MGE detailed information

MGE type: Conjugative plasmid        MGE length: 135854 bp
Accession: NZ_CP086621        Location: 1..135854         Organism: Escherichia coli strain RIVM_C039205       Replicon: plasmid pRIVM_C039205_2


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LN351_RS25390 (1) 1..426 + 426 WP_000422741.1 IS66 family transposase ISEc23 Transposase
LN351_RS25395 (423) 423..773 + 351 WP_000624722.1 IS66 family transposase ISEc23 Transposase
LN351_RS25400 (804) 804..2417 + 1614 WP_135118410.1 IS66 family transposase ISEc23 Transposase
LN351_RS25405 (2449) 2449..2769 + 321 Protein_3 thermonuclease family protein -
LN351_RS25410 (2815) 2815..3024 + 210 WP_001298565.1 hemolysin expression modulator Hha -
LN351_RS25415 (3062) 3062..3652 + 591 WP_000766805.1 DUF2726 domain-containing protein -
LN351_RS25420 (3892) 3892..4152 + 261 WP_000083819.1 replication regulatory protein RepA -
LN351_RS25425 (4377) 4377..4451 + 75 WP_001365705.1 RepA leader peptide Tap -
LN351_RS25430 (4444) 4444..5301 + 858 WP_229327591.1 incFII family plasmid replication initiator RepA -
LN351_RS25435 (6240) 6240..6893 + 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
LN351_RS25440 (6986) 6986..7243 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
LN351_RS25445 (7176) 7176..7577 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
LN351_RS25450 (7826) 7826..8241 + 416 Protein_12 IS1-like element IS1B family transposase -
LN351_RS25455 (8277) 8277..8822 - 546 Protein_13 Tn3 family transposase TnpA_Tn3 Transposase
LN351_RS25460 (8888) 8888..9592 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LN351_RS25465 (9657) 9657..9836 + 180 Protein_15 IS1380 family transposase -
LN351_RS25470 (10086) 10086..10961 + 876 WP_032277257.1 Beta-lactamase CTX-M-97 ARG
LN351_RS25475 (10996) 10996..11652 + 657 Protein_17 IS5 family transposase IS903B Transposase
LN351_RS25480 (11717) 11717..12421 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LN351_RS25485 (12474) 12474..12980 + 507 Protein_19 transposase -
LN351_RS25490 (12989) 12989..13849 + 861 WP_000493383.1 EamA family transporter -
LN351_RS25495 (13881) 13881..15080 - 1200 WP_000804064.1 Tetracycline resistance protein, class C ARG
LN351_RS25500 (15186) 15186..15812 + 627 WP_031606906.1 tetracycline resistance transcriptional repressor TetR(A) -
LN351_RS25505 (15844) 15844..16080 - 237 WP_042005022.1 hypothetical protein -
LN351_RS25510 (16134) 16134..16970 - 837 WP_000480972.1 hypothetical protein ARG
LN351_RS25515 (16970) 16970..17773 - 804 WP_001082319.1 Aminoglycoside 3'-phosphotransferase ARG
LN351_RS25520 (17834) 17834..18649 - 816 WP_001043260.1 Dihydropteroate synthase ARG
LN351_RS25525 (18957) 18957..19133 - 177 Protein_27 replication protein C, IncQ-type -
LN351_RS25530 (19194) 19194..19898 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LN351_RS25535 (20020) 20020..20925 + 906 WP_000219391.1 hypothetical protein ARG
LN351_RS25540 (20922) 20922..22160 + 1239 WP_000004159.1 macrolide resistance MFS transporter Mrx(A) -
LN351_RS25545 (22160) 22160..22744 + 585 WP_001137892.1 macrolide-binding transcriptional repressor MphR(A) -
LN351_RS25550 (23237) 23237..24001 - 765 WP_001389365.1 IS6-like element IS6100 family transposase -
LN351_RS25555 (24119) 24119..24184 - 66 Protein_33 EAL domain-containing protein -
LN351_RS25560 (24228) 24228..24533 - 306 WP_000130000.1 hypothetical protein Relaxase
LN351_RS25565 (24544) 24544..25749 - 1206 WP_000184001.1 chromate efflux transporter -
LN351_RS25570 (25905) 25905..26108 - 204 WP_000376616.1 hypothetical protein -
LN351_RS25575 (26236) 26236..27075 - 840 WP_000259031.1 Dihydropteroate synthase ARG
LN351_RS25580 (27069) 27069..27416 - 348 WP_000679427.1 Multidrug transporter EmrE ARG
LN351_RS25585 (27622) 27622..28410 - 789 WP_000503573.1 Streptomycin 3''-adenylyltransferase ARG
LN351_RS25590 (28541) 28541..29014 - 474 WP_001389366.1 trimethoprim-resistant dihydrofolate reductase DfrA17 -
LN351_RS25595 (29172) 29172..29921 + 750 Protein_41 IS91 family transposase ISAzo26 Transposase
LN351_RS25600 (29980) 29980..30684 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LN351_RS25605 (30734) 30734..30952 - 219 Protein_43 IS4 family transposase -
LN351_RS25615 (31864) 31864..31977 + 114 Protein_45 IS6 family transposase IS15DI Transposase
LN351_RS25620 (32115) 32115..32285 + 171 Protein_46 DsbA family protein -
LN351_RS25625 (32275) 32275..32781 + 507 WP_000949452.1 protein disulfide oxidoreductase -
LN351_RS25630 (32964) 32964..33779 + 816 WP_012372823.1 Na(+)-translocating NADH-quinone reductase subunit C -
LN351_RS25635 (34126) 34126..36012 + 1887 WP_192514405.1 FTR1 family protein -
LN351_RS25640 (36053) 36053..36580 + 528 WP_000178050.1 iron transporter -
LN351_RS25645 (36684) 36684..38063 + 1380 WP_000119836.1 Fe-S-containing protein -
LN351_RS25650 (38066) 38066..39349 + 1284 WP_000964653.1 ABC transporter permease -
LN351_RS25655 (39339) 39339..40469 + 1131 WP_000729219.1 ABC transporter permease -
LN351_RS25660 (40474) 40474..41169 + 696 WP_063624982.1 Lipoprotein-releasing system ATP-binding protein LolD VF
LN351_RS25665 (41156) 41156..41641 + 486 WP_001554949.1 TlpA disulfide reductase family protein -
LN351_RS25670 (41666) 41666..42151 + 486 WP_000874189.1 hypothetical protein -
LN351_RS25675 (42273) 42273..42905 + 633 Protein_57 histidine-type phosphatase -
LN351_RS25680 (43055) 43055..43462 - 408 Protein_58 IS5 family transposase ISKpn26 Transposase
LN351_RS25685 (43527) 43527..44231 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LN351_RS25690 (44286) 44286..44570 + 285 Protein_60 integrase core domain-containing protein -
LN351_RS25695 (44624) 44624..45661 - 1038 WP_032248218.1 LacI family DNA-binding transcriptional regulator -
LN351_RS25705 (47533) 47533..48600 + 1068 WP_032248209.1 cellulase family glycosylhydrolase -
LN351_RS25710 (48718) 48718..50082 + 1365 WP_077758488.1 MFS transporter -
- (50359) 50359..50413 - 55 NuclAT_1 - -
- (50359) 50359..50413 - 55 NuclAT_1 - -
- (50359) 50359..50413 - 55 NuclAT_1 - -
- (50359) 50359..50413 - 55 NuclAT_1 - -
LN351_RS25715 (50581) 50581..51794 - 1214 Protein_65 IS3 family transposase -
LN351_RS25720 (51849) 51849..52064 + 216 Protein_66 Tn3 family transposase -
LN351_RS25725 (52141) 52141..52449 + 309 Protein_67 IS4 family transposase ISEc13 Transposase
LN351_RS25730 (52508) 52508..53818 - 1311 WP_000476108.1 ABC transporter substrate-binding protein -
LN351_RS25735 (53811) 53811..54884 - 1074 WP_000950177.1 sn-glycerol-3-phosphate import ATP-binding protein UgpC VF
LN351_RS25740 (54890) 54890..55714 - 825 WP_000922702.1 phosphodiesterase -
LN351_RS25745 (55725) 55725..56612 - 888 WP_001271561.1 carbohydrate ABC transporter permease -
LN351_RS25750 (56602) 56602..57480 - 879 WP_162753243.1 sugar ABC transporter permease -
LN351_RS25755 (57611) 57611..58177 - 567 Protein_73 zinc-binding dehydrogenase -
LN351_RS25760 (58530) 58530..59420 + 891 WP_001077068.1 dihydrodipicolinate synthase family protein -
LN351_RS25765 (59445) 59445..59825 + 381 WP_000710783.1 Rid family detoxifying hydrolase -
LN351_RS25770 (59858) 59858..60823 + 966 WP_001022265.1 2-keto-3-deoxygluconate transporter -
LN351_RS25775 (60869) 60869..61621 - 753 WP_001403368.1 IclR family transcriptional regulator -
LN351_RS25780 (62226) 62226..62510 + 285 WP_001387467.1 ribbon-helix-helix domain-containing protein Antitoxin Detail
LN351_RS25785 (62510) 62510..62785 + 276 WP_000421273.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin Detail
LN351_RS25790 (62891) 62891..63094 + 204 Protein_80 hypothetical protein -
LN351_RS25795 (63219) 63219..63347 - 129 Protein_81 IS481 family transposase -
LN351_RS25800 (63380) 63380..64549 - 1170 WP_001403369.1 hypothetical protein -
LN351_RS25805 (65081) 65081..65349 + 269 Protein_83 type II toxin-antitoxin system ParD family antitoxin -
LN351_RS25810 (65336) 65336..65626 + 291 Protein_84 type II toxin-antitoxin system RelE/ParE family toxin -
LN351_RS25815 (65693) 65693..65875 + 183 WP_042344623.1 hypothetical protein -
LN351_RS25820 (65996) 65996..66736 + 741 WP_001066941.1 tyrosine-type recombinase/integrase -
LN351_RS25825 (66979) 66979..67956 - 978 WP_001309253.1 RepB family plasmid replication initiator protein -
LN351_RS25830 (69131) 69131..69772 - 642 WP_000990667.1 hypothetical protein -
LN351_RS25835 (72094) 72094..72312 + 219 WP_032256270.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin Detail
LN351_RS25840 (72314) 72314..72619 + 306 WP_001159871.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
LN351_RS25845 (72620) 72620..73429 + 810 WP_000016979.1 site-specific integrase -
LN351_RS25850 (73567) 73567..73842 - 276 WP_000239529.1 hypothetical protein -
LN351_RS25855 (73836) 73836..74480 - 645 WP_000633911.1 AAA family ATPase -
LN351_RS25860 (74709) 74709..75680 + 972 WP_001103694.1 plasmid segregation protein ParM -
LN351_RS25865 (75685) 75685..76077 + 393 WP_000340835.1 plasmid partitioning/stability family protein -
LN351_RS25870 (76082) 76082..76333 - 252 Protein_96 DUF4113 domain-containing protein -
LN351_RS25875 (76395) 76395..77192 - 798 WP_000544830.1 IS21 family transposase IS21 Transposase
LN351_RS25880 (77192) 77192..78364 - 1173 WP_229321853.1 IS21 family transposase IS21 Transposase
LN351_RS25885 (78466) 78466..79487 - 1022 Protein_99 translesion error-prone DNA polymerase V subunit UmuC -
LN351_RS25890 (79487) 79487..79924 - 438 WP_000109079.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
LN351_RS25895 (79921) 79921..80169 - 249 WP_000619112.1 DinI-like family protein -
LN351_RS25900 (80304) 80304..80822 + 519 WP_000115885.1 hypothetical protein VF
LN351_RS25905 (80841) 80841..82061 + 1221 WP_000343766.1 ISL3 family transposase ISEc53 Transposase
LN351_RS25910 (82480) 82480..83382 + 903 WP_122995611.1 DUF1281 domain-containing protein -
LN351_RS25915 (83379) 83379..83690 + 312 WP_001310011.1 hypothetical protein -
LN351_RS25920 (83766) 83766..84449 + 684 WP_000086169.1 DNA methylase -
LN351_RS25925 (84450) 84450..84671 + 222 WP_001104873.1 hypothetical protein -
LN351_RS25930 (84601) 84601..85119 + 519 WP_223364201.1 DUF1380 family protein -
LN351_RS25935 (85164) 85164..85934 + 771 WP_001004562.1 hypothetical protein -
LN351_RS25940 (86350) 86350..86775 + 426 WP_001198903.1 antirestriction protein -
LN351_RS25945 (86822) 86822..87244 + 423 WP_000271708.1 DUF1380 family protein -
LN351_RS25950 (87241) 87241..87432 + 192 WP_001027516.1 hypothetical protein -
LN351_RS25955 (88395) 88395..88625 + 231 WP_000155844.1 hypothetical protein -
LN351_RS25960 (88677) 88677..90038 + 1362 WP_000170657.1 DUF3560 domain-containing protein -
LN351_RS25965 (90085) 90085..90648 + 564 WP_001311069.1 class I SAM-dependent methyltransferase -
LN351_RS25970 (90648) 90648..90878 + 231 WP_001333093.1 hypothetical protein -
LN351_RS25975 (90800) 90800..91048 + 249 WP_071606928.1 hypothetical protein -
LN351_RS25980 (91518) 91518..92045 + 528 WP_000290793.1 single-stranded DNA-binding protein -
LN351_RS25985 (92101) 92101..92334 + 234 WP_000006018.1 DUF905 domain-containing protein -
LN351_RS25990 (92393) 92393..94351 + 1959 WP_229327587.1 ParB/RepB/Spo0J family partition protein -
LN351_RS25995 (94406) 94406..94840 + 435 WP_000845901.1 conjugation system SOS inhibitor PsiB -
LN351_RS26000 (94837) 94837..95599 + 763 Protein_122 plasmid SOS inhibition protein A -
LN351_RS26005 (95568) 95568..95756 - 189 WP_001299721.1 hypothetical protein -
- (95568) 95568..95792 + 225 NuclAT_0 - -
- (95568) 95568..95792 + 225 NuclAT_0 - -
- (95568) 95568..95792 + 225 NuclAT_0 - -
- (95568) 95568..95792 + 225 NuclAT_0 - -
LN351_RS26010 (95778) 95778..95927 + 150 Protein_124 plasmid maintenance protein Mok -
LN351_RS26015 (95869) 95869..95994 + 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
LN351_RS26020 (96214) 96214..96444 + 231 WP_071587244.1 hypothetical protein -
LN351_RS26025 (96442) 96442..96615 - 174 Protein_127 hypothetical protein -
LN351_RS26030 (96913) 96913..97200 + 288 WP_000107537.1 hypothetical protein -
LN351_RS26035 (97321) 97321..98142 + 822 WP_001234469.1 DUF932 domain-containing protein -
LN351_RS26040 (98439) 98439..99086 - 648 WP_124760006.1 hypothetical protein VF
LN351_RS26045 (99372) 99372..99755 + 384 WP_001151564.1 conjugal transfer relaxosome DNA-binding protein TraM -
LN351_RS26050 (99949) 99949..100635 + 687 WP_000332487.1 PAS domain-containing protein -
LN351_RS26055 (100729) 100729..100956 + 228 WP_001254388.1 conjugal transfer relaxosome protein TraY -
LN351_RS26060 (100990) 100990..101352 + 363 WP_001098998.1 type IV conjugative transfer system pilin TraA -
LN351_RS26065 (101357) 101357..101668 + 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
LN351_RS26070 (101690) 101690..102256 + 567 WP_000399804.1 type IV conjugative transfer system protein TraE -
LN351_RS26075 (102243) 102243..102971 + 729 WP_215200862.1 type-F conjugative transfer system secretin TraK -
LN351_RS26080 (102971) 102971..104398 + 1428 WP_000146638.1 F-type conjugal transfer pilus assembly protein TraB -
LN351_RS26085 (104388) 104388..104972 + 585 WP_000002795.1 conjugal transfer pilus-stabilizing protein TraP -
LN351_RS26090 (104959) 104959..105279 + 321 WP_001057302.1 conjugal transfer protein TrbD -
LN351_RS26095 (105272) 105272..105523 + 252 WP_001038341.1 conjugal transfer protein TrbG -
LN351_RS26100 (105520) 105520..106035 + 516 WP_000809893.1 type IV conjugative transfer system lipoprotein TraV -
LN351_RS26105 (106170) 106170..106391 + 222 WP_001278978.1 conjugal transfer protein TraR -
LN351_RS26110 (106551) 106551..109177 + 2627 Protein_144 type IV secretion system protein TraC -
LN351_RS26115 (109174) 109174..109560 + 387 WP_000214082.1 type-F conjugative transfer system protein TrbI -
LN351_RS26120 (109557) 109557..110189 + 633 WP_001203720.1 type-F conjugative transfer system protein TraW -
LN351_RS26125 (110186) 110186..111178 + 993 WP_000830838.1 conjugal transfer pilus assembly protein TraU -
LN351_RS26130 (111208) 111208..111513 + 306 WP_000224411.1 hypothetical protein -
LN351_RS26135 (111522) 111522..112160 + 639 WP_001080257.1 type-F conjugative transfer system pilin assembly protein TrbC -
LN351_RS26140 (112157) 112157..113965 + 1809 WP_024221016.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
LN351_RS26145 (113992) 113992..114249 + 258 WP_000864320.1 conjugal transfer protein TrbE -
LN351_RS26150 (114242) 114242..114985 + 744 WP_001749618.1 type-F conjugative transfer system pilin assembly protein TraF -
LN351_RS26155 (115001) 115001..115339 + 339 WP_001287905.1 conjugal transfer protein TrbA -
LN351_RS26160 (115466) 115466..115750 + 285 WP_001448202.1 type-F conjugative transfer system pilin chaperone TraQ -
LN351_RS26165 (115737) 115737..116282 + 546 WP_000059824.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
LN351_RS26170 (116212) 116212..116553 + 342 WP_001448115.1 P-type conjugative transfer protein TrbJ -
LN351_RS26175 (116534) 116534..116863 + 330 WP_229327588.1 F-type conjugal transfer protein TrbF -
LN351_RS26180 (116934) 116934..117680 - 747 WP_001016257.1 IS21 family transposase ISEc12 Transposase
LN351_RS26185 (117695) 117695..119236 - 1542 WP_001298859.1 IS21 family transposase ISEc12 Transposase
LN351_RS26190 (119432) 119432..119512 + 81 Protein_160 conjugal transfer protein TrbF -
LN351_RS26195 (119499) 119499..120872 + 1374 WP_001137364.1 conjugal transfer pilus assembly protein TraH -
LN351_RS26200 (120869) 120869..123688 + 2820 WP_229327589.1 conjugal transfer mating-pair stabilization protein TraG -
LN351_RS26205 (123707) 123707..124204 + 498 WP_000605861.1 hypothetical protein -
LN351_RS26210 (124236) 124236..124967 + 732 WP_024221017.1 conjugal transfer complement resistance protein TraT -
LN351_RS26215 (125220) 125220..127418 + 2199 WP_186173458.1 type IV conjugative transfer system coupling protein TraD -
LN351_RS26220 (127418) 127418..132688 + 5271 WP_229327590.1 Multifunctional conjugation protein TraI Relaxase
LN351_RS26225 (132708) 132708..133454 + 747 WP_000205725.1 conjugal transfer pilus acetylase TraX -
LN351_RS26230 (133513) 133513..134373 + 861 WP_000704523.1 putative protein YcjY VF
LN351_RS26235 (134476) 134476..135036 + 561 WP_000139321.1 fertility inhibition protein FinO -
LN351_RS26240 (135165) 135165..135377 + 213 WP_001309245.1 ANR family transcriptional regulator -
LN351_RS26245 (135622) 135622..135765 + 144 Protein_171 endonuclease -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance