 WP_000115885.1 hypothetical protein VF
LN359_RS26220 (135191) 135191..135439 + 249 WP_000619112.1 DinI-like family protein -
LN359_RS26225 (135436) 135436..135873 + 438 WP_000109079.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
LN359_RS26230 (135873) 135873..136894 + 1022 Protein_173 translesion error-prone DNA polymerase V subunit UmuC -
LN359_RS26235 (136996) 136996..138168 + 1173 WP_142438728.1 IS21 family transposase IS21 Transposase
LN359_RS26240 (138168) 138168..138965 + 798 WP_000544830.1 IS21 family transposase IS21 Transposase
LN359_RS26245 (139027) 139027..139278 + 252 Protein_176 DUF4113 domain-containing protein -
LN359_RS26250 (139283) 139283..139675 - 393 WP_000340835.1 plasmid partitioning/stability family protein -
LN359_RS26255 (139680) 139680..140651 - 972 WP_001103694.1 plasmid segregation protein ParM -
LN359_RS26260 (140880) 140880..141524 + 645 WP_000633911.1 AAA family ATPase -
LN359_RS26265 (141518) 141518..141793 + 276 WP_000239529.1 hypothetical protein -
LN359_RS26270 (141931) 141931..142740 - 810 WP_000016979.1 site-specific integrase -
LN359_RS26275 (142741) 142741..143046 - 306 WP_001159871.1 type II toxin-antitoxin system toxin CcdB -
LN359_RS26280 (143048) 143048..143266 - 219 WP_032256270.1 type II toxin-antitoxin system antitoxin CcdA -
LN359_RS26285 (145588) 145588..146229 + 642 WP_000990667.1 hypothetical protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance