MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 102745 bp
Accession: NZ_CP084211 Location: 1..102745 Organism: Escherichia coli strain EC2648-R2 Replicon: plasmid pKP2648-KPCR
Accession: NZ_CP084211 Location: 1..102745 Organism: Escherichia coli strain EC2648-R2 Replicon: plasmid pKP2648-KPCR
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LDB16_RS22600 (1) | 1..858 | + | 858 | WP_032495102.1 | incFII family plasmid replication initiator RepA | - |
| LDB16_RS22605 (1797) | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| LDB16_RS22610 (2543) | 2543..2800 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| LDB16_RS22615 (2733) | 2733..3134 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| LDB16_RS22620 (3383) | 3383..3798 | + | 416 | Protein_4 | IS1-like element IS1B family transposase | - |
| LDB16_RS22625 (3834) | 3834..4379 | - | 546 | Protein_5 | Tn3 family transposase TnpA_Tn3 | Transposase |
| LDB16_RS22630 (4445) | 4445..5149 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LDB16_RS22635 (5219) | 5219..5410 | + | 192 | Protein_7 | IS1380 family transposase | - |
| LDB16_RS22640 (5660) | 5660..6535 | + | 876 | WP_013188475.1 | Beta-lactamase Toho-1 | ARG |
| LDB16_RS22645 (6570) | 6570..7538 | + | 969 | WP_013362812.1 | IS5 family transposase IS903B | Transposase |
| LDB16_RS22650 (7818) | 7818..8522 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LDB16_RS22655 (8575) | 8575..9816 | + | 1242 | Protein_11 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| LDB16_RS22660 (9843) | 9843..10100 | + | 258 | WP_053913405.1 | conjugal transfer protein TrbE | - |
| LDB16_RS22665 (10093) | 10093..10836 | + | 744 | WP_015059017.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| LDB16_RS22670 (10997) | 10997..11233 | + | 237 | WP_000270010.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| LDB16_RS22675 (11220) | 11220..11765 | + | 546 | WP_000059817.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| LDB16_RS22680 (11755) | 11755..12069 | + | 315 | WP_001384255.1 | P-type conjugative transfer protein TrbJ | - |
| LDB16_RS22685 (12023) | 12023..12415 | + | 393 | WP_000126338.1 | F-type conjugal transfer protein TrbF | - |
| LDB16_RS22690 (12402) | 12402..13775 | + | 1374 | WP_000944325.1 | conjugal transfer pilus assembly protein TraH | - |
| LDB16_RS22695 (13772) | 13772..16588 | + | 2817 | WP_015059018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| LDB16_RS22700 (16621) | 16621..17142 | + | 522 | WP_000632668.1 | conjugal transfer entry exclusion protein TraS | - |
| LDB16_RS22705 (17167) | 17167..17898 | + | 732 | WP_021559024.1 | conjugal transfer complement resistance protein TraT | - |
| LDB16_RS22710 (18101) | 18101..18838 | + | 738 | WP_015059020.1 | hypothetical protein | - |
| LDB16_RS22715 (18889) | 18889..21105 | + | 2217 | WP_059274178.1 | type IV conjugative transfer system coupling protein TraD | - |
| LDB16_RS22720 (21105) | 21105..26240 | + | 5136 | WP_071177725.1 | Multifunctional conjugation protein TraI | Relaxase |
| LDB16_RS22725 (26274) | 26274..26978 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LDB16_RS22730 (27041) | 27041..27301 | + | 261 | Protein_26 | chemotaxis protein | - |
| LDB16_RS22735 (27365) | 27365..28069 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LDB16_RS22740 (28123) | 28123..28446 | - | 324 | Protein_28 | class II aldolase/adducin family protein | - |
| LDB16_RS22745 (28439) | 28439..29691 | - | 1253 | Protein_29 | four-carbon acid sugar kinase family protein | - |
| LDB16_RS22750 (29703) | 29703..30605 | - | 903 | WP_002903955.1 | NAD(P)-dependent oxidoreductase | - |
| LDB16_RS22755 (30866) | 30866..31627 | + | 762 | WP_002210513.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| LDB16_RS22760 (31648) | 31648..32508 | - | 861 | WP_004176269.1 | Beta-lactamase SHV-1 | ARG |
| LDB16_RS22765 (32645) | 32645..32713 | + | 69 | Protein_33 | IS6 family transposase | - |
| LDB16_RS22770 (32749) | 32749..35715 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| LDB16_RS22775 (35719) | 35719..36279 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| LDB16_RS22780 (36671) | 36671..37288 | + | 618 | Protein_36 | replication protein | - |
| LDB16_RS22785 (37822) | 37822..38100 | + | 279 | WP_013213990.1 | hypothetical protein | - |
| LDB16_RS22790 (38211) | 38211..38636 | + | 426 | WP_013213989.1 | antirestriction protein | - |
| LDB16_RS22795 (38764) | 38764..38919 | + | 156 | WP_013213988.1 | hypothetical protein | - |
| LDB16_RS22800 (38965) | 38965..39261 | + | 297 | WP_013213987.1 | transcriptional regulator | - |
| LDB16_RS22805 (39365) | 39365..40246 | + | 882 | Protein_41 | IS1182 family transposase ISKpn6 | Transposase |
| LDB16_RS22810 (40496) | 40496..41377 | - | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| LDB16_RS22815 (41653) | 41653..42633 | - | 981 | WP_013213985.1 | IS481 family transposase ISKpn27 | Transposase |
| LDB16_RS22820 (42756) | 42756..43217 | - | 462 | Protein_44 | Tn3 family transposase TnpR_Tn3 | Transposase |
| LDB16_RS22825 (43269) | 43269..43973 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LDB16_RS22830 (44038) | 44038..45210 | - | 1173 | Protein_46 | transposase | - |
| LDB16_RS22835 (45285) | 45285..45953 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| LDB16_RS22840 (45989) | 45989..46225 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| LDB16_RS22845 (46222) | 46222..46584 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| LDB16_RS22850 (46602) | 46602..48296 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| LDB16_RS22855 (48348) | 48348..48770 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| LDB16_RS22860 (48806) | 48806..49081 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| LDB16_RS22865 (49095) | 49095..49445 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| LDB16_RS22870 (49517) | 49517..49951 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| LDB16_RS22875 (50030) | 50030..51034 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| LDB16_RS22880 (51314) | 51314..51586 | - | 273 | Protein_56 | IS5 family transposase ISPan1 | Transposase |
| LDB16_RS22890 (52568) | 52568..53590 | - | 1023 | WP_000361404.1 | helicase UvrD | - |
| LDB16_RS22895 (53575) | 53575..55137 | - | 1563 | WP_004206609.1 | AAA family ATPase | - |
| LDB16_RS22900 (55211) | 55211..55627 | - | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| LDB16_RS22905 (55624) | 55624..55854 | - | 231 | WP_001261282.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| LDB16_RS22910 (55811) | 55811..56272 | + | 462 | WP_014343465.1 | hypothetical protein | - |
| LDB16_RS22915 (56433) | 56433..57377 | + | 945 | WP_011977810.1 | hypothetical protein | - |
| LDB16_RS22920 (57414) | 57414..57806 | + | 393 | WP_011977811.1 | hypothetical protein | - |
| LDB16_RS22925 (57864) | 57864..58385 | + | 522 | WP_013214008.1 | hypothetical protein | - |
| LDB16_RS22930 (58431) | 58431..58634 | + | 204 | WP_011977813.1 | hypothetical protein | - |
| LDB16_RS22935 (58664) | 58664..59668 | + | 1005 | WP_011977814.1 | hypothetical protein | - |
| LDB16_RS22940 (59852) | 59852..60631 | + | 780 | WP_013214009.1 | site-specific integrase | - |
| LDB16_RS22945 (60677) | 60677..60934 | - | 258 | WP_013214010.1 | hypothetical protein | - |
| LDB16_RS22950 (61063) | 61063..61176 | - | 114 | WP_014343462.1 | hypothetical protein | - |
| LDB16_RS22955 (61712) | 61712..62578 | + | 867 | WP_004118283.1 | replication initiation protein | - |
| LDB16_RS22960 (63688) | 63688..64893 | + | 1206 | WP_011977818.1 | AAA family ATPase | - |
| LDB16_RS22965 (64893) | 64893..65867 | + | 975 | WP_011977819.1 | ParB family protein | - |
| LDB16_RS22970 (65949) | 65949..67220 | - | 1272 | WP_013214011.1 | Y-family DNA polymerase | - |
| LDB16_RS22975 (67220) | 67220..67651 | - | 432 | WP_001568036.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| LDB16_RS22980 (68058) | 68058..69545 | + | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| LDB16_RS22985 (69794) | 69794..70765 | + | 972 | WP_004152353.1 | plasmid segregation protein ParM | - |
| LDB16_RS22990 (70768) | 70768..71439 | + | 672 | WP_013214012.1 | plasmid partitioning/stability family protein | - |
| LDB16_RS22995 (71502) | 71502..71732 | + | 231 | WP_001568040.1 | hypothetical protein | - |
| LDB16_RS23000 (71928) | 71928..72097 | + | 170 | Protein_80 | hypothetical protein | - |
| LDB16_RS23005 (72169) | 72169..72870 | + | 702 | WP_001568041.1 | DNA methylase | - |
| LDB16_RS23010 (72870) | 72870..73091 | + | 222 | WP_001568042.1 | hypothetical protein | - |
| LDB16_RS23015 (73101) | 73101..73520 | + | 420 | WP_001568043.1 | DUF1380 domain-containing protein | - |
| LDB16_RS23020 (73574) | 73574..74341 | + | 768 | WP_013214013.1 | hypothetical protein | - |
| LDB16_RS23025 (75022) | 75022..75450 | + | 429 | WP_001568045.1 | antirestriction protein | - |
| LDB16_RS23030 (75493) | 75493..75999 | + | 507 | WP_013214014.1 | antirestriction protein ArdA | - |
| LDB16_RS23035 (76042) | 76042..76233 | + | 192 | WP_001568047.1 | hypothetical protein | - |
| LDB16_RS23040 (76421) | 76421..76675 | + | 255 | WP_011977779.1 | DNA polymerase III subunit theta | - |
| LDB16_RS23045 (76710) | 76710..77030 | + | 321 | WP_001568049.1 | hypothetical protein | - |
| LDB16_RS23050 (77710) | 77710..77937 | + | 228 | WP_001568050.1 | hypothetical protein | - |
| LDB16_RS23055 (78029) | 78029..78259 | + | 231 | WP_001568051.1 | hypothetical protein | - |
| LDB16_RS23060 (78311) | 78311..79666 | + | 1356 | WP_014343515.1 | DUF3560 domain-containing protein | - |
| LDB16_RS23065 (79714) | 79714..80277 | + | 564 | WP_014343514.1 | methyltransferase | - |
| LDB16_RS23070 (81110) | 81110..81652 | + | 543 | WP_014343512.1 | single-stranded DNA-binding protein | - |
| LDB16_RS23075 (81701) | 81701..81949 | + | 249 | WP_001568055.1 | DUF905 domain-containing protein | - |
| LDB16_RS23080 (82019) | 82019..84076 | + | 2058 | WP_015493064.1 | ParB/RepB/Spo0J family partition protein | - |
| LDB16_RS23085 (84121) | 84121..84552 | + | 432 | WP_001568057.1 | conjugation system SOS inhibitor PsiB | - |
| LDB16_RS23090 (84549) | 84549..85277 | + | 729 | WP_001568058.1 | plasmid SOS inhibition protein A | - |
| LDB16_RS23095 (85274) | 85274..85600 | + | 327 | WP_013023807.1 | hypothetical protein | - |
| LDB16_RS23100 (85656) | 85656..86030 | + | 375 | WP_014343510.1 | hypothetical protein | - |
| LDB16_RS23105 (86214) | 86214..87287 | - | 1074 | WP_013609528.1 | IS481 family transposase ISKpn28 | Transposase |
| LDB16_RS23110 (87398) | 87398..87517 | + | 120 | WP_159376494.1 | type I toxin-antitoxin system Hok family toxin | - |
| LDB16_RS23115 (88210) | 88210..88482 | + | 273 | WP_040245921.1 | hypothetical protein | - |
| LDB16_RS23120 (88479) | 88479..88829 | + | 351 | WP_040245917.1 | hypothetical protein | - |
| LDB16_RS23125 (88844) | 88844..89161 | + | 318 | WP_014343505.1 | hypothetical protein | - |
| LDB16_RS23130 (90002) | 90002..90358 | + | 357 | WP_014343501.1 | hypothetical protein | - |
| LDB16_RS23135 (90419) | 90419..90631 | + | 213 | WP_014343500.1 | hypothetical protein | - |
| LDB16_RS23140 (90642) | 90642..90866 | + | 225 | WP_014343499.1 | hypothetical protein | - |
| LDB16_RS23145 (90947) | 90947..91267 | + | 321 | WP_014343498.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| LDB16_RS23150 (91257) | 91257..91535 | + | 279 | WP_004152721.1 | helix-turn-helix transcriptional regulator | - |
| LDB16_RS23155 (91539) | 91539..91643 | + | 105 | Protein_111 | transcriptional regulator | - |
| LDB16_RS23160 (92472) | 92472..93293 | + | 822 | WP_004152492.1 | DUF932 domain-containing protein | - |
| LDB16_RS23165 (93326) | 93326..93655 | + | 330 | WP_013214015.1 | DUF5983 family protein | - |
| LDB16_RS23170 (93688) | 93688..94173 | - | 486 | WP_014343495.1 | hypothetical protein | VF |
| LDB16_RS23175 (94564) | 94564..94980 | + | 417 | WP_014343494.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| LDB16_RS23180 (95180) | 95180..95917 | + | 738 | WP_154244330.1 | conjugal transfer protein TrbJ | - |
| LDB16_RS23185 (96032) | 96032..96238 | + | 207 | WP_171773970.1 | TraY domain-containing protein | - |
| LDB16_RS23190 (96300) | 96300..96668 | + | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| LDB16_RS23195 (96682) | 96682..96987 | + | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| LDB16_RS23200 (97007) | 97007..97372 | + | 366 | Protein_120 | type IV conjugative transfer system protein TraE | - |
| LDB16_RS23205 (97427) | 97427..98131 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LDB16_RS23210 (98156) | 98156..98356 | + | 201 | WP_072354025.1 | hypothetical protein | - |
| LDB16_RS23215 (98376) | 98376..99122 | + | 747 | WP_000205770.1 | conjugal transfer pilus acetylase TraX | - |
| LDB16_RS23220 (99177) | 99177..99737 | + | 561 | WP_000139328.1 | fertility inhibition protein FinO | - |
| LDB16_RS23225 (99869) | 99869..100069 | + | 201 | WP_015059022.1 | hypothetical protein | - |
| LDB16_RS23230 (100455) | 100455..101054 | + | 600 | WP_032083981.1 | PIN domain-containing protein | - |
| - (101649) | 101649..101708 | - | 60 | NuclAT_0 | - | Antitoxin Detail |
| - (101649) | 101649..101708 | - | 60 | NuclAT_0 | - | Antitoxin Detail |
| - (101649) | 101649..101708 | - | 60 | NuclAT_0 | - | Antitoxin Detail |
| - (101649) | 101649..101708 | - | 60 | NuclAT_0 | - | Antitoxin Detail |
| LDB16_RS23235 (101753) | 101753..101902 | + | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| LDB16_RS23240 (102186) | 102186..102434 | + | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|