MGE detailed information
MGE type: Conjugative plasmid MGE length: 105913 bp
Accession: NZ_CP082004 Location: 1..105913 Organism: Klebsiella pneumoniae strain KP18-8 Replicon: plasmid pKP18-8-KPC2
Accession: NZ_CP082004 Location: 1..105913 Organism: Klebsiella pneumoniae strain KP18-8 Replicon: plasmid pKP18-8-KPC2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K6148_RS00005 (19) | 19..894 | + | 876 | WP_004098982.1 | replication initiation protein | - |
| K6148_RS00010 (1551) | 1551..2177 | + | 627 | WP_004197649.1 | Chromosome-partitioning ATPase Soj | VF |
| K6148_RS28385 (2174) | 2174..2476 | + | 303 | WP_004197636.1 | hypothetical protein | - |
| K6148_RS00020 (2940) | 2940..3734 | - | 795 | WP_004197635.1 | site-specific integrase | - |
| K6148_RS00025 (3932) | 3932..4948 | - | 1017 | WP_017899884.1 | hypothetical protein | - |
| K6148_RS00030 (4959) | 4959..5273 | - | 315 | WP_053389906.1 | hypothetical protein | - |
| K6148_RS00035 (5300) | 5300..5695 | - | 396 | WP_017899885.1 | hypothetical protein | - |
| K6148_RS00040 (5864) | 5864..6169 | - | 306 | WP_013023785.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| K6148_RS00045 (6171) | 6171..6389 | - | 219 | WP_001568025.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| K6148_RS00050 (6559) | 6559..7020 | - | 462 | WP_160880186.1 | hypothetical protein | - |
| K6148_RS00055 (6977) | 6977..7207 | + | 231 | WP_001261282.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| K6148_RS00060 (7204) | 7204..7620 | + | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| K6148_RS00065 (7694) | 7694..9256 | + | 1563 | WP_004206609.1 | AAA family ATPase | - |
| K6148_RS00070 (9241) | 9241..10263 | + | 1023 | WP_000361404.1 | helicase UvrD | - |
| K6148_RS00075 (10519) | 10519..11216 | + | 698 | WP_223174630.1 | IS1 family transposase ISKpn14 | Transposase |
| K6148_RS00080 (11245) | 11245..11517 | + | 273 | Protein_15 | IS5 family transposase ISPan1 | Transposase |
| K6148_RS00085 (11797) | 11797..12799 | - | 1003 | Protein_16 | IS110 family transposase IS4321 | Transposase |
| K6148_RS00090 (12878) | 12878..13312 | - | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| K6148_RS00095 (13384) | 13384..13734 | + | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| K6148_RS00100 (13748) | 13748..14023 | + | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| K6148_RS00105 (14059) | 14059..14481 | + | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| K6148_RS00110 (14533) | 14533..16227 | + | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| K6148_RS00115 (16245) | 16245..16607 | + | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| K6148_RS00120 (16604) | 16604..16840 | + | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| K6148_RS00125 (16876) | 16876..17544 | + | 669 | WP_001300294.1 | putative signaling protein | VF |
| K6148_RS00130 (17619) | 17619..18869 | + | 1251 | Protein_25 | transposase | - |
| K6148_RS00135 (18934) | 18934..19638 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6148_RS00140 (19693) | 19693..20271 | + | 579 | Protein_27 | replication protein | - |
| K6148_RS00145 (20805) | 20805..21083 | + | 279 | WP_013213990.1 | hypothetical protein | - |
| K6148_RS00150 (21194) | 21194..21619 | + | 426 | WP_013213989.1 | antirestriction protein | - |
| K6148_RS00155 (21747) | 21747..21902 | + | 156 | WP_013213988.1 | hypothetical protein | - |
| K6148_RS00160 (21948) | 21948..22244 | + | 297 | WP_013213987.1 | transcriptional regulator | - |
| K6148_RS00165 (22348) | 22348..23229 | + | 882 | Protein_32 | IS1182 family transposase ISKpn6 | Transposase |
| K6148_RS00170 (23479) | 23479..24360 | - | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| K6148_RS00175 (24636) | 24636..25616 | - | 981 | WP_013213985.1 | IS481 family transposase ISKpn27 | Transposase |
| K6148_RS00180 (25739) | 25739..26200 | - | 462 | Protein_35 | Tn3 family transposase TnpR_Tn3 | Transposase |
| K6148_RS00185 (26252) | 26252..26956 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| K6148_RS00190 (27456) | 27456..28016 | + | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| K6148_RS00195 (28020) | 28020..30986 | + | 2967 | WP_001517980.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| K6148_RS00200 (31020) | 31020..31322 | + | 303 | Protein_39 | IS6 family transposase IS26 | Transposase |
| K6148_RS00205 (31524) | 31524..31997 | - | 474 | WP_013213991.1 | GNAT family N-acetyltransferase | - |
| K6148_RS00210 (32417) | 32417..32929 | - | 513 | Protein_41 | ISL3 family transposase ISEc38 | Transposase |
| K6148_RS00215 (32933) | 32933..33265 | - | 333 | WP_013213994.1 | hypothetical protein | - |
| K6148_RS00220 (33651) | 33651..34562 | - | 912 | WP_013213995.1 | hypothetical protein | - |
| K6148_RS00225 (34614) | 34614..36556 | - | 1943 | Protein_44 | hypothetical protein | - |
| K6148_RS00230 (36560) | 36560..37453 | - | 894 | WP_013213999.1 | hypothetical protein | - |
| K6148_RS00235 (37461) | 37461..38702 | - | 1242 | WP_013213998.1 | N-6 DNA methylase | - |
| K6148_RS00240 (40022) | 40022..40897 | - | 876 | WP_072101968.1 | incFII family plasmid replication initiator RepA | - |
| K6148_RS00250 (41195) | 41195..41452 | - | 258 | WP_015344940.1 | replication regulatory protein RepA | - |
| K6148_RS00255 (41584) | 41584..42135 | - | 552 | WP_015344941.1 | Phospholipase D | VF |
| K6148_RS00260 (42239) | 42239..42547 | - | 309 | WP_004152383.1 | hypothetical protein | - |
| K6148_RS00265 (42544) | 42544..43194 | - | 651 | WP_014343480.1 | DUF2726 domain-containing protein | - |
| K6148_RS00270 (43250) | 43250..43894 | - | 645 | WP_004153014.1 | hypothetical protein | - |
| K6148_RS00275 (43944) | 43944..44546 | - | 603 | WP_013023836.1 | PIN domain-containing protein | - |
| K6148_RS00280 (44707) | 44707..45300 | - | 594 | WP_015344942.1 | fertility inhibition protein FinO | - |
| K6148_RS00285 (45372) | 45372..46097 | - | 726 | WP_015344943.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| K6148_RS00290 (46141) | 46141..51402 | - | 5262 | WP_064291677.1 | Multifunctional conjugation protein TraI | Relaxase |
| K6148_RS00295 (51402) | 51402..53714 | - | 2313 | WP_072101984.1 | type IV conjugative transfer system coupling protein TraD | - |
| K6148_RS00300 (53843) | 53843..54532 | - | 690 | WP_072101983.1 | hypothetical protein | - |
| K6148_RS00305 (54725) | 54725..55456 | - | 732 | WP_004152629.1 | conjugal transfer complement resistance protein TraT | - |
| K6148_RS00310 (55642) | 55642..56175 | - | 534 | WP_014343486.1 | conjugal transfer protein TraS | - |
| K6148_RS00315 (56178) | 56178..59027 | - | 2850 | WP_013609534.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| K6148_RS00320 (59027) | 59027..60406 | - | 1380 | WP_014343487.1 | conjugal transfer pilus assembly protein TraH | - |
| K6148_RS00325 (60384) | 60384..60827 | - | 444 | WP_004194305.1 | F-type conjugal transfer protein TrbF | - |
| K6148_RS00330 (60873) | 60873..61430 | - | 558 | WP_013214031.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| K6148_RS00335 (61402) | 61402..61641 | - | 240 | WP_004144400.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| K6148_RS00340 (61652) | 61652..62404 | - | 753 | WP_004152677.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| K6148_RS00345 (62425) | 62425..62751 | - | 327 | WP_004152676.1 | hypothetical protein | - |
| K6148_RS00350 (62764) | 62764..63012 | - | 249 | WP_004152675.1 | hypothetical protein | - |
| K6148_RS00355 (62990) | 62990..63244 | - | 255 | WP_004152674.1 | conjugal transfer protein TrbE | - |
| K6148_RS00360 (63276) | 63276..65231 | - | 1956 | WP_030003482.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| K6148_RS00365 (65290) | 65290..65928 | - | 639 | WP_069985712.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| K6148_RS00370 (65941) | 65941..66930 | - | 990 | WP_029497420.1 | conjugal transfer pilus assembly protein TraU | - |
| K6148_RS00375 (66927) | 66927..67328 | - | 402 | WP_004194979.1 | hypothetical protein | - |
| K6148_RS00380 (67363) | 67363..67998 | - | 636 | WP_029497419.1 | type-F conjugative transfer system protein TraW | - |
| K6148_RS00385 (67998) | 67998..68387 | - | 390 | WP_004167468.1 | type-F conjugative transfer system protein TrbI | - |
| K6148_RS00390 (68387) | 68387..71026 | - | 2640 | WP_013214024.1 | type IV secretion system protein TraC | - |
| K6148_RS00395 (71098) | 71098..71496 | - | 399 | WP_023179972.1 | hypothetical protein | - |
| K6148_RS00400 (71875) | 71875..72279 | - | 405 | WP_004197817.1 | hypothetical protein | - |
| K6148_RS00405 (72346) | 72346..72657 | - | 312 | WP_094965623.1 | hypothetical protein | - |
| K6148_RS00410 (72658) | 72658..72876 | - | 219 | WP_004195468.1 | hypothetical protein | - |
| K6148_RS00415 (73199) | 73199..73783 | - | 585 | WP_032440547.1 | type IV conjugative transfer system lipoprotein TraV | - |
| K6148_RS00420 (73856) | 73856..75280 | - | 1425 | WP_004194260.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| K6148_RS00425 (75280) | 75280..76020 | - | 741 | WP_013023821.1 | type-F conjugative transfer system secretin TraK | - |
| K6148_RS00430 (76007) | 76007..76573 | - | 567 | WP_004144423.1 | type IV conjugative transfer system protein TraE | - |
| K6148_RS00435 (76593) | 76593..76898 | - | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| K6148_RS00440 (76912) | 76912..77280 | - | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| K6148_RS00445 (77349) | 77349..77549 | - | 201 | WP_004194116.1 | TraY domain-containing protein | - |
| K6148_RS00450 (77635) | 77635..78336 | - | 702 | WP_004194113.1 | hypothetical protein | - |
| K6148_RS00455 (78566) | 78566..78958 | - | 393 | WP_004194114.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| K6148_RS00460 (79390) | 79390..79875 | + | 486 | WP_032440470.1 | hypothetical protein | VF |
| K6148_RS00465 (79908) | 79908..80237 | - | 330 | WP_071994324.1 | DUF5983 family protein | - |
| K6148_RS00470 (80270) | 80270..81091 | - | 822 | WP_023287138.1 | DUF932 domain-containing protein | - |
| K6148_RS00475 (81921) | 81921..82334 | - | 414 | WP_069985713.1 | helix-turn-helix domain-containing protein | - |
| K6148_RS00480 (82335) | 82335..82613 | - | 279 | WP_004152721.1 | helix-turn-helix transcriptional regulator | - |
| K6148_RS00485 (82603) | 82603..82923 | - | 321 | WP_004152720.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| K6148_RS00490 (83004) | 83004..83228 | - | 225 | WP_014343499.1 | hypothetical protein | - |
| K6148_RS00495 (83239) | 83239..83451 | - | 213 | WP_019706020.1 | hypothetical protein | - |
| K6148_RS00500 (83512) | 83512..83868 | - | 357 | WP_019706019.1 | hypothetical protein | - |
| K6148_RS00505 (84500) | 84500..84850 | - | 351 | WP_023287104.1 | hypothetical protein | - |
| K6148_RS00510 (84847) | 84847..85119 | - | 273 | WP_023287105.1 | hypothetical protein | - |
| K6148_RS00515 (85812) | 85812..85910 | - | 99 | WP_159224797.1 | Hok/Gef family protein | - |
| K6148_RS28575 (85885) | 85885..85941 | - | 57 | Protein_102 | modulator protein | - |
| K6148_RS00520 (86040) | 86040..87113 | + | 1074 | WP_048270288.1 | IS481 family transposase ISKpn28 | Transposase |
| - (87113) | 87113..87237 | - | 125 | NuclAT_0 | - | - |
| - (87113) | 87113..87237 | - | 125 | NuclAT_0 | - | - |
| - (87113) | 87113..87237 | - | 125 | NuclAT_0 | - | - |
| - (87113) | 87113..87237 | - | 125 | NuclAT_0 | - | - |
| K6148_RS00525 (87297) | 87297..87671 | - | 375 | WP_023287106.1 | hypothetical protein | - |
| K6148_RS00530 (87727) | 87727..88053 | - | 327 | WP_001568059.1 | hypothetical protein | - |
| K6148_RS00535 (88050) | 88050..88778 | - | 729 | WP_040194708.1 | plasmid SOS inhibition protein A | - |
| K6148_RS00540 (88775) | 88775..89206 | - | 432 | WP_001568057.1 | conjugation system SOS inhibitor PsiB | - |
| K6148_RS00545 (89251) | 89251..91308 | - | 2058 | WP_069335038.1 | ParB/RepB/Spo0J family partition protein | - |
| K6148_RS00550 (91378) | 91378..91626 | - | 249 | WP_009310026.1 | DUF905 domain-containing protein | - |
| K6148_RS00555 (91675) | 91675..92217 | - | 543 | WP_015065513.1 | single-stranded DNA-binding protein | - |
| K6148_RS00560 (93048) | 93048..93611 | - | 564 | WP_004152756.1 | methyltransferase | - |
| K6148_RS00565 (93659) | 93659..95014 | - | 1356 | WP_032418010.1 | DUF3560 domain-containing protein | - |
| K6148_RS00570 (95066) | 95066..95296 | - | 231 | WP_001568051.1 | hypothetical protein | - |
| K6148_RS00575 (95388) | 95388..95615 | - | 228 | WP_001568050.1 | hypothetical protein | - |
| K6148_RS00580 (96348) | 96348..96668 | - | 321 | WP_032436760.1 | hypothetical protein | - |
| K6148_RS00585 (96703) | 96703..96957 | - | 255 | WP_011977779.1 | DNA polymerase III subunit theta | - |
| K6148_RS00590 (97145) | 97145..97336 | - | 192 | WP_001568047.1 | hypothetical protein | - |
| K6148_RS00595 (97379) | 97379..97885 | - | 507 | WP_013214014.1 | antirestriction protein ArdA | - |
| K6148_RS00600 (97928) | 97928..98356 | - | 429 | WP_001568045.1 | antirestriction protein | - |
| K6148_RS00605 (99037) | 99037..99804 | - | 768 | WP_013214013.1 | hypothetical protein | - |
| K6148_RS00610 (99858) | 99858..100277 | - | 420 | WP_001568043.1 | DUF1380 domain-containing protein | - |
| K6148_RS00615 (100287) | 100287..100508 | - | 222 | WP_001568042.1 | hypothetical protein | - |
| K6148_RS00620 (100508) | 100508..101209 | - | 702 | WP_001568041.1 | DNA methylase | - |
| K6148_RS28395 (101281) | 101281..101450 | - | 170 | Protein_124 | hypothetical protein | - |
| K6148_RS00625 (101646) | 101646..101876 | - | 231 | WP_001568040.1 | hypothetical protein | - |
| K6148_RS00630 (101939) | 101939..102610 | - | 672 | WP_013214012.1 | plasmid partitioning/stability family protein | - |
| K6148_RS00635 (102613) | 102613..103584 | - | 972 | WP_004152353.1 | plasmid segregation protein ParM | - |
| K6148_RS00640 (103818) | 103818..104249 | + | 432 | WP_001568036.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| K6148_RS00645 (104249) | 104249..105520 | + | 1272 | WP_004197646.1 | Y-family DNA polymerase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|