MGE detailed information
MGE type: Conjugative plasmid MGE length: 135854 bp
Accession: NZ_CP086621 Location: 1..135854 Organism: Escherichia coli strain RIVM_C039205 Replicon: plasmid pRIVM_C039205_2
Accession: NZ_CP086621 Location: 1..135854 Organism: Escherichia coli strain RIVM_C039205 Replicon: plasmid pRIVM_C039205_2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LN351_RS25390 () | 1..426 | + | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| LN351_RS25395 () | 423..773 | + | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| LN351_RS25400 () | 804..2417 | + | 1614 | WP_135118410.1 | IS66 family transposase ISEc23 | Transposase |
| LN351_RS25405 () | 2449..2769 | + | 321 | Protein_3 | thermonuclease family protein | - |
| LN351_RS25410 () | 2815..3024 | + | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| LN351_RS25415 () | 3062..3652 | + | 591 | WP_000766805.1 | DUF2726 domain-containing protein | - |
| LN351_RS25420 () | 3892..4152 | + | 261 | WP_000083819.1 | replication regulatory protein RepA | - |
| LN351_RS25425 () | 4377..4451 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| LN351_RS25430 () | 4444..5301 | + | 858 | WP_229327591.1 | incFII family plasmid replication initiator RepA | - |
| LN351_RS25435 () | 6240..6893 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| LN351_RS25440 () | 6986..7243 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| LN351_RS25445 () | 7176..7577 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| LN351_RS25450 () | 7826..8241 | + | 416 | Protein_12 | IS1-like element IS1B family transposase | - |
| LN351_RS25455 () | 8277..8822 | - | 546 | Protein_13 | Tn3 family transposase TnpA_Tn3 | Transposase |
| LN351_RS25460 () | 8888..9592 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LN351_RS25465 () | 9657..9836 | + | 180 | Protein_15 | IS1380 family transposase | - |
| LN351_RS25470 () | 10086..10961 | + | 876 | WP_032277257.1 | Beta-lactamase CTX-M-97 | ARG |
| LN351_RS25475 () | 10996..11652 | + | 657 | Protein_17 | IS5 family transposase IS903B | Transposase |
| LN351_RS25480 () | 11717..12421 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LN351_RS25485 () | 12474..12980 | + | 507 | Protein_19 | transposase | - |
| LN351_RS25490 () | 12989..13849 | + | 861 | WP_000493383.1 | EamA family transporter | - |
| LN351_RS25495 () | 13881..15080 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| LN351_RS25500 () | 15186..15812 | + | 627 | WP_031606906.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| LN351_RS25505 () | 15844..16080 | - | 237 | WP_042005022.1 | hypothetical protein | - |
| LN351_RS25510 () | 16134..16970 | - | 837 | WP_000480972.1 | hypothetical protein | ARG |
| LN351_RS25515 () | 16970..17773 | - | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| LN351_RS25520 () | 17834..18649 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| LN351_RS25525 () | 18957..19133 | - | 177 | Protein_27 | replication protein C, IncQ-type | - |
| LN351_RS25530 () | 19194..19898 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LN351_RS25535 () | 20020..20925 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| LN351_RS25540 () | 20922..22160 | + | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| LN351_RS25545 () | 22160..22744 | + | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| LN351_RS25550 () | 23237..24001 | - | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| LN351_RS25555 () | 24119..24184 | - | 66 | Protein_33 | EAL domain-containing protein | - |
| LN351_RS25560 () | 24228..24533 | - | 306 | WP_000130000.1 | hypothetical protein | Relaxase |
| LN351_RS25565 () | 24544..25749 | - | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| LN351_RS25570 () | 25905..26108 | - | 204 | WP_000376616.1 | hypothetical protein | - |
| LN351_RS25575 () | 26236..27075 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| LN351_RS25580 () | 27069..27416 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| LN351_RS25585 () | 27622..28410 | - | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| LN351_RS25590 () | 28541..29014 | - | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| LN351_RS25595 () | 29172..29921 | + | 750 | Protein_41 | IS91 family transposase ISAzo26 | Transposase |
| LN351_RS25600 () | 29980..30684 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LN351_RS25605 () | 30734..30952 | - | 219 | Protein_43 | IS4 family transposase | - |
| LN351_RS25615 () | 31864..31977 | + | 114 | Protein_45 | IS6 family transposase IS15DI | Transposase |
| LN351_RS25620 () | 32115..32285 | + | 171 | Protein_46 | DsbA family protein | - |
| LN351_RS25625 () | 32275..32781 | + | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| LN351_RS25630 () | 32964..33779 | + | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| LN351_RS25635 () | 34126..36012 | + | 1887 | WP_192514405.1 | FTR1 family protein | - |
| LN351_RS25640 () | 36053..36580 | + | 528 | WP_000178050.1 | iron transporter | - |
| LN351_RS25645 () | 36684..38063 | + | 1380 | WP_000119836.1 | Fe-S-containing protein | - |
| LN351_RS25650 () | 38066..39349 | + | 1284 | WP_000964653.1 | ABC transporter permease | - |
| LN351_RS25655 () | 39339..40469 | + | 1131 | WP_000729219.1 | ABC transporter permease | - |
| LN351_RS25660 () | 40474..41169 | + | 696 | WP_063624982.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| LN351_RS25665 () | 41156..41641 | + | 486 | WP_001554949.1 | TlpA disulfide reductase family protein | - |
| LN351_RS25670 () | 41666..42151 | + | 486 | WP_000874189.1 | hypothetical protein | - |
| LN351_RS25675 () | 42273..42905 | + | 633 | Protein_57 | histidine-type phosphatase | - |
| LN351_RS25680 () | 43055..43462 | - | 408 | Protein_58 | IS5 family transposase ISKpn26 | Transposase |
| LN351_RS25685 () | 43527..44231 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LN351_RS25690 () | 44286..44570 | + | 285 | Protein_60 | integrase core domain-containing protein | - |
| LN351_RS25695 () | 44624..45661 | - | 1038 | WP_032248218.1 | LacI family DNA-binding transcriptional regulator | - |
| LN351_RS25705 () | 47533..48600 | + | 1068 | WP_032248209.1 | cellulase family glycosylhydrolase | - |
| LN351_RS25710 () | 48718..50082 | + | 1365 | WP_077758488.1 | MFS transporter | - |
| - () | 50359..50413 | - | 55 | NuclAT_1 | - | - |
| - () | 50359..50413 | - | 55 | NuclAT_1 | - | - |
| - () | 50359..50413 | - | 55 | NuclAT_1 | - | - |
| - () | 50359..50413 | - | 55 | NuclAT_1 | - | - |
| LN351_RS25715 () | 50581..51794 | - | 1214 | Protein_65 | IS3 family transposase | - |
| LN351_RS25720 () | 51849..52064 | + | 216 | Protein_66 | Tn3 family transposase | - |
| LN351_RS25725 () | 52141..52449 | + | 309 | Protein_67 | IS4 family transposase ISEc13 | Transposase |
| LN351_RS25730 () | 52508..53818 | - | 1311 | WP_000476108.1 | ABC transporter substrate-binding protein | - |
| LN351_RS25735 () | 53811..54884 | - | 1074 | WP_000950177.1 | sn-glycerol-3-phosphate import ATP-binding protein UgpC | VF |
| LN351_RS25740 () | 54890..55714 | - | 825 | WP_000922702.1 | phosphodiesterase | - |
| LN351_RS25745 () | 55725..56612 | - | 888 | WP_001271561.1 | carbohydrate ABC transporter permease | - |
| LN351_RS25750 () | 56602..57480 | - | 879 | WP_162753243.1 | sugar ABC transporter permease | - |
| LN351_RS25755 () | 57611..58177 | - | 567 | Protein_73 | zinc-binding dehydrogenase | - |
| LN351_RS25760 () | 58530..59420 | + | 891 | WP_001077068.1 | dihydrodipicolinate synthase family protein | - |
| LN351_RS25765 () | 59445..59825 | + | 381 | WP_000710783.1 | Rid family detoxifying hydrolase | - |
| LN351_RS25770 () | 59858..60823 | + | 966 | WP_001022265.1 | 2-keto-3-deoxygluconate transporter | - |
| LN351_RS25775 () | 60869..61621 | - | 753 | WP_001403368.1 | IclR family transcriptional regulator | - |
| LN351_RS25780 () | 62226..62510 | + | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| LN351_RS25785 () | 62510..62785 | + | 276 | WP_000421273.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| LN351_RS25790 () | 62891..63094 | + | 204 | Protein_80 | hypothetical protein | - |
| LN351_RS25795 () | 63219..63347 | - | 129 | Protein_81 | IS481 family transposase | - |
| LN351_RS25800 () | 63380..64549 | - | 1170 | WP_001403369.1 | hypothetical protein | - |
| LN351_RS25805 () | 65081..65349 | + | 269 | Protein_83 | type II toxin-antitoxin system ParD family antitoxin | - |
| LN351_RS25810 () | 65336..65626 | + | 291 | Protein_84 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| LN351_RS25815 () | 65693..65875 | + | 183 | WP_042344623.1 | hypothetical protein | - |
| LN351_RS25820 () | 65996..66736 | + | 741 | WP_001066941.1 | tyrosine-type recombinase/integrase | - |
| LN351_RS25825 () | 66979..67956 | - | 978 | WP_001309253.1 | RepB family plasmid replication initiator protein | - |
| LN351_RS25830 () | 69131..69772 | - | 642 | WP_000990667.1 | hypothetical protein | - |
| LN351_RS25835 () | 72094..72312 | + | 219 | WP_032256270.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| LN351_RS25840 () | 72314..72619 | + | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| LN351_RS25845 () | 72620..73429 | + | 810 | WP_000016979.1 | site-specific integrase | - |
| LN351_RS25850 () | 73567..73842 | - | 276 | WP_000239529.1 | hypothetical protein | - |
| LN351_RS25855 () | 73836..74480 | - | 645 | WP_000633911.1 | AAA family ATPase | - |
| LN351_RS25860 () | 74709..75680 | + | 972 | WP_001103694.1 | plasmid segregation protein ParM | - |
| LN351_RS25865 () | 75685..76077 | + | 393 | WP_000340835.1 | plasmid partitioning/stability family protein | - |
| LN351_RS25870 () | 76082..76333 | - | 252 | Protein_96 | DUF4113 domain-containing protein | - |
| LN351_RS25875 () | 76395..77192 | - | 798 | WP_000544830.1 | IS21 family transposase IS21 | Transposase |
| LN351_RS25880 () | 77192..78364 | - | 1173 | WP_229321853.1 | IS21 family transposase IS21 | Transposase |
| LN351_RS25885 () | 78466..79487 | - | 1022 | Protein_99 | translesion error-prone DNA polymerase V subunit UmuC | - |
| LN351_RS25890 () | 79487..79924 | - | 438 | WP_000109079.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| LN351_RS25895 () | 79921..80169 | - | 249 | WP_000619112.1 | DinI-like family protein | - |
| LN351_RS25900 () | 80304..80822 | + | 519 | WP_000115885.1 | hypothetical protein | VF |
| LN351_RS25905 () | 80841..82061 | + | 1221 | WP_000343766.1 | ISL3 family transposase ISEc53 | Transposase |
| LN351_RS25910 () | 82480..83382 | + | 903 | WP_122995611.1 | DUF1281 domain-containing protein | - |
| LN351_RS25915 () | 83379..83690 | + | 312 | WP_001310011.1 | hypothetical protein | - |
| LN351_RS25920 () | 83766..84449 | + | 684 | WP_000086169.1 | DNA methylase | - |
| LN351_RS25925 () | 84450..84671 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| LN351_RS25930 () | 84601..85119 | + | 519 | WP_223364201.1 | DUF1380 family protein | - |
| LN351_RS25935 () | 85164..85934 | + | 771 | WP_001004562.1 | hypothetical protein | - |
| LN351_RS25940 () | 86350..86775 | + | 426 | WP_001198903.1 | antirestriction protein | - |
| LN351_RS25945 () | 86822..87244 | + | 423 | WP_000271708.1 | DUF1380 family protein | - |
| LN351_RS25950 () | 87241..87432 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| LN351_RS25955 () | 88395..88625 | + | 231 | WP_000155844.1 | hypothetical protein | - |
| LN351_RS25960 () | 88677..90038 | + | 1362 | WP_000170657.1 | DUF3560 domain-containing protein | - |
| LN351_RS25965 () | 90085..90648 | + | 564 | WP_001311069.1 | class I SAM-dependent methyltransferase | - |
| LN351_RS25970 () | 90648..90878 | + | 231 | WP_001333093.1 | hypothetical protein | - |
| LN351_RS25975 () | 90800..91048 | + | 249 | WP_071606928.1 | hypothetical protein | - |
| LN351_RS25980 () | 91518..92045 | + | 528 | WP_000290793.1 | single-stranded DNA-binding protein | - |
| LN351_RS25985 () | 92101..92334 | + | 234 | WP_000006018.1 | DUF905 domain-containing protein | - |
| LN351_RS25990 () | 92393..94351 | + | 1959 | WP_229327587.1 | ParB/RepB/Spo0J family partition protein | - |
| LN351_RS25995 () | 94406..94840 | + | 435 | WP_000845901.1 | conjugation system SOS inhibitor PsiB | - |
| LN351_RS26000 () | 94837..95599 | + | 763 | Protein_122 | plasmid SOS inhibition protein A | - |
| LN351_RS26005 () | 95568..95756 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - () | 95568..95792 | + | 225 | NuclAT_0 | - | - |
| - () | 95568..95792 | + | 225 | NuclAT_0 | - | - |
| - () | 95568..95792 | + | 225 | NuclAT_0 | - | - |
| - () | 95568..95792 | + | 225 | NuclAT_0 | - | - |
| - | 95725..95790 | - | 66 | - | - | Antitoxin Detail |
| LN351_RS26010 () | 95778..95927 | + | 150 | Protein_124 | plasmid maintenance protein Mok | - |
| LN351_RS26015 () | 95869..95994 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| LN351_RS26020 () | 96214..96444 | + | 231 | WP_071587244.1 | hypothetical protein | - |
| LN351_RS26025 () | 96442..96615 | - | 174 | Protein_127 | hypothetical protein | - |
| LN351_RS26030 () | 96913..97200 | + | 288 | WP_000107537.1 | hypothetical protein | - |
| LN351_RS26035 () | 97321..98142 | + | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| LN351_RS26040 () | 98439..99086 | - | 648 | WP_124760006.1 | hypothetical protein | VF |
| LN351_RS26045 () | 99372..99755 | + | 384 | WP_001151564.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| LN351_RS26050 () | 99949..100635 | + | 687 | WP_000332487.1 | PAS domain-containing protein | - |
| LN351_RS26055 () | 100729..100956 | + | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| LN351_RS26060 () | 100990..101352 | + | 363 | WP_001098998.1 | type IV conjugative transfer system pilin TraA | - |
| LN351_RS26065 () | 101357..101668 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| LN351_RS26070 () | 101690..102256 | + | 567 | WP_000399804.1 | type IV conjugative transfer system protein TraE | - |
| LN351_RS26075 () | 102243..102971 | + | 729 | WP_215200862.1 | type-F conjugative transfer system secretin TraK | - |
| LN351_RS26080 () | 102971..104398 | + | 1428 | WP_000146638.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| LN351_RS26085 () | 104388..104972 | + | 585 | WP_000002795.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| LN351_RS26090 () | 104959..105279 | + | 321 | WP_001057302.1 | conjugal transfer protein TrbD | - |
| LN351_RS26095 () | 105272..105523 | + | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
| LN351_RS26100 () | 105520..106035 | + | 516 | WP_000809893.1 | type IV conjugative transfer system lipoprotein TraV | - |
| LN351_RS26105 () | 106170..106391 | + | 222 | WP_001278978.1 | conjugal transfer protein TraR | - |
| LN351_RS26110 () | 106551..109177 | + | 2627 | Protein_144 | type IV secretion system protein TraC | - |
| LN351_RS26115 () | 109174..109560 | + | 387 | WP_000214082.1 | type-F conjugative transfer system protein TrbI | - |
| LN351_RS26120 () | 109557..110189 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| LN351_RS26125 () | 110186..111178 | + | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| LN351_RS26130 () | 111208..111513 | + | 306 | WP_000224411.1 | hypothetical protein | - |
| LN351_RS26135 () | 111522..112160 | + | 639 | WP_001080257.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| LN351_RS26140 () | 112157..113965 | + | 1809 | WP_024221016.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| LN351_RS26145 () | 113992..114249 | + | 258 | WP_000864320.1 | conjugal transfer protein TrbE | - |
| LN351_RS26150 () | 114242..114985 | + | 744 | WP_001749618.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| LN351_RS26155 () | 115001..115339 | + | 339 | WP_001287905.1 | conjugal transfer protein TrbA | - |
| LN351_RS26160 () | 115466..115750 | + | 285 | WP_001448202.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| LN351_RS26165 () | 115737..116282 | + | 546 | WP_000059824.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| LN351_RS26170 () | 116212..116553 | + | 342 | WP_001448115.1 | P-type conjugative transfer protein TrbJ | - |
| LN351_RS26175 () | 116534..116863 | + | 330 | WP_229327588.1 | F-type conjugal transfer protein TrbF | - |
| LN351_RS26180 () | 116934..117680 | - | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| LN351_RS26185 () | 117695..119236 | - | 1542 | WP_001298859.1 | IS21 family transposase ISEc12 | Transposase |
| LN351_RS26190 () | 119432..119512 | + | 81 | Protein_160 | conjugal transfer protein TrbF | - |
| LN351_RS26195 () | 119499..120872 | + | 1374 | WP_001137364.1 | conjugal transfer pilus assembly protein TraH | - |
| LN351_RS26200 () | 120869..123688 | + | 2820 | WP_229327589.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| LN351_RS26205 () | 123707..124204 | + | 498 | WP_000605861.1 | hypothetical protein | - |
| LN351_RS26210 () | 124236..124967 | + | 732 | WP_024221017.1 | conjugal transfer complement resistance protein TraT | - |
| LN351_RS26215 () | 125220..127418 | + | 2199 | WP_186173458.1 | type IV conjugative transfer system coupling protein TraD | - |
| LN351_RS26220 () | 127418..132688 | + | 5271 | WP_229327590.1 | Multifunctional conjugation protein TraI | Relaxase |
| LN351_RS26225 () | 132708..133454 | + | 747 | WP_000205725.1 | conjugal transfer pilus acetylase TraX | - |
| LN351_RS26230 () | 133513..134373 | + | 861 | WP_000704523.1 | putative protein YcjY | VF |
| LN351_RS26235 () | 134476..135036 | + | 561 | WP_000139321.1 | fertility inhibition protein FinO | - |
| LN351_RS26240 () | 135165..135377 | + | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| LN351_RS26245 () | 135622..135765 | + | 144 | Protein_171 | endonuclease | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|