MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 157909 bp
Accession: NZ_CP082032 Location: 5058728..5216636 Organism: Klebsiella pneumoniae strain KP18-2138 Replicon: chromosome
Accession: NZ_CP082032 Location: 5058728..5216636 Organism: Klebsiella pneumoniae strain KP18-2138 Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K6163_RS25010 | 5053729..5055525 | + | 1797 | WP_004152424.1 | protein-disulfide reductase DsbD | - |
| K6163_RS25015 | 5055546..5056136 | + | 591 | WP_002885410.1 | transcriptional regulator | - |
| K6163_RS25020 | 5056204..5058291 | + | 2088 | WP_002885407.1 | DUF1176 domain-containing protein | - |
| K6163_RS25030 | 5059074..5059364 | - | 291 | WP_004153693.1 | PerC family transcriptional regulator | - |
| K6163_RS25035 | 5059559..5059681 | + | 123 | WP_004229880.1 | hypothetical protein | - |
| K6163_RS25040 | 5059676..5060242 | - | 567 | WP_002885396.1 | hypothetical protein | VF |
| K6163_RS25045 | 5060876..5063323 | + | 2448 | WP_014342860.1 | poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA | - |
| K6163_RS25050 | 5063332..5065347 | + | 2016 | WP_002885394.1 | hypothetical protein | VF |
| K6163_RS25055 | 5065340..5066668 | + | 1329 | WP_002885393.1 | hypothetical protein | VF |
| K6163_RS25060 | 5066668..5067117 | + | 450 | WP_002885392.1 | poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD | - |
| K6163_RS25065 | 5067163..5067948 | - | 786 | WP_002885391.1 | DsbA family protein | - |
| K6163_RS25070 | 5068174..5068857 | + | 684 | WP_004199298.1 | TerC family protein | - |
| K6163_RS25075 | 5068814..5068927 | - | 114 | WP_002885341.1 | hypothetical protein | - |
| K6163_RS25080 | 5069003..5069920 | + | 918 | WP_002885338.1 | curved DNA-binding protein | - |
| K6163_RS25085 | 5069920..5070225 | + | 306 | WP_002885324.1 | chaperone modulator CbpM | - |
| K6163_RS25090 | 5070394..5070819 | + | 426 | Protein_4936 | IS3 family transposase | - |
| K6163_RS25095 | 5070884..5071588 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6163_RS25100 | 5072119..5072349 | + | 231 | WP_004213073.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| K6163_RS25105 | 5072346..5072789 | + | 444 | WP_004213072.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| K6163_RS28990 | 5072938..5073189 | + | 252 | WP_186987481.1 | IS3 family transposase ISEc16 | Transposase |
| K6163_RS25115 | 5073212..5073516 | - | 305 | Protein_4941 | IS3 family transposase ISEc16 | Transposase |
| K6163_RS25120 | 5073933..5074567 | + | 635 | Protein_4942 | hypothetical protein | VF |
| K6163_RS25125 | 5075085..5075488 | - | 404 | Protein_4943 | GAF domain-containing protein | - |
| K6163_RS25130 | 5075579..5076499 | - | 921 | WP_004213934.1 | DUF1471 domain-containing protein | - |
| K6163_RS25135 | 5076548..5077039 | - | 492 | WP_011251327.1 | DM13 domain-containing protein | - |
| K6163_RS25140 | 5077102..5077368 | - | 267 | WP_147021650.1 | carboxymuconolactone decarboxylase family protein | - |
| K6163_RS25145 | 5077461..5077889 | - | 429 | WP_004902152.1 | DUF417 family protein | - |
| K6163_RS25150 | 5077927..5078487 | - | 561 | WP_004213927.1 | TetR/AcrR family transcriptional regulator | - |
| K6163_RS25155 | 5078529..5078789 | - | 261 | WP_004213925.1 | DUF1471 domain-containing protein | - |
| K6163_RS25160 | 5079456..5081657 | - | 2202 | WP_004213924.1 | hypothetical protein | VF |
| K6163_RS25165 | 5081683..5083016 | - | 1334 | Protein_4951 | hypothetical protein | VF |
| K6163_RS25170 | 5083020..5084753 | - | 1734 | WP_004213922.1 | hypothetical protein | VF |
| K6163_RS25175 | 5084753..5085700 | - | 948 | WP_004213921.1 | hypothetical protein | VF |
| K6163_RS25180 | 5085701..5087425 | - | 1725 | WP_004213920.1 | hypothetical protein | VF |
| K6163_RS25185 | 5087582..5088781 | + | 1200 | WP_088476450.1 | MFS transporter | - |
| K6163_RS25190 | 5088834..5089073 | + | 240 | WP_004145299.1 | hypothetical protein | - |
| K6163_RS25195 | 5089509..5089673 | + | 165 | WP_223174999.1 | hypothetical protein | - |
| K6163_RS25200 | 5089809..5090296 | + | 488 | Protein_4958 | IS630 family transposase IS630 | Transposase |
| K6163_RS25205 | 5090534..5091043 | + | 510 | WP_004145290.1 | peptide deformylase | - |
| K6163_RS25210 | 5091093..5091242 | + | 150 | Protein_4960 | iron dicitrate transport regulator FecR | - |
| K6163_RS25215 | 5091593..5091910 | - | 318 | WP_004213915.1 | c-type lysozyme inhibitor | - |
| K6163_RS25220 | 5092147..5092533 | - | 387 | WP_004902159.1 | hypothetical protein | - |
| K6163_RS25225 | 5092631..5093830 | + | 1200 | WP_101992397.1 | GTP-binding protein | - |
| K6163_RS25230 | 5093901..5094323 | + | 423 | WP_004214547.1 | RNA polymerase-binding protein DksA | - |
| K6163_RS25235 | 5094387..5095322 | + | 936 | WP_011251270.1 | GTP cyclohydrolase FolE2 | - |
| K6163_RS25240 | 5095312..5095872 | + | 561 | WP_004214543.1 | carbonate dehydratase | - |
| K6163_RS25245 | 5096002..5096868 | + | 867 | WP_011251271.1 | hypothetical protein | - |
| K6163_RS25250 | 5096885..5097709 | - | 825 | WP_004214540.1 | DUF1460 domain-containing protein | - |
| K6163_RS25255 | 5098139..5099140 | + | 1002 | WP_011251272.1 | threonine--tRNA ligase | - |
| K6163_RS25260 | 5099133..5099984 | + | 852 | WP_004214538.1 | M14 family metallocarboxypeptidase | - |
| K6163_RS25265 | 5099981..5101327 | + | 1347 | WP_011154555.1 | dihydroorotase | - |
| K6163_RS25270 | 5101391..5102413 | + | 1023 | WP_101992398.1 | porphobilinogen synthase | - |
| K6163_RS25275 | 5102588..5102983 | + | 396 | Protein_4973 | IS3 family transposase | - |
| K6163_RS25280 | 5102979..5104206 | - | 1228 | Protein_4974 | IS3 family transposase | - |
| K6163_RS25285 | 5104645..5105277 | + | 633 | WP_001567369.1 | hypothetical protein | - |
| K6163_RS25290 | 5105306..5106709 | - | 1404 | WP_001567368.1 | ISNCY family transposase ISKpn21 | Transposase |
| K6163_RS25295 | 5106902..5108389 | - | 1488 | WP_023332914.1 | hypothetical protein | VF |
| K6163_RS25300 | 5108825..5109139 | + | 315 | WP_004196316.1 | hypothetical protein | - |
| K6163_RS25305 | 5109148..5109657 | + | 510 | WP_004181938.1 | hypothetical protein | - |
| K6163_RS25310 | 5109647..5110087 | + | 441 | WP_074404002.1 | hypothetical protein | - |
| K6163_RS25315 | 5110117..5110773 | + | 657 | WP_101992399.1 | hypothetical protein | - |
| K6163_RS25320 | 5111047..5111649 | - | 603 | WP_004181934.1 | HAD domain-containing protein | - |
| K6163_RS25325 | 5111652..5112167 | - | 516 | WP_004196349.1 | hypothetical protein | - |
| K6163_RS28995 | 5112772..5113242 | - | 471 | WP_224146629.1 | hypothetical protein | - |
| K6163_RS25335 | 5113472..5114428 | - | 957 | WP_004196319.1 | DsbA family protein | - |
| K6163_RS25340 | 5114488..5114829 | - | 342 | WP_004181929.1 | hypothetical protein | - |
| K6163_RS25345 | 5114843..5115154 | - | 312 | WP_004181928.1 | hypothetical protein | - |
| K6163_RS25350 | 5115171..5115899 | - | 729 | WP_004181926.1 | thioredoxin fold domain-containing protein | - |
| K6163_RS25355 | 5116033..5116647 | + | 615 | WP_004026303.1 | hypothetical protein | VF |
| K6163_RS25360 | 5116915..5118198 | - | 1284 | WP_223819051.1 | DEAD/DEAH box helicase | - |
| K6163_RS25370 | 5119484..5121061 | - | 1578 | WP_224146627.1 | AAA domain-containing protein | - |
| K6163_RS25375 | 5121084..5121440 | - | 357 | WP_004196338.1 | hypothetical protein | - |
| K6163_RS25380 | 5122329..5122634 | + | 306 | WP_004181922.1 | hypothetical protein | - |
| K6163_RS25385 | 5122685..5126653 | - | 3969 | WP_004196345.1 | conjugal transfer protein TraG N-terminal domain-containing protein | - |
| K6163_RS25390 | 5126655..5127650 | - | 996 | WP_250947865.1 | conjugal transfer protein TraH | - |
| K6163_RS25400 | 5128476..5128787 | - | 312 | Protein_4998 | conjugal transfer protein TraH | - |
| K6163_RS25405 | 5128831..5129868 | - | 1038 | WP_004196361.1 | conjugal transfer protein TraF | - |
| K6163_RS25410 | 5130234..5130776 | - | 543 | WP_004196331.1 | hypothetical protein | - |
| K6163_RS25415 | 5130793..5131317 | - | 525 | WP_032438005.1 | hypothetical protein | - |
| K6163_RS25420 | 5131510..5132265 | - | 756 | WP_004196341.1 | hypothetical protein | - |
| K6163_RS25425 | 5132863..5133327 | + | 465 | WP_004026319.1 | conjugative transfer protein MobI(A/C) | - |
| K6163_RS25430 | 5133327..5134115 | + | 789 | WP_004196318.1 | hypothetical protein | - |
| K6163_RS25435 | 5134129..5137077 | + | 2949 | WP_032438004.1 | MobH family relaxase | - |
| K6163_RS25440 | 5137067..5139193 | + | 2127 | WP_032438003.1 | conjugative transfer system coupling protein TraD | - |
| K6163_RS25445 | 5139196..5140293 | + | 1098 | WP_004181912.1 | hypothetical protein | - |
| K6163_RS25450 | 5140306..5140980 | + | 675 | WP_004181910.1 | DUF4400 domain-containing protein | - |
| K6163_RS25455 | 5140989..5142125 | + | 1137 | WP_004181908.1 | S49 family peptidase | - |
| K6163_RS25460 | 5142128..5142901 | + | 774 | WP_004181907.1 | nuclease-related domain-containing protein | - |
| K6163_RS25465 | 5142955..5143233 | - | 279 | WP_065366041.1 | hypothetical protein | - |
| K6163_RS25470 | 5143854..5144087 | - | 234 | WP_004181905.1 | hypothetical protein | - |
| K6163_RS25475 | 5144166..5144513 | - | 348 | WP_004181904.1 | hypothetical protein | - |
| K6163_RS25480 | 5144669..5145736 | - | 1068 | WP_004181903.1 | hypothetical protein | - |
| K6163_RS25485 | 5146426..5146803 | + | 378 | WP_004181901.1 | hypothetical protein | - |
| K6163_RS25490 | 5147001..5147975 | - | 975 | WP_004181899.1 | hypothetical protein | - |
| K6163_RS25495 | 5148578..5148736 | - | 159 | WP_004181898.1 | type I toxin-antitoxin system Hok family toxin | - |
| K6163_RS25500 | 5148808..5149095 | - | 288 | WP_000323025.1 | type II toxin-antitoxin system mRNA interferase RelE | Toxin Detail |
| K6163_RS25505 | 5149095..5149334 | - | 240 | WP_000534858.1 | type II toxin-antitoxin system antitoxin RelB | Antitoxin Detail |
| K6163_RS29000 | 5149359..5149463 | + | 105 | Protein_5020 | hypothetical protein | - |
| K6163_RS25510 | 5149597..5149920 | - | 324 | WP_224948387.1 | cation transporter dimerization domain-containing protein | - |
| K6163_RS25515 | 5150086..5151254 | + | 1169 | WP_085929673.1 | IS3 family transposase ISLad1 | Transposase |
| K6163_RS25520 | 5151264..5151575 | - | 312 | Protein_5023 | IS110 family transposase ISCps4 | Transposase |
| K6163_RS25525 | 5151996..5153336 | - | 1341 | WP_000589001.1 | ISNCY family transposase ISCARN112 | Transposase |
| K6163_RS25530 | 5153568..5154272 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6163_RS25535 | 5154323..5154883 | + | 561 | WP_021532377.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| K6163_RS25540 | 5154886..5157357 | + | 2472 | Protein_5027 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| K6163_RS25545 | 5157504..5158364 | - | 861 | WP_000027057.1 | hypothetical protein | ARG |
| K6163_RS25550 | 5158547..5159104 | - | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| K6163_RS25555 | 5159268..5159486 | + | 219 | WP_001143771.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| K6163_RS25560 | 5159668..5160930 | + | 1263 | WP_000608644.1 | IS1380 family transposase ISEcp1 | Transposase |
| K6163_RS25565 | 5161186..5162061 | + | 876 | WP_000239590.1 | hypothetical protein | ARG |
| K6163_RS25570 | 5162108..5162452 | - | 345 | Protein_5033 | WbuC family cupin fold metalloprotein | - |
| K6163_RS25575 | 5162466..5164685 | + | 2220 | Protein_5034 | Tn3 family transposase TnpA_Tn3 | Transposase |
| K6163_RS25580 | 5164762..5165466 | + | 705 | WP_004217321.1 | IS6 family transposase IS26 | Transposase |
| K6163_RS25585 | 5165610..5166164 | + | 555 | WP_063840321.1 | hypothetical protein | ARG |
| K6163_RS25590 | 5166295..5167125 | + | 831 | WP_001334766.1 | hypothetical protein | ARG |
| K6163_RS25595 | 5167263..5167703 | + | 441 | Protein_5038 | CatB-related O-acetyltransferase | - |
| K6163_RS25600 | 5167757..5168461 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6163_RS25605 | 5168527..5170041 | + | 1515 | Protein_5040 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| K6163_RS25610 | 5170083..5170325 | + | 243 | WP_032140899.1 | hypothetical protein | - |
| K6163_RS25615 | 5170357..5171007 | - | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| K6163_RS25620 | 5171113..5172312 | + | 1200 | WP_000804064.1 | hypothetical protein | ARG |
| K6163_RS25625 | 5172344..5173228 | - | 885 | WP_000058717.1 | EamA family transporter | - |
| K6163_RS25630 | 5173366..5173758 | - | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| K6163_RS25635 | 5173762..5174511 | + | 750 | Protein_5046 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| K6163_RS25640 | 5174535..5175083 | - | 549 | WP_050497034.1 | recombinase family protein | - |
| K6163_RS25645 | 5175089..5175793 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6163_RS25650 | 5175944..5176759 | + | 816 | WP_000018329.1 | hypothetical protein | ARG |
| K6163_RS25655 | 5176949..5177617 | - | 669 | WP_044117068.1 | IS6 family transposase IS26 | Transposase |
| K6163_RS25660 | 5177909..5178913 | - | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| K6163_RS25665 | 5178992..5180164 | - | 1173 | Protein_5052 | Tn3 family transposase TnpA_ISSba14 | Transposase |
| K6163_RS25670 | 5180248..5180952 | + | 705 | WP_004217321.1 | IS6 family transposase IS26 | Transposase |
| K6163_RS25675 | 5181007..5181342 | - | 336 | Protein_5054 | class II aldolase/adducin family protein | - |
| K6163_RS25680 | 5181335..5182587 | - | 1253 | Protein_5055 | four-carbon acid sugar kinase family protein | - |
| K6163_RS25685 | 5182599..5183501 | - | 903 | WP_002903955.1 | NAD(P)-dependent oxidoreductase | - |
| K6163_RS25690 | 5183763..5184524 | + | 762 | WP_002210513.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| K6163_RS25695 | 5184545..5185405 | - | 861 | WP_004176269.1 | hypothetical protein | ARG |
| K6163_RS25700 | 5185542..5186246 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6163_RS25705 | 5186297..5187243 | + | 947 | Protein_5060 | IS3 family transposase ISKpn1 | Transposase |
| K6163_RS25710 | 5187409..5187780 | - | 372 | WP_004151723.1 | plasmid partitioning/stability family protein | - |
| K6163_RS25715 | 5187790..5188746 | - | 957 | WP_004146678.1 | plasmid segregation protein ParM | - |
| K6163_RS25720 | 5188894..5189016 | - | 123 | WP_004218082.1 | hypothetical protein | - |
| K6163_RS25725 | 5189022..5190437 | - | 1416 | WP_004218080.1 | melibiose:sodium transporter MelB | - |
| K6163_RS25730 | 5190531..5191883 | - | 1353 | WP_004198385.1 | alpha-glucosidase/alpha-galactosidase | - |
| K6163_RS25735 | 5192123..5193061 | + | 939 | WP_002885229.1 | transcriptional regulator MelR | - |
| K6163_RS25740 | 5193111..5194613 | - | 1503 | WP_002885227.1 | glycine betaine/L-proline transporter ProP | - |
| K6163_RS25745 | 5195158..5195493 | + | 336 | WP_002885223.1 | zinc ribbon domain-containing protein YjdM | - |
| K6163_RS25750 | 5195722..5196156 | + | 435 | WP_002885221.1 | VOC family metalloprotein YjdN | - |
| K6163_RS25755 | 5196312..5197037 | + | 726 | WP_002885217.1 | phosphonate metabolism transcriptional regulator PhnF | - |
| K6163_RS25760 | 5197038..5197490 | + | 453 | WP_002885214.1 | phosphonate C-P lyase system protein PhnG | - |
| K6163_RS25765 | 5197487..5198071 | + | 585 | WP_002885207.1 | phosphonate C-P lyase system protein PhnH | - |
| K6163_RS25770 | 5198072..5199136 | + | 1065 | WP_002885205.1 | carbon-phosphorus lyase complex subunit PhnI | - |
| K6163_RS25775 | 5199129..5199977 | + | 849 | WP_002885202.1 | alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase PhnJ | - |
| K6163_RS25780 | 5199974..5200732 | + | 759 | WP_002885198.1 | phosphonate C-P lyase system protein PhnK | - |
| K6163_RS25785 | 5200840..5201520 | + | 681 | WP_002885196.1 | hypothetical protein | VF |
| K6163_RS25790 | 5201517..5202653 | + | 1137 | WP_004151726.1 | alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase | - |
| K6163_RS25795 | 5202653..5203216 | + | 564 | WP_004151727.1 | ribose 1,5-bisphosphokinase | - |
| K6163_RS25800 | 5203232..5203990 | + | 759 | WP_004151728.1 | phosphonate metabolism protein PhnP | - |
| K6163_RS25805 | 5204012..5204365 | - | 354 | WP_004151729.1 | DDRRRQL repeat protein YjdP | - |
| K6163_RS25810 | 5204436..5206721 | - | 2286 | WP_004151730.1 | hypothetical protein | VF |
| K6163_RS25815 | 5206901..5208421 | + | 1521 | WP_002885173.1 | hypothetical protein | VF |
| K6163_RS25820 | 5208418..5209416 | + | 999 | WP_002885172.1 | ribose ABC transporter permease | - |
| K6163_RS25825 | 5209447..5210388 | + | 942 | WP_002885156.1 | ABC transporter substrate-binding protein | - |
| K6163_RS25830 | 5210463..5211470 | + | 1008 | WP_004151731.1 | carbohydrate kinase family protein | - |
| K6163_RS25835 | 5211595..5212512 | - | 918 | WP_002885155.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin Detail |
| K6163_RS25840 | 5212518..5213276 | - | 759 | WP_004151732.1 | type IV toxin-antitoxin system AbiEi family antitoxin | Antitoxin Detail |
| K6163_RS25845 | 5213362..5214090 | - | 729 | WP_002885152.1 | hypothetical protein | VF |
| K6163_RS25850 | 5214363..5216510 | + | 2148 | WP_077598858.1 | formate dehydrogenase subunit alpha | - |
| K6163_RS25855 | 5216740..5217426 | + | 687 | WP_004151733.1 | tetratricopeptide repeat protein | - |
| K6163_RS25860 | 5217463..5218776 | - | 1314 | WP_004146659.1 | glutamate/aspartate:proton symporter GltP | - |
| K6163_RS25865 | 5218888..5219088 | - | 201 | WP_004226113.1 | hypothetical protein | - |
| K6163_RS25870 | 5219189..5221147 | + | 1959 | WP_002885145.1 | acetate--CoA ligase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|