MGE detailed information

MGE type: Conjugative plasmid        MGE length: 138402 bp
Accession: NZ_CP086617        Location: 1..138402         Organism: Escherichia coli strain RIVM_C039629       Replicon: plasmid pRIVM_C039629_1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LN353_RS24870 (1) 1..261 + 261 WP_000083819.1 replication regulatory protein RepA -
LN353_RS24875 (486) 486..560 + 75 WP_001365705.1 RepA leader peptide Tap -
LN353_RS24880 (553) 553..1410 + 858 WP_000130647.1 incFII family plasmid replication initiator RepA -
LN353_RS24885 (2349) 2349..3002 + 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
LN353_RS24890 (3095) 3095..3352 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
LN353_RS24895 (3285) 3285..3686 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
LN353_RS24900 (3935) 3935..4350 + 416 Protein_6 IS1-like element IS1B family transposase -
LN353_RS24905 (4386) 4386..4931 - 546 Protein_7 Tn3 family transposase TnpA_Tn3 Transposase
LN353_RS24910 (4997) 4997..5701 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LN353_RS24915 (5768) 5768..6698 - 931 Protein_9 IS3 family transposase -
LN353_RS24920 (6818) 6818..7738 - 921 Protein_10 IS4 family transposase IS4 Transposase
LN353_RS24925 (7877) 7877..8671 + 795 WP_063625815.1 3-methyl-2-oxobutanoate hydroxymethyltransferase -
LN353_RS24930 (8683) 8683..9534 + 852 WP_032248272.1 pantoate--beta-alanine ligase -
LN353_RS24935 (9679) 9679..9753 - 75 Protein_13 hypothetical protein -
LN353_RS24940 (9832) 9832..10072 + 241 Protein_14 polysaccharide deacetylase family protein -
LN353_RS24945 (10076) 10076..10456 - 381 WP_000621515.1 aspartate 1-decarboxylase -
LN353_RS24950 (10730) 10730..10861 + 132 Protein_16 Rpn family recombination-promoting nuclease/putative transposase -
LN353_RS24955 (11059) 11059..12453 + 1395 WP_050488426.1 MFS transporter -
LN353_RS24960 (12559) 12559..13590 + 1032 WP_000194408.1 LacI family DNA-binding transcriptional regulator -
LN353_RS24965 (13565) 13565..14584 + 1020 WP_077758491.1 nucleoside hydrolase -
LN353_RS24970 (14701) 14701..15405 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LN353_RS24975 (15553) 15553..15657 + 105 Protein_21 integrase core domain-containing protein -
LN353_RS24980 (15807) 15807..16805 + 999 WP_004175650.1 ABC transporter substrate-binding protein -
LN353_RS24985 (16805) 16805..17842 + 1038 WP_032248242.1 Hemin transport system permease protein HmuU VF
LN353_RS24990 (17842) 17842..18603 + 762 WP_000020504.1 Fe(3+) dicitrate transport ATP-binding protein FecE VF
LN353_RS24995 (18660) 18660..19847 + 1188 WP_162753250.1 MFS transporter -
LN353_RS25000 (19943) 19943..20923 + 981 WP_063624983.1 IS5 family transposase ISKpn26 Transposase
LN353_RS25005 (21073) 21073..21705 - 633 Protein_27 histidine-type phosphatase -
LN353_RS25010 (21827) 21827..22312 - 486 WP_000874189.1 hypothetical protein -
LN353_RS25015 (22337) 22337..22822 - 486 WP_001554949.1 TlpA disulfide reductase family protein -
LN353_RS25020 (22809) 22809..23504 - 696 WP_063624982.1 Lipoprotein-releasing system ATP-binding protein LolD VF
LN353_RS25025 (23509) 23509..24237 - 729 Protein_31 FtsX-like permease family protein -
LN353_RS25030 (24292) 24292..24996 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
LN353_RS25035 (25055) 25055..25804 - 750 Protein_33 IS91 family transposase ISAzo26 Transposase
LN353_RS25040 (25962) 25962..26435 + 474 WP_001389366.1 trimethoprim-resistant dihydrofolate reductase DfrA17 -
LN353_RS25045 (26566) 26566..27354 + 789 WP_000503573.1 Streptomycin 3''-adenylyltransferase ARG
LN353_RS25050 (27560) 27560..27907 + 348 WP_000679427.1 Multidrug transporter EmrE ARG
LN353_RS25055 (27901) 27901..28740 + 840 WP_000259031.1 Dihydropteroate synthase ARG
LN353_RS25060 (28868) 28868..29071 + 204 WP_000376616.1 hypothetical protein -
LN353_RS25065 (29227) 29227..30432 + 1206 WP_000184001.1 chromate efflux transporter -
LN353_RS25070 (30443) 30443..30748 + 306 WP_000130000.1 hypothetical protein Relaxase
LN353_RS25075 (30792) 30792..30857 + 66 Protein_41 EAL domain-containing protein -
LN353_RS25080 (30975) 30975..31739 + 765 WP_001389365.1 IS6-like element IS6100 family transposase -
LN353_RS25085 (32232) 32232..32816 - 585 WP_001137892.1 macrolide-binding transcriptional repressor MphR(A) -
LN353_RS25090 (32816) 32816..34054 - 1239 WP_000004159.1 macrolide resistance MFS transporter Mrx(A) -
LN353_RS25095 (34051) 34051..34956 - 906 WP_000219391.1 hypothetical protein ARG
LN353_RS25100 (35078) 35078..35782 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LN353_RS25105 (35843) 35843..36019 + 177 Protein_47 replication protein C, IncQ-type -
LN353_RS25110 (36327) 36327..37142 + 816 WP_001043260.1 Dihydropteroate synthase ARG
LN353_RS25115 (37203) 37203..38006 + 804 WP_001082319.1 Aminoglycoside 3'-phosphotransferase ARG
LN353_RS25120 (38006) 38006..38842 + 837 WP_000480972.1 hypothetical protein ARG
LN353_RS25125 (38896) 38896..39132 + 237 WP_042005022.1 hypothetical protein -
LN353_RS25130 (39164) 39164..39790 - 627 WP_031606906.1 tetracycline resistance transcriptional repressor TetR(A) -
LN353_RS25135 (39896) 39896..41095 + 1200 WP_000804064.1 Tetracycline resistance protein, class C ARG
LN353_RS25140 (41127) 41127..41987 - 861 WP_000493383.1 EamA family transporter -
LN353_RS25145 (41996) 41996..42502 - 507 Protein_55 transposase -
LN353_RS25150 (42555) 42555..43259 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
LN353_RS25155 (43401) 43401..44276 - 876 WP_032277257.1 Beta-lactamase CTX-M-97 ARG
LN353_RS25160 (44526) 44526..44705 - 180 Protein_58 IS1380 family transposase -
LN353_RS25165 (44770) 44770..45474 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LN353_RS25170 (45529) 45529..45813 + 285 Protein_60 integrase core domain-containing protein -
LN353_RS25175 (45867) 45867..46904 - 1038 WP_032248218.1 LacI family DNA-binding transcriptional regulator -
LN353_RS25185 (48776) 48776..49843 + 1068 WP_032248209.1 cellulase family glycosylhydrolase -
LN353_RS25190 (49961) 49961..51325 + 1365 WP_077758488.1 MFS transporter -
- (51602) 51602..51656 - 55 NuclAT_1 - -
- (51602) 51602..51656 - 55 NuclAT_1 - -
- (51602) 51602..51656 - 55 NuclAT_1 - -
- (51602) 51602..51656 - 55 NuclAT_1 - -
LN353_RS25195 (51824) 51824..53037 - 1214 Protein_65 IS3 family transposase -
LN353_RS25200 (53092) 53092..53307 + 216 Protein_66 Tn3 family transposase -
LN353_RS25205 (53384) 53384..53692 + 309 Protein_67 IS4 family transposase ISEc13 Transposase
LN353_RS25210 (53751) 53751..55061 - 1311 WP_000476108.1 ABC transporter substrate-binding protein -
LN353_RS25215 (55054) 55054..56127 - 1074 WP_000950177.1 sn-glycerol-3-phosphate import ATP-binding protein UgpC VF
LN353_RS25220 (56133) 56133..56957 - 825 WP_000922702.1 phosphodiesterase -
LN353_RS25225 (56968) 56968..57855 - 888 WP_001271561.1 carbohydrate ABC transporter permease -
LN353_RS25230 (57845) 57845..58723 - 879 WP_162753243.1 sugar ABC transporter permease -
LN353_RS25235 (58854) 58854..59420 - 567 Protein_73 zinc-binding dehydrogenase -
LN353_RS25240 (59773) 59773..60663 + 891 WP_001077068.1 dihydrodipicolinate synthase family protein -
LN353_RS25245 (60688) 60688..61068 + 381 WP_000710783.1 Rid family detoxifying hydrolase -
LN353_RS25250 (61101) 61101..62066 + 966 WP_001022265.1 2-keto-3-deoxygluconate transporter -
LN353_RS25255 (62112) 62112..62864 - 753 WP_001403368.1 IclR family transcriptional regulator -
LN353_RS25260 (63469) 63469..63753 + 285 WP_001387467.1 ribbon-helix-helix domain-containing protein Antitoxin Detail
LN353_RS25265 (63753) 63753..64028 + 276 WP_000421273.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin Detail
LN353_RS25270 (64134) 64134..64337 + 204 Protein_80 hypothetical protein -
LN353_RS25275 (64462) 64462..64590 - 129 Protein_81 IS481 family transposase -
LN353_RS25280 (64623) 64623..65792 - 1170 WP_001403369.1 hypothetical protein -
LN353_RS25285 (66324) 66324..66592 + 269 Protein_83 type II toxin-antitoxin system ParD family antitoxin -
LN353_RS25290 (66579) 66579..66869 + 291 Protein_84 type II toxin-antitoxin system RelE/ParE family toxin -
LN353_RS25295 (66936) 66936..67118 + 183 WP_042344623.1 hypothetical protein -
LN353_RS25300 (67239) 67239..67979 + 741 WP_001066941.1 tyrosine-type recombinase/integrase -
LN353_RS25305 (68222) 68222..69199 - 978 WP_001309253.1 RepB family plasmid replication initiator protein -
LN353_RS25310 (70374) 70374..71015 - 642 WP_000990667.1 hypothetical protein -
LN353_RS25315 (73337) 73337..73555 + 219 WP_000813634.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin Detail
LN353_RS25320 (73557) 73557..73862 + 306 WP_001159871.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
LN353_RS25325 (73863) 73863..74672 + 810 WP_000016979.1 site-specific integrase -
LN353_RS25330 (74810) 74810..75085 - 276 WP_000239529.1 hypothetical protein -
LN353_RS25335 (75079) 75079..75723 - 645 WP_000633911.1 AAA family ATPase -
LN353_RS25340 (75952) 75952..76923 + 972 WP_001103694.1 plasmid segregation protein ParM -
LN353_RS25345 (76928) 76928..77320 + 393 WP_000340835.1 plasmid partitioning/stability family protein -
LN353_RS25350 (77325) 77325..77576 - 252 Protein_96 DUF4113 domain-containing protein -
LN353_RS25355 (77638) 77638..78435 - 798 WP_000544830.1 IS21 family transposase IS21 Transposase
LN353_RS25360 (78435) 78435..79607 - 1173 WP_000952372.1 IS21 family transposase IS21 Transposase
LN353_RS25365 (79709) 79709..80730 - 1022 Protein_99 translesion error-prone DNA polymerase V subunit UmuC -
LN353_RS25370 (80730) 80730..81167 - 438 WP_000109079.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
LN353_RS25375 (81164) 81164..81412 - 249 WP_000619112.1 DinI-like family protein -
LN353_RS25380 (81547) 81547..82065 + 519 WP_000115885.1 hypothetical protein VF
LN353_RS25385 (82084) 82084..83304 + 1221 WP_000343766.1 ISL3 family transposase ISEc53 Transposase
LN353_RS25390 (83723) 83723..84625 + 903 WP_001310012.1 DUF1281 domain-containing protein -
LN353_RS25395 (84622) 84622..84933 + 312 WP_001310011.1 hypothetical protein -
LN353_RS25400 (85009) 85009..85692 + 684 WP_000086169.1 DNA methylase -
LN353_RS25405 (85693) 85693..85914 + 222 WP_001104873.1 hypothetical protein -
LN353_RS25410 (85844) 85844..86362 + 519 WP_223364201.1 DUF1380 family protein -
LN353_RS25415 (86407) 86407..87177 + 771 WP_001004562.1 hypothetical protein -
LN353_RS25420 (87593) 87593..88018 + 426 WP_001198903.1 antirestriction protein -
LN353_RS25425 (88065) 88065..88487 + 423 WP_000271708.1 DUF1380 family protein -
LN353_RS25430 (88484) 88484..88675 + 192 WP_001027516.1 hypothetical protein -
LN353_RS25435 (89638) 89638..89868 + 231 WP_000155844.1 hypothetical protein -
LN353_RS25440 (89920) 89920..91281 + 1362 WP_000170667.1 DUF3560 domain-containing protein -
LN353_RS25445 (91328) 91328..91891 + 564 WP_001311069.1 class I SAM-dependent methyltransferase -
LN353_RS25450 (91891) 91891..92121 + 231 WP_001333093.1 hypothetical protein -
LN353_RS25455 (92043) 92043..92291 + 249 WP_071606928.1 hypothetical protein -
LN353_RS25460 (92761) 92761..93288 + 528 WP_000290793.1 single-stranded DNA-binding protein -
LN353_RS25465 (93344) 93344..93577 + 234 WP_000006018.1 DUF905 domain-containing protein -
LN353_RS25470 (93636) 93636..95594 + 1959 WP_032152921.1 ParB/RepB/Spo0J family partition protein -
LN353_RS25475 (95649) 95649..96083 + 435 WP_000845901.1 conjugation system SOS inhibitor PsiB -
LN353_RS25480 (96080) 96080..96842 + 763 Protein_122 plasmid SOS inhibition protein A -
LN353_RS25485 (96811) 96811..96999 - 189 WP_001299721.1 hypothetical protein -
- (96811) 96811..97035 + 225 NuclAT_0 - -
- (96811) 96811..97035 + 225 NuclAT_0 - -
- (96811) 96811..97035 + 225 NuclAT_0 - -
- (96811) 96811..97035 + 225 NuclAT_0 - -
LN353_RS25490 (97021) 97021..97170 + 150 Protein_124 plasmid maintenance protein Mok -
LN353_RS25495 (97112) 97112..97237 + 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
LN353_RS25500 (97457) 97457..97687 + 231 WP_071587244.1 hypothetical protein -
LN353_RS25505 (97685) 97685..97858 - 174 Protein_127 hypothetical protein -
LN353_RS25510 (98156) 98156..98443 + 288 WP_000107537.1 hypothetical protein -
LN353_RS25515 (98564) 98564..99385 + 822 WP_001234469.1 DUF932 domain-containing protein -
LN353_RS25520 (99682) 99682..100329 - 648 WP_124760006.1 hypothetical protein VF
LN353_RS25525 (100615) 100615..100998 + 384 WP_001151564.1 conjugal transfer relaxosome DNA-binding protein TraM -
LN353_RS25530 (101192) 101192..101878 + 687 WP_000332487.1 PAS domain-containing protein -
LN353_RS25535 (101972) 101972..102199 + 228 WP_001254388.1 conjugal transfer relaxosome protein TraY -
LN353_RS25540 (102233) 102233..102595 + 363 WP_001098998.1 type IV conjugative transfer system pilin TraA -
LN353_RS25545 (102600) 102600..102911 + 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
LN353_RS25550 (102933) 102933..103499 + 567 WP_000399804.1 type IV conjugative transfer system protein TraE -
LN353_RS25555 (103486) 103486..104214 + 729 WP_001230787.1 type-F conjugative transfer system secretin TraK -
LN353_RS25560 (104214) 104214..105641 + 1428 WP_000146638.1 F-type conjugal transfer pilus assembly protein TraB -
LN353_RS25565 (105631) 105631..106215 + 585 WP_000002795.1 conjugal transfer pilus-stabilizing protein TraP -
LN353_RS25570 (106202) 106202..106522 + 321 WP_001057302.1 conjugal transfer protein TrbD -
LN353_RS25575 (106515) 106515..106766 + 252 WP_001038341.1 conjugal transfer protein TrbG -
LN353_RS25580 (106763) 106763..107278 + 516 WP_000809893.1 type IV conjugative transfer system lipoprotein TraV -
LN353_RS25585 (107413) 107413..107634 + 222 WP_001278978.1 conjugal transfer protein TraR -
LN353_RS25590 (107794) 107794..110420 + 2627 Protein_144 type IV secretion system protein TraC -
LN353_RS25595 (110417) 110417..110803 + 387 WP_000214082.1 type-F conjugative transfer system protein TrbI -
LN353_RS25600 (110800) 110800..111432 + 633 WP_001203720.1 type-F conjugative transfer system protein TraW -
LN353_RS25605 (111429) 111429..112421 + 993 WP_000830838.1 conjugal transfer pilus assembly protein TraU -
LN353_RS25610 (112451) 112451..112756 + 306 WP_000224411.1 hypothetical protein -
LN353_RS25615 (112765) 112765..113403 + 639 WP_001080257.1 type-F conjugative transfer system pilin assembly protein TrbC -
LN353_RS25620 (113400) 113400..115208 + 1809 WP_024221016.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
LN353_RS25625 (115235) 115235..115492 + 258 WP_000864320.1 conjugal transfer protein TrbE -
LN353_RS25630 (115485) 115485..116228 + 744 WP_001749618.1 type-F conjugative transfer system pilin assembly protein TraF -
LN353_RS25635 (116244) 116244..116582 + 339 WP_001287905.1 conjugal transfer protein TrbA -
LN353_RS25640 (116709) 116709..116993 + 285 WP_001448202.1 type-F conjugative transfer system pilin chaperone TraQ -
LN353_RS25645 (116980) 116980..117525 + 546 WP_000059824.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
LN353_RS25650 (117455) 117455..117796 + 342 WP_001448115.1 P-type conjugative transfer protein TrbJ -
LN353_RS25655 (117777) 117777..118169 + 393 WP_000660703.1 F-type conjugal transfer protein TrbF -
LN353_RS25660 (118156) 118156..119529 + 1374 WP_001137364.1 conjugal transfer pilus assembly protein TraH -
LN353_RS25665 (119526) 119526..122345 + 2820 WP_001007057.1 conjugal transfer mating-pair stabilization protein TraG -
LN353_RS25670 (122364) 122364..122861 + 498 WP_000605861.1 hypothetical protein -
LN353_RS25675 (122893) 122893..123624 + 732 WP_024221017.1 conjugal transfer complement resistance protein TraT -
LN353_RS25680 (123877) 123877..126075 + 2199 WP_032302075.1 type IV conjugative transfer system coupling protein TraD -
LN353_RS25685 (126075) 126075..131345 + 5271 WP_048967012.1 Multifunctional conjugation protein TraI Relaxase
LN353_RS25690 (131365) 131365..132111 + 747 WP_000205725.1 conjugal transfer pilus acetylase TraX -
LN353_RS25695 (132170) 132170..133030 + 861 WP_000704523.1 putative protein YcjY VF
LN353_RS25700 (133133) 133133..133693 + 561 WP_000139321.1 fertility inhibition protein FinO -
LN353_RS25705 (133822) 133822..134034 + 213 WP_001309245.1 ANR family transcriptional regulator -
LN353_RS25710 (134279) 134279..134422 + 144 Protein_168 endonuclease -
LN353_RS25715 (134512) 134512..134937 + 426 WP_000422741.1 IS66 family transposase ISEc23 Transposase
LN353_RS25720 (134934) 134934..135284 + 351 WP_000624722.1 IS66 family transposase ISEc23 Transposase
LN353_RS25725 (135315) 135315..136928 + 1614 WP_135118410.1 IS66 family transposase ISEc23 Transposase
LN353_RS25730 (136960) 136960..137280 + 321 Protein_172 thermonuclease family protein -
LN353_RS25735 (137326) 137326..137535 + 210 WP_001298565.1 hemolysin expression modulator Hha -
LN353_RS25740 (137573) 137573..138163 + 591 WP_000766805.1 DUF2726 domain-containing protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance