MGE detailed information
MGE type: Conjugative plasmid MGE length: 135777 bp
Accession: NZ_CP080261 Location: 1..135777 Organism: Escherichia coli strain 135 Replicon: plasmid p135-1
Accession: NZ_CP080261 Location: 1..135777 Organism: Escherichia coli strain 135 Replicon: plasmid p135-1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KZ312_RS25800 (KZ312_25800) | 1..987 | + | 987 | WP_113404234.1 | Recombination-promoting nuclease RpnD | VF |
| KZ312_RS25805 (KZ312_25805) | 1050..1211 | + | 162 | WP_000150306.1 | hypothetical protein | - |
| KZ312_RS25810 (KZ312_25810) | 1270..1464 | + | 195 | WP_032266355.1 | hypothetical protein | - |
| KZ312_RS25815 (KZ312_25815) | 1495..1746 | - | 252 | WP_000148285.1 | helix-turn-helix transcriptional regulator | - |
| KZ312_RS25820 (KZ312_25820) | 1907..2083 | - | 177 | WP_174243710.1 | hypothetical protein | - |
| KZ312_RS25825 (KZ312_25825) | 2327..3175 | + | 849 | WP_219790169.1 | DUF4942 domain-containing protein | - |
| KZ312_RS25830 (KZ312_25830) | 3261..3596 | - | 336 | WP_000157103.1 | hypothetical protein | - |
| KZ312_RS25835 (KZ312_25835) | 3829..4161 | + | 333 | WP_001291056.1 | plasmid mobilization protein MobA | - |
| KZ312_RS25840 (KZ312_25840) | 4173..6884 | + | 2712 | WP_072770402.1 | Protein TraI | Relaxase |
| KZ312_RS25845 (KZ312_25845) | 6952..7083 | + | 132 | Protein_9 | tolA family protein | - |
| KZ312_RS25850 (KZ312_25850) | 7067..7858 | + | 792 | Protein_10 | IS3 family transposase IS629 | Transposase |
| KZ312_RS25855 (KZ312_25855) | 9128..9825 | + | 698 | WP_249940384.1 | IS1-like element IS1A family transposase | - |
| KZ312_RS25860 (KZ312_25860) | 10824..12017 | - | 1194 | Protein_12 | IS3 family transposase IS629 | Transposase |
| KZ312_RS25865 (KZ312_25865) | 12607..14910 | - | 2304 | WP_072770368.1 | F-type conjugative transfer protein TrbC | - |
| KZ312_RS25870 (KZ312_25870) | 14891..16009 | - | 1119 | WP_106108236.1 | DsbC family protein | - |
| KZ312_RS25875 (KZ312_25875) | 16006..17241 | - | 1236 | WP_244611469.1 | IncI1-type conjugal transfer protein TrbA | - |
| KZ312_RS25880 (KZ312_25880) | 17941..18408 | - | 468 | WP_045145415.1 | thermonuclease family protein | - |
| KZ312_RS25885 (KZ312_25885) | 18573..19196 | + | 624 | WP_045145414.1 | helix-turn-helix domain-containing protein | - |
| KZ312_RS25890 (KZ312_25890) | 19394..19609 | - | 216 | WP_000266543.1 | hypothetical protein | - |
| KZ312_RS25895 (KZ312_25895) | 19613..19981 | - | 369 | WP_001302696.1 | hypothetical protein | - |
| KZ312_RS25900 (KZ312_25900) | 19993..20184 | - | 192 | WP_000751583.1 | hypothetical protein | - |
| KZ312_RS25905 (KZ312_25905) | 20281..20523 | - | 243 | WP_000650933.1 | hypothetical protein | - |
| KZ312_RS25910 (KZ312_25910) | 20852..21004 | + | 153 | WP_021532728.1 | Hok/Gef family protein | - |
| KZ312_RS25915 (KZ312_25915) | 21573..21725 | + | 153 | WP_001367784.1 | Hok/Gef family protein | - |
| KZ312_RS25920 (KZ312_25920) | 21722..21883 | - | 162 | WP_021580032.1 | hypothetical protein | - |
| KZ312_RS29170 | 22039..22170 | - | 132 | Protein_25 | ethanolamine utilization protein EutE | - |
| KZ312_RS25925 (KZ312_25925) | 22265..22474 | + | 210 | WP_000062946.1 | HEAT repeat domain-containing protein | - |
| KZ312_RS25930 (KZ312_25930) | 22539..23186 | - | 648 | WP_072643575.1 | plasmid IncI1-type surface exclusion protein ExcA | - |
| KZ312_RS25935 (KZ312_25935) | 23274..25433 | - | 2160 | WP_058100846.1 | DotA/TraY family protein | - |
| KZ312_RS25940 (KZ312_25940) | 25506..26075 | - | 570 | WP_058100845.1 | conjugal transfer protein TraX | - |
| KZ312_RS25945 (KZ312_25945) | 26072..27277 | - | 1206 | WP_052908626.1 | conjugal transfer protein TraW | - |
| KZ312_RS25950 (KZ312_25950) | 27238..27855 | - | 618 | WP_052908627.1 | hypothetical protein | - |
| KZ312_RS25955 (KZ312_25955) | 27855..30899 | - | 3045 | WP_058100844.1 | conjugal transfer protein | - |
| KZ312_RS25960 (KZ312_25960) | 31075..31458 | - | 384 | WP_227316922.1 | hypothetical protein | - |
| KZ312_RS25965 (KZ312_25965) | 31455..31814 | - | 360 | WP_058100842.1 | hypothetical protein | - |
| KZ312_RS25970 (KZ312_25970) | 31871..32689 | - | 819 | WP_072195912.1 | conjugal transfer protein TraT | - |
| KZ312_RS29175 | 32703..32855 | - | 153 | Protein_36 | TraS | - |
| KZ312_RS25980 (KZ312_25980) | 32912..33310 | - | 399 | WP_021532718.1 | hypothetical protein | - |
| KZ312_RS25985 (KZ312_25985) | 33357..33887 | - | 531 | WP_227316726.1 | conjugal transfer protein TraQ | - |
| KZ312_RS25990 (KZ312_25990) | 33884..34597 | - | 714 | WP_072657236.1 | conjugal transfer protein TraP | - |
| KZ312_RS25995 (KZ312_25995) | 34594..35925 | - | 1332 | WP_058100840.1 | conjugal transfer protein TraO | - |
| KZ312_RS26000 (KZ312_26000) | 35929..36903 | - | 975 | WP_021532715.1 | hypothetical protein | VF |
| KZ312_RS26005 (KZ312_26005) | 36914..37609 | - | 696 | WP_029391932.1 | DotI/IcmL family type IV secretion protein | - |
| KZ312_RS26010 (KZ312_26010) | 37621..37971 | - | 351 | WP_021532713.1 | hypothetical protein | - |
| KZ312_RS26015 (KZ312_26015) | 37988..42049 | - | 4062 | WP_072749266.1 | DUF5710 domain-containing protein | - |
| KZ312_RS26020 (KZ312_26020) | 42113..42403 | - | 291 | WP_000817799.1 | hypothetical protein | - |
| KZ312_RS26025 (KZ312_26025) | 42400..43548 | - | 1149 | WP_058100838.1 | putative protein YggR | VF |
| KZ312_RS26030 (KZ312_26030) | 43532..44367 | - | 836 | Protein_47 | type IV secretion system DotC family protein | - |
| KZ312_RS26035 (KZ312_26035) | 44364..44822 | - | 459 | WP_001170111.1 | DotD/TraH family lipoprotein | - |
| KZ312_RS26040 (KZ312_26040) | 44926..46128 | - | 1203 | WP_053287757.1 | conjugal transfer protein TraF | - |
| KZ312_RS26045 (KZ312_26045) | 46230..47051 | - | 822 | WP_001681675.1 | hypothetical protein | - |
| KZ312_RS26050 (KZ312_26050) | 47325..47645 | + | 321 | WP_000695052.1 | hypothetical protein | - |
| KZ312_RS26055 (KZ312_26055) | 47737..48027 | - | 291 | WP_021532709.1 | hypothetical protein | - |
| KZ312_RS26060 (KZ312_26060) | 48069..49238 | - | 1170 | WP_021532708.1 | site-specific integrase | - |
| KZ312_RS29180 | 49744..50229 | + | 486 | WP_250193838.1 | prepilin, shufflon protein A | - |
| KZ312_RS26070 (KZ312_26070) | 50234..50584 | - | 351 | WP_096996321.1 | phage tail protein | - |
| KZ312_RS26075 (KZ312_26075) | 50855..52102 | - | 1248 | WP_072692284.1 | hypothetical protein | VF |
| KZ312_RS26080 (KZ312_26080) | 52099..52731 | - | 633 | WP_244611477.1 | A24 family peptidase | - |
| KZ312_RS26085 (KZ312_26085) | 52766..53242 | - | 477 | WP_029391914.1 | hypothetical protein | VF |
| KZ312_RS26090 (KZ312_26090) | 53301..53837 | - | 537 | WP_058100836.1 | type 4 pilus major pilin | - |
| KZ312_RS26095 (KZ312_26095) | 53887..54987 | - | 1101 | WP_001696153.1 | Toxin coregulated pilus biosynthesis protein E | VF |
| KZ312_RS26100 (KZ312_26100) | 54989..56497 | - | 1509 | WP_058100835.1 | Type II secretion system protein E | VF |
| KZ312_RS26105 (KZ312_26105) | 56594..57190 | - | 597 | WP_029391917.1 | hypothetical protein | - |
| KZ312_RS26110 (KZ312_26110) | 57286..57840 | - | 555 | WP_021532699.1 | hypothetical protein | - |
| KZ312_RS29185 | 57889..58161 | - | 273 | WP_258056661.1 | hypothetical protein | VF |
| KZ312_RS26120 (KZ312_26120) | 58333..59628 | - | 1296 | WP_077250483.1 | type 4b pilus protein PilO2 | - |
| KZ312_RS26125 (KZ312_26125) | 59649..61268 | - | 1620 | WP_021532696.1 | Outer membrane lipoprotein BfpB | VF |
| KZ312_RS26130 (KZ312_26130) | 61299..61736 | - | 438 | WP_021532695.1 | type IV pilus biogenesis protein PilM | - |
| KZ312_RS26135 (KZ312_26135) | 61741..62811 | - | 1071 | WP_072643480.1 | hypothetical protein | VF |
| KZ312_RS26140 (KZ312_26140) | 62933..63328 | + | 396 | WP_058100832.1 | hypothetical protein | - |
| KZ312_RS29190 | 63833..64075 | - | 243 | WP_021532691.1 | PilI type IV pilus biogenesis protein | - |
| KZ312_RS29195 | 64136..64309 | - | 174 | Protein_71 | hypothetical protein | - |
| KZ312_RS26150 (KZ312_26150) | 64352..65017 | - | 666 | WP_058100831.1 | traC | - |
| KZ312_RS26155 (KZ312_26155) | 65158..65666 | - | 509 | Protein_73 | transcription termination factor NusG | - |
| KZ312_RS26160 (KZ312_26160) | 66504..67376 | + | 873 | WP_000729438.1 | incFII family plasmid replication initiator RepA | - |
| KZ312_RS26165 (KZ312_26165) | 68323..68574 | + | 252 | WP_045145550.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| KZ312_RS26170 (KZ312_26170) | 68571..68858 | + | 288 | WP_032353555.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| KZ312_RS26175 (KZ312_26175) | 69138..69815 | + | 678 | WP_072740705.1 | IS66 family transposase ISCro1 | Transposase |
| KZ312_RS26180 (KZ312_26180) | 69815..70162 | + | 348 | WP_000624618.1 | IS66 family transposase ISCro1 | Transposase |
| KZ312_RS26185 (KZ312_26185) | 70182..71753 | + | 1572 | WP_106487386.1 | IS66 family transposase ISCro1 | Transposase |
| KZ312_RS26190 (KZ312_26190) | 72364..72852 | + | 489 | WP_072157196.1 | Serine acetyltransferase | VF |
| KZ312_RS26195 (KZ312_26195) | 73132..73725 | - | 594 | WP_032353553.1 | ProQ/FINO family protein | - |
| KZ312_RS26200 (KZ312_26200) | 74579..75766 | - | 1188 | WP_045145541.1 | IS91 family transposase ISEc37 | Transposase |
| KZ312_RS26205 (KZ312_26205) | 75766..76131 | - | 366 | WP_032353961.1 | hypothetical protein | - |
| KZ312_RS26210 (KZ312_26210) | 76150..76512 | + | 363 | WP_225556432.1 | hypothetical protein | - |
| KZ312_RS26215 (KZ312_26215) | 76541..77104 | + | 564 | WP_032353959.1 | pentapeptide repeat-containing protein | - |
| KZ312_RS26220 (KZ312_26220) | 77305..77505 | - | 201 | Protein_86 | IS256 family transposase | - |
| KZ312_RS26230 (KZ312_26230) | 78840..79115 | - | 276 | WP_032354012.1 | PerC family transcriptional regulator | - |
| KZ312_RS26235 (KZ312_26235) | 79205..79939 | + | 735 | WP_032354011.1 | helix-turn-helix domain-containing protein | - |
| KZ312_RS26240 (KZ312_26240) | 80094..80276 | - | 183 | Protein_90 | iron-containing alcohol dehydrogenase | - |
| KZ312_RS26245 (KZ312_26245) | 80349..81092 | + | 744 | Protein_91 | IS3 family transposase ISKpn38 | Transposase |
| KZ312_RS26250 (KZ312_26250) | 81265..82464 | - | 1200 | WP_000948429.1 | IS91 family transposase ISSbo1 | Transposase |
| KZ312_RS26255 (KZ312_26255) | 82474..82662 | - | 189 | WP_000957857.1 | hypothetical protein | - |
| KZ312_RS26260 (KZ312_26260) | 82795..83385 | + | 591 | WP_000086536.1 | Tn3 family transposase TnpR_ISSba14 | Transposase |
| KZ312_RS26265 (KZ312_26265) | 83477..84481 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| KZ312_RS26270 (KZ312_26270) | 84759..84917 | + | 159 | Protein_96 | integrase core domain-containing protein | - |
| KZ312_RS26275 (KZ312_26275) | 85067..86065 | + | 999 | WP_032353474.1 | ABC transporter substrate-binding protein | - |
| KZ312_RS26280 (KZ312_26280) | 86065..87102 | + | 1038 | WP_032353476.1 | Fe(3+) dicitrate transport system permease protein FecD | VF |
| KZ312_RS26285 (KZ312_26285) | 87102..87861 | + | 760 | Protein_99 | Fe(3+) dicitrate transport ATP-binding protein FecE | VF |
| KZ312_RS26290 (KZ312_26290) | 87918..89105 | + | 1188 | WP_160377741.1 | Fe(3+) dicitrate transport ATP-binding protein FecE | VF |
| KZ312_RS26295 (KZ312_26295) | 89183..89350 | - | 168 | Protein_101 | bacteriocin immunity protein | - |
| KZ312_RS26300 (KZ312_26300) | 89414..90111 | + | 698 | WP_103215986.1 | IS1-like element IS1A family transposase | - |
| KZ312_RS26305 (KZ312_26305) | 90105..90389 | - | 285 | WP_258056635.1 | hypothetical protein | - |
| KZ312_RS26310 (KZ312_26310) | 90823..91713 | - | 891 | WP_000470711.1 | putative HTH-type transcriptional regulator YahB | VF |
| KZ312_RS26315 (KZ312_26315) | 91791..93014 | - | 1224 | WP_024188138.1 | cytosine permease | - |
| KZ312_RS26320 (KZ312_26320) | 93037..93426 | - | 390 | WP_001696803.1 | hypothetical protein | - |
| KZ312_RS26325 (KZ312_26325) | 93443..94399 | - | 957 | WP_032353537.1 | carbamate kinase | - |
| KZ312_RS26330 (KZ312_26330) | 94392..95816 | - | 1425 | WP_053287902.1 | DUF1116 domain-containing protein | - |
| KZ312_RS26335 (KZ312_26335) | 95813..97376 | - | 1564 | Protein_109 | acyl-CoA synthetase FdrA | - |
| KZ312_RS26340 (KZ312_26340) | 97471..98331 | - | 861 | WP_001442105.1 | DUF2877 domain-containing protein | - |
| KZ312_RS26345 (KZ312_26345) | 98337..99005 | - | 669 | WP_000155780.1 | cysteine hydrolase | - |
| KZ312_RS26350 (KZ312_26350) | 99490..100986 | - | 1497 | WP_000716410.1 | carbohydrate porin | - |
| KZ312_RS26355 (KZ312_26355) | 101086..102012 | - | 927 | WP_000108760.1 | aminoimidazole riboside kinase | - |
| KZ312_RS26360 (KZ312_26360) | 102042..102353 | - | 312 | WP_001313183.1 | DUF2913 family protein | - |
| KZ312_RS26365 (KZ312_26365) | 102415..102618 | - | 204 | WP_001313182.1 | DUF2913 family protein | - |
| KZ312_RS26370 (KZ312_26370) | 102624..103139 | - | 516 | WP_072740749.1 | PTS glucose transporter subunit IIA | - |
| KZ312_RS26375 (KZ312_26375) | 103203..104633 | - | 1431 | WP_000813683.1 | glycoside hydrolase family 32 protein | - |
| KZ312_RS26380 (KZ312_26380) | 104630..105907 | - | 1278 | WP_001099190.1 | MFS transporter | - |
| KZ312_RS26385 (KZ312_26385) | 105962..108088 | - | 2127 | WP_000433621.1 | alpha-galactosidase | - |
| KZ312_RS26390 (KZ312_26390) | 108182..108883 | - | 702 | Protein_120 | substrate-binding domain-containing protein | - |
| KZ312_RS26395 (KZ312_26395) | 108980..110208 | + | 1229 | WP_088895425.1 | IS3 family transposase IS2 | Transposase |
| KZ312_RS26400 (KZ312_26400) | 110401..111608 | + | 1208 | WP_096990783.1 | IS3 family transposase ISEc48 | Transposase |
| KZ312_RS26405 (KZ312_26405) | 112074..112526 | + | 453 | WP_000670963.1 | acyltransferase | - |
| KZ312_RS26410 (KZ312_26410) | 112558..112743 | - | 186 | WP_032353630.1 | hypothetical protein | - |
| KZ312_RS26415 (KZ312_26415) | 112791..112922 | - | 132 | Protein_125 | IS3 family transposase ISSfl10 | Transposase |
| KZ312_RS26420 (KZ312_26420) | 113904..114122 | + | 219 | WP_000813630.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| KZ312_RS26425 (KZ312_26425) | 114124..114429 | + | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| KZ312_RS26430 (KZ312_26430) | 114430..115239 | + | 810 | WP_045145707.1 | site-specific integrase | - |
| KZ312_RS26435 (KZ312_26435) | 115412..115765 | + | 354 | WP_000864812.1 | colicin M immunity protein | - |
| KZ312_RS26440 (KZ312_26440) | 115815..116630 | - | 816 | WP_000449473.1 | lipid II-degrading bacteriocin colicin M | - |
| KZ312_RS26445 (KZ312_26445) | 116872..117399 | + | 528 | WP_032353548.1 | colicin B immunity protein | - |
| KZ312_RS26450 (KZ312_26450) | 117417..118076 | - | 660 | Protein_132 | colicin-like pore-forming protein | - |
| KZ312_RS26455 (KZ312_26455) | 118137..118834 | + | 698 | WP_249940384.1 | IS1-like element IS1A family transposase | - |
| KZ312_RS26460 (KZ312_26460) | 118851..119729 | - | 879 | Protein_134 | colicin-B | - |
| KZ312_RS26465 (KZ312_26465) | 119915..120403 | + | 489 | Protein_135 | IS91 family transposase ISSod25 | Transposase |
| KZ312_RS26470 (KZ312_26470) | 120540..120815 | - | 276 | WP_001536593.1 | hypothetical protein | - |
| KZ312_RS26475 (KZ312_26475) | 120809..121453 | - | 645 | WP_000633911.1 | AAA family ATPase | - |
| KZ312_RS26480 (KZ312_26480) | 121682..122653 | + | 972 | WP_021580010.1 | plasmid segregation protein ParM | - |
| KZ312_RS26485 (KZ312_26485) | 122658..123050 | + | 393 | WP_000340830.1 | plasmid partitioning/stability family protein | - |
| KZ312_RS26490 (KZ312_26490) | 123055..124326 | - | 1272 | WP_000457496.1 | Y-family DNA polymerase | - |
| KZ312_RS26495 (KZ312_26495) | 124326..124763 | - | 438 | WP_000109071.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| KZ312_RS26500 (KZ312_26500) | 124760..125008 | - | 249 | WP_000618110.1 | DinI-like family protein | - |
| KZ312_RS26505 (KZ312_26505) | 125426..126328 | + | 903 | WP_139244410.1 | DUF1281 domain-containing protein | - |
| KZ312_RS29200 | 126292..126387 | + | 96 | Protein_144 | hypothetical protein | - |
| KZ312_RS26510 (KZ312_26510) | 126734..127159 | + | 426 | WP_072740720.1 | antirestriction protein | - |
| KZ312_RS26515 (KZ312_26515) | 127206..127625 | + | 420 | WP_000271736.1 | DUF1380 family protein | - |
| KZ312_RS26520 (KZ312_26520) | 127625..127816 | + | 192 | WP_001027495.1 | hypothetical protein | - |
| KZ312_RS26525 (KZ312_26525) | 128149..128217 | - | 69 | Protein_148 | pilus protein | - |
| KZ312_RS26530 (KZ312_26530) | 128586..129113 | + | 528 | WP_029391983.1 | single-stranded DNA-binding protein | - |
| KZ312_RS26535 (KZ312_26535) | 129171..129404 | + | 234 | WP_021534894.1 | DUF905 domain-containing protein | - |
| KZ312_RS26540 (KZ312_26540) | 129468..131426 | + | 1959 | WP_141218937.1 | ParB/RepB/Spo0J family partition protein | - |
| KZ312_RS26545 (KZ312_26545) | 131481..131915 | + | 435 | WP_134233614.1 | conjugation system SOS inhibitor PsiB | - |
| KZ312_RS26550 (KZ312_26550) | 131912..132631 | + | 720 | WP_219790168.1 | plasmid SOS inhibition protein A | - |
| KZ312_RS26555 (KZ312_26555) | 132628..133224 | + | 597 | WP_029391986.1 | hypothetical protein | - |
| KZ312_RS26560 (KZ312_26560) | 133689..134189 | + | 501 | WP_000117633.1 | antirestriction protein ArdA | - |
| KZ312_RS26565 (KZ312_26565) | 134191..134802 | - | 612 | WP_219790170.1 | hypothetical protein | - |
| KZ312_RS26570 (KZ312_26570) | 134920..135354 | + | 435 | WP_000218850.1 | hypothetical protein | - |
| KZ312_RS26575 (KZ312_26575) | 135447..135713 | + | 267 | WP_021580018.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|