MGE detailed information
MGE type: Conjugative plasmid MGE length: 144481 bp
Accession: NZ_CP080076 Location: 1..144481 Organism: Escherichia coli strain 19SZHZ663Rt Replicon: plasmid p663Rt_IncR
Accession: NZ_CP080076 Location: 1..144481 Organism: Escherichia coli strain 19SZHZ663Rt Replicon: plasmid p663Rt_IncR
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KZO16_RS22645 (1) | 1..858 | + | 858 | WP_039002220.1 | incFII family plasmid replication initiator RepA | - |
| KZO16_RS22650 (1798) | 1798..2451 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| KZO16_RS22655 (2544) | 2544..2801 | + | 258 | WP_249776062.1 | type II toxin-antitoxin system antitoxin PemI | - |
| KZO16_RS22660 (2734) | 2734..3135 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| KZO16_RS22665 (3420) | 3420..4727 | + | 1308 | WP_094336907.1 | DUF262 domain-containing protein | - |
| KZO16_RS22675 (6020) | 6020..6118 | + | 99 | Protein_6 | IS1 family transposase | - |
| KZO16_RS22680 (6268) | 6268..6564 | - | 297 | Protein_7 | serine hydrolase | - |
| KZO16_RS22685 (6629) | 6629..6940 | + | 312 | Protein_8 | IS6-like element IS26 family transposase | - |
| KZO16_RS22690 (6995) | 6995..7699 | - | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| KZO16_RS22695 (7874) | 7874..8122 | + | 249 | WP_000618110.1 | DinI-like family protein | - |
| KZO16_RS22700 (8119) | 8119..8556 | + | 438 | WP_000109071.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| KZO16_RS22705 (8556) | 8556..9827 | + | 1272 | WP_000457518.1 | Y-family DNA polymerase | - |
| KZO16_RS22710 (9832) | 9832..10224 | - | 393 | WP_000340829.1 | plasmid partitioning/stability family protein | - |
| KZO16_RS22715 (10229) | 10229..11200 | - | 972 | WP_001103690.1 | plasmid segregation protein ParM | - |
| KZO16_RS22720 (11422) | 11422..12066 | + | 645 | WP_000633913.1 | division plane positioning ATPase MipZ | - |
| KZO16_RS22725 (12060) | 12060..12335 | + | 276 | WP_000239529.1 | hypothetical protein | - |
| KZO16_RS22730 (12487) | 12487..13263 | - | 777 | Protein_17 | site-specific integrase | - |
| KZO16_RS22735 (13260) | 13260..13766 | - | 507 | WP_001505085.1 | hypothetical protein | - |
| KZO16_RS22740 (13757) | 13757..14461 | + | 705 | WP_065304467.1 | IS6-like element IS26 family transposase | - |
| KZO16_RS22745 (14610) | 14610..15935 | - | 1326 | WP_021512928.1 | reactive chlorine resistance oxidoreductase RclA | - |
| KZO16_RS22750 (16045) | 16045..16742 | + | 698 | WP_114161604.1 | IS1 family transposase IS1R | Transposase |
| KZO16_RS22755 (16843) | 16843..17124 | - | 282 | WP_000639434.1 | hypothetical protein | - |
| KZO16_RS22760 (17226) | 17226..18119 | - | 894 | Protein_23 | IS3 family transposase ISEhe3 | Transposase |
| KZO16_RS22765 (18187) | 18187..19005 | + | 819 | Protein_24 | IS30 family transposase IS30D | Transposase |
| KZO16_RS22770 (19048) | 19048..19530 | - | 483 | Protein_25 | IS3 family transposase | - |
| KZO16_RS22775 (19596) | 19596..20300 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| KZO16_RS22780 (20306) | 20306..20614 | + | 309 | WP_223419848.1 | hypothetical protein | - |
| KZO16_RS22785 (20617) | 20617..21408 | - | 792 | WP_000034420.1 | Dihydropteroate synthase | ARG |
| KZO16_RS22790 (21877) | 21877..22122 | - | 246 | WP_001354008.1 | GrpB family protein | - |
| KZO16_RS22795 (22160) | 22160..23023 | - | 864 | WP_000612791.1 | SDR family oxidoreductase | - |
| KZO16_RS22800 (23169) | 23169..23426 | - | 258 | Protein_31 | hypothetical protein | - |
| KZO16_RS22805 (23481) | 23481..24185 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| KZO16_RS22810 (24251) | 24251..24472 | + | 222 | Protein_33 | tyrosine-type recombinase/integrase | - |
| KZO16_RS22815 (24677) | 24677..25753 | + | 1077 | Protein_34 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| KZO16_RS22820 (25900) | 25900..26760 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| KZO16_RS22825 (26943) | 26943..27500 | - | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| KZO16_RS22830 (27664) | 27664..30669 | + | 3006 | WP_001143760.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| KZO16_RS22835 (30712) | 30712..31727 | - | 1016 | Protein_38 | IS3 family transposase ISEc36 | Transposase |
| KZO16_RS22840 (32122) | 32122..32778 | + | 657 | WP_001516695.1 | Pentapeptide repeat protein | ARG |
| KZO16_RS22845 (33097) | 33097..33525 | - | 429 | Protein_40 | Tn3 family transposase TnpR_ISMex22 | Transposase |
| KZO16_RS22850 (33558) | 33558..34418 | - | 861 | Protein_41 | ISKra4 family transposase ISKpn19 | Transposase |
| KZO16_RS22855 (34473) | 34473..35177 | + | 705 | WP_001067858.1 | ISKra4 family transposase ISKpn19 | Transposase |
| KZO16_RS22860 (35229) | 35229..35675 | + | 447 | Protein_43 | IS6-like element IS26 family transposase | - |
| KZO16_RS22865 (35750) | 35750..36136 | + | 387 | WP_001039464.1 | plasmid stabilization protein StbA | - |
| KZO16_RS22870 (36276) | 36276..37244 | - | 969 | WP_162722054.1 | IS5 family transposase IS903B | Transposase |
| KZO16_RS22875 (37687) | 37687..38394 | + | 708 | Protein_46 | translesion error-prone DNA polymerase V subunit UmuC | - |
| KZO16_RS22880 (38476) | 38476..39450 | - | 975 | WP_000064120.1 | ParB family protein | - |
| KZO16_RS22885 (39450) | 39450..40655 | - | 1206 | WP_000368714.1 | AAA family ATPase | - |
| KZO16_RS22890 (41070) | 41070..41339 | + | 270 | WP_000339857.1 | hypothetical protein | - |
| KZO16_RS22895 (41660) | 41660..42526 | - | 867 | WP_004118283.1 | replication initiation protein | - |
| KZO16_RS22900 (43061) | 43061..43165 | + | 105 | WP_032409716.1 | hypothetical protein | - |
| KZO16_RS22905 (43294) | 43294..43551 | + | 258 | WP_000764642.1 | hypothetical protein | - |
| KZO16_RS22910 (43609) | 43609..44385 | - | 777 | WP_000015958.1 | site-specific integrase | - |
| KZO16_RS22915 (44382) | 44382..45125 | - | 744 | WP_000129823.1 | hypothetical protein | - |
| KZO16_RS22920 (45176) | 45176..45526 | - | 351 | WP_004118279.1 | hypothetical protein | - |
| KZO16_RS22925 (46094) | 46094..47068 | - | 975 | WP_001148756.1 | sensor domain-containing diguanylate cyclase | - |
| KZO16_RS22930 (47705) | 47705..48613 | + | 909 | Protein_57 | HNH endonuclease | - |
| KZO16_RS22935 (49001) | 49001..49351 | - | 351 | WP_000694953.1 | DUF305 domain-containing protein | - |
| KZO16_RS22940 (49495) | 49495..49926 | - | 432 | WP_000790483.1 | silver-binding protein SilE | - |
| KZO16_RS22945 (50177) | 50177..51652 | - | 1476 | WP_000555737.1 | copper/silver sensor histidine kinase SilS | - |
| KZO16_RS22950 (51645) | 51645..52325 | - | 681 | WP_000697969.1 | Transcriptional regulatory protein CusR | VF |
| KZO16_RS22955 (52515) | 52515..53900 | + | 1386 | WP_000475512.1 | Cation efflux system protein CusC | VF |
| KZO16_RS22960 (53928) | 53928..54281 | + | 354 | WP_001246155.1 | cation efflux system protein CusF | - |
| KZO16_RS22965 (54395) | 54395..55687 | + | 1293 | WP_001398209.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| KZO16_RS22970 (55698) | 55698..58844 | + | 3147 | WP_000574035.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| KZO16_RS22975 (58931) | 58931..59371 | + | 441 | WP_000758221.1 | DUF411 domain-containing protein | - |
| KZO16_RS22980 (59469) | 59469..61946 | + | 2478 | WP_011251358.1 | Ag(+)-translocating P-type ATPase SilP | - |
| KZO16_RS22985 (61987) | 61987..62184 | + | 198 | WP_000843501.1 | DUF2933 domain-containing protein | - |
| KZO16_RS22990 (62218) | 62218..62949 | - | 732 | WP_094336930.1 | peptidoglycan DD-metalloendopeptidase family protein | - |
| KZO16_RS23000 (63985) | 63985..66690 | + | 2706 | WP_016240421.1 | HTH-type transcriptional regulator MalT | VF |
| KZO16_RS23005 (66733) | 66733..67086 | - | 354 | Protein_72 | RNA 3'-terminal phosphate cyclase | - |
| KZO16_RS23010 (67494) | 67494..68438 | - | 945 | Protein_73 | IS110 family transposase IS5708 | Transposase |
| KZO16_RS23015 (68506) | 68506..69210 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| KZO16_RS23020 (69264) | 69264..69731 | + | 468 | Protein_75 | conjugal transfer protein | - |
| KZO16_RS23025 (69976) | 69976..70092 | + | 117 | WP_001814923.1 | tetracycline resistance determinant leader peptide | - |
| KZO16_RS23030 (70108) | 70108..72027 | + | 1920 | WP_025989258.1 | Tetracycline resistance protein TetM from transposon TnFO1 | VF |
| KZO16_RS23035 (72146) | 72146..72313 | + | 168 | WP_000336323.1 | cysteine-rich KTR domain-containing protein | - |
| KZO16_RS23040 (72574) | 72574..73206 | + | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| KZO16_RS23045 (73453) | 73453..73785 | - | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| KZO16_RS23050 (73908) | 73908..74746 | - | 839 | Protein_81 | Streptomycin 3''-adenylyltransferase | ARG |
| KZO16_RS23055 (74839) | 74839..76098 | - | 1260 | WP_000095725.1 | Bicyclomycin resistance protein | ARG |
| KZO16_RS23060 (76313) | 76313..77151 | - | 839 | Protein_83 | Streptomycin 3''-adenylyltransferase | ARG |
| KZO16_RS23065 (77157) | 77157..77447 | - | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| KZO16_RS23070 (77559) | 77559..78056 | - | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| KZO16_RS23075 (78201) | 78201..79214 | + | 1014 | WP_000845039.1 | IS91 family transposase ISAzo26 | Transposase |
| KZO16_RS23080 (79417) | 79417..79767 | + | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| KZO16_RS23085 (79893) | 79893..80453 | + | 561 | WP_000147567.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| KZO16_RS23090 (80456) | 80456..83407 | + | 2952 | WP_015344976.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| KZO16_RS23095 (83341) | 83341..83775 | + | 435 | WP_249776061.1 | hypothetical protein | - |
| KZO16_RS23100 (83809) | 83809..84513 | - | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| KZO16_RS23105 (84693) | 84693..85277 | + | 585 | WP_000477040.1 | fimbrial protein | - |
| KZO16_RS23110 (85330) | 85330..86022 | + | 693 | WP_001223973.1 | putative fimbrial chaperone YehC | VF |
| KZO16_RS23115 (86038) | 86038..88530 | + | 2493 | WP_000782716.1 | Outer membrane usher protein YehB | VF |
| KZO16_RS23120 (88546) | 88546..89610 | + | 1065 | WP_000946279.1 | fimbrial protein | - |
| KZO16_RS23125 (89760) | 89760..90464 | + | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| KZO16_RS23130 (90831) | 90831..91733 | + | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| KZO16_RS23135 (91730) | 91730..92041 | + | 312 | WP_011254640.1 | hypothetical protein | - |
| KZO16_RS23140 (92118) | 92118..92801 | + | 684 | WP_000086185.1 | DNA methylase | - |
| KZO16_RS23145 (92802) | 92802..93023 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| KZO16_RS23150 (92953) | 92953..93471 | + | 519 | WP_123325260.1 | DUF1380 family protein | - |
| KZO16_RS23155 (93522) | 93522..94298 | + | 777 | WP_001753849.1 | hypothetical protein | - |
| KZO16_RS23160 (94715) | 94715..95140 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| KZO16_RS23165 (95187) | 95187..95609 | + | 423 | WP_000271753.1 | DUF1380 family protein | - |
| KZO16_RS23170 (95606) | 95606..95797 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| KZO16_RS23175 (96832) | 96832..97062 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| KZO16_RS23180 (97114) | 97114..98475 | + | 1362 | WP_038999961.1 | DUF3560 domain-containing protein | - |
| KZO16_RS23185 (98523) | 98523..99086 | + | 564 | WP_001315564.1 | class I SAM-dependent methyltransferase | - |
| KZO16_RS23190 (99238) | 99238..99465 | + | 228 | WP_071961421.1 | hypothetical protein | - |
| KZO16_RS23195 (99706) | 99706..99912 | + | 207 | WP_000275853.1 | hypothetical protein | - |
| KZO16_RS23200 (99938) | 99938..100477 | + | 540 | WP_032332913.1 | single-stranded DNA-binding protein | - |
| KZO16_RS23205 (100534) | 100534..100767 | + | 234 | WP_000005987.1 | DUF905 family protein | - |
| KZO16_RS23210 (100832) | 100832..102790 | + | 1959 | WP_223419851.1 | ParB/RepB/Spo0J family partition protein | - |
| KZO16_RS23215 (102845) | 102845..103279 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| KZO16_RS23220 (103276) | 103276..104038 | + | 763 | Protein_115 | plasmid SOS inhibition protein A | - |
| KZO16_RS23225 (104007) | 104007..104195 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - (104007) | 104007..104231 | + | 225 | NuclAT_0 | - | - |
| - (104007) | 104007..104231 | + | 225 | NuclAT_0 | - | - |
| - (104007) | 104007..104231 | + | 225 | NuclAT_0 | - | - |
| - (104007) | 104007..104231 | + | 225 | NuclAT_0 | - | - |
| KZO16_RS23230 (104217) | 104217..104366 | + | 150 | Protein_117 | plasmid maintenance protein Mok | - |
| KZO16_RS23235 (104308) | 104308..104433 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| KZO16_RS23240 (104653) | 104653..104883 | + | 231 | WP_001426396.1 | hypothetical protein | - |
| KZO16_RS23245 (104881) | 104881..105054 | - | 174 | Protein_120 | hypothetical protein | - |
| KZO16_RS23250 (105124) | 105124..105384 | + | 261 | WP_042046747.1 | hypothetical protein | - |
| KZO16_RS23255 (105478) | 105478..106482 | - | 1005 | WP_024257664.1 | IS110 family transposase IS1663 | Transposase |
| KZO16_RS23260 (106578) | 106578..107003 | + | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| KZO16_RS23265 (107000) | 107000..107350 | + | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| KZO16_RS23270 (107381) | 107381..108994 | + | 1614 | WP_000080200.1 | IS66 family transposase ISEc23 | Transposase |
| KZO16_RS23275 (109273) | 109273..109560 | + | 288 | WP_000107535.1 | hypothetical protein | - |
| KZO16_RS23280 (109682) | 109682..110503 | + | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| KZO16_RS23285 (110800) | 110800..111390 | - | 591 | WP_283808063.1 | hypothetical protein | VF |
| KZO16_RS23290 (111723) | 111723..112106 | + | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| KZO16_RS23295 (112293) | 112293..112982 | + | 690 | WP_039002187.1 | conjugal transfer transcriptional regulator TraJ | - |
| KZO16_RS23300 (113075) | 113075..113476 | + | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| KZO16_RS23305 (113509) | 113509..113871 | + | 363 | WP_000994784.1 | type IV conjugative transfer system pilin TraA | - |
| KZO16_RS23310 (113876) | 113876..114187 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| KZO16_RS23315 (114209) | 114209..114775 | + | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| KZO16_RS23320 (114762) | 114762..115490 | + | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| KZO16_RS23325 (115490) | 115490..116917 | + | 1428 | WP_000146690.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| KZO16_RS23330 (116907) | 116907..117494 | + | 588 | WP_000002772.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| KZO16_RS23335 (117481) | 117481..117801 | + | 321 | WP_001057285.1 | conjugal transfer protein TrbD | - |
| KZO16_RS23340 (117798) | 117798..118313 | + | 516 | WP_000724019.1 | type IV conjugative transfer system lipoprotein TraV | - |
| KZO16_RS23345 (118448) | 118448..118669 | + | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| KZO16_RS23350 (118829) | 118829..121456 | + | 2628 | WP_001064265.1 | type IV secretion system protein TraC | - |
| KZO16_RS23355 (121453) | 121453..121839 | + | 387 | WP_039002198.1 | type-F conjugative transfer system protein TrbI | - |
| KZO16_RS23360 (121836) | 121836..122468 | + | 633 | WP_001749440.1 | type-F conjugative transfer system protein TraW | - |
| KZO16_RS23365 (122465) | 122465..123457 | + | 993 | WP_023148235.1 | conjugal transfer pilus assembly protein TraU | - |
| KZO16_RS23370 (123466) | 123466..124104 | + | 639 | WP_000777691.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| KZO16_RS23375 (124101) | 124101..125909 | + | 1809 | WP_000821844.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| KZO16_RS23380 (125936) | 125936..126196 | + | 261 | WP_000864348.1 | conjugal transfer protein TrbE | - |
| KZO16_RS23385 (126189) | 126189..126932 | + | 744 | WP_039002205.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| KZO16_RS23390 (127093) | 127093..127329 | + | 237 | WP_054377141.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| KZO16_RS23395 (127316) | 127316..127861 | + | 546 | WP_000052613.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| KZO16_RS23400 (127791) | 127791..128153 | + | 363 | WP_001443292.1 | P-type conjugative transfer protein TrbJ | - |
| KZO16_RS23405 (128153) | 128153..129526 | + | 1374 | WP_170926237.1 | conjugal transfer pilus assembly protein TraH | - |
| KZO16_RS23410 (129523) | 129523..132345 | + | 2823 | WP_001007048.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| KZO16_RS23415 (132360) | 132360..132863 | + | 504 | WP_000605510.1 | hypothetical protein | - |
| KZO16_RS23420 (132895) | 132895..133626 | + | 732 | WP_000850424.1 | conjugal transfer complement resistance protein TraT | - |
| KZO16_RS23425 (133879) | 133879..136068 | + | 2190 | WP_039002212.1 | type IV conjugative transfer system coupling protein TraD | - |
| KZO16_RS23430 (136068) | 136068..141338 | + | 5271 | WP_054377139.1 | Multifunctional conjugation protein TraI | Relaxase |
| KZO16_RS23435 (141358) | 141358..142101 | + | 744 | WP_039002216.1 | conjugal transfer pilus acetylase TraX | - |
| KZO16_RS23440 (142156) | 142156..142716 | + | 561 | WP_000139310.1 | fertility inhibition protein FinO | - |
| KZO16_RS23445 (142850) | 142850..143062 | + | 213 | WP_001541896.1 | ANR family transcriptional regulator | - |
| - (143404) | 143404..143465 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (143404) | 143404..143465 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (143404) | 143404..143465 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (143404) | 143404..143465 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| KZO16_RS23450 (143509) | 143509..143658 | + | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| KZO16_RS23455 (143926) | 143926..144183 | + | 258 | WP_001541895.1 | replication regulatory protein RepA | - |
| KZO16_RS23460 (144286) | 144286..144469 | + | 184 | Protein_163 | plasmid copy control protein CopA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|