MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 109135 bp
Accession: NZ_CP082121 Location: 1..109135 Organism: Escherichia coli strain PC-NDM34 Replicon: plasmid pIncFIA
Accession: NZ_CP082121 Location: 1..109135 Organism: Escherichia coli strain PC-NDM34 Replicon: plasmid pIncFIA
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K5P75_RS23455 (1) | 1..978 | + | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| K5P75_RS23460 (1263) | 1263..2003 | - | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| K5P75_RS23465 (2124) | 2124..2306 | - | 183 | WP_042065278.1 | hypothetical protein | - |
| K5P75_RS25530 (2373) | 2373..2662 | - | 290 | Protein_3 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| K5P75_RS23470 (2649) | 2649..2917 | - | 269 | Protein_4 | type II toxin-antitoxin system ParD family antitoxin | - |
| K5P75_RS23475 (3449) | 3449..4618 | + | 1170 | WP_001072355.1 | hypothetical protein | - |
| K5P75_RS23480 (4651) | 4651..4779 | + | 129 | Protein_6 | IS481 family transposase | - |
| K5P75_RS23485 (4814) | 4814..5002 | - | 189 | Protein_7 | hypothetical protein | - |
| K5P75_RS23490 (5050) | 5050..5747 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| K5P75_RS23495 (5938) | 5938..6531 | + | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| K5P75_RS23500 (6644) | 6644..7849 | - | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| K5P75_RS23505 (7931) | 7931..8554 | + | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| K5P75_RS23510 (8532) | 8532..8651 | - | 120 | Protein_12 | transcriptional regulator | - |
| K5P75_RS23520 (9524) | 9524..10078 | - | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| K5P75_RS23525 (10222) | 10222..10926 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| K5P75_RS23530 (10991) | 10991..11671 | - | 681 | Protein_16 | class 1 integron integrase IntI1 | - |
| K5P75_RS23535 (11829) | 11829..12302 | + | 474 | WP_001389366.1 | Dihydrofolate reductase type 1 | ARG |
| K5P75_RS23540 (12433) | 12433..13221 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| K5P75_RS23545 (13427) | 13427..13774 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| K5P75_RS23550 (13768) | 13768..14355 | + | 588 | Protein_20 | dihydropteroate synthase | - |
| K5P75_RS23555 (14421) | 14421..15125 | + | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| K5P75_RS23560 (15254) | 15254..16018 | + | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| K5P75_RS23565 (16511) | 16511..17095 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| K5P75_RS23570 (17095) | 17095..18333 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| K5P75_RS23575 (18330) | 18330..19235 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| K5P75_RS23580 (19357) | 19357..20061 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| K5P75_RS23585 (20220) | 20220..20501 | - | 282 | Protein_27 | transposase zinc-binding domain-containing protein | - |
| K5P75_RS23590 (20648) | 20648..21508 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| K5P75_RS23595 (21691) | 21691..22029 | - | 339 | Protein_29 | Tn3 family transposase TnpR_Tn3 | Transposase |
| K5P75_RS23600 (22093) | 22093..22797 | + | 705 | WP_001067858.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| K5P75_RS23605 (22846) | 22846..23751 | - | 906 | Protein_31 | IS4 family transposase IS10R | Transposase |
| K5P75_RS23610 (23861) | 23861..24823 | - | 963 | Protein_32 | IS4 family transposase IS10R | Transposase |
| K5P75_RS23615 (24966) | 24966..25826 | + | 861 | WP_000557454.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| K5P75_RS23620 (25839) | 25839..26381 | + | 543 | WP_000587837.1 | AAA family ATPase | - |
| K5P75_RS23625 (26863) | 26863..27054 | - | 192 | WP_000951934.1 | hypothetical protein | - |
| K5P75_RS23630 (27078) | 27078..27305 | + | 228 | WP_000248278.1 | hypothetical protein | - |
| K5P75_RS23635 (27356) | 27356..28483 | + | 1128 | WP_014837927.1 | DUF3883 domain-containing protein | - |
| K5P75_RS23640 (28520) | 28520..29224 | + | 705 | WP_213206437.1 | IS6-like element IS26 family transposase | - |
| K5P75_RS23645 (29278) | 29278..29754 | + | 477 | Protein_39 | IS6-like element IS26 family transposase | - |
| K5P75_RS23650 (29804) | 29804..30523 | + | 720 | Protein_40 | helicase RepA family protein | - |
| K5P75_RS23655 (30510) | 30510..31361 | + | 852 | WP_000240536.1 | replication protein C, IncQ-type | - |
| K5P75_RS23660 (31669) | 31669..32484 | + | 816 | WP_001043265.1 | Dihydropteroate synthase | ARG |
| K5P75_RS23665 (32545) | 32545..33348 | + | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| K5P75_RS23670 (33348) | 33348..34184 | + | 837 | WP_000480968.1 | hypothetical protein | ARG |
| K5P75_RS23675 (34245) | 34245..34949 | - | 705 | WP_001067855.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| K5P75_RS23680 (35013) | 35013..35351 | + | 339 | Protein_46 | Tn3 family transposase TnpR_Tn3 | Transposase |
| K5P75_RS23685 (35534) | 35534..36394 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| K5P75_RS23690 (36544) | 36544..36642 | - | 99 | Protein_48 | IS1 family transposase | - |
| K5P75_RS23695 (36671) | 36671..37981 | - | 1311 | WP_001262765.1 | DUF262 domain-containing protein | - |
| K5P75_RS23700 (38266) | 38266..38667 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| K5P75_RS23705 (38600) | 38600..38857 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| K5P75_RS23710 (38950) | 38950..39603 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| K5P75_RS23715 (40542) | 40542..41399 | - | 858 | WP_000130646.1 | incFII family plasmid replication initiator RepA | - |
| K5P75_RS23720 (41392) | 41392..41466 | - | 75 | WP_014966221.1 | RepA leader peptide Tap | - |
| K5P75_RS23725 (41466) | 41466..41597 | - | 132 | Protein_55 | protein CopA/IncA | - |
| K5P75_RS23730 (41828) | 41828..43369 | + | 1542 | WP_002431311.1 | IS21 family transposase ISEc12 | Transposase |
| K5P75_RS23735 (43384) | 43384..44130 | + | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| K5P75_RS23740 (44290) | 44290..44544 | - | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| K5P75_RS23745 (44841) | 44841..44975 | - | 135 | WP_023144756.1 | Hok/Gef family protein | Toxin Detail |
| - (45020) | 45020..45080 | + | 61 | NuclAT_1 | - | Antitoxin Detail |
| - (45020) | 45020..45080 | + | 61 | NuclAT_1 | - | Antitoxin Detail |
| - (45020) | 45020..45080 | + | 61 | NuclAT_1 | - | Antitoxin Detail |
| - (45020) | 45020..45080 | + | 61 | NuclAT_1 | - | Antitoxin Detail |
| K5P75_RS23750 (45047) | 45047..45333 | - | 287 | Protein_60 | DUF2726 domain-containing protein | - |
| K5P75_RS23755 (45846) | 45846..46058 | - | 213 | WP_013023861.1 | hypothetical protein | - |
| K5P75_RS23760 (46189) | 46189..46749 | - | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| K5P75_RS23765 (46804) | 46804..47550 | - | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| K5P75_RS23770 (47570) | 47570..52840 | - | 5271 | WP_001617867.1 | Multifunctional conjugation protein TraI | Relaxase |
| K5P75_RS23775 (52840) | 52840..55074 | - | 2235 | WP_086908463.1 | type IV conjugative transfer system coupling protein TraD | - |
| K5P75_RS23780 (55071) | 55071..55415 | - | 345 | Protein_66 | hypothetical protein | - |
| K5P75_RS23785 (55448) | 55448..56416 | + | 969 | WP_000654811.1 | IS5 family transposase IS903B | Transposase |
| K5P75_RS25535 (56472) | 56472..56915 | - | 444 | Protein_68 | hypothetical protein | - |
| K5P75_RS23795 (57118) | 57118..57849 | - | 732 | WP_000850429.1 | conjugal transfer complement resistance protein TraT | - |
| K5P75_RS23800 (57881) | 57881..58378 | - | 498 | WP_000605862.1 | entry exclusion protein | - |
| K5P75_RS23805 (58397) | 58397..61216 | - | 2820 | WP_001007062.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| K5P75_RS23810 (61213) | 61213..62586 | - | 1374 | WP_000944328.1 | conjugal transfer pilus assembly protein TraH | - |
| K5P75_RS23815 (62573) | 62573..62965 | - | 393 | WP_000659962.1 | F-type conjugal transfer protein TrbF | - |
| K5P75_RS23820 (62946) | 62946..63293 | - | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| K5P75_RS23825 (63223) | 63223..63768 | - | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| K5P75_RS23830 (63755) | 63755..64039 | - | 285 | WP_001617873.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| K5P75_RS23835 (64166) | 64166..64486 | - | 321 | WP_001348757.1 | conjugal transfer protein TrbA | - |
| K5P75_RS23845 (65286) | 65286..65747 | - | 462 | Protein_79 | IS3 family transposase IS150 | Transposase |
| - (65793) | 65793..65895 | - | 103 | NuclAT_0 | - | - |
| - (65793) | 65793..65895 | - | 103 | NuclAT_0 | - | - |
| - (65793) | 65793..65895 | - | 103 | NuclAT_0 | - | - |
| - (65793) | 65793..65895 | - | 103 | NuclAT_0 | - | - |
| K5P75_RS23850 (65864) | 65864..66626 | - | 763 | Protein_80 | plasmid SOS inhibition protein A | - |
| K5P75_RS23855 (66623) | 66623..67057 | - | 435 | WP_000845940.1 | conjugation system SOS inhibitor PsiB | - |
| K5P75_RS23860 (67112) | 67112..69070 | - | 1959 | WP_000117179.1 | ParB/RepB/Spo0J family partition protein | - |
| K5P75_RS23865 (69136) | 69136..69369 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| K5P75_RS23870 (69501) | 69501..69929 | - | 429 | Protein_84 | single-stranded DNA-binding protein | - |
| K5P75_RS23875 (70079) | 70079..71980 | - | 1902 | WP_000936285.1 | group II intron reverse transcriptase/maturase | - |
| K5P75_RS25540 (72658) | 72658..72864 | - | 207 | WP_000547975.1 | hypothetical protein | - |
| K5P75_RS25545 (73105) | 73105..73356 | - | 252 | WP_071579736.1 | hypothetical protein | - |
| K5P75_RS23880 (73275) | 73275..73481 | - | 207 | WP_001774176.1 | hypothetical protein | - |
| K5P75_RS23885 (73507) | 73507..74070 | - | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| K5P75_RS23890 (74118) | 74118..75479 | - | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| K5P75_RS23895 (75531) | 75531..75761 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| K5P75_RS23900 (76796) | 76796..76987 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| K5P75_RS23905 (76984) | 76984..77406 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| K5P75_RS23910 (77453) | 77453..77878 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| K5P75_RS23915 (78295) | 78295..79071 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| K5P75_RS23920 (79122) | 79122..79640 | - | 519 | WP_123325260.1 | DUF1380 family protein | - |
| K5P75_RS23925 (79570) | 79570..79791 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| K5P75_RS23930 (79792) | 79792..80475 | - | 684 | WP_000086185.1 | DNA methylase | - |
| K5P75_RS23935 (80552) | 80552..80863 | - | 312 | WP_011254640.1 | hypothetical protein | - |
| K5P75_RS23940 (80860) | 80860..81762 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| K5P75_RS23945 (82629) | 82629..83600 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| K5P75_RS23950 (83600) | 83600..84766 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| K5P75_RS23955 (85354) | 85354..86109 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| K5P75_RS23960 (86883) | 86883..87689 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| K5P75_RS23965 (87690) | 87690..87995 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| K5P75_RS23970 (87997) | 87997..88215 | - | 219 | WP_023909027.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| K5P75_RS23975 (88849) | 88849..89046 | + | 198 | WP_000215657.1 | hypothetical protein | - |
| K5P75_RS23980 (89043) | 89043..89327 | - | 285 | WP_000642771.1 | hypothetical protein | - |
| K5P75_RS23985 (89347) | 89347..90480 | - | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| K5P75_RS23990 (90743) | 90743..93862 | - | 3120 | WP_023909028.1 | hypothetical protein | - |
| K5P75_RS23995 (94169) | 94169..94399 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| K5P75_RS24000 (94396) | 94396..94812 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| K5P75_RS24005 (94974) | 94974..97112 | - | 2139 | WP_000350635.1 | AAA family ATPase | - |
| K5P75_RS24010 (97577) | 97577..98590 | + | 1014 | WP_085674723.1 | nucleotidyltransferase | - |
| K5P75_RS24015 (98594) | 98594..99526 | + | 933 | WP_000991832.1 | S-4TM family putative pore-forming effector | - |
| K5P75_RS24025 (100574) | 100574..103690 | - | 3117 | WP_031311986.1 | HsdR family type I site-specific deoxyribonuclease | - |
| K5P75_RS24030 (103812) | 103812..105095 | - | 1284 | WP_001617890.1 | restriction endonuclease subunit S | - |
| K5P75_RS24035 (105092) | 105092..106648 | - | 1557 | WP_001553856.1 | type I restriction-modification system subunit M | - |
| K5P75_RS24040 (106831) | 106831..107052 | + | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| K5P75_RS24045 (107052) | 107052..107432 | + | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | - |
| K5P75_RS24050 (107437) | 107437..107616 | + | 180 | WP_001513661.1 | hypothetical protein | - |
| K5P75_RS24055 (107644) | 107644..107922 | + | 279 | Protein_123 | pdcB | - |
| K5P75_RS24060 (107927) | 107927..108340 | + | 414 | Protein_124 | integrase core domain-containing protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|