MGE detailed information
MGE type: Conjugative plasmid MGE length: 129015 bp
Accession: NZ_CP074032 Location: 1..129015 Organism: Escherichia coli strain PK12 Replicon: plasmid pYLPK12
Accession: NZ_CP074032 Location: 1..129015 Organism: Escherichia coli strain PK12 Replicon: plasmid pYLPK12
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KFU67_RS24300 (1) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| KFU67_RS24305 (1263) | 1263..2003 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| KFU67_RS24310 (2124) | 2124..2312 | - | 189 | WP_001312821.1 | hypothetical protein | - |
| KFU67_RS24315 (2686) | 2686..3588 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| KFU67_RS24320 (3657) | 3657..4766 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| KFU67_RS24325 (5199) | 5199..6152 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| KFU67_RS24330 (7449) | 7449..7628 | - | 180 | Protein_6 | transposase | - |
| KFU67_RS24335 (7767) | 7767..8980 | + | 1214 | WP_162842477.1 | IS3 family transposase IS629 | Transposase |
| KFU67_RS24340 (9128) | 9128..9396 | - | 269 | Protein_8 | IS3 family transposase ISLad1 | Transposase |
| KFU67_RS24345 (9453) | 9453..10150 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| KFU67_RS24350 (10167) | 10167..10364 | - | 198 | Protein_10 | colicin V | - |
| KFU67_RS24355 (10342) | 10342..10578 | - | 237 | WP_014640552.1 | colicin V immunity protein | - |
| KFU67_RS24360 (11120) | 11120..11323 | - | 204 | Protein_12 | hypothetical protein | - |
| KFU67_RS24365 (11496) | 11496..11663 | + | 168 | Protein_13 | colicin-B | - |
| KFU67_RS24370 (11681) | 11681..12208 | - | 528 | WP_000203272.1 | colicin B immunity protein | - |
| KFU67_RS24375 (12452) | 12452..13267 | + | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| KFU67_RS24380 (13317) | 13317..13670 | - | 354 | WP_000864812.1 | colicin M immunity protein | - |
| KFU67_RS24385 (13848) | 13848..14639 | - | 792 | WP_000016493.1 | site-specific integrase | - |
| KFU67_RS24390 (14636) | 14636..15325 | - | 690 | WP_000796228.1 | hypothetical protein | - |
| KFU67_RS24395 (15369) | 15369..15719 | - | 351 | WP_000493379.1 | hypothetical protein | - |
| KFU67_RS24400 (16264) | 16264..17352 | + | 1089 | WP_000952217.1 | transcriptional repressor PifC | - |
| KFU67_RS24405 (17354) | 17354..19579 | + | 2226 | WP_000698737.1 | P-loop NTPase fold protein | - |
| KFU67_RS24410 (19629) | 19629..20528 | - | 900 | WP_000963206.1 | nucleotide-binding protein | - |
| KFU67_RS24415 (20518) | 20518..20808 | - | 291 | WP_000111771.1 | hypothetical protein | - |
| KFU67_RS24420 (21104) | 21104..21334 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| KFU67_RS24425 (21331) | 21331..21747 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| KFU67_RS24430 (21909) | 21909..24047 | - | 2139 | WP_000350638.1 | AAA family ATPase | - |
| KFU67_RS24435 (24401) | 24401..24658 | + | 258 | WP_000343085.1 | hypothetical protein | - |
| KFU67_RS24440 (24658) | 24658..25248 | + | 591 | WP_000194575.1 | hypothetical protein | - |
| KFU67_RS24445 (25511) | 25511..26971 | + | 1461 | WP_202745975.1 | AAA family ATPase | - |
| KFU67_RS24450 (27259) | 27259..27876 | + | 618 | WP_000521603.1 | ProQ/FINO family protein | - |
| KFU67_RS24455 (28274) | 28274..29536 | + | 1263 | WP_000608644.1 | IS1380 family transposase ISEcp1 | Transposase |
| KFU67_RS24460 (29792) | 29792..30667 | + | 876 | WP_015387340.1 | Beta-lactamase CTX-M-1 | ARG |
| KFU67_RS24465 (30714) | 30714..31007 | - | 294 | WP_116961751.1 | WbuC family cupin fold metalloprotein | - |
| KFU67_RS24470 (31224) | 31224..32303 | - | 1080 | WP_001089727.1 | permease | - |
| KFU67_RS24475 (32408) | 32408..32731 | + | 324 | WP_001175594.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| KFU67_RS24480 (32892) | 32892..33212 | + | 321 | Protein_36 | NAD(P)H-dependent oxidoreductase | - |
| KFU67_RS24485 (33265) | 33265..33969 | - | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| KFU67_RS24490 (34035) | 34035..35549 | + | 1515 | Protein_38 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| KFU67_RS24495 (35607) | 35607..35849 | + | 243 | WP_000844627.1 | transposase | - |
| KFU67_RS24500 (35881) | 35881..36531 | - | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| KFU67_RS24505 (36637) | 36637..37836 | + | 1200 | WP_077248803.1 | Tetracycline resistance protein, class C | ARG |
| KFU67_RS24510 (37868) | 37868..38752 | - | 885 | WP_000058717.1 | EamA family transporter | - |
| KFU67_RS24515 (38890) | 38890..39282 | - | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| KFU67_RS24520 (39286) | 39286..40866 | + | 1581 | Protein_44 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| KFU67_RS24525 (40917) | 40917..41621 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KFU67_RS24530 (41687) | 41687..41971 | + | 285 | Protein_46 | IS6 family transposase IS26 | Transposase |
| KFU67_RS24535 (42161) | 42161..42976 | - | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| KFU67_RS24540 (43127) | 43127..43831 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KFU67_RS24545 (43975) | 43975..44616 | - | 642 | WP_001011939.1 | Chloramphenicol acetyltransferase 2 | ARG |
| KFU67_RS24550 (44766) | 44766..45266 | - | 501 | WP_001239317.1 | hypothetical protein | - |
| KFU67_RS24555 (45346) | 45346..46050 | + | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| KFU67_RS24560 (46498) | 46498..47511 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| KFU67_RS24565 (47667) | 47667..48140 | + | 474 | WP_004201280.1 | Dihydrofolate reductase type 1 | ARG |
| KFU67_RS24570 (48210) | 48210..48914 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KFU67_RS24575 (48968) | 48968..49282 | + | 315 | Protein_55 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| KFU67_RS24580 (49285) | 49285..52251 | + | 2967 | WP_072794601.1 | Tn3 family transposase TnpA_ISPa38 | Transposase |
| KFU67_RS24585 (52330) | 52330..53334 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| KFU67_RS24590 (53606) | 53606..53692 | - | 87 | Protein_58 | Arm DNA-binding domain-containing protein | - |
| KFU67_RS24595 (54022) | 54022..54837 | + | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| KFU67_RS24600 (54898) | 54898..55701 | + | 804 | WP_001082320.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| KFU67_RS24605 (55701) | 55701..56537 | + | 837 | WP_000480972.1 | hypothetical protein | ARG |
| KFU67_RS24610 (56768) | 56768..57628 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| KFU67_RS24615 (57811) | 57811..58368 | - | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| KFU67_RS24620 (58532) | 58532..58672 | + | 141 | WP_020219413.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| KFU67_RS24625 (58790) | 58790..59494 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KFU67_RS24630 (59560) | 59560..60105 | + | 546 | Protein_66 | Tn3 family transposase TnpA_Tn3 | Transposase |
| KFU67_RS24635 (60141) | 60141..60556 | - | 416 | Protein_67 | IS1 family transposase | - |
| KFU67_RS24640 (60805) | 60805..61206 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| KFU67_RS24645 (61139) | 61139..61396 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| KFU67_RS24650 (61489) | 61489..62142 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| KFU67_RS24655 (62240) | 62240..62380 | - | 141 | WP_001333237.1 | hypothetical protein | - |
| KFU67_RS24660 (63081) | 63081..63938 | - | 858 | WP_000774297.1 | incFII family plasmid replication initiator RepA | - |
| KFU67_RS24665 (63931) | 63931..64413 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| KFU67_RS24670 (64406) | 64406..64453 | - | 48 | WP_229471593.1 | hypothetical protein | - |
| KFU67_RS24675 (64444) | 64444..64695 | + | 252 | WP_223195197.1 | replication protein RepA | - |
| KFU67_RS24680 (64712) | 64712..64969 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| KFU67_RS24685 (65253) | 65253..65402 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (65446) | 65446..65507 | + | 62 | NuclAT_1 | - | - |
| - (65446) | 65446..65507 | + | 62 | NuclAT_1 | - | - |
| - (65446) | 65446..65507 | + | 62 | NuclAT_1 | - | - |
| - (65446) | 65446..65507 | + | 62 | NuclAT_1 | - | - |
| KFU67_RS24690 (65763) | 65763..65837 | - | 75 | Protein_78 | endonuclease | - |
| KFU67_RS24695 (66083) | 66083..66295 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| KFU67_RS24700 (66431) | 66431..66991 | - | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| KFU67_RS24705 (67094) | 67094..67954 | - | 861 | WP_000704513.1 | putative protein YcjY | VF |
| KFU67_RS24710 (68013) | 68013..68759 | - | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| KFU67_RS24715 (68779) | 68779..74049 | - | 5271 | WP_000986962.1 | Multifunctional conjugation protein TraI | Relaxase |
| KFU67_RS24720 (74131) | 74131..74358 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| KFU67_RS24725 (74358) | 74358..74756 | + | 399 | WP_000911313.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| KFU67_RS24730 (74765) | 74765..76918 | - | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| KFU67_RS24735 (77171) | 77171..77881 | - | 711 | WP_230133085.1 | conjugal transfer complement resistance protein TraT | - |
| KFU67_RS24740 (77934) | 77934..78431 | - | 498 | WP_000605857.1 | entry exclusion protein | - |
| KFU67_RS24745 (78447) | 78447..81269 | - | 2823 | WP_001007018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| KFU67_RS24750 (81266) | 81266..82639 | - | 1374 | WP_001517790.1 | conjugal transfer pilus assembly protein TraH | - |
| KFU67_RS24755 (82639) | 82639..83019 | - | 381 | WP_001389370.1 | F-type conjugal transfer protein TrbF | - |
| KFU67_RS24760 (83006) | 83006..83347 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| KFU67_RS24765 (83277) | 83277..83822 | - | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| KFU67_RS24770 (83809) | 83809..84093 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| KFU67_RS24775 (84174) | 84174..84488 | + | 315 | WP_001324103.1 | hypothetical protein | - |
| KFU67_RS24780 (84490) | 84490..84837 | - | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| KFU67_RS24785 (84853) | 84853..85596 | - | 744 | WP_001030393.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| KFU67_RS24790 (85589) | 85589..85846 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| KFU67_RS24795 (85873) | 85873..87681 | - | 1809 | WP_000821841.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| KFU67_RS24800 (87678) | 87678..88316 | - | 639 | WP_000777700.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| KFU67_RS24805 (88325) | 88325..89317 | - | 993 | WP_000830183.1 | conjugal transfer pilus assembly protein TraU | - |
| KFU67_RS24810 (89314) | 89314..89946 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| KFU67_RS24815 (89943) | 89943..90329 | - | 387 | WP_000099686.1 | type-F conjugative transfer system protein TrbI | - |
| KFU67_RS24820 (90326) | 90326..92953 | - | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| KFU67_RS24825 (93113) | 93113..93334 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| KFU67_RS24830 (93469) | 93469..93984 | - | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| KFU67_RS24835 (93981) | 93981..94232 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| KFU67_RS24840 (94244) | 94244..94441 | - | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| KFU67_RS24845 (94428) | 94428..95018 | - | 591 | WP_001376242.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| KFU67_RS24850 (95008) | 95008..96435 | - | 1428 | WP_000146685.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| KFU67_RS24855 (96435) | 96435..97163 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| KFU67_RS24860 (97150) | 97150..97716 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| KFU67_RS24865 (97738) | 97738..98049 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| KFU67_RS24870 (98064) | 98064..98429 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| KFU67_RS24875 (98462) | 98462..98863 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| KFU67_RS24880 (98956) | 98956..99645 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| KFU67_RS24885 (99832) | 99832..100215 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| KFU67_RS24890 (100536) | 100536..101138 | + | 603 | WP_072156291.1 | hypothetical protein | VF |
| KFU67_RS24895 (101435) | 101435..102256 | - | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| KFU67_RS24900 (102375) | 102375..102662 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| KFU67_RS24905 (102687) | 102687..102893 | - | 207 | WP_000547971.1 | hypothetical protein | - |
| KFU67_RS24910 (102963) | 102963..103136 | + | 174 | Protein_122 | hypothetical protein | - |
| KFU67_RS24915 (103134) | 103134..103364 | - | 231 | WP_001426396.1 | hypothetical protein | - |
| KFU67_RS24920 (103584) | 103584..103709 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| KFU67_RS24925 (103651) | 103651..103800 | - | 150 | Protein_125 | plasmid maintenance protein Mok | - |
| - (103786) | 103786..104010 | - | 225 | NuclAT_0 | - | - |
| - (103786) | 103786..104010 | - | 225 | NuclAT_0 | - | - |
| - (103786) | 103786..104010 | - | 225 | NuclAT_0 | - | - |
| - (103786) | 103786..104010 | - | 225 | NuclAT_0 | - | - |
| KFU67_RS24930 (103822) | 103822..104010 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| KFU67_RS24935 (103979) | 103979..104741 | - | 763 | Protein_127 | plasmid SOS inhibition protein A | - |
| KFU67_RS24940 (104738) | 104738..105172 | - | 435 | WP_064770609.1 | conjugation system SOS inhibitor PsiB | - |
| KFU67_RS24945 (105227) | 105227..105424 | - | 198 | Protein_129 | hypothetical protein | - |
| KFU67_RS24950 (105452) | 105452..105685 | - | 234 | WP_000005987.1 | DUF905 family protein | - |
| KFU67_RS24955 (105753) | 105753..106292 | - | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| KFU67_RS24960 (106318) | 106318..106524 | - | 207 | WP_000275856.1 | hypothetical protein | - |
| KFU67_RS24965 (106594) | 106594..106674 | + | 81 | Protein_133 | hypothetical protein | - |
| KFU67_RS24970 (106857) | 106857..107026 | - | 170 | Protein_134 | hypothetical protein | - |
| KFU67_RS24975 (107663) | 107663..108634 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| KFU67_RS24980 (108634) | 108634..109800 | - | 1167 | WP_001238646.1 | Sporulation initiation inhibitor protein Soj | VF |
| KFU67_RS24990 (111282) | 111282..113483 | - | 2202 | WP_000973520.1 | Ferric aerobactin receptor | VF |
| KFU67_RS24995 (113509) | 113509..114842 | - | 1334 | Protein_139 | L-lysine N6-monooxygenase | VF |
| KFU67_RS25000 (114839) | 114839..116581 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| KFU67_RS25005 (116581) | 116581..117528 | - | 948 | WP_000011910.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| KFU67_RS25010 (117529) | 117529..119253 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| KFU67_RS25015 (119389) | 119389..120582 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| KFU67_RS25020 (120962) | 120962..121342 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| KFU67_RS25025 (121683) | 121683..122096 | - | 414 | Protein_145 | phosphopyruvate hydratase | - |
| KFU67_RS25030 (122094) | 122094..122351 | + | 258 | Protein_146 | transposase | - |
| KFU67_RS25035 (122585) | 122585..123442 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| KFU67_RS25040 (123439) | 123439..124296 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| KFU67_RS25045 (124293) | 124293..125120 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| KFU67_RS25050 (125120) | 125120..126034 | - | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| KFU67_RS25055 (126390) | 126390..127087 | + | 698 | WP_223155668.1 | IS1 family transposase IS1S | Transposase |
| KFU67_RS25060 (127267) | 127267..127780 | - | 514 | Protein_152 | DUF4113 domain-containing protein | - |
| KFU67_RS25065 (127841) | 127841..127945 | - | 105 | Protein_153 | AAA family ATPase | - |
| KFU67_RS25070 (127947) | 127947..128270 | - | 324 | Protein_154 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|