NZ_CP0842081..139530

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 139530 bp
Accession: NZ_CP084208        Location: 1..139530         Organism: Escherichia coli strain EC2648-R1-1       Replicon: plasmid pKPC-fusion-1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDB15_RS22330 (3) 3..251 + 249 WP_001568055.1 DUF905 domain-containing protein -
LDB15_RS22335 (321) 321..2378 + 2058 WP_015493064.1 ParB/RepB/Spo0J family partition protein -
LDB15_RS22340 (2423) 2423..2854 + 432 WP_001568057.1 conjugation system SOS inhibitor PsiB -
LDB15_RS22345 (2851) 2851..3579 + 729 WP_001568058.1 plasmid SOS inhibition protein A -
LDB15_RS22350 (3576) 3576..3902 + 327 WP_013023807.1 hypothetical protein -
LDB15_RS22355 (3958) 3958..4332 + 375 WP_014343510.1 hypothetical protein -
LDB15_RS22360 (4516) 4516..5589 - 1074 WP_013609528.1 IS481 family transposase ISKpn28 Transposase
LDB15_RS22365 (5700) 5700..5819 + 120 WP_159376494.1 type I toxin-antitoxin system Hok family toxin -
LDB15_RS22370 (6512) 6512..6784 + 273 WP_040245921.1 hypothetical protein -
LDB15_RS22375 (6781) 6781..7131 + 351 WP_040245917.1 hypothetical protein -
LDB15_RS22380 (7146) 7146..7463 + 318 WP_014343505.1 hypothetical protein -
LDB15_RS22385 (8304) 8304..8660 + 357 WP_014343501.1 hypothetical protein -
LDB15_RS22390 (8721) 8721..8933 + 213 WP_014343500.1 hypothetical protein -
LDB15_RS22395 (8944) 8944..9168 + 225 WP_014343499.1 hypothetical protein -
LDB15_RS22400 (9249) 9249..9569 + 321 WP_014343498.1 type II toxin-antitoxin system RelE/ParE family toxin -
LDB15_RS22405 (9559) 9559..9837 + 279 WP_004152721.1 helix-turn-helix transcriptional regulator -
LDB15_RS22410 (9841) 9841..9945 + 105 Protein_16 transcriptional regulator -
LDB15_RS22415 (10774) 10774..11595 + 822 WP_004152492.1 DUF932 domain-containing protein -
LDB15_RS22420 (11628) 11628..11957 + 330 WP_013214015.1 DUF5983 family protein -
LDB15_RS22425 (11990) 11990..12475 - 486 WP_014343495.1 hypothetical protein VF
LDB15_RS22430 (12866) 12866..13282 + 417 WP_014343494.1 conjugal transfer relaxosome DNA-binding protein TraM -
LDB15_RS22435 (13482) 13482..14219 + 738 WP_154244330.1 conjugal transfer protein TrbJ -
LDB15_RS22440 (14334) 14334..14540 + 207 WP_171773970.1 TraY domain-containing protein -
LDB15_RS22445 (14602) 14602..14970 + 369 WP_004194426.1 type IV conjugative transfer system pilin TraA -
LDB15_RS22450 (14984) 14984..15289 + 306 WP_004144424.1 type IV conjugative transfer system protein TraL -
LDB15_RS22455 (15309) 15309..15674 + 366 Protein_25 type IV conjugative transfer system protein TraE -
LDB15_RS22460 (15729) 15729..16433 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LDB15_RS22465 (16458) 16458..16658 + 201 WP_072354025.1 hypothetical protein -
LDB15_RS22470 (16678) 16678..17424 + 747 WP_000205770.1 conjugal transfer pilus acetylase TraX -
LDB15_RS22475 (17479) 17479..18039 + 561 WP_000139328.1 fertility inhibition protein FinO -
LDB15_RS22480 (18171) 18171..18371 + 201 WP_015059022.1 hypothetical protein -
LDB15_RS22485 (18757) 18757..19356 + 600 WP_032083981.1 PIN domain-containing protein -
- (19951) 19951..20010 - 60 NuclAT_0 - Antitoxin Detail
- (19951) 19951..20010 - 60 NuclAT_0 - Antitoxin Detail
- (19951) 19951..20010 - 60 NuclAT_0 - Antitoxin Detail
- (19951) 19951..20010 - 60 NuclAT_0 - Antitoxin Detail
LDB15_RS22490 (20055) 20055..20204 + 150 WP_001312851.1 Hok/Gef family protein Toxin Detail
LDB15_RS22495 (20488) 20488..20736 + 249 WP_000083837.1 replication regulatory protein RepA -
LDB15_RS23395 (20981) 20981..21055 + 75 WP_001375168.1 RepA leader peptide Tap -
LDB15_RS22505 (21048) 21048..21905 + 858 WP_032495102.1 incFII family plasmid replication initiator RepA -
LDB15_RS22510 (22844) 22844..23497 + 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
LDB15_RS22515 (23590) 23590..23847 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
LDB15_RS22520 (23780) 23780..24181 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
LDB15_RS22525 (24430) 24430..24845 + 416 Protein_39 IS1-like element IS1B family transposase -
LDB15_RS22530 (24881) 24881..25426 - 546 Protein_40 Tn3 family transposase TnpA_Tn3 Transposase
LDB15_RS22535 (25492) 25492..26196 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LDB15_RS22540 (26266) 26266..26457 + 192 Protein_42 IS1380 family transposase -
LDB15_RS22545 (26707) 26707..27582 + 876 WP_013188475.1 Beta-lactamase Toho-1 ARG
LDB15_RS22550 (27617) 27617..28585 + 969 WP_013362812.1 IS5 family transposase IS903B Transposase
LDB15_RS22555 (28865) 28865..29569 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LDB15_RS22560 (29575) 29575..29997 + 423 WP_250690638.1 Type IV secretion system protein virB5 VF
LDB15_RS22565 (30001) 30001..30237 + 237 WP_000733633.1 EexN family lipoprotein -
LDB15_RS22570 (30316) 30316..31299 + 984 WP_158212833.1 type IV secretion system protein -
LDB15_RS22575 (31394) 31394..31564 + 171 WP_021536809.1 hypothetical protein -
LDB15_RS22580 (31567) 31567..32283 + 717 WP_000914645.1 Type IV secretion system protein virB8 VF
LDB15_RS22585 (32286) 32286..33173 + 888 WP_000744355.1 Type IV secretion system protein virB9 VF
LDB15_RS22590 (33170) 33170..34324 + 1155 WP_001224296.1 Protein virB10 VF
LDB15_RS22595 (34317) 34317..35348 + 1032 WP_000138004.1 Type IV secretion system protein VirB11 VF
LDB15_RS22600 (35311) 35311..35865 + 555 WP_000616063.1 Phospholipase D VF
LDB15_RS22605 (35878) 35878..36360 + 483 WP_036896345.1 GNAT family protein -
LDB15_RS22610 (36372) 36372..36566 + 195 WP_000529710.1 hypothetical protein -
LDB15_RS22615 (36844) 36844..39753 - 2910 WP_000932317.1 Multifunctional conjugation protein TraI Relaxase
LDB15_RS22620 (39756) 39756..41333 - 1578 WP_001001035.1 type IV secretion system DNA-binding domain-containing protein -
LDB15_RS22625 (41326) 41326..41673 - 348 WP_001139329.1 hypothetical protein -
LDB15_RS22630 (42105) 42105..42548 + 444 WP_024249956.1 hypothetical protein -
LDB15_RS22635 (42561) 42561..43271 + 711 WP_000686338.1 StbB family protein -
LDB15_RS22640 (43273) 43273..43641 + 369 WP_000414914.1 plasmid stabilization protein StbC -
LDB15_RS22645 (43855) 43855..44625 + 771 WP_000586559.1 SprT-like domain-containing protein -
LDB15_RS22650 (44665) 44665..44853 - 189 WP_001001010.1 hypothetical protein -
LDB15_RS22655 (44858) 44858..45115 - 258 WP_021536820.1 hypothetical protein -
LDB15_RS22660 (45188) 45188..45343 - 156 WP_021536821.1 hypothetical protein -
LDB15_RS22665 (45496) 45496..45738 - 243 WP_060628106.1 hypothetical protein -
LDB15_RS22670 (45793) 45793..46080 - 288 WP_001098466.1 hypothetical protein -
LDB15_RS22675 (46432) 46432..46572 - 141 WP_153302164.1 hypothetical protein -
LDB15_RS22680 (47515) 47515..48627 + 1113 WP_001300563.1 IS4 family transposase IS421 Transposase
LDB15_RS22685 (48818) 48818..49240 - 423 WP_021536823.1 hypothetical protein -
LDB15_RS22690 (49948) 49948..50250 - 303 WP_000257688.1 TrfB-related DNA-binding protein -
LDB15_RS22695 (50318) 50318..50797 - 480 WP_060628166.1 single-stranded DNA-binding protein -
LDB15_RS22700 (50855) 50855..51682 - 828 WP_024147850.1 DUF932 domain-containing protein -
LDB15_RS22705 (51870) 51870..52085 - 216 WP_000111575.1 hypothetical protein -
LDB15_RS22710 (52174) 52174..52443 - 270 WP_000779465.1 hypothetical protein -
LDB15_RS22715 (53067) 53067..53486 - 420 WP_052124776.1 DUF192 domain-containing protein -
LDB15_RS22720 (54240) 54240..55127 - 888 WP_000130255.1 replication protein RepA -
LDB15_RS22725 (55160) 55160..55744 - 585 WP_000690619.1 Tn3 family transposase TnpR_TnShfr1 Transposase
LDB15_RS22730 (55744) 55744..56166 - 423 WP_000838908.1 hypothetical protein -
LDB15_RS22735 (56628) 56628..56873 + 246 WP_000195442.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
LDB15_RS22740 (56873) 56873..57415 + 543 WP_000711249.1 hypothetical protein -
LDB15_RS22745 (57424) 57424..57681 + 258 WP_024249949.1 hypothetical protein -
LDB15_RS22750 (57671) 57671..57997 + 327 WP_000817647.1 endoribonuclease MazF -
LDB15_RS22755 (58023) 58023..58337 + 315 WP_001280992.1 hypothetical protein -
LDB15_RS22760 (58397) 58397..58633 - 237 WP_049824326.1 Hha/YmoA family nucleoid-associated regulatory protein -
LDB15_RS22765 (58799) 58799..59524 - 726 WP_015345246.1 restriction endonuclease -
LDB15_RS22770 (59500) 59500..59814 - 315 WP_000851068.1 hypothetical protein -
LDB15_RS22775 (59817) 59817..60134 - 318 WP_001226231.1 TrbM/KikA/MpfK family conjugal transfer protein -
LDB15_RS22780 (60140) 60140..60577 - 438 WP_000034608.1 hypothetical protein -
LDB15_RS22785 (60589) 60589..60825 - 237 WP_000089855.1 H-NS histone family protein -
LDB15_RS22790 (60888) 60888..61628 + 741 WP_000815895.1 Type IV secretion system protein virB1 VF
LDB15_RS22795 (61651) 61651..61968 + 318 WP_001267114.1 hypothetical protein -
LDB15_RS22800 (61952) 61952..62242 + 291 WP_001090269.1 hypothetical protein VF
LDB15_RS22805 (62292) 62292..62606 + 315 WP_001053888.1 hypothetical protein VF
LDB15_RS22810 (62963) 62963..65236 + 2274 WP_231225962.1 Type IV secretion system protein virB4 VF
LDB15_RS22815 (65246) 65246..65602 + 357 WP_250690639.1 Type IV secretion system protein virB5 VF
LDB15_RS22820 (65649) 65649..66353 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LDB15_RS22825 (66406) 66406..67647 + 1242 Protein_99 type-F conjugative transfer system mating-pair stabilization protein TraN -
LDB15_RS22830 (67674) 67674..67931 + 258 WP_053913405.1 conjugal transfer protein TrbE -
LDB15_RS22835 (67924) 67924..68667 + 744 WP_015059017.1 type-F conjugative transfer system pilin assembly protein TraF -
LDB15_RS22840 (68828) 68828..69064 + 237 WP_000270010.1 type-F conjugative transfer system pilin chaperone TraQ -
LDB15_RS22845 (69051) 69051..69596 + 546 WP_000059817.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
LDB15_RS22850 (69586) 69586..69900 + 315 WP_001384255.1 P-type conjugative transfer protein TrbJ -
LDB15_RS22855 (69854) 69854..70246 + 393 WP_000126338.1 F-type conjugal transfer protein TrbF -
LDB15_RS22860 (70233) 70233..71606 + 1374 WP_000944325.1 conjugal transfer pilus assembly protein TraH -
LDB15_RS22865 (71603) 71603..74419 + 2817 WP_015059018.1 conjugal transfer mating-pair stabilization protein TraG -
LDB15_RS22870 (74452) 74452..74973 + 522 WP_000632668.1 conjugal transfer entry exclusion protein TraS -
LDB15_RS22875 (74998) 74998..75729 + 732 WP_021559024.1 conjugal transfer complement resistance protein TraT -
LDB15_RS22880 (75932) 75932..76669 + 738 WP_015059020.1 hypothetical protein -
LDB15_RS22885 (76720) 76720..78936 + 2217 WP_059274178.1 type IV conjugative transfer system coupling protein TraD -
LDB15_RS22890 (78936) 78936..84071 + 5136 WP_071177725.1 Multifunctional conjugation protein TraI Relaxase
LDB15_RS22895 (84105) 84105..84809 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LDB15_RS22900 (84872) 84872..85132 + 261 Protein_114 chemotaxis protein -
LDB15_RS22905 (85196) 85196..85900 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LDB15_RS22910 (85954) 85954..86277 - 324 Protein_116 class II aldolase/adducin family protein -
LDB15_RS22915 (86270) 86270..87522 - 1253 Protein_117 four-carbon acid sugar kinase family protein -
LDB15_RS22920 (87534) 87534..88436 - 903 WP_002903955.1 NAD(P)-dependent oxidoreductase -
LDB15_RS22925 (88697) 88697..89458 + 762 WP_002210513.1 DeoR/GlpR family DNA-binding transcription regulator -
LDB15_RS22930 (89479) 89479..90339 - 861 WP_004176269.1 Beta-lactamase SHV-1 ARG
LDB15_RS22935 (90476) 90476..90544 + 69 Protein_121 IS6 family transposase -
LDB15_RS22940 (90580) 90580..93546 - 2967 WP_001138014.1 Tn3 family transposase TnpA_TnAs1 Transposase
LDB15_RS22945 (93550) 93550..94110 - 561 WP_001161490.1 Tn3 family transposase TnpR_TnAs1 Transposase
LDB15_RS22950 (94502) 94502..95119 + 618 Protein_124 replication protein -
LDB15_RS22955 (95653) 95653..95931 + 279 WP_013213990.1 hypothetical protein -
LDB15_RS22960 (96042) 96042..96467 + 426 WP_013213989.1 antirestriction protein -
LDB15_RS22965 (96595) 96595..96750 + 156 WP_013213988.1 hypothetical protein -
LDB15_RS22970 (96796) 96796..97092 + 297 WP_013213987.1 transcriptional regulator -
LDB15_RS22975 (97196) 97196..98077 + 882 Protein_129 IS1182 family transposase ISKpn6 Transposase
LDB15_RS22980 (98327) 98327..99208 - 882 WP_004199234.1 Carbapenem-hydrolyzing beta-lactamase KPC ARG
LDB15_RS22985 (99484) 99484..100464 - 981 WP_013213985.1 IS481 family transposase ISKpn27 Transposase
LDB15_RS22990 (100587) 100587..101048 - 462 Protein_132 Tn3 family transposase TnpR_Tn3 Transposase
LDB15_RS22995 (101100) 101100..101804 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LDB15_RS23000 (101869) 101869..103041 - 1173 Protein_134 transposase -
LDB15_RS23005 (103116) 103116..103784 - 669 WP_001300294.1 putative signaling protein VF
LDB15_RS23010 (103820) 103820..104056 - 237 WP_000993386.1 broad-spectrum mercury transporter MerE -
LDB15_RS23015 (104053) 104053..104415 - 363 WP_001277456.1 mercury resistance co-regulator MerD -
LDB15_RS23020 (104433) 104433..106127 - 1695 WP_000105636.1 mercury(II) reductase -
LDB15_RS23025 (106179) 106179..106601 - 423 WP_001340589.1 organomercurial transporter MerC -
LDB15_RS23030 (106637) 106637..106912 - 276 WP_000732292.1 mercury resistance system periplasmic binding protein MerP -
LDB15_RS23035 (106926) 106926..107276 - 351 WP_001294663.1 mercuric transport protein MerT -
LDB15_RS23040 (107348) 107348..107782 + 435 WP_000429836.1 IS607 family transposase ISChh1 Transposase
LDB15_RS23045 (107861) 107861..108865 + 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
LDB15_RS23050 (109145) 109145..109417 - 273 Protein_144 transposase -
LDB15_RS23060 (110399) 110399..111421 - 1023 WP_000361404.1 helicase UvrD -
LDB15_RS23065 (111406) 111406..112968 - 1563 WP_004206609.1 AAA family ATPase -
LDB15_RS23070 (113042) 113042..113458 - 417 WP_001044770.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
LDB15_RS23075 (113455) 113455..113685 - 231 WP_001261282.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
LDB15_RS23080 (113642) 113642..114103 + 462 WP_014343465.1 hypothetical protein -
LDB15_RS23085 (114264) 114264..115208 + 945 WP_011977810.1 hypothetical protein -
LDB15_RS23090 (115245) 115245..115637 + 393 WP_011977811.1 hypothetical protein -
LDB15_RS23095 (115695) 115695..116216 + 522 WP_013214008.1 hypothetical protein -
LDB15_RS23100 (116262) 116262..116465 + 204 WP_011977813.1 hypothetical protein -
LDB15_RS23105 (116495) 116495..117499 + 1005 WP_011977814.1 hypothetical protein -
LDB15_RS23110 (117683) 117683..118462 + 780 WP_013214009.1 site-specific integrase -
LDB15_RS23115 (118508) 118508..118765 - 258 WP_013214010.1 hypothetical protein -
LDB15_RS23120 (118894) 118894..119007 - 114 WP_014343462.1 hypothetical protein -
LDB15_RS23125 (119543) 119543..120409 + 867 WP_004118283.1 replication initiation protein -
LDB15_RS23130 (121519) 121519..122724 + 1206 WP_011977818.1 AAA family ATPase -
LDB15_RS23135 (122724) 122724..123698 + 975 WP_011977819.1 ParB family protein -
LDB15_RS23140 (123780) 123780..125051 - 1272 WP_013214011.1 Y-family DNA polymerase -
LDB15_RS23145 (125051) 125051..125482 - 432 WP_001568036.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
LDB15_RS23150 (125889) 125889..127376 + 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
LDB15_RS23155 (127625) 127625..128596 + 972 WP_004152353.1 plasmid segregation protein ParM -
LDB15_RS23160 (128599) 128599..129270 + 672 WP_013214012.1 plasmid partitioning/stability family protein -
LDB15_RS23165 (129333) 129333..129563 + 231 WP_001568040.1 hypothetical protein -
LDB15_RS23170 (129759) 129759..129928 + 170 Protein_168 hypothetical protein -
LDB15_RS23175 (130000) 130000..130701 + 702 WP_001568041.1 DNA methylase -
LDB15_RS23180 (130701) 130701..130922 + 222 WP_001568042.1 hypothetical protein -
LDB15_RS23185 (130932) 130932..131351 + 420 WP_001568043.1 DUF1380 domain-containing protein -
LDB15_RS23190 (131405) 131405..132172 + 768 WP_013214013.1 hypothetical protein -
LDB15_RS23195 (132853) 132853..133281 + 429 WP_001568045.1 antirestriction protein -
LDB15_RS23200 (133324) 133324..133830 + 507 WP_013214014.1 antirestriction protein ArdA -
LDB15_RS23205 (133873) 133873..134064 + 192 WP_001568047.1 hypothetical protein -
LDB15_RS23210 (134252) 134252..134506 + 255 WP_011977779.1 DNA polymerase III subunit theta -
LDB15_RS23215 (134541) 134541..134861 + 321 WP_001568049.1 hypothetical protein -
LDB15_RS23220 (135541) 135541..135768 + 228 WP_001568050.1 hypothetical protein -
LDB15_RS23225 (135860) 135860..136090 + 231 WP_001568051.1 hypothetical protein -
LDB15_RS23230 (136142) 136142..137497 + 1356 WP_014343515.1 DUF3560 domain-containing protein -
LDB15_RS23235 (137545) 137545..138108 + 564 WP_014343514.1 methyltransferase -
LDB15_RS23240 (138941) 138941..139483 + 543 WP_014343512.1 single-stranded DNA-binding protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance