NZ_CP0838781..158041

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 158041 bp
Accession: NZ_CP083878        Location: 1..158041         Organism: Escherichia coli strain NDM4       Replicon: plasmid unnamed1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LCE22_RS22855 (2) 2..556 + 555 Protein_0 ParB/RepB/Spo0J family plasmid partition protein -
LCE22_RS22860 (1422) 1422..2324 + 903 WP_001507408.1 DUF1281 domain-containing protein -
LCE22_RS22865 (2321) 2321..2632 + 312 WP_032260558.1 hypothetical protein -
LCE22_RS22870 (2706) 2706..3389 + 684 WP_000086148.1 DNA methylase -
LCE22_RS22875 (3390) 3390..3611 + 222 WP_001104867.1 hypothetical protein -
LCE22_RS22880 (3592) 3592..4059 + 468 WP_223368614.1 DUF1380 family protein -
LCE22_RS22885 (4110) 4110..4890 + 781 Protein_6 hypothetical protein -
LCE22_RS22890 (5307) 5307..5732 + 426 WP_001198941.1 antirestriction protein -
LCE22_RS22895 (5702) 5702..6193 + 492 WP_223368613.1 DUF1380 domain-containing protein -
LCE22_RS22900 (6193) 6193..6384 + 192 WP_001027495.1 hypothetical protein -
LCE22_RS22905 (6746) 6746..6896 - 151 Protein_10 hypothetical protein -
LCE22_RS22910 (7413) 7413..7643 + 231 WP_000218642.1 hypothetical protein -
LCE22_RS22915 (7696) 7696..9057 + 1362 WP_086352864.1 DUF3560 domain-containing protein -
LCE22_RS22920 (9105) 9105..9667 + 563 Protein_13 class I SAM-dependent methyltransferase -
LCE22_RS22925 (9753) 9753..9929 - 177 Protein_14 pilus protein -
LCE22_RS22930 (10042) 10042..11709 - 1668 WP_012372796.1 group II intron reverse transcriptase/maturase -
LCE22_RS22935 (13371) 13371..13940 - 570 WP_089634947.1 hypothetical protein -
LCE22_RS22945 (15244) 15244..16002 + 759 Protein_18 site-specific integrase -
LCE22_RS22950 (16177) 16177..17172 + 996 WP_224434102.1 substrate-binding domain-containing protein -
LCE22_RS22955 (17268) 17268..19393 + 2126 Protein_20 alpha-galactosidase -
LCE22_RS22960 (19456) 19456..20733 + 1278 WP_001083369.1 MFS transporter -
LCE22_RS22965 (20730) 20730..22163 + 1434 WP_024170639.1 glycoside hydrolase family 32 protein -
LCE22_RS22970 (22358) 22358..23752 + 1395 WP_001037799.1 carbohydrate porin -
LCE22_RS22975 (23998) 23998..24102 - 105 Protein_24 thiosulfate reductase cytochrome B subunit -
LCE22_RS22980 (24159) 24159..24852 + 694 Protein_25 IS1 family transposase -
LCE22_RS22985 (24979) 24979..25491 + 513 WP_223350513.1 potassium channel family protein -
LCE22_RS22990 (25576) 25576..25827 + 252 Protein_27 iron-containing alcohol dehydrogenase -
LCE22_RS22995 (26116) 26116..26433 - 318 Protein_28 IS110 family transposase IS1618 Transposase
LCE22_RS23000 (26588) 26588..26693 + 106 Protein_29 plasmid SOS inhibition protein A -
- (26662) 26662..26860 + 199 NuclAT_0 - Antitoxin Detail
- (26662) 26662..26860 + 199 NuclAT_0 - Antitoxin Detail
- (26662) 26662..26860 + 199 NuclAT_0 - Antitoxin Detail
- (26662) 26662..26860 + 199 NuclAT_0 - Antitoxin Detail
LCE22_RS23005 (26867) 26867..27016 + 150 Protein_30 DUF5431 family protein -
LCE22_RS23010 (26967) 26967..27083 + 117 WP_001375150.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
LCE22_RS23015 (27384) 27384..27681 - 298 Protein_32 hypothetical protein -
LCE22_RS23020 (27751) 27751..27957 + 207 WP_000275854.1 hypothetical protein -
LCE22_RS23025 (27982) 27982..28269 + 288 WP_000107242.1 hypothetical protein -
LCE22_RS23030 (28388) 28388..29209 + 822 WP_001234465.1 DUF932 domain-containing protein -
LCE22_RS23035 (29505) 29505..30077 - 573 WP_000949660.1 hypothetical protein VF
LCE22_RS23040 (30447) 30447..30830 + 384 WP_001063020.1 conjugal transfer relaxosome DNA-binding protein TraM -
LCE22_RS23045 (31021) 31021..31668 + 648 WP_000332520.1 conjugal transfer transcriptional regulator TraJ -
LCE22_RS23050 (31804) 31804..32019 + 216 WP_001352842.1 conjugal transfer relaxosome protein TraY -
LCE22_RS23055 (32062) 32062..32427 + 366 WP_000340282.1 type IV conjugative transfer system pilin TraA -
LCE22_RS23060 (32442) 32442..32753 + 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
LCE22_RS23065 (32775) 32775..33341 + 567 WP_000399790.1 type IV conjugative transfer system protein TraE -
LCE22_RS23070 (33328) 33328..34056 + 729 WP_001230813.1 type-F conjugative transfer system secretin TraK -
LCE22_RS23075 (34056) 34056..35483 + 1428 WP_001553836.1 F-type conjugal transfer pilus assembly protein TraB -
LCE22_RS23080 (35473) 35473..36063 + 591 WP_000002787.1 conjugal transfer pilus-stabilizing protein TraP -
LCE22_RS23085 (36050) 36050..36370 + 321 Protein_46 conjugal transfer protein TrbD -
LCE22_RS23090 (36363) 36363..36614 + 252 WP_001038342.1 conjugal transfer protein TrbG -
LCE22_RS23095 (36611) 36611..37126 + 516 WP_000809832.1 type IV conjugative transfer system lipoprotein TraV -
LCE22_RS23100 (37261) 37261..37482 + 222 WP_001278692.1 conjugal transfer protein TraR -
LCE22_RS23105 (37642) 37642..40269 + 2628 WP_039021964.1 type IV secretion system protein TraC -
LCE22_RS23110 (40266) 40266..40652 + 387 WP_000214092.1 type-F conjugative transfer system protein TrbI -
LCE22_RS23115 (40649) 40649..41281 + 633 WP_001203720.1 type-F conjugative transfer system protein TraW -
LCE22_RS23120 (41278) 41278..42270 + 993 WP_000830839.1 conjugal transfer pilus assembly protein TraU -
LCE22_RS23125 (42279) 42279..42917 + 639 WP_000777692.1 type-F conjugative transfer system pilin assembly protein TrbC -
LCE22_RS23130 (42914) 42914..44722 + 1809 WP_000821821.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
LCE22_RS23135 (44749) 44749..45006 + 258 WP_000864352.1 conjugal transfer protein TrbE -
LCE22_RS23140 (44999) 44999..45742 + 744 WP_001430248.1 type-F conjugative transfer system pilin assembly protein TraF -
LCE22_RS23145 (45756) 45756..46097 + 342 WP_000556794.1 conjugal transfer protein TrbA -
LCE22_RS23150 (46078) 46078..46413 - 336 WP_000415571.1 hypothetical protein -
LCE22_RS23155 (46494) 46494..46778 + 285 WP_000624105.1 type-F conjugative transfer system pilin chaperone TraQ -
LCE22_RS23160 (46765) 46765..47319 + 555 WP_001553830.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
LCE22_RS23165 (47249) 47249..47622 + 374 Protein_62 P-type conjugative transfer protein TrbJ -
LCE22_RS23170 (47576) 47576..47968 + 393 WP_001553828.1 F-type conjugal transfer protein TrbF -
LCE22_RS23175 (47955) 47955..49328 + 1374 WP_001553827.1 conjugal transfer pilus assembly protein TraH -
LCE22_RS23180 (49325) 49325..52150 + 2826 WP_001553826.1 conjugal transfer mating-pair stabilization protein TraG -
LCE22_RS23185 (52147) 52147..52656 + 510 WP_000628100.1 conjugal transfer entry exclusion protein TraS -
LCE22_RS23190 (52670) 52670..53401 + 732 WP_000850424.1 conjugal transfer complement resistance protein TraT -
LCE22_RS23195 (53653) 53653..55851 + 2199 WP_046464200.1 type IV conjugative transfer system coupling protein TraD -
LCE22_RS23200 (55851) 55851..60971 + 5121 WP_013362805.1 Multifunctional conjugation protein TraI Relaxase
LCE22_RS23205 (60991) 60991..61737 + 747 WP_187795572.1 conjugal transfer pilus acetylase TraX -
LCE22_RS23210 (61792) 61792..62352 + 561 WP_000139363.1 fertility inhibition protein FinO -
LCE22_RS23215 (62486) 62486..62698 + 213 WP_005012601.1 hypothetical protein -
LCE22_RS23220 (62999) 62999..63088 - 90 Protein_73 IS1 family transposase -
LCE22_RS23225 (63143) 63143..63820 + 678 WP_001339397.1 IS66 family transposase ISCro1 Transposase
LCE22_RS23230 (63820) 63820..64167 + 348 WP_000624622.1 IS66 family transposase ISCro1 Transposase
LCE22_RS23235 (64187) 64187..65758 + 1572 WP_023149734.1 IS66 family transposase ISCro1 Transposase
LCE22_RS23240 (65796) 65796..66412 - 617 Protein_77 IS1-like element IS1A family transposase -
LCE22_RS23245 (66513) 66513..66695 + 183 WP_000968309.1 hypothetical protein -
- (66834) 66834..66895 - 62 NuclAT_1 - -
- (66834) 66834..66895 - 62 NuclAT_1 - -
- (66834) 66834..66895 - 62 NuclAT_1 - -
- (66834) 66834..66895 - 62 NuclAT_1 - -
LCE22_RS23250 (66939) 66939..67088 + 150 WP_001312851.1 Hok/Gef family protein -
LCE22_RS23255 (67372) 67372..67629 + 258 WP_000083833.1 replication regulatory protein RepA -
LCE22_RS23260 (67865) 67865..67939 + 75 WP_032336874.1 RepA leader peptide Tap -
LCE22_RS23265 (67932) 67932..68378 + 447 Protein_82 plasmid replication initiator RepA -
LCE22_RS23270 (68378) 68378..68992 - 615 Protein_83 VENN motif pre-toxin domain-containing protein -
LCE22_RS23275 (69699) 69699..70919 + 1221 WP_000410951.1 arginine deiminase -
LCE22_RS23280 (70930) 70930..71841 + 912 WP_000440183.1 carbamate kinase -
LCE22_RS23285 (71926) 71926..72930 + 1005 WP_000154545.1 Ornithine carbamoyltransferase VF
LCE22_RS23290 (72978) 72978..74381 + 1404 WP_000514417.1 YfcC family protein -
LCE22_RS23295 (74462) 74462..74941 + 480 WP_001496175.1 ArgR family transcriptional regulator -
LCE22_RS23300 (75005) 75005..75193 - 189 Protein_89 transposase domain-containing protein -
LCE22_RS23305 (75254) 75254..76387 + 1134 WP_000555401.1 IS110 family transposase ISEc45 Transposase
LCE22_RS23310 (76641) 76641..76793 - 153 Protein_91 transposase -
LCE22_RS23315 (76796) 76796..76966 - 171 Protein_92 IS66 family transposase ISEc43 Transposase
LCE22_RS23320 (76997) 76997..77347 - 351 WP_000624725.1 IS66 family transposase ISEc47 Transposase
LCE22_RS23325 (77344) 77344..77700 - 357 WP_000229735.1 IS66 family transposase ISEc23 Transposase
LCE22_RS23335 (78545) 78545..79123 + 579 WP_032152936.1 DUF2726 domain-containing protein -
LCE22_RS23340 (79536) 79536..79889 - 354 WP_000005489.1 hypothetical protein -
LCE22_RS23345 (80361) 80361..81383 - 1023 WP_000156883.1 IS110 family transposase ISSm1 Transposase
LCE22_RS23350 (81788) 81788..82045 + 258 WP_000083821.1 replication regulatory protein RepA -
LCE22_RS23355 (82280) 82280..82354 + 75 WP_001365705.1 RepA leader peptide Tap -
LCE22_RS23360 (82347) 82347..83204 + 858 WP_032152935.1 incFII family plasmid replication initiator RepA -
LCE22_RS23365 (84143) 84143..84796 + 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
LCE22_RS23370 (84889) 84889..85146 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
LCE22_RS23375 (85079) 85079..85480 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
LCE22_RS23380 (85617) 85617..88514 - 2898 WP_001553819.1 Tn3 family transposase TnpA_Tn5403 Transposase
LCE22_RS23385 (88609) 88609..89214 + 606 WP_000509965.1 Tn3 family transposase TnpR_Tn5403 Transposase
LCE22_RS23390 (89238) 89238..89987 - 750 Protein_107 Tn3 family transposase TnpA_TnAs1 Transposase
LCE22_RS23395 (89991) 89991..90383 + 393 WP_001351729.1 isochorismatase family cysteine hydrolase -
LCE22_RS23400 (90521) 90521..91405 + 885 WP_000058717.1 EamA family transporter -
LCE22_RS23405 (91437) 91437..92636 - 1200 WP_000804064.1 Tetracycline resistance protein, class C ARG
LCE22_RS23410 (92742) 92742..93392 + 651 WP_000164043.1 tetracycline resistance transcriptional repressor TetR(A) -
LCE22_RS23415 (93424) 93424..93666 - 243 WP_032140899.1 hypothetical protein -
LCE22_RS23420 (93708) 93708..95222 - 1515 Protein_113 Tn3 family transposase TnpA_TnAs1 Transposase
LCE22_RS23425 (95288) 95288..95992 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LCE22_RS23430 (96136) 96136..96690 + 555 WP_063840321.1 Aminoglycoside N(6')-acetyltransferase type 1 ARG
LCE22_RS23435 (96821) 96821..97651 + 831 WP_001334766.1 Beta-lactamase OXA-1 ARG
LCE22_RS23440 (97789) 97789..98229 + 441 Protein_117 CatB-related O-acetyltransferase -
LCE22_RS23445 (98283) 98283..98987 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LCE22_RS23450 (99053) 99053..99340 + 288 Protein_119 IS1380 family transposase ISEcp1 Transposase
LCE22_RS23455 (99596) 99596..100471 + 876 WP_000239590.1 Beta-lactamase CTX-M-1 ARG
LCE22_RS23460 (100518) 100518..100850 - 333 WP_001393253.1 WbuC family cupin fold metalloprotein -
LCE22_RS23465 (100876) 100876..103095 + 2220 Protein_122 Tn3 family transposase TnpA_Tn3 Transposase
LCE22_RS23470 (103172) 103172..103876 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LCE22_RS23475 (103928) 103928..104392 + 465 Protein_124 IS6-like element IS6100 family transposase -
LCE22_RS23480 (104885) 104885..105469 - 585 WP_001137892.1 macrolide-binding transcriptional repressor MphR(A) -
LCE22_RS23485 (105469) 105469..106707 - 1239 WP_000004159.1 macrolide resistance MFS transporter Mrx(A) -
LCE22_RS23490 (106704) 106704..107618 - 915 WP_023063803.1 hypothetical protein ARG
LCE22_RS23495 (107740) 107740..108444 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LCE22_RS23500 (108609) 108609..108902 + 294 Protein_129 IS30 family transposase ISAba125 Transposase
LCE22_RS23505 (109003) 109003..109815 + 813 WP_023408309.1 Metallo-beta-lactamase type 2 ARG
LCE22_RS23510 (109819) 109819..110184 + 366 WP_004201167.1 bleomycin binding protein Ble-MBL -
LCE22_RS23515 (110189) 110189..110827 + 639 WP_004201168.1 phosphoribosylanthranilate isomerase -
LCE22_RS23520 (110838) 110838..111395 - 558 Protein_133 twin-arginine translocation (TAT) pathway signal sequence domain protein -
LCE22_RS23525 (111495) 111495..111869 - 375 Protein_134 protein-disulfide reductase DsbD family protein -
LCE22_RS23530 (112182) 112182..113723 - 1542 WP_000050481.1 IS91 family transposase ISVsa3 Transposase
LCE22_RS23535 (114128) 114128..114967 - 840 WP_000259031.1 Dihydropteroate synthase ARG
LCE22_RS23540 (114961) 114961..115308 - 348 WP_000679427.1 Multidrug transporter EmrE ARG
LCE22_RS23545 (115425) 115425..116263 - 839 Protein_138 Streptomycin 3''-adenylyltransferase ARG
LCE22_RS23550 (116269) 116269..116559 - 291 WP_001336345.1 DUF1010 domain-containing protein -
LCE22_RS23555 (116671) 116671..117168 - 498 WP_001083725.1 Dihydrofolate reductase ARG
LCE22_RS23560 (117313) 117313..118179 + 867 Protein_141 IS91 family transposase ISAzo26 Transposase
LCE22_RS23565 (118234) 118234..118938 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LCE22_RS23570 (119493) 119493..119777 + 285 WP_001387467.1 ribbon-helix-helix domain-containing protein Antitoxin Detail
LCE22_RS23575 (119777) 119777..120052 + 276 WP_000421272.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin Detail
LCE22_RS23585 (120935) 120935..121138 + 204 Protein_146 hypothetical protein -
LCE22_RS23590 (121263) 121263..121391 - 129 Protein_147 IS481 family transposase -
LCE22_RS23595 (121424) 121424..122593 - 1170 WP_001072355.1 hypothetical protein -
LCE22_RS23600 (123125) 123125..123393 + 269 Protein_149 type II toxin-antitoxin system ParD family antitoxin -
LCE22_RS23605 (123380) 123380..123669 + 290 Protein_150 type II toxin-antitoxin system RelE/ParE family toxin -
LCE22_RS23610 (123736) 123736..123918 + 183 WP_042344623.1 hypothetical protein -
LCE22_RS23615 (124039) 124039..124779 + 741 WP_001066953.1 tyrosine-type recombinase/integrase -
LCE22_RS23620 (125064) 125064..126041 - 978 WP_000361611.1 RepB family plasmid replication initiator protein -
LCE22_RS23625 (126798) 126798..127770 + 973 Protein_154 hypothetical protein -
LCE22_RS23630 (127929) 127929..128156 - 228 WP_013023899.1 abortive infection family protein -
LCE22_RS23635 (128235) 128235..128932 + 698 WP_224434100.1 IS1 family transposase IS1R Transposase
LCE22_RS23640 (129061) 129061..129758 + 698 WP_224434100.1 IS1-like element IS1B family transposase -
LCE22_RS23645 (129958) 129958..130890 - 933 WP_058682609.1 S-4TM family putative pore-forming effector -
LCE22_RS23650 (130894) 130894..131889 - 996 WP_000246636.1 hypothetical protein -
LCE22_RS23655 (132597) 132597..132815 + 219 WP_000813634.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin Detail
LCE22_RS23660 (132817) 132817..133122 + 306 WP_001159868.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
LCE22_RS23665 (133123) 133123..133929 + 807 WP_000016982.1 site-specific integrase -
LCE22_RS23670 (134703) 134703..135458 + 756 WP_000852146.1 replication initiation protein RepE -
LCE22_RS23675 (136046) 136046..137212 + 1167 WP_000772446.1 Sporulation initiation inhibitor protein Soj VF
LCE22_RS23680 (137212) 137212..138198 + 987 WP_224434101.1 ParB/RepB/Spo0J family plasmid partition protein -
LCE22_RS23685 (139054) 139054..139956 + 903 WP_001507408.1 DUF1281 domain-containing protein -
LCE22_RS23690 (139953) 139953..140264 + 312 WP_032260558.1 hypothetical protein -
LCE22_RS23695 (140340) 140340..141023 + 684 WP_000086148.1 DNA methylase -
LCE22_RS23700 (141024) 141024..141245 + 222 WP_001104867.1 hypothetical protein -
LCE22_RS23705 (141226) 141226..141693 + 468 WP_223368614.1 DUF1380 family protein -
LCE22_RS23710 (141744) 141744..142520 + 777 WP_001753849.1 hypothetical protein -
LCE22_RS23715 (142937) 142937..143362 + 426 WP_001198941.1 antirestriction protein -
LCE22_RS23720 (143332) 143332..143823 + 492 WP_223368613.1 DUF1380 domain-containing protein -
LCE22_RS23725 (143823) 143823..144014 + 192 WP_001027495.1 hypothetical protein -
LCE22_RS23730 (144376) 144376..144526 - 151 Protein_175 hypothetical protein -
LCE22_RS23735 (145043) 145043..145273 + 231 WP_000218642.1 hypothetical protein -
LCE22_RS23740 (145325) 145325..146685 + 1361 Protein_177 DUF3560 domain-containing protein -
LCE22_RS23745 (146731) 146731..147294 + 564 WP_029702196.1 class I SAM-dependent methyltransferase -
LCE22_RS23750 (147380) 147380..147556 - 177 Protein_179 pilus protein -
LCE22_RS23755 (147669) 147669..149334 - 1666 Protein_180 group II intron reverse transcriptase/maturase -
LCE22_RS23760 (150995) 150995..151564 - 570 WP_089634947.1 hypothetical protein -
LCE22_RS23770 (152868) 152868..153626 + 759 Protein_183 site-specific integrase -
LCE22_RS23775 (153784) 153784..154794 + 1011 WP_000053332.1 substrate-binding domain-containing protein -
LCE22_RS23780 (154890) 154890..157016 + 2127 WP_000253905.1 alpha-galactosidase -
LCE22_RS23785 (157079) 157079..158040 + 962 Protein_186 oligosaccharide MFS transporter -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance