MGE detailed information
MGE type: Conjugative plasmid MGE length: 137647 bp
Accession: NZ_CP083890 Location: 1..137647 Organism: Escherichia coli strain NDM1 Replicon: plasmid unnamed2
Accession: NZ_CP083890 Location: 1..137647 Organism: Escherichia coli strain NDM1 Replicon: plasmid unnamed2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LCE25_RS24535 (7) | 7..935 | + | 929 | Protein_1 | tyrosine-type recombinase/integrase | - |
| LCE25_RS24540 (1086) | 1086..1910 | + | 825 | WP_001238928.1 | conjugal transfer protein TraE | - |
| LCE25_RS24545 (1995) | 1995..3197 | + | 1203 | WP_000976351.1 | conjugal transfer protein TraF | - |
| LCE25_RS24550 (3257) | 3257..3841 | + | 585 | WP_000977522.1 | histidine phosphatase family protein | - |
| LCE25_RS24555 (4236) | 4236..4692 | + | 457 | Protein_5 | hypothetical protein | VF |
| LCE25_RS24560 (4689) | 4689..5507 | + | 819 | WP_000646098.1 | hypothetical protein | VF |
| LCE25_RS24565 (5504) | 5504..6652 | + | 1149 | WP_001024972.1 | putative protein YggR | VF |
| LCE25_RS24570 (6649) | 6649..6939 | + | 291 | WP_001299214.1 | hypothetical protein | - |
| LCE25_RS24575 (6954) | 6954..7505 | + | 552 | WP_000014584.1 | Phospholipase D | VF |
| LCE25_RS24580 (7595) | 7595..11358 | + | 3764 | Protein_10 | DUF5710 domain-containing protein | - |
| LCE25_RS24585 (11376) | 11376..11723 | + | 348 | WP_001055900.1 | conjugal transfer protein | - |
| LCE25_RS24590 (11720) | 11720..12412 | + | 693 | WP_000138552.1 | DotI/IcmL family type IV secretion protein | - |
| LCE25_RS24595 (12423) | 12423..13406 | + | 984 | WP_001191878.1 | hypothetical protein | VF |
| LCE25_RS24600 (13409) | 13409..14698 | + | 1290 | WP_001271997.1 | conjugal transfer protein TraO | - |
| LCE25_RS24605 (14698) | 14698..15401 | + | 704 | Protein_15 | IncI1-type conjugal transfer protein TraP | - |
| LCE25_RS24610 (15401) | 15401..15928 | + | 528 | WP_001055569.1 | conjugal transfer protein TraQ | - |
| LCE25_RS24615 (15979) | 15979..16383 | + | 405 | WP_000086960.1 | IncI1-type conjugal transfer protein TraR | - |
| LCE25_RS24620 (16447) | 16447..16635 | + | 189 | WP_001277255.1 | putative conjugal transfer protein TraS | - |
| LCE25_RS24625 (16619) | 16619..17417 | + | 799 | Protein_19 | IncI1-type conjugal transfer protein TraT | - |
| LCE25_RS24630 (17507) | 17507..20554 | + | 3048 | WP_224446624.1 | IncI1-type conjugal transfer protein TraU | - |
| LCE25_RS24635 (20554) | 20554..21168 | + | 615 | WP_000337394.1 | IncI1-type conjugal transfer protein TraV | - |
| LCE25_RS24640 (21135) | 21135..22337 | + | 1203 | WP_001189158.1 | IncI1-type conjugal transfer protein TraW | - |
| LCE25_RS24645 (22366) | 22366..22949 | + | 584 | Protein_23 | conjugal transfer protein TraX | - |
| LCE25_RS24650 (23046) | 23046..25214 | + | 2169 | WP_000698368.1 | DotA/TraY family protein | - |
| LCE25_RS24655 (25285) | 25285..25947 | + | 663 | WP_000644794.1 | plasmid IncI1-type surface exclusion protein ExcA | - |
| LCE25_RS24660 (26019) | 26019..26228 | - | 210 | WP_000062603.1 | HEAT repeat domain-containing protein | - |
| LCE25_RS24665 (26620) | 26620..26796 | + | 177 | WP_001054900.1 | hypothetical protein | - |
| - (27282) | 27282..27333 | + | 52 | NuclAT_1 | - | - |
| - (27282) | 27282..27333 | + | 52 | NuclAT_1 | - | - |
| - (27282) | 27282..27333 | + | 52 | NuclAT_1 | - | - |
| - (27282) | 27282..27333 | + | 52 | NuclAT_1 | - | - |
| LCE25_RS24670 (27720) | 27720..27971 | + | 252 | WP_001291965.1 | hypothetical protein | - |
| LCE25_RS24675 (28043) | 28043..28195 | - | 153 | WP_001303307.1 | Hok/Gef family protein | Toxin Detail |
| - (28245) | 28245..28307 | + | 63 | NuclAT_0 | - | Antitoxin Detail |
| - (28245) | 28245..28307 | + | 63 | NuclAT_0 | - | Antitoxin Detail |
| - (28245) | 28245..28307 | + | 63 | NuclAT_0 | - | Antitoxin Detail |
| - (28245) | 28245..28307 | + | 63 | NuclAT_0 | - | Antitoxin Detail |
| LCE25_RS24680 (28487) | 28487..29695 | + | 1209 | WP_000121273.1 | IncI1-type conjugal transfer protein TrbA | - |
| LCE25_RS24685 (29714) | 29714..30784 | + | 1071 | WP_000151575.1 | IncI1-type conjugal transfer protein TrbB | - |
| LCE25_RS24690 (30777) | 30777..33068 | + | 2292 | WP_001289271.1 | F-type conjugative transfer protein TrbC | - |
| LCE25_RS24695 (33105) | 33105..35804 | - | 2700 | WP_001474686.1 | Protein TraI | Relaxase |
| LCE25_RS24700 (35815) | 35815..36147 | - | 333 | WP_001283947.1 | IncI1-type relaxosome accessory protein NikA | - |
| LCE25_RS24705 (36381) | 36381..36716 | + | 336 | WP_000157086.1 | molybdopterin-guanine dinucleotide biosynthesis protein MobC | - |
| LCE25_RS24710 (36802) | 36802..37650 | - | 849 | WP_001077027.1 | DUF4942 domain-containing protein | - |
| LCE25_RS24715 (38230) | 38230..38481 | + | 252 | WP_000148286.1 | helix-turn-helix transcriptional regulator | - |
| LCE25_RS24720 (38512) | 38512..38793 | - | 282 | WP_001334682.1 | hypothetical protein | VF |
| LCE25_RS24725 (38793) | 38793..39695 | - | 903 | WP_000038404.1 | Recombination-promoting nuclease RpnA | VF |
| LCE25_RS24730 (39760) | 39760..40026 | - | 267 | WP_001247862.1 | hypothetical protein | - |
| LCE25_RS24735 (40120) | 40120..40554 | - | 435 | WP_000218863.1 | hypothetical protein | - |
| LCE25_RS24740 (41283) | 41283..41783 | - | 501 | WP_000117611.1 | antirestriction protein ArdA | - |
| LCE25_RS24745 (42230) | 42230..43405 | - | 1176 | WP_000942657.1 | IS200-IS605 family transposase ISEc46 | Transposase |
| LCE25_RS24750 (43535) | 43535..44254 | - | 720 | WP_001276260.1 | plasmid SOS inhibition protein A | - |
| LCE25_RS24755 (44251) | 44251..44685 | - | 435 | WP_000845897.1 | conjugation system SOS inhibitor PsiB | - |
| LCE25_RS24760 (44740) | 44740..46701 | - | 1962 | WP_224446625.1 | ParB/RepB/Spo0J family partition protein | - |
| LCE25_RS24765 (46760) | 46760..46993 | - | 234 | WP_000006012.1 | DUF905 family protein | - |
| LCE25_RS24770 (47051) | 47051..47578 | - | 528 | WP_001276116.1 | single-stranded DNA-binding protein | - |
| LCE25_RS25665 (47947) | 47947..48015 | + | 69 | Protein_49 | pilus protein | - |
| LCE25_RS24780 (48348) | 48348..48539 | - | 192 | WP_001027500.1 | hypothetical protein | - |
| LCE25_RS24785 (48536) | 48536..48958 | - | 423 | WP_000271725.1 | DUF1380 family protein | - |
| LCE25_RS24790 (49005) | 49005..49430 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| LCE25_RS24795 (49848) | 49848..50618 | - | 771 | WP_024133193.1 | hypothetical protein | - |
| LCE25_RS24800 (50669) | 50669..51155 | - | 487 | Protein_54 | DUF1380 domain-containing protein | - |
| LCE25_RS24805 (51115) | 51115..51336 | - | 222 | WP_001104887.1 | hypothetical protein | - |
| LCE25_RS24810 (51337) | 51337..52020 | - | 684 | WP_000086178.1 | DNA methylase | - |
| LCE25_RS24815 (52097) | 52097..52408 | - | 312 | WP_010891263.1 | hypothetical protein | - |
| LCE25_RS24820 (52405) | 52405..53307 | - | 903 | WP_000273918.1 | DUF1281 domain-containing protein | - |
| LCE25_RS24825 (53988) | 53988..54380 | - | 393 | WP_000272884.1 | plasmid partitioning/stability family protein | - |
| LCE25_RS24830 (54384) | 54384..55358 | - | 975 | WP_001217836.1 | plasmid segregation protein ParM | - |
| LCE25_RS24835 (55597) | 55597..55971 | - | 375 | WP_000752652.1 | hypothetical protein | - |
| LCE25_RS24840 (55971) | 55971..56603 | - | 633 | WP_000312331.1 | ParA family protein | - |
| LCE25_RS24845 (57187) | 57187..57972 | - | 786 | WP_001164192.1 | site-specific integrase | - |
| LCE25_RS24850 (57974) | 57974..58387 | - | 414 | WP_000465034.1 | hypothetical protein | - |
| LCE25_RS24855 (58956) | 58956..59216 | + | 261 | WP_000343102.1 | hypothetical protein | - |
| LCE25_RS24860 (59213) | 59213..59803 | + | 591 | WP_000194555.1 | hypothetical protein | - |
| LCE25_RS24865 (59821) | 59821..60168 | - | 348 | WP_000142424.1 | DUF6404 family protein | - |
| LCE25_RS24870 (60287) | 60287..60634 | + | 348 | WP_000762580.1 | colicin E1 family microcin immunity protein | - |
| LCE25_RS24875 (60652) | 60652..62532 | - | 1881 | WP_001283356.1 | colicin Ia central receptor-binding domain-containing protein | - |
| LCE25_RS24880 (62811) | 62811..64157 | - | 1347 | WP_196236969.1 | protein YagA | - |
| LCE25_RS24885 (64511) | 64511..65113 | + | 603 | WP_000517689.1 | ProQ/FINO family protein | - |
| LCE25_RS24890 (65169) | 65169..65663 | + | 495 | WP_001442119.1 | hypothetical protein | - |
| LCE25_RS24895 (65663) | 65663..65929 | + | 267 | WP_000627831.1 | hypothetical protein | - |
| LCE25_RS24900 (66406) | 66406..66810 | - | 405 | WP_044568872.1 | hypothetical protein | - |
| LCE25_RS24905 (67075) | 67075..68077 | - | 1003 | Protein_75 | IS110 family transposase IS4321R | Transposase |
| LCE25_RS24910 (68156) | 68156..71122 | - | 2967 | WP_224446626.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| LCE25_RS24915 (71125) | 71125..71685 | - | 561 | WP_000147567.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| LCE25_RS24920 (71811) | 71811..72161 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| LCE25_RS24925 (72364) | 72364..73377 | - | 1014 | WP_000845048.1 | class 1 integron integrase IntI1 | - |
| LCE25_RS24930 (73544) | 73544..74386 | + | 843 | WP_001456218.1 | alpha/beta fold putative hydrolase EstX | - |
| LCE25_RS24935 (74533) | 74533..75090 | + | 558 | WP_134894556.1 | HAD family hydrolase | - |
| LCE25_RS24940 (75148) | 75148..75986 | + | 839 | Protein_82 | Streptomycin 3''-adenylyltransferase | ARG |
| LCE25_RS24945 (76201) | 76201..77460 | + | 1260 | WP_000095725.1 | Bicyclomycin resistance protein | ARG |
| LCE25_RS24950 (77553) | 77553..78391 | + | 839 | Protein_84 | Streptomycin 3''-adenylyltransferase | ARG |
| LCE25_RS24955 (78514) | 78514..78846 | + | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| LCE25_RS24960 (79093) | 79093..79371 | - | 279 | WP_224446627.1 | transposase | - |
| LCE25_RS24965 (79426) | 79426..82431 | - | 3006 | WP_001143775.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| LCE25_RS24970 (82593) | 82593..83150 | + | 558 | WP_001217881.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| LCE25_RS24975 (83333) | 83333..84193 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| LCE25_RS24980 (84355) | 84355..85170 | + | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| LCE25_RS24985 (85231) | 85231..86034 | + | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| LCE25_RS24990 (86034) | 86034..86870 | + | 837 | WP_000480968.1 | hypothetical protein | ARG |
| LCE25_RS24995 (87176) | 87176..87418 | + | 243 | WP_000844627.1 | transposase | - |
| LCE25_RS25000 (87450) | 87450..88100 | - | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| LCE25_RS25005 (88206) | 88206..89405 | + | 1200 | WP_000804064.1 | tetracycline efflux MFS transporter Tet(A) | - |
| LCE25_RS25010 (89437) | 89437..90297 | - | 861 | WP_000493383.1 | EamA family transporter | - |
| LCE25_RS25015 (90306) | 90306..90920 | - | 615 | Protein_97 | transposase | - |
| LCE25_RS25020 (90915) | 90915..91040 | + | 126 | Protein_98 | MerR family transcriptional regulator | - |
| LCE25_RS25025 (91119) | 91119..92129 | + | 1011 | WP_224446622.1 | IS110 family transposase IS4321R | Transposase |
| LCE25_RS25030 (92610) | 92610..93458 | - | 849 | WP_001057996.1 | 3'-5' exonuclease | - |
| LCE25_RS25035 (93498) | 93498..93776 | - | 279 | WP_001384452.1 | type II toxin-antitoxin system toxin YacB | Toxin Detail |
| LCE25_RS25040 (93776) | 93776..94045 | - | 270 | WP_000079941.1 | type II toxin-antitoxin system antitoxin YacA | Antitoxin Detail |
| LCE25_RS25045 (94100) | 94100..94258 | - | 159 | WP_000841008.1 | hypothetical protein | - |
| LCE25_RS25050 (94954) | 94954..95985 | - | 1032 | WP_000907873.1 | plasmid replication initiator RepA | - |
| LCE25_RS25055 (96991) | 96991..97221 | + | 231 | WP_228772074.1 | ash family protein | - |
| LCE25_RS25060 (97139) | 97139..97426 | + | 288 | WP_000074849.1 | conjugal transfer protein TraA | - |
| LCE25_RS25065 (97868) | 97868..98401 | + | 534 | WP_001303319.1 | transcription termination/antitermination NusG family protein | - |
| LCE25_RS25070 (98655) | 98655..99338 | + | 684 | WP_000213857.1 | conjugal transfer protein TraC | - |
| LCE25_RS25075 (99352) | 99352..99918 | + | 567 | WP_000776428.1 | protein TraD | - |
| LCE25_RS25080 (100186) | 100186..100440 | + | 255 | WP_001136192.1 | PilI type IV pilus biogenesis protein | - |
| LCE25_RS25085 (100483) | 100483..100935 | + | 453 | WP_000008892.1 | hypothetical protein | - |
| LCE25_RS25090 (101609) | 101609..102676 | + | 1068 | WP_000742600.1 | hypothetical protein | VF |
| LCE25_RS25095 (102676) | 102676..103113 | + | 438 | WP_000539807.1 | hypothetical protein | VF |
| LCE25_RS25100 (103127) | 103127..104809 | + | 1683 | WP_000748143.1 | Outer membrane lipoprotein BfpB | VF |
| LCE25_RS25105 (104802) | 104802..106097 | + | 1296 | WP_000752774.1 | type 4b pilus protein PilO2 | - |
| LCE25_RS25110 (106084) | 106084..106536 | + | 453 | WP_001247336.1 | hypothetical protein | VF |
| LCE25_RS25115 (106547) | 106547..108100 | + | 1554 | WP_000362202.1 | Toxin coregulated pilus biosynthesis protein T | VF |
| LCE25_RS25120 (108113) | 108113..109210 | + | 1098 | WP_001208805.1 | Toxin coregulated pilus biosynthesis protein E | VF |
| LCE25_RS25125 (109228) | 109228..109842 | + | 615 | WP_000959785.1 | hypothetical protein | VF |
| LCE25_RS25130 (109852) | 109852..110412 | + | 561 | WP_000014116.1 | hypothetical protein | VF |
| LCE25_RS25135 (110397) | 110397..111053 | + | 657 | WP_001193553.1 | hypothetical protein | VF |
| LCE25_RS25140 (111053) | 111053..112345 | + | 1293 | WP_032274560.1 | hypothetical protein | VF |
| LCE25_RS25145 (112342) | 112342..112590 | - | 249 | WP_001349157.1 | hypothetical protein | - |
| LCE25_RS25150 (113281) | 113281..114435 | + | 1155 | WP_001139958.1 | site-specific integrase | - |
| LCE25_RS25155 (114586) | 114586..115410 | + | 825 | WP_001238928.1 | conjugal transfer protein TraE | - |
| LCE25_RS25160 (115495) | 115495..116696 | + | 1202 | Protein_126 | conjugal transfer protein TraF | - |
| LCE25_RS25165 (116756) | 116756..117340 | + | 585 | WP_000977522.1 | histidine phosphatase family protein | - |
| LCE25_RS25170 (117735) | 117735..118193 | + | 459 | WP_001079808.1 | hypothetical protein | VF |
| LCE25_RS25175 (118190) | 118190..119006 | + | 817 | Protein_129 | hypothetical protein | VF |
| LCE25_RS25180 (119003) | 119003..120150 | + | 1148 | Protein_130 | putative protein YggR | VF |
| LCE25_RS25185 (120147) | 120147..120437 | + | 291 | WP_001299214.1 | hypothetical protein | - |
| LCE25_RS25190 (120452) | 120452..121003 | + | 552 | WP_000014584.1 | Phospholipase D | VF |
| LCE25_RS25195 (121093) | 121093..124859 | + | 3767 | Protein_133 | DUF5710 domain-containing protein | - |
| LCE25_RS25200 (124877) | 124877..125224 | + | 348 | WP_001055900.1 | conjugal transfer protein | - |
| LCE25_RS25205 (125221) | 125221..125913 | + | 693 | WP_000138552.1 | DotI/IcmL family type IV secretion protein | - |
| LCE25_RS25210 (125924) | 125924..126907 | + | 984 | WP_001191878.1 | hypothetical protein | VF |
| LCE25_RS25215 (126910) | 126910..128199 | + | 1290 | WP_001271997.1 | conjugal transfer protein TraO | - |
| LCE25_RS25220 (128199) | 128199..128903 | + | 705 | WP_000801920.1 | IncI1-type conjugal transfer protein TraP | - |
| LCE25_RS25225 (128903) | 128903..129430 | + | 528 | WP_001055569.1 | conjugal transfer protein TraQ | - |
| LCE25_RS25230 (129481) | 129481..129885 | + | 405 | WP_000086960.1 | IncI1-type conjugal transfer protein TraR | - |
| LCE25_RS25235 (129948) | 129948..130136 | + | 189 | WP_001277255.1 | putative conjugal transfer protein TraS | - |
| LCE25_RS25240 (130120) | 130120..130920 | + | 801 | WP_001164788.1 | IncI1-type conjugal transfer protein TraT | - |
| LCE25_RS25245 (131010) | 131010..134058 | + | 3049 | Protein_143 | IncI1-type conjugal transfer protein TraU | - |
| LCE25_RS25250 (134058) | 134058..134672 | + | 615 | WP_000337394.1 | IncI1-type conjugal transfer protein TraV | - |
| LCE25_RS25255 (134639) | 134639..135841 | + | 1203 | WP_001189158.1 | IncI1-type conjugal transfer protein TraW | - |
| LCE25_RS25260 (135870) | 135870..136454 | + | 585 | WP_001037998.1 | conjugal transfer protein TraX | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|