MGE detailed information
MGE type: Conjugative plasmid MGE length: 125082 bp
Accession: NZ_CP080263 Location: 1..125082 Organism: Escherichia coli strain 135 Replicon: plasmid p135-3
Accession: NZ_CP080263 Location: 1..125082 Organism: Escherichia coli strain 135 Replicon: plasmid p135-3
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KZ312_RS27350 (1) | 1..435 | + | 435 | WP_029400524.1 | conjugation system SOS inhibitor PsiB | - |
| KZ312_RS27355 (432) | 432..1173 | + | 742 | Protein_1 | plasmid SOS inhibition protein A | - |
| - (1163) | 1163..1357 | + | 195 | NuclAT_0 | - | Antitoxin Detail |
| - (1163) | 1163..1357 | + | 195 | NuclAT_0 | - | Antitoxin Detail |
| - (1163) | 1163..1357 | + | 195 | NuclAT_0 | - | Antitoxin Detail |
| - (1163) | 1163..1357 | + | 195 | NuclAT_0 | - | Antitoxin Detail |
| KZ312_RS29220 (1364) | 1364..1513 | + | 150 | Protein_2 | DUF5431 family protein | - |
| KZ312_RS27360 (1455) | 1455..1580 | + | 126 | WP_096937776.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| KZ312_RS27365 (1673) | 1673..1837 | + | 165 | WP_001716565.1 | hypothetical protein | - |
| KZ312_RS27370 (2127) | 2127..2414 | + | 288 | WP_000107535.1 | hypothetical protein | - |
| KZ312_RS27375 (2533) | 2533..3354 | + | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| KZ312_RS27380 (3651) | 3651..4253 | - | 603 | WP_000243709.1 | hypothetical protein | VF |
| KZ312_RS27385 (4574) | 4574..4957 | + | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| KZ312_RS27390 (5144) | 5144..5833 | + | 690 | WP_029400181.1 | conjugal transfer transcriptional regulator TraJ | - |
| KZ312_RS27395 (5926) | 5926..6327 | + | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| KZ312_RS27400 (6360) | 6360..6719 | + | 360 | WP_000994781.1 | type IV conjugative transfer system pilin TraA | - |
| KZ312_RS27405 (6734) | 6734..7045 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| KZ312_RS27410 (7067) | 7067..7633 | + | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| KZ312_RS27415 (7620) | 7620..8348 | + | 729 | WP_029400178.1 | type-F conjugative transfer system secretin TraK | - |
| KZ312_RS27420 (8348) | 8348..9775 | + | 1428 | WP_023352033.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| KZ312_RS27425 (9765) | 9765..10355 | + | 591 | WP_023352032.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| KZ312_RS27430 (10342) | 10342..10662 | + | 321 | WP_001057305.1 | conjugal transfer protein TrbD | - |
| KZ312_RS27435 (10659) | 10659..11174 | + | 516 | WP_000809874.1 | type IV conjugative transfer system lipoprotein TraV | - |
| KZ312_RS27440 (11309) | 11309..11530 | + | 222 | WP_001278978.1 | conjugal transfer protein TraR | - |
| KZ312_RS27445 (11523) | 11523..11999 | + | 477 | WP_029400176.1 | hypothetical protein | - |
| KZ312_RS27450 (12079) | 12079..12297 | + | 219 | WP_000556751.1 | hypothetical protein | - |
| KZ312_RS27455 (12325) | 12325..12687 | + | 363 | WP_029400175.1 | hypothetical protein | - |
| KZ312_RS27460 (12813) | 12813..15443 | + | 2631 | WP_000069755.1 | type IV secretion system protein TraC | - |
| KZ312_RS27465 (15440) | 15440..15826 | + | 387 | WP_029400173.1 | type-F conjugative transfer system protein TrbI | - |
| KZ312_RS27470 (15823) | 15823..16455 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| KZ312_RS27475 (16452) | 16452..17444 | + | 993 | WP_000830839.1 | conjugal transfer pilus assembly protein TraU | - |
| KZ312_RS27480 (17453) | 17453..18091 | + | 639 | WP_029400171.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| KZ312_RS27485 (18088) | 18088..19896 | + | 1809 | WP_001567342.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| KZ312_RS27490 (19923) | 19923..20180 | + | 258 | WP_000864325.1 | conjugal transfer protein TrbE | - |
| KZ312_RS27495 (20173) | 20173..20916 | + | 744 | WP_001030376.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| KZ312_RS27500 (20932) | 20932..21279 | + | 348 | WP_001287893.1 | conjugal transfer protein TrbA | - |
| KZ312_RS27505 (21398) | 21398..21682 | + | 285 | WP_000624108.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| KZ312_RS27510 (21669) | 21669..22214 | + | 546 | WP_000060037.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| KZ312_RS27515 (22144) | 22144..22506 | + | 363 | WP_010379880.1 | P-type conjugative transfer protein TrbJ | - |
| KZ312_RS27520 (22506) | 22506..23879 | + | 1374 | WP_179193501.1 | conjugal transfer pilus assembly protein TraH | - |
| KZ312_RS27525 (23876) | 23876..26698 | + | 2823 | WP_001007026.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| KZ312_RS27530 (26713) | 26713..27216 | + | 504 | WP_000605510.1 | hypothetical protein | - |
| KZ312_RS27535 (27248) | 27248..27979 | + | 732 | WP_000850424.1 | conjugal transfer complement resistance protein TraT | - |
| KZ312_RS27540 (28232) | 28232..30430 | + | 2199 | WP_011402783.1 | type IV conjugative transfer system coupling protein TraD | - |
| KZ312_RS27545 (30430) | 30430..35700 | + | 5271 | WP_029400225.1 | Multifunctional conjugation protein TraI | Relaxase |
| KZ312_RS27550 (35720) | 35720..36466 | + | 747 | WP_000205764.1 | conjugal transfer pilus acetylase TraX | - |
| KZ312_RS27555 (36520) | 36520..37080 | + | 561 | WP_001567328.1 | fertility inhibition protein FinO | - |
| KZ312_RS27560 (37216) | 37216..37428 | + | 213 | WP_032303448.1 | hypothetical protein | - |
| KZ312_RS27565 (37674) | 37674..38135 | + | 462 | WP_059328048.1 | thermonuclease family protein | - |
| KZ312_RS27570 (38181) | 38181..38390 | + | 210 | WP_001299729.1 | hemolysin expression modulator Hha | - |
| KZ312_RS27575 (38429) | 38429..38931 | + | 503 | Protein_46 | DUF2726 domain-containing protein | - |
| - (39107) | 39107..39168 | - | 62 | NuclAT_1 | - | - |
| - (39107) | 39107..39168 | - | 62 | NuclAT_1 | - | - |
| - (39107) | 39107..39168 | - | 62 | NuclAT_1 | - | - |
| - (39107) | 39107..39168 | - | 62 | NuclAT_1 | - | - |
| KZ312_RS27580 (39212) | 39212..39361 | + | 150 | WP_001312851.1 | Hok/Gef family protein | - |
| KZ312_RS27585 (39645) | 39645..39893 | + | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
| KZ312_RS27590 (40139) | 40139..40213 | + | 75 | WP_032144212.1 | RepA leader peptide Tap | - |
| KZ312_RS27595 (40206) | 40206..41063 | + | 858 | WP_029400224.1 | incFII family plasmid replication initiator RepA | - |
| KZ312_RS27600 (42027) | 42027..42278 | + | 252 | WP_001132900.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| KZ312_RS27605 (42275) | 42275..42562 | + | 288 | WP_000222760.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| KZ312_RS29225 (42666) | 42666..42986 | + | 321 | Protein_53 | serine acetyltransferase | - |
| KZ312_RS27610 (43002) | 43002..43349 | - | 348 | Protein_54 | IS1-like element IS1A family transposase | - |
| KZ312_RS27615 (43438) | 43438..44459 | + | 1022 | Protein_55 | IS21 family transposase IS100kyp | Transposase |
| KZ312_RS27620 (44456) | 44456..45238 | + | 783 | WP_001442137.1 | IS21 family transposase IS100kyp | Transposase |
| KZ312_RS27625 (45293) | 45293..45657 | - | 365 | Protein_57 | IS1 family transposase | - |
| KZ312_RS27630 (45757) | 45757..46960 | + | 1204 | Protein_58 | ISL3 family transposase ISEc38 | Transposase |
| KZ312_RS27635 (47796) | 47796..48758 | - | 963 | WP_000661609.1 | carbamate kinase family protein | - |
| KZ312_RS27640 (48785) | 48785..50335 | - | 1551 | WP_001084509.1 | hypothetical protein | - |
| KZ312_RS27645 (50448) | 50448..51866 | - | 1419 | WP_000084168.1 | DUF1116 domain-containing protein | - |
| KZ312_RS27650 (51866) | 51866..53413 | - | 1548 | WP_000027750.1 | acyl-CoA synthetase FdrA | - |
| KZ312_RS27655 (53373) | 53373..54221 | - | 849 | WP_000531854.1 | DUF2877 domain-containing protein | - |
| KZ312_RS27660 (54307) | 54307..54912 | - | 606 | WP_000066154.1 | ankyrin repeat domain-containing protein | - |
| KZ312_RS27665 (55300) | 55300..56229 | + | 930 | WP_001084376.1 | putative HTH-type transcriptional regulator YahB | VF |
| KZ312_RS29230 (56704) | 56704..57545 | - | 842 | Protein_66 | hypothetical protein | - |
| KZ312_RS27675 (57888) | 57888..58585 | + | 698 | WP_094096600.1 | IS1 family transposase IS1S | Transposase |
| KZ312_RS27680 (58601) | 58601..58879 | + | 279 | Protein_68 | serine acetyltransferase | - |
| KZ312_RS27685 (58982) | 58982..59647 | + | 666 | WP_000536047.1 | ProQ/FINO family protein | - |
| KZ312_RS27690 (59705) | 59705..59995 | + | 291 | WP_000633743.1 | hypothetical protein | - |
| KZ312_RS27695 (60673) | 60673..61170 | - | 498 | WP_032297276.1 | Multidrug resistance ABC transporter ATP-binding/permease protein BmrA | VF |
| KZ312_RS27700 (61144) | 61144..62132 | - | 989 | Protein_72 | Multidrug resistance ABC transporter ATP-binding/permease protein BmrA | VF |
| KZ312_RS27705 (62384) | 62384..62773 | - | 390 | WP_000595317.1 | cytochrome b562 | - |
| KZ312_RS27710 (63207) | 63207..64097 | - | 891 | WP_000470711.1 | putative HTH-type transcriptional regulator YahB | VF |
| KZ312_RS27715 (64175) | 64175..65398 | - | 1224 | WP_024188138.1 | cytosine permease | - |
| KZ312_RS27720 (65421) | 65421..65810 | - | 390 | WP_001696803.1 | hypothetical protein | - |
| KZ312_RS27725 (65827) | 65827..66783 | - | 957 | WP_001696801.1 | carbamate kinase | - |
| KZ312_RS27730 (66776) | 66776..68197 | - | 1422 | WP_219790179.1 | DUF1116 domain-containing protein | - |
| KZ312_RS27735 (68194) | 68194..69753 | - | 1560 | WP_000865634.1 | acyl-CoA synthetase FdrA | - |
| KZ312_RS27740 (69848) | 69848..70708 | - | 861 | WP_001442105.1 | DUF2877 domain-containing protein | - |
| KZ312_RS27745 (70714) | 70714..71382 | - | 669 | WP_000155780.1 | cysteine hydrolase | - |
| KZ312_RS29235 (71652) | 71652..71736 | - | 85 | Protein_82 | hypothetical protein | - |
| KZ312_RS27750 (71841) | 71841..72272 | - | 432 | Protein_83 | relaxase NikB | - |
| KZ312_RS27755 (72326) | 72326..73539 | + | 1214 | WP_162829202.1 | IS3 family transposase IS1203 | Transposase |
| KZ312_RS27760 (73554) | 73554..73747 | + | 194 | Protein_85 | transposase zinc-binding domain-containing protein | - |
| KZ312_RS27765 (73952) | 73952..74962 | + | 1011 | WP_000487120.1 | IS110 family transposase IS1663 | Transposase |
| KZ312_RS27770 (75540) | 75540..76130 | + | 591 | WP_000086538.1 | Tn3 family transposase TnpR_ISSba14 | Transposase |
| KZ312_RS27775 (76222) | 76222..77226 | + | 1005 | WP_000427623.1 | IS110 family transposase IS4321R | Transposase |
| KZ312_RS27780 (77504) | 77504..77662 | + | 159 | Protein_89 | integrase core domain-containing protein | - |
| KZ312_RS27785 (77812) | 77812..78810 | + | 999 | WP_000756335.1 | ABC transporter substrate-binding protein | - |
| KZ312_RS27790 (78810) | 78810..79850 | + | 1041 | WP_219790180.1 | Hemin transport system permease protein HmuU | VF |
| KZ312_RS27795 (79850) | 79850..80611 | + | 762 | WP_000020503.1 | Fe(3+) dicitrate transport ATP-binding protein FecE | VF |
| KZ312_RS27800 (80668) | 80668..81855 | + | 1188 | WP_025999368.1 | MFS transporter | - |
| KZ312_RS27805 (81933) | 81933..82190 | - | 258 | WP_000412701.1 | bacteriocin immunity protein | - |
| KZ312_RS27810 (82191) | 82191..82424 | - | 234 | WP_000451769.1 | HNH endonuclease signature motif containing protein | - |
| KZ312_RS27815 (82520) | 82520..82791 | + | 272 | Protein_96 | hypothetical protein | - |
| KZ312_RS27820 (82952) | 82952..83131 | - | 180 | Protein_97 | 3'-5' exonuclease | - |
| KZ312_RS27825 (83177) | 83177..83344 | - | 168 | Protein_98 | type II toxin-antitoxin system toxin YacB | - |
| KZ312_RS27830 (83341) | 83341..84171 | + | 831 | Protein_99 | IS66 family transposase ISEc43 | Transposase |
| KZ312_RS27835 (84215) | 84215..84863 | - | 649 | Protein_100 | IS3 family transposase IS1203 | Transposase |
| KZ312_RS27840 (85159) | 85159..85512 | - | 354 | WP_000990989.1 | hypothetical protein | - |
| KZ312_RS27845 (85584) | 85584..85832 | - | 249 | WP_000467268.1 | DUF883 family protein | - |
| KZ312_RS27850 (86417) | 86417..86734 | - | 318 | WP_000845366.1 | Major pilu subunit operon regulatory protein PapB | VF |
| KZ312_RS27855 (87401) | 87401..88393 | - | 993 | WP_219790181.1 | nuclease PIN | - |
| KZ312_RS27860 (88422) | 88422..88931 | - | 510 | WP_157916444.1 | Minor fimbrial protein PrsF | VF |
| KZ312_RS27865 (88963) | 88963..89424 | - | 462 | WP_242791976.1 | hypothetical protein | VF |
| KZ312_RS27870 (89515) | 89515..90246 | - | 732 | WP_001171047.1 | Chaperone protein PapD | VF |
| KZ312_RS27875 (90315) | 90315..92825 | - | 2511 | WP_029400265.1 | Outer membrane usher protein PapC | VF |
| KZ312_RS27880 (92946) | 92946..93521 | - | 576 | WP_223942798.1 | PAP fimbrial minor pilin protein | VF |
| KZ312_RS27885 (93620) | 93620..94147 | - | 528 | WP_001045099.1 | Pap fimbrial major pilin protein | VF |
| KZ312_RS27890 (95237) | 95237..96214 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| KZ312_RS27895 (96499) | 96499..97239 | - | 741 | WP_001066953.1 | tyrosine-type recombinase/integrase | - |
| KZ312_RS27900 (97360) | 97360..97548 | - | 189 | WP_059328029.1 | hypothetical protein | - |
| KZ312_RS27905 (97923) | 97923..98825 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| KZ312_RS27910 (98894) | 98894..100003 | - | 1110 | WP_059328030.1 | SDR family oxidoreductase | - |
| KZ312_RS27915 (100436) | 100436..101389 | - | 954 | WP_000280979.1 | Protease 7 | VF |
| KZ312_RS29240 (102642) | 102642..103042 | - | 401 | Protein_117 | integrase core domain-containing protein | - |
| KZ312_RS27925 (103052) | 103052..103377 | - | 326 | Protein_118 | IS3 family transposase ISLad1 | Transposase |
| KZ312_RS29245 (103423) | 103423..103763 | + | 341 | Protein_119 | IS3 family transposase | - |
| KZ312_RS27930 (104358) | 104358..105545 | + | 1188 | WP_000928805.1 | efflux RND transporter periplasmic adaptor subunit | - |
| KZ312_RS27935 (105542) | 105542..107482 | + | 1941 | WP_000733250.1 | Macrolide export ATP-binding/permease protein MacB | VF |
| KZ312_RS27940 (107486) | 107486..108856 | + | 1371 | WP_001318212.1 | efflux transporter outer membrane subunit | - |
| KZ312_RS27950 (110075) | 110075..111286 | + | 1212 | Protein_124 | IS3 family transposase | - |
| KZ312_RS27955 (111654) | 111654..113534 | + | 1881 | WP_059328027.1 | colicin Ia central receptor-binding domain-containing protein | - |
| KZ312_RS27960 (113556) | 113556..113891 | - | 336 | WP_029400677.1 | colicin 1A immunity protein | - |
| KZ312_RS27965 (114020) | 114020..114367 | + | 348 | WP_000142451.1 | DUF6404 family protein | - |
| KZ312_RS27970 (114387) | 114387..114776 | - | 390 | Protein_128 | hypothetical protein | - |
| KZ312_RS27975 (114929) | 114929..115381 | + | 453 | WP_001519992.1 | acyltransferase | - |
| KZ312_RS27980 (115770) | 115770..116528 | - | 759 | Protein_130 | IS21 family transposase | - |
| KZ312_RS27985 (116650) | 116650..116847 | + | 198 | Protein_131 | CcdB family protein | - |
| KZ312_RS27990 (117310) | 117310..118476 | + | 1167 | WP_001519994.1 | Sporulation initiation inhibitor protein Soj | VF |
| KZ312_RS27995 (118476) | 118476..119447 | + | 972 | WP_001519995.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| KZ312_RS29250 (119737) | 119737..119908 | + | 172 | Protein_134 | hypothetical protein | - |
| KZ312_RS28000 (120298) | 120298..120723 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| KZ312_RS28005 (120770) | 120770..121192 | + | 423 | WP_001587500.1 | DUF1380 family protein | - |
| KZ312_RS28010 (121189) | 121189..121380 | + | 192 | WP_001027500.1 | hypothetical protein | - |
| KZ312_RS29255 (121359) | 121359..121878 | - | 520 | Protein_138 | hypothetical protein | - |
| KZ312_RS28015 (121948) | 121948..122154 | + | 207 | WP_029400906.1 | hypothetical protein | - |
| KZ312_RS28020 (122180) | 122180..122707 | + | 528 | WP_000290825.1 | single-stranded DNA-binding protein | - |
| KZ312_RS28025 (122765) | 122765..122998 | + | 234 | WP_000005990.1 | DUF905 family protein | - |
| KZ312_RS28030 (123064) | 123064..125028 | + | 1965 | WP_001587501.1 | ParB/RepB/Spo0J family partition protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|