NZ_CP0820031..153399

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 153399 bp
Accession: NZ_CP082003        Location: 1..153399         Organism: Klebsiella pneumoniae strain KP18-1       Replicon: plasmid pKP18-1-KPC2


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6149_RS27905 (1) 1..720 + 720 WP_040120350.1 replication initiation protein -
K6149_RS27910 (2414) 2414..7273 + 4860 WP_040120352.1 DEAD/DEAH box helicase family protein -
K6149_RS27915 (8130) 8130..8456 - 327 WP_228301548.1 Tn3 family transposase TnBth3 Transposase
K6149_RS27920 (8447) 8447..9151 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6149_RS27925 (9203) 9203..9664 + 462 Protein_4 Tn3 family transposase TnpR_Tn3 Transposase
K6149_RS27930 (9787) 9787..10767 + 981 WP_013213985.1 IS481 family transposase ISKpn27 Transposase
K6149_RS27935 (11043) 11043..11924 + 882 WP_004199234.1 Carbapenem-hydrolyzing beta-lactamase KPC ARG
K6149_RS27940 (12174) 12174..13055 - 882 Protein_7 IS1182 family transposase ISKpn6 Transposase
K6149_RS27945 (13159) 13159..13455 - 297 WP_013213987.1 transcriptional regulator -
K6149_RS27950 (13501) 13501..13656 - 156 WP_013213988.1 hypothetical protein -
K6149_RS27955 (13784) 13784..14209 - 426 WP_013213989.1 antirestriction protein -
K6149_RS27960 (14320) 14320..14598 - 279 WP_013213990.1 hypothetical protein -
K6149_RS27965 (15132) 15132..15749 - 618 Protein_12 replication protein -
K6149_RS27970 (16141) 16141..16701 + 561 WP_001161490.1 Tn3 family transposase TnpR_TnAs1 Transposase
K6149_RS27975 (16705) 16705..17778 + 1074 Protein_14 Tn3 family transposase TnpA_TnAs1 Transposase
K6149_RS27980 (17831) 17831..18535 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6149_RS27985 (18759) 18759..18872 - 114 WP_014343462.1 hypothetical protein -
K6149_RS27990 (19408) 19408..20274 + 867 WP_004118283.1 replication initiation protein -
K6149_RS27995 (21384) 21384..22589 + 1206 WP_011977818.1 AAA family ATPase -
K6149_RS28000 (22589) 22589..23563 + 975 WP_011977819.1 ParB family protein -
K6149_RS28005 (23645) 23645..24916 - 1272 WP_013214011.1 Y-family DNA polymerase -
K6149_RS28010 (24916) 24916..25347 - 432 WP_001568036.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
K6149_RS28015 (25754) 25754..27241 + 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
K6149_RS28020 (27490) 27490..28461 + 972 WP_004152353.1 plasmid segregation protein ParM -
K6149_RS28025 (28464) 28464..29135 + 672 WP_013214012.1 plasmid partitioning/stability family protein -
K6149_RS28030 (29198) 29198..29428 + 231 WP_001568040.1 hypothetical protein -
K6149_RS29095 (29624) 29624..29793 + 170 Protein_26 hypothetical protein -
K6149_RS28035 (29865) 29865..30566 + 702 WP_001568041.1 DNA methylase -
K6149_RS28040 (30566) 30566..30787 + 222 WP_001568042.1 hypothetical protein -
K6149_RS28045 (30797) 30797..31216 + 420 WP_001568043.1 DUF1380 domain-containing protein -
K6149_RS28050 (31270) 31270..32037 + 768 WP_013214013.1 hypothetical protein -
K6149_RS28055 (32718) 32718..33146 + 429 WP_001568045.1 antirestriction protein -
K6149_RS28060 (33189) 33189..33695 + 507 WP_013214014.1 antirestriction protein ArdA -
K6149_RS28065 (33738) 33738..33929 + 192 WP_001568047.1 hypothetical protein -
K6149_RS28070 (34117) 34117..34371 + 255 WP_011977779.1 DNA polymerase III subunit theta -
K6149_RS28075 (34406) 34406..34726 + 321 WP_001568049.1 hypothetical protein -
K6149_RS28080 (35406) 35406..35633 + 228 WP_001568050.1 hypothetical protein -
K6149_RS28085 (35725) 35725..35955 + 231 WP_001568051.1 hypothetical protein -
K6149_RS28090 (36007) 36007..37362 + 1356 WP_014343515.1 DUF3560 domain-containing protein -
K6149_RS28095 (37410) 37410..37973 + 564 WP_014343514.1 methyltransferase -
K6149_RS28100 (38806) 38806..39348 + 543 WP_014343512.1 single-stranded DNA-binding protein -
K6149_RS28105 (39397) 39397..39645 + 249 WP_001568055.1 DUF905 domain-containing protein -
K6149_RS28110 (39715) 39715..41772 + 2058 WP_015493064.1 ParB/RepB/Spo0J family partition protein -
K6149_RS28115 (41817) 41817..42248 + 432 WP_001568057.1 conjugation system SOS inhibitor PsiB -
K6149_RS28120 (42245) 42245..42973 + 729 WP_001568058.1 plasmid SOS inhibition protein A -
K6149_RS28125 (42970) 42970..43296 + 327 WP_013023807.1 hypothetical protein -
K6149_RS28130 (43352) 43352..43726 + 375 WP_014343510.1 hypothetical protein -
K6149_RS29100 (43896) 43896..44045 + 150 Protein_47 DUF5431 family protein -
K6149_RS28135 (43996) 43996..44112 + 117 WP_055313929.1 type I toxin-antitoxin system Hok family toxin -
K6149_RS28140 (44805) 44805..45077 + 273 WP_040245921.1 hypothetical protein -
K6149_RS28145 (45074) 45074..45424 + 351 WP_040245917.1 hypothetical protein -
K6149_RS28150 (45439) 45439..45756 + 318 WP_014343505.1 hypothetical protein -
K6149_RS28155 (46597) 46597..46953 + 357 WP_014343501.1 hypothetical protein -
K6149_RS28160 (47014) 47014..47226 + 213 WP_014343500.1 hypothetical protein -
K6149_RS28165 (47237) 47237..47461 + 225 WP_014343499.1 hypothetical protein -
K6149_RS28170 (47542) 47542..47862 + 321 WP_014343498.1 type II toxin-antitoxin system RelE/ParE family toxin -
K6149_RS28175 (47852) 47852..48130 + 279 WP_004152721.1 helix-turn-helix transcriptional regulator -
K6149_RS29105 (48134) 48134..48238 + 105 Protein_57 transcriptional regulator -
K6149_RS28180 (48816) 48816..49520 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6149_RS28185 (49849) 49849..50799 + 951 WP_015493085.1 Recombination-promoting nuclease RpnA VF
K6149_RS28190 (50796) 50796..51407 - 612 WP_015493086.1 DUF2913 family protein -
K6149_RS28195 (51404) 51404..51799 - 396 WP_015493087.1 hypothetical protein -
K6149_RS28200 (51852) 51852..52244 - 393 Protein_62 3'-5' exonuclease -
K6149_RS28205 (52313) 52313..53293 + 981 WP_000019445.1 IS5 family transposase ISKpn26 Transposase
K6149_RS28210 (53275) 53275..53817 + 543 WP_077273850.1 restriction endonuclease -
K6149_RS28215 (53945) 53945..54502 + 558 WP_042934582.1 hypothetical protein -
K6149_RS28220 (54971) 54971..55675 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6149_RS28225 (55808) 55808..56449 - 642 WP_001011939.1 Chloramphenicol acetyltransferase 2 ARG
K6149_RS28230 (56599) 56599..57099 - 501 WP_001239317.1 hypothetical protein -
K6149_RS28235 (57179) 57179..57883 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6149_RS28240 (57889) 57889..58029 + 141 WP_001044210.1 hypothetical protein -
K6149_RS28245 (58515) 58515..59252 + 738 WP_001446887.1 Tn3 family transposase TnpR_TnEc1 Transposase
K6149_RS28250 (59249) 59249..59473 + 225 WP_000743213.1 hypothetical protein -
K6149_RS29110 (59595) 59595..59681 + 87 Protein_73 Arm DNA-binding domain-containing protein -
K6149_RS28260 (59953) 59953..60957 - 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
K6149_RS28265 (61036) 61036..64002 - 2967 WP_042863651.1 Tn3 family transposase TnpA_ISPa38 Transposase
K6149_RS28270 (64005) 64005..64070 - 66 Protein_76 helix-turn-helix domain-containing protein -
K6149_RS28275 (64123) 64123..64827 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6149_RS28280 (64852) 64852..65052 + 201 WP_072354025.1 hypothetical protein -
K6149_RS28285 (65072) 65072..65818 + 747 WP_000205770.1 conjugal transfer pilus acetylase TraX -
K6149_RS28290 (65873) 65873..66433 + 561 WP_000139328.1 fertility inhibition protein FinO -
K6149_RS28295 (66565) 66565..66765 + 201 WP_015059022.1 hypothetical protein -
K6149_RS28300 (67151) 67151..67750 + 600 WP_032083981.1 PIN domain-containing protein -
K6149_RS28305 (67812) 67812..68144 + 333 WP_152916585.1 hypothetical protein -
- (68345) 68345..68404 - 60 NuclAT_1 - Antitoxin Detail
- (68345) 68345..68404 - 60 NuclAT_1 - Antitoxin Detail
- (68345) 68345..68404 - 60 NuclAT_1 - Antitoxin Detail
- (68345) 68345..68404 - 60 NuclAT_1 - Antitoxin Detail
K6149_RS28310 (68449) 68449..68598 + 150 WP_001312851.1 Hok/Gef family protein Toxin Detail
K6149_RS28315 (68882) 68882..69130 + 249 WP_000083837.1 replication regulatory protein RepA -
K6149_RS29115 (69245) 69245..69423 + 179 Protein_86 protein CopA/IncA -
K6149_RS28325 (69442) 69442..70299 + 858 WP_142295464.1 incFII family plasmid replication initiator RepA -
K6149_RS28330 (71238) 71238..71891 + 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
K6149_RS28335 (71984) 71984..72241 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
K6149_RS28340 (72174) 72174..72575 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
K6149_RS28345 (72824) 72824..73239 + 416 Protein_91 IS1-like element IS1B family transposase -
K6149_RS28350 (73275) 73275..73820 - 546 Protein_92 Tn3 family transposase TnpA_Tn3 Transposase
K6149_RS28355 (73886) 73886..74590 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6149_RS28360 (74660) 74660..74851 + 192 Protein_94 IS1380 family transposase -
K6149_RS28365 (75101) 75101..75976 + 876 WP_013188475.1 Beta-lactamase Toho-1 ARG
K6149_RS28370 (76011) 76011..76979 + 969 WP_013362812.1 IS5 family transposase IS903B Transposase
K6149_RS28375 (77036) 77036..78133 + 1098 Protein_97 TonB-dependent receptor -
K6149_RS28380 (78201) 78201..78677 - 477 Protein_98 PAS domain-containing protein -
K6149_RS28385 (78730) 78730..79434 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6149_RS28390 (79820) 79820..80236 + 417 WP_014839980.1 Glutathione transferase FosA ARG
K6149_RS28395 (80241) 80241..80759 - 519 WP_014839979.1 FidL-like protein -
K6149_RS28400 (80825) 80825..81529 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6149_RS28405 (82002) 82002..82706 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6149_RS28410 (82772) 82772..82975 - 204 Protein_104 IS6 family transposase IS15 Transposase
K6149_RS28415 (82975) 82975..83703 - 729 WP_001230787.1 type-F conjugative transfer system secretin TraK -
K6149_RS28420 (83690) 83690..84256 - 567 WP_000399794.1 type IV conjugative transfer system protein TraE -
K6149_RS28425 (84278) 84278..84589 - 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
K6149_RS28430 (84604) 84604..84969 - 366 WP_021519752.1 type IV conjugative transfer system pilin TraA -
K6149_RS28435 (85003) 85003..85230 - 228 WP_001254386.1 conjugal transfer relaxosome protein TraY -
K6149_RS28440 (85324) 85324..86010 - 687 WP_015059009.1 PAS domain-containing protein -
K6149_RS28445 (86201) 86201..86584 - 384 WP_000124981.1 conjugal transfer relaxosome DNA-binding protein TraM -
K6149_RS28450 (86861) 86861..87508 + 648 WP_015059008.1 hypothetical protein VF
K6149_RS28455 (87805) 87805..88626 - 822 WP_001234445.1 DUF932 domain-containing protein -
K6149_RS28460 (88737) 88737..89033 - 297 WP_001272251.1 hypothetical protein -
K6149_RS28465 (89333) 89333..89629 + 297 Protein_115 hypothetical protein -
K6149_RS28470 (89948) 89948..90073 - 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
K6149_RS29125 (90015) 90015..90164 - 150 Protein_117 plasmid maintenance protein Mok -
- (90150) 90150..90374 - 225 NuclAT_0 - Antitoxin Detail
- (90150) 90150..90374 - 225 NuclAT_0 - Antitoxin Detail
- (90150) 90150..90374 - 225 NuclAT_0 - Antitoxin Detail
- (90150) 90150..90374 - 225 NuclAT_0 - Antitoxin Detail
K6149_RS28475 (90386) 90386..91105 - 720 WP_001276217.1 plasmid SOS inhibition protein A -
K6149_RS28480 (91102) 91102..91536 - 435 WP_000845953.1 conjugation system SOS inhibitor PsiB -
K6149_RS28485 (91605) 91605..93628 - 2024 Protein_120 ParB/RepB/Spo0J family partition protein -
K6149_RS28490 (93689) 93689..93922 - 234 WP_000006003.1 DUF905 family protein -
K6149_RS28495 (93980) 93980..94507 - 528 WP_000290834.1 single-stranded DNA-binding protein -
K6149_RS29130 (94809) 94809..95276 + 468 Protein_123 hypothetical protein -
K6149_RS28500 (95362) 95362..95925 - 564 WP_015059007.1 class I SAM-dependent methyltransferase -
K6149_RS28505 (95972) 95972..97333 - 1362 WP_000170695.1 DUF3560 domain-containing protein -
K6149_RS28510 (97385) 97385..97615 - 231 WP_000218642.1 hypothetical protein -
K6149_RS29135 (98132) 98132..98286 + 155 Protein_127 hypothetical protein -
K6149_RS28515 (99015) 99015..100682 + 1668 WP_012372796.1 group II intron reverse transcriptase/maturase -
K6149_RS28520 (100996) 100996..101187 - 192 WP_001027493.1 hypothetical protein -
K6149_RS28525 (101184) 101184..101606 - 423 WP_000271762.1 DUF1380 family protein -
K6149_RS28530 (101653) 101653..102078 - 426 WP_001198928.1 antirestriction protein -
K6149_RS28535 (102496) 102496..103272 - 777 WP_001383963.1 hypothetical protein -
K6149_RS28540 (103323) 103323..103757 - 435 WP_000274503.1 DUF1380 family protein -
K6149_RS28545 (103771) 103771..103992 - 222 WP_001104881.1 hypothetical protein -
K6149_RS28550 (103993) 103993..104676 - 684 WP_000085883.1 DNA methylase -
K6149_RS28555 (104753) 104753..105046 - 294 WP_032146011.1 hypothetical protein -
K6149_RS28560 (105193) 105193..106155 + 963 WP_000959884.1 plasmid segregation protein ParM -
K6149_RS28565 (106158) 106158..106508 + 351 WP_000361389.1 plasmid partitioning/stability family protein -
K6149_RS28570 (106631) 106631..106912 - 282 WP_001333089.1 hypothetical protein -
K6149_RS28575 (107040) 107040..107274 - 235 Protein_140 type II toxin-antitoxin system RelE/ParE family toxin -
K6149_RS28580 (108723) 108723..108788 - 66 Protein_141 IS1 family transposase -
K6149_RS28585 (108854) 108854..109558 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6149_RS28590 (109613) 109613..109927 + 315 Protein_143 hypothetical protein -
K6149_RS28595 (110008) 110008..110763 - 756 WP_012372818.1 16S rRNA (guanine(1405)-N(7))-methyltransferase ARG
K6149_RS28600 (110933) 110933..111793 - 861 WP_000027057.1 Beta-lactamase TEM ARG
K6149_RS28605 (111976) 111976..112512 - 537 WP_064441864.1 Tn3 family transposase TnpR_Tn3 Transposase
K6149_RS28610 (112604) 112604..112792 + 189 WP_000957857.1 hypothetical protein -
K6149_RS28615 (112802) 112802..113419 + 618 Protein_148 IS91 family transposase ISSbo1 Transposase
K6149_RS28620 (113470) 113470..114174 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6149_RS28625 (114239) 114239..114829 + 591 Protein_150 IS91 family transposase ISSbo1 Transposase
K6149_RS28630 (114936) 114936..115640 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6149_RS28635 (115531) 115531..116016 - 486 WP_228301550.1 Tn3 family transposase TnpR_ISPa38 Transposase
K6149_RS28640 (116256) 116256..117470 + 1215 WP_005012528.1 type II site-specific deoxyribonuclease -
K6149_RS28645 (117504) 117504..118937 - 1434 WP_001288432.1 DNA cytosine methyltransferase -
K6149_RS28650 (119036) 119036..119308 + 273 Protein_155 IS1 family transposase -
K6149_RS28655 (119319) 119319..119525 - 207 WP_001749967.1 hypothetical protein -
K6149_RS28660 (119530) 119530..120171 - 642 WP_012561158.1 restriction endonuclease -
K6149_RS28665 (120227) 120227..120538 - 312 WP_013279382.1 hypothetical protein -
K6149_RS28670 (120574) 120574..120888 - 315 WP_016338363.1 TrbM/KikA/MpfK family conjugal transfer protein -
K6149_RS28675 (120885) 120885..121229 - 345 WP_012561155.1 hypothetical protein -
K6149_RS28680 (121245) 121245..121550 - 306 WP_012561154.1 H-NS family nucleoid-associated regulatory protein -
K6149_RS28685 (121659) 121659..122396 + 738 WP_013279384.1 Type IV secretion system protein virB1 VF
K6149_RS28690 (122405) 122405..122686 + 282 WP_016338364.1 transcriptional repressor KorA -
K6149_RS28695 (122696) 122696..122989 + 294 WP_001749962.1 hypothetical protein -
K6149_RS28700 (123039) 123039..123356 + 318 WP_000496058.1 hypothetical protein VF
K6149_RS28705 (123356) 123356..125956 + 2601 WP_012561149.1 Type IV secretion system protein virB4 VF
K6149_RS28710 (125974) 125974..126687 + 714 WP_001749960.1 Type IV secretion system protein virB5 VF
K6149_RS28715 (126695) 126695..126922 + 228 WP_001749959.1 IncN-type entry exclusion lipoprotein EexN -
K6149_RS28720 (126938) 126938..127978 + 1041 WP_001749958.1 type IV secretion system protein -
K6149_RS28725 (128197) 128197..128895 + 699 WP_000646594.1 Type IV secretion system protein virB8 VF
K6149_RS28730 (128906) 128906..129790 + 885 WP_000735066.1 Type IV secretion system protein virB9 VF
K6149_RS28735 (129790) 129790..130950 + 1161 WP_012561145.1 Protein virB10 VF
K6149_RS28740 (130992) 130992..131987 + 996 WP_012561144.1 Type IV secretion system protein VirB11 VF
K6149_RS28745 (131987) 131987..132520 + 534 WP_000792636.1 Phospholipase D VF
K6149_RS28750 (132693) 132693..133007 - 315 WP_000091613.1 hypothetical protein -
K6149_RS28755 (133262) 133262..133618 - 357 WP_000215515.1 cupin domain-containing protein -
K6149_RS28760 (133608) 133608..134009 - 402 WP_001293886.1 DUF86 domain-containing protein -
K6149_RS28765 (134006) 134006..134296 - 291 WP_001247892.1 nucleotidyltransferase -
K6149_RS28770 (134360) 134360..134758 - 399 WP_012561143.1 hypothetical protein -
K6149_RS28775 (134758) 134758..137994 - 3237 WP_012561142.1 Multifunctional conjugation protein TraI Relaxase
K6149_RS28780 (137994) 137994..139523 - 1530 WP_000342688.1 type IV secretion system DNA-binding domain-containing protein -
K6149_RS28785 (139525) 139525..139941 - 417 WP_001749975.1 hypothetical protein -
K6149_RS28790 (140509) 140509..140895 + 387 WP_013279398.1 plasmid stabilization protein StbA -
K6149_RS28795 (140904) 140904..141620 + 717 WP_012561139.1 StbB family protein -
K6149_RS28800 (141622) 141622..141990 + 369 WP_012561138.1 plasmid stabilization protein StbC -
K6149_RS28805 (142191) 142191..142535 + 345 WP_012561137.1 hypothetical protein -
K6149_RS28810 (142997) 142997..143176 - 180 WP_012561134.1 protein CcgAI -
K6149_RS28815 (144007) 144007..144516 - 510 WP_012561131.1 antirestriction protein ArdA -
K6149_RS28820 (145867) 145867..146199 - 333 WP_040120360.1 hypothetical protein -
K6149_RS28825 (146408) 146408..146692 - 285 WP_013263793.1 protein CcgC -
K6149_RS29140 (146761) 146761..146961 - 201 WP_020319888.1 hypothetical protein -
K6149_RS28835 (147117) 147117..147413 - 297 WP_000545925.1 protein CcgD -
K6149_RS28840 (148297) 148297..148536 - 240 WP_032335150.1 hypothetical protein -
K6149_RS28845 (148546) 148546..148950 - 405 WP_000881513.1 antirestriction protein ArdAB regulator ArdR -
K6149_RS28850 (149008) 149008..149433 - 426 WP_000447669.1 antirestriction protein ArdB -
K6149_RS28855 (149849) 149849..150289 + 441 WP_000861760.1 translesion error-prone DNA polymerase V autoproteolytic subunit MucA -
K6149_RS28860 (150277) 150277..151542 + 1266 WP_012561122.1 translesion error-prone DNA polymerase V subunit MucB -
K6149_RS28865 (151693) 151693..152484 + 792 WP_012561121.1 SprT-like domain-containing protein -
K6149_RS28870 (152499) 152499..152840 - 342 WP_000057569.1 antirestriction protein ArdAB regulator ArdK -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance