MGE detailed information
MGE type: Conjugative plasmid MGE length: 78128 bp
Accession: NZ_CP076520 Location: 1..78128 Organism: Klebsiella pneumoniae strain K186 Replicon: plasmid pK186_2
Accession: NZ_CP076520 Location: 1..78128 Organism: Klebsiella pneumoniae strain K186 Replicon: plasmid pK186_2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KNW01_RS27430 (1) | 1..858 | + | 858 | WP_000130646.1 | incFII family plasmid replication initiator RepA | - |
| KNW01_RS27435 (1797) | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| KNW01_RS27440 (2543) | 2543..2800 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| KNW01_RS27445 (2733) | 2733..3134 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| KNW01_RS27450 (3383) | 3383..3798 | + | 416 | Protein_4 | IS1 family transposase IS1R | Transposase |
| KNW01_RS27455 (3834) | 3834..4325 | - | 492 | Protein_5 | Tn3 family transposase TnpA_Tn3 | Transposase |
| KNW01_RS27460 (4391) | 4391..5095 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KNW01_RS27465 (5160) | 5160..5753 | - | 594 | Protein_7 | Multifunctional conjugation protein TraI | Relaxase |
| KNW01_RS27470 (5753) | 5753..7123 | - | 1371 | Protein_8 | type IV secretion system DNA-binding domain-containing protein | - |
| KNW01_RS27475 (7296) | 7296..8495 | - | 1200 | WP_000948429.1 | IS91 family transposase ISSbo1 | Transposase |
| KNW01_RS27480 (8505) | 8505..8693 | - | 189 | WP_000957857.1 | hypothetical protein | - |
| KNW01_RS27485 (8708) | 8708..9088 | - | 381 | WP_216269671.1 | DGQHR domain-containing protein | - |
| KNW01_RS27490 (9141) | 9141..9518 | - | 378 | WP_033547333.1 | hypothetical protein | - |
| KNW01_RS27495 (10056) | 10056..10496 | + | 441 | WP_113248404.1 | translesion error-prone DNA polymerase V autoproteolytic subunit MucA | - |
| KNW01_RS27500 (10484) | 10484..11749 | + | 1266 | WP_052990778.1 | translesion error-prone DNA polymerase V subunit MucB | - |
| KNW01_RS27505 (11900) | 11900..12685 | + | 786 | WP_216269673.1 | SprT-like domain-containing protein | - |
| KNW01_RS27510 (12701) | 12701..12922 | - | 222 | WP_063267574.1 | hypothetical protein | - |
| KNW01_RS27515 (12935) | 12935..13264 | - | 330 | WP_052990780.1 | TrfB-related DNA-binding protein | - |
| KNW01_RS27520 (14296) | 14296..14496 | + | 201 | WP_074163873.1 | hypothetical protein | - |
| KNW01_RS27525 (14546) | 14546..15427 | - | 882 | WP_052990694.1 | replication protein RepA | - |
| KNW01_RS27530 (15430) | 15430..16029 | - | 600 | WP_063267573.1 | Tn3 family transposase TnpR_ISPa38 | Transposase |
| KNW01_RS27535 (16032) | 16032..16751 | - | 720 | WP_113555032.1 | Type IV secretion system protein PtlF | VF |
| KNW01_RS27540 (16863) | 16863..17567 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KNW01_RS27545 (18332) | 18332..18566 | + | 235 | Protein_23 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| KNW01_RS27550 (18694) | 18694..18975 | + | 282 | WP_001333089.1 | hypothetical protein | - |
| KNW01_RS27555 (19098) | 19098..19448 | - | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| KNW01_RS27560 (19451) | 19451..20413 | - | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| KNW01_RS27565 (20560) | 20560..20853 | + | 294 | WP_032146011.1 | hypothetical protein | - |
| KNW01_RS27570 (20930) | 20930..21613 | + | 684 | WP_000085883.1 | DNA methylase | - |
| KNW01_RS27575 (21614) | 21614..21835 | + | 222 | WP_001104881.1 | hypothetical protein | - |
| KNW01_RS27580 (21849) | 21849..22283 | + | 435 | WP_000274503.1 | DUF1380 family protein | - |
| KNW01_RS27585 (22334) | 22334..23110 | + | 777 | WP_001383963.1 | hypothetical protein | - |
| KNW01_RS27590 (23528) | 23528..23953 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| KNW01_RS27595 (24000) | 24000..24422 | + | 423 | WP_000271762.1 | DUF1380 family protein | - |
| KNW01_RS27600 (24419) | 24419..24610 | + | 192 | WP_001027493.1 | hypothetical protein | - |
| KNW01_RS27605 (25648) | 25648..25878 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| KNW01_RS27610 (25930) | 25930..27291 | + | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| KNW01_RS27615 (27338) | 27338..27901 | + | 564 | WP_001298559.1 | class I SAM-dependent methyltransferase | - |
| KNW01_RS28295 (27987) | 27987..28442 | - | 456 | Protein_38 | hypothetical protein | - |
| KNW01_RS27620 (28744) | 28744..29271 | + | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| KNW01_RS27625 (29329) | 29329..29562 | + | 234 | WP_000006003.1 | DUF905 family protein | - |
| KNW01_RS27630 (29623) | 29623..31646 | + | 2024 | Protein_41 | ParB/RepB/Spo0J family partition protein | - |
| KNW01_RS27635 (31715) | 31715..32149 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| KNW01_RS27640 (32146) | 32146..32865 | + | 720 | WP_001276217.1 | plasmid SOS inhibition protein A | - |
| - (32877) | 32877..33101 | + | 225 | NuclAT_0 | - | - |
| - (32877) | 32877..33101 | + | 225 | NuclAT_0 | - | - |
| - (32877) | 32877..33101 | + | 225 | NuclAT_0 | - | - |
| - (32877) | 32877..33101 | + | 225 | NuclAT_0 | - | - |
| KNW01_RS28300 (33087) | 33087..33236 | + | 150 | Protein_44 | plasmid maintenance protein Mok | - |
| KNW01_RS27645 (33178) | 33178..33303 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| KNW01_RS27650 (33622) | 33622..33918 | - | 297 | Protein_46 | hypothetical protein | - |
| KNW01_RS27655 (34218) | 34218..34514 | + | 297 | WP_001272251.1 | hypothetical protein | - |
| KNW01_RS27660 (34625) | 34625..35446 | + | 822 | WP_001234445.1 | DUF932 domain-containing protein | - |
| KNW01_RS27665 (35743) | 35743..36333 | - | 591 | WP_000252683.1 | hypothetical protein | VF |
| KNW01_RS27670 (36668) | 36668..37051 | + | 384 | WP_001354030.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| KNW01_RS27675 (37245) | 37245..37916 | + | 672 | WP_000283561.1 | conjugal transfer transcriptional regulator TraJ | - |
| KNW01_RS27680 (38053) | 38053..38280 | + | 228 | WP_000089263.1 | conjugal transfer relaxosome protein TraY | - |
| KNW01_RS27685 (38313) | 38313..38672 | + | 360 | WP_202150128.1 | type IV conjugative transfer system pilin TraA | - |
| KNW01_RS27690 (38687) | 38687..38998 | + | 312 | WP_000012113.1 | type IV conjugative transfer system protein TraL | - |
| KNW01_RS27695 (39020) | 39020..39586 | + | 567 | WP_000399780.1 | type IV conjugative transfer system protein TraE | - |
| KNW01_RS27700 (39573) | 39573..40301 | + | 729 | WP_001230772.1 | type-F conjugative transfer system secretin TraK | - |
| KNW01_RS27705 (40301) | 40301..41752 | + | 1452 | WP_216269669.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| KNW01_RS27710 (41742) | 41742..42308 | + | 567 | WP_000896599.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| KNW01_RS27715 (42295) | 42295..42615 | + | 321 | WP_012881128.1 | conjugal transfer protein TrbD | - |
| KNW01_RS27720 (42612) | 42612..43127 | + | 516 | WP_000809881.1 | type IV conjugative transfer system lipoprotein TraV | - |
| KNW01_RS27725 (43262) | 43262..43483 | + | 222 | WP_001278683.1 | conjugal transfer protein TraR | - |
| KNW01_RS27730 (43476) | 43476..43952 | + | 477 | WP_012881127.1 | hypothetical protein | - |
| KNW01_RS27735 (44051) | 44051..44269 | + | 219 | WP_000556745.1 | hypothetical protein | - |
| KNW01_RS27740 (44297) | 44297..44644 | + | 348 | WP_000836682.1 | hypothetical protein | - |
| KNW01_RS27745 (44770) | 44770..47400 | + | 2631 | WP_000069772.1 | type IV secretion system protein TraC | - |
| KNW01_RS27750 (47397) | 47397..47783 | + | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| KNW01_RS27755 (47780) | 47780..48412 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| KNW01_RS27760 (48409) | 48409..49401 | + | 993 | WP_000830849.1 | conjugal transfer pilus assembly protein TraU | - |
| KNW01_RS27765 (49431) | 49431..49736 | + | 306 | WP_000224418.1 | hypothetical protein | - |
| KNW01_RS27770 (49745) | 49745..50383 | + | 639 | WP_012881126.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| KNW01_RS27775 (50380) | 50380..52230 | + | 1851 | WP_000821856.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| KNW01_RS27780 (52257) | 52257..52514 | + | 258 | WP_000864353.1 | conjugal transfer protein TrbE | - |
| KNW01_RS27785 (52507) | 52507..53190 | + | 684 | Protein_73 | type-F conjugative transfer system pilin assembly protein TraF | - |
| KNW01_RS27790 (53243) | 53243..53947 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KNW01_RS27795 (54073) | 54073..54828 | - | 756 | WP_012372818.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase | ARG |
| KNW01_RS27800 (54998) | 54998..55093 | - | 96 | Protein_76 | class A beta-lactamase | - |
| KNW01_RS27805 (55147) | 55147..55851 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KNW01_RS27810 (55916) | 55916..56125 | + | 210 | Protein_78 | IS1 family transposase | - |
| KNW01_RS28405 (56617) | 56617..56700 | + | 84 | WP_272056275.1 | DinQ-like type I toxin DqlB | - |
| KNW01_RS28410 (57261) | 57261..57356 | + | 96 | WP_000609146.1 | DinQ-like type I toxin DqlB | - |
| KNW01_RS27815 (57423) | 57423..57602 | + | 180 | WP_000347021.1 | hypothetical protein | - |
| KNW01_RS27820 (57718) | 57718..58362 | - | 645 | WP_000203199.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| KNW01_RS27825 (58657) | 58657..59277 | + | 621 | WP_000864788.1 | ParA family protein | - |
| KNW01_RS27830 (59329) | 59329..59559 | + | 231 | WP_000051066.1 | plasmid partition protein ParG | - |
| KNW01_RS27835 (59983) | 59983..61047 | + | 1065 | WP_012291478.1 | ParA family protein | - |
| KNW01_RS27840 (61585) | 61585..61938 | - | 354 | WP_024129958.1 | DNA distortion polypeptide 3 | - |
| KNW01_RS27845 (62075) | 62075..62521 | - | 447 | WP_001074384.1 | hypothetical protein | - |
| KNW01_RS27850 (62525) | 62525..63367 | - | 843 | WP_000435064.1 | replication initiation protein | - |
| KNW01_RS27855 (63388) | 63388..64227 | - | 840 | WP_024129959.1 | replication initiation protein | - |
| KNW01_RS27860 (65462) | 65462..65713 | + | 252 | WP_000121743.1 | plasmid stabilization protein | Antitoxin Detail |
| KNW01_RS27865 (65703) | 65703..65984 | + | 282 | WP_000220561.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| KNW01_RS27870 (66223) | 66223..66315 | - | 93 | Protein_92 | IS6 family transposase | - |
| KNW01_RS27875 (66481) | 66481..67680 | - | 1200 | WP_000948429.1 | IS91 family transposase ISSbo1 | Transposase |
| KNW01_RS27880 (67690) | 67690..67878 | - | 189 | WP_000957857.1 | hypothetical protein | - |
| KNW01_RS27885 (67994) | 67994..68788 | - | 795 | Protein_95 | TraD N-terminal domain-containing protein | - |
| KNW01_RS27890 (68839) | 68839..69576 | - | 738 | WP_000199905.1 | hypothetical protein | - |
| KNW01_RS27895 (69779) | 69779..70510 | - | 732 | WP_000782451.1 | conjugal transfer complement resistance protein TraT | - |
| KNW01_RS27900 (70559) | 70559..71044 | - | 486 | WP_000605870.1 | hypothetical protein | - |
| KNW01_RS27905 (71060) | 71060..73882 | - | 2823 | WP_001007039.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| KNW01_RS27910 (73879) | 73879..75261 | - | 1383 | WP_001309243.1 | conjugal transfer pilus assembly protein TraH | - |
| KNW01_RS27915 (75239) | 75239..75631 | - | 393 | WP_000660699.1 | F-type conjugal transfer protein TrbF | - |
| KNW01_RS27920 (75612) | 75612..75743 | - | 132 | Protein_102 | conjugal transfer protein TrbJ | - |
| KNW01_RS27925 (75796) | 75796..76500 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KNW01_RS27930 (76547) | 76547..76702 | + | 156 | Protein_104 | Hha/YmoA family nucleoid-associated regulatory protein | - |
| KNW01_RS27935 (76740) | 76740..77330 | + | 591 | WP_000766807.1 | DUF2726 domain-containing protein | - |
| KNW01_RS27940 (77570) | 77570..77824 | + | 255 | WP_000083830.1 | replication regulatory protein RepA | - |
| KNW01_RS28305 (77931) | 77931..78116 | + | 186 | WP_012615301.1 | plasmid copy control protein CopA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|