MGE detailed information
MGE type: Conjugative plasmid MGE length: 116735 bp
Accession: NZ_CP072859 Location: 1..116735 Organism: Escherichia coli strain 184/2aE Replicon: plasmid pEc184__IncF
Accession: NZ_CP072859 Location: 1..116735 Organism: Escherichia coli strain 184/2aE Replicon: plasmid pEc184__IncF
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| J9158_RS22890 (1) | 1..978 | + | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| J9158_RS22895 (1263) | 1263..2003 | - | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| J9158_RS22900 (2124) | 2124..2306 | - | 183 | WP_042065278.1 | hypothetical protein | - |
| J9158_RS24125 (2373) | 2373..2662 | - | 290 | Protein_3 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| J9158_RS22905 (2649) | 2649..2917 | - | 269 | Protein_4 | type II toxin-antitoxin system ParD family antitoxin | - |
| J9158_RS22910 (3449) | 3449..4618 | + | 1170 | WP_023909118.1 | hypothetical protein | - |
| J9158_RS22915 (4651) | 4651..4779 | + | 129 | Protein_6 | IS481 family transposase | - |
| J9158_RS22920 (4814) | 4814..5002 | - | 189 | Protein_7 | hypothetical protein | - |
| J9158_RS22925 (5050) | 5050..5747 | + | 698 | WP_103215986.1 | IS1 family transposase IS1R | Transposase |
| J9158_RS22930 (5765) | 5765..5890 | + | 126 | Protein_9 | IS4 family transposase | - |
| J9158_RS22935 (5900) | 5900..6316 | - | 417 | WP_000275180.1 | Transposon Tn10 TetD protein | VF |
| J9158_RS22940 (6404) | 6404..6997 | + | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| J9158_RS22945 (7110) | 7110..8315 | - | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| J9158_RS22950 (8397) | 8397..9020 | + | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| J9158_RS22955 (8998) | 8998..9117 | - | 120 | Protein_14 | transcriptional regulator | - |
| J9158_RS22965 (10254) | 10254..11234 | - | 981 | WP_031311978.1 | IS5 family transposase ISKpn26 | Transposase |
| J9158_RS22970 (11308) | 11308..11967 | + | 660 | WP_000412211.1 | Chloramphenicol acetyltransferase | ARG |
| J9158_RS22975 (12168) | 12168..12545 | - | 378 | WP_000656305.1 | GNAT family N-acetyltransferase | - |
| J9158_RS22980 (12856) | 12856..13860 | - | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| J9158_RS22985 (13939) | 13939..16905 | - | 2967 | WP_023909098.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| J9158_RS22990 (16908) | 16908..17468 | - | 561 | WP_000147567.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| J9158_RS22995 (17594) | 17594..17944 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| J9158_RS23000 (18147) | 18147..19160 | - | 1014 | WP_000845039.1 | IS91 family transposase ISAzo26 | Transposase |
| J9158_RS23005 (19555) | 19555..21090 | + | 1536 | WP_064760451.1 | Antiseptic resistance protein | ARG |
| J9158_RS23010 (21118) | 21118..21504 | - | 387 | Protein_25 | mechanosensitive ion channel | - |
| J9158_RS23015 (21743) | 21743..23227 | - | 1485 | WP_022742855.1 | IS91 family transposase ISVsa3 | Transposase |
| J9158_RS23020 (23502) | 23502..23855 | - | 354 | Protein_27 | 60 kDa chaperonin | VF |
| J9158_RS23025 (23856) | 23856..24155 | - | 300 | Protein_28 | 60 kDa chaperonin | VF |
| J9158_RS23030 (24300) | 24300..24797 | + | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| J9158_RS23035 (24909) | 24909..25199 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| J9158_RS23040 (25205) | 25205..26043 | + | 839 | Protein_31 | Streptomycin 3''-adenylyltransferase | ARG |
| J9158_RS23045 (26160) | 26160..26507 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| J9158_RS23050 (26501) | 26501..27340 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| J9158_RS23055 (27468) | 27468..27671 | + | 204 | WP_000376616.1 | hypothetical protein | - |
| J9158_RS23060 (27827) | 27827..29032 | + | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| J9158_RS23065 (29043) | 29043..29348 | + | 306 | WP_000130000.1 | hypothetical protein | Relaxase |
| J9158_RS23070 (29392) | 29392..29457 | + | 66 | Protein_37 | EAL domain-containing protein | - |
| J9158_RS23075 (29575) | 29575..30339 | + | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| J9158_RS23080 (30832) | 30832..31416 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| J9158_RS23085 (31416) | 31416..32654 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| J9158_RS23090 (32651) | 32651..33565 | - | 915 | WP_023063803.1 | hypothetical protein | ARG |
| J9158_RS23095 (33687) | 33687..34391 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| J9158_RS23100 (34526) | 34526..34621 | + | 96 | WP_013362819.1 | 23S rRNA methyltransferase attenuation leader peptide | - |
| J9158_RS23105 (34747) | 34747..35484 | + | 738 | WP_013362818.1 | rRNA adenine N-6-methyltransferase | ARG |
| J9158_RS23115 (36114) | 36114..36563 | + | 450 | WP_073518795.1 | hypothetical protein | - |
| J9158_RS23120 (36524) | 36524..36865 | + | 342 | WP_023909256.1 | 60 kDa chaperonin 2 | VF |
| J9158_RS23125 (37140) | 37140..38531 | + | 1392 | Protein_47 | IS91 family transposase ISVsa3 | Transposase |
| J9158_RS23130 (38585) | 38585..39289 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| J9158_RS23135 (39355) | 39355..39900 | + | 546 | Protein_49 | Tn3 family transposase TnpA_Tn3 | Transposase |
| J9158_RS23140 (39936) | 39936..40351 | - | 416 | Protein_50 | IS1-like element IS1A family transposase | - |
| J9158_RS23145 (40600) | 40600..41001 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| J9158_RS23150 (40934) | 40934..41191 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| J9158_RS23155 (41284) | 41284..41937 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| J9158_RS23160 (42876) | 42876..43733 | - | 858 | WP_000130646.1 | incFII family plasmid replication initiator RepA | - |
| J9158_RS23165 (43726) | 43726..43800 | - | 75 | WP_014966221.1 | RepA leader peptide Tap | - |
| J9158_RS23175 (44162) | 44162..45703 | + | 1542 | WP_002431311.1 | IS21 family transposase ISEc12 | Transposase |
| J9158_RS23180 (45718) | 45718..46464 | + | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| J9158_RS23185 (46624) | 46624..46878 | - | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| J9158_RS23190 (47175) | 47175..47309 | - | 135 | WP_023144756.1 | Hok/Gef family protein | Toxin Detail |
| - (47354) | 47354..47414 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - (47354) | 47354..47414 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - (47354) | 47354..47414 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| - (47354) | 47354..47414 | + | 61 | NuclAT_2 | - | Antitoxin Detail |
| J9158_RS23195 (47381) | 47381..47667 | - | 287 | Protein_60 | DUF2726 domain-containing protein | - |
| J9158_RS23200 (48180) | 48180..48392 | - | 213 | WP_013023861.1 | hypothetical protein | - |
| J9158_RS23205 (48523) | 48523..49083 | - | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| J9158_RS23210 (49138) | 49138..49884 | - | 747 | WP_023909066.1 | conjugal transfer pilus acetylase TraX | - |
| J9158_RS23215 (49904) | 49904..55174 | - | 5271 | WP_001617867.1 | Multifunctional conjugation protein TraI | Relaxase |
| J9158_RS23220 (55174) | 55174..57372 | - | 2199 | WP_024623315.1 | type IV conjugative transfer system coupling protein TraD | - |
| J9158_RS23225 (57369) | 57369..57887 | - | 519 | Protein_66 | hypothetical protein | - |
| J9158_RS23235 (58664) | 58664..59296 | - | 633 | Protein_68 | conjugal transfer protein TraN | - |
| J9158_RS23240 (59293) | 59293..59931 | - | 639 | WP_001080259.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| J9158_RS23245 (59940) | 59940..60245 | - | 306 | WP_000224413.1 | hypothetical protein | - |
| J9158_RS23250 (60275) | 60275..61267 | - | 993 | WP_000830190.1 | conjugal transfer pilus assembly protein TraU | - |
| J9158_RS23255 (61264) | 61264..61896 | - | 633 | WP_001203727.1 | type-F conjugative transfer system protein TraW | - |
| J9158_RS23260 (61893) | 61893..62279 | - | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| J9158_RS23265 (62276) | 62276..64903 | - | 2628 | WP_001064258.1 | type IV secretion system protein TraC | - |
| J9158_RS23270 (65063) | 65063..65284 | - | 222 | WP_001278694.1 | conjugal transfer protein TraR | - |
| J9158_RS23275 (65419) | 65419..65934 | - | 516 | WP_000809886.1 | type IV conjugative transfer system lipoprotein TraV | - |
| J9158_RS23280 (65934) | 65934..66245 | - | 312 | WP_001057272.1 | conjugal transfer protein TrbD | - |
| J9158_RS23285 (66232) | 66232..66798 | - | 567 | WP_000896601.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| J9158_RS23290 (66788) | 66788..68239 | - | 1452 | WP_000146687.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| J9158_RS23295 (68239) | 68239..68967 | - | 729 | WP_001230808.1 | type-F conjugative transfer system secretin TraK | - |
| J9158_RS23300 (68954) | 68954..69520 | - | 567 | WP_000399791.1 | type IV conjugative transfer system protein TraE | - |
| J9158_RS23305 (69542) | 69542..69853 | - | 312 | WP_000012107.1 | type IV conjugative transfer system protein TraL | - |
| J9158_RS23310 (69858) | 69858..70220 | - | 363 | WP_000338606.1 | type IV conjugative transfer system pilin TraA | - |
| J9158_RS23315 (70254) | 70254..70481 | - | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| J9158_RS23320 (70569) | 70569..71246 | - | 678 | WP_001348626.1 | PAS domain-containing protein | - |
| J9158_RS23325 (71380) | 71380..71763 | - | 384 | WP_001151566.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| J9158_RS23330 (72106) | 72106..72696 | + | 591 | WP_001376243.1 | hypothetical protein | VF |
| J9158_RS23335 (72993) | 72993..73814 | - | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| J9158_RS23340 (73933) | 73933..74220 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| J9158_RS23345 (74245) | 74245..74451 | - | 207 | WP_000275859.1 | hypothetical protein | - |
| J9158_RS24130 (74521) | 74521..74694 | + | 174 | Protein_91 | hypothetical protein | - |
| J9158_RS24135 (74692) | 74692..74922 | - | 231 | WP_001426396.1 | hypothetical protein | - |
| J9158_RS23350 (75142) | 75142..75267 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| J9158_RS24140 (75209) | 75209..75358 | - | 150 | Protein_94 | plasmid maintenance protein Mok | - |
| - (75344) | 75344..75382 | - | 39 | NuclAT_1 | - | Antitoxin Detail |
| - (75344) | 75344..75382 | - | 39 | NuclAT_1 | - | Antitoxin Detail |
| - (75344) | 75344..75382 | - | 39 | NuclAT_1 | - | Antitoxin Detail |
| - (75344) | 75344..75382 | - | 39 | NuclAT_1 | - | Antitoxin Detail |
| - (76822) | 76822..76924 | - | 103 | NuclAT_0 | - | - |
| - (76822) | 76822..76924 | - | 103 | NuclAT_0 | - | - |
| - (76822) | 76822..76924 | - | 103 | NuclAT_0 | - | - |
| - (76822) | 76822..76924 | - | 103 | NuclAT_0 | - | - |
| J9158_RS23360 (76893) | 76893..77655 | - | 763 | Protein_96 | plasmid SOS inhibition protein A | - |
| J9158_RS23365 (77652) | 77652..78086 | - | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| J9158_RS23370 (78155) | 78155..80178 | - | 2024 | Protein_98 | ParB/RepB/Spo0J family partition protein | - |
| J9158_RS23375 (80239) | 80239..80472 | - | 234 | WP_000006003.1 | DUF905 family protein | - |
| J9158_RS23380 (80530) | 80530..81015 | - | 486 | WP_031311812.1 | single-stranded DNA-binding protein | - |
| J9158_RS23385 (81165) | 81165..83066 | - | 1902 | WP_000936285.1 | group II intron reverse transcriptase/maturase | - |
| J9158_RS24145 (84020) | 84020..84475 | + | 456 | Protein_102 | hypothetical protein | - |
| J9158_RS23390 (84561) | 84561..84659 | - | 99 | Protein_103 | class I SAM-dependent methyltransferase | - |
| J9158_RS23395 (84751) | 84751..85979 | + | 1229 | WP_113708090.1 | IS3 family transposase IS2 | Transposase |
| J9158_RS23400 (85993) | 85993..86460 | - | 468 | Protein_105 | class I SAM-dependent methyltransferase | - |
| J9158_RS23405 (86507) | 86507..87868 | - | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| J9158_RS23410 (87920) | 87920..88150 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| J9158_RS23415 (89188) | 89188..89379 | - | 192 | WP_001027493.1 | hypothetical protein | - |
| J9158_RS23420 (89376) | 89376..89798 | - | 423 | WP_000271762.1 | DUF1380 family protein | - |
| J9158_RS23425 (89845) | 89845..90270 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| J9158_RS23430 (90688) | 90688..91464 | - | 777 | WP_001383963.1 | hypothetical protein | - |
| J9158_RS23435 (91515) | 91515..91949 | - | 435 | WP_000274503.1 | DUF1380 family protein | - |
| J9158_RS23440 (91963) | 91963..92184 | - | 222 | WP_001104880.1 | hypothetical protein | - |
| J9158_RS23445 (92185) | 92185..92868 | - | 684 | WP_000086185.1 | DNA methylase | - |
| J9158_RS23450 (92945) | 92945..93256 | - | 312 | WP_249384342.1 | hypothetical protein | - |
| J9158_RS23455 (93253) | 93253..94155 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| J9158_RS23460 (95022) | 95022..95993 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| J9158_RS23465 (95993) | 95993..97159 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| J9158_RS23470 (97747) | 97747..98502 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| J9158_RS23475 (99276) | 99276..100082 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| J9158_RS23480 (100083) | 100083..100388 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| J9158_RS23485 (100390) | 100390..100608 | - | 219 | WP_023909027.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| J9158_RS23490 (101242) | 101242..101439 | + | 198 | WP_000215657.1 | hypothetical protein | - |
| J9158_RS23495 (101436) | 101436..101720 | - | 285 | WP_000642771.1 | hypothetical protein | - |
| J9158_RS23500 (101740) | 101740..102873 | - | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| J9158_RS23505 (103136) | 103136..106255 | - | 3120 | WP_023909028.1 | hypothetical protein | - |
| J9158_RS23510 (106562) | 106562..106792 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| J9158_RS23515 (106789) | 106789..107205 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| J9158_RS23520 (107367) | 107367..109505 | - | 2139 | WP_000350635.1 | AAA family ATPase | - |
| J9158_RS23525 (109970) | 109970..110965 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| J9158_RS23530 (111008) | 111008..111901 | + | 894 | WP_001553853.1 | S-4TM family putative pore-forming effector | - |
| J9158_RS23540 (112764) | 112764..114248 | - | 1485 | WP_174220535.1 | type I restriction-modification system subunit M | - |
| J9158_RS23545 (114431) | 114431..114652 | + | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| J9158_RS23550 (114652) | 114652..115032 | + | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | - |
| J9158_RS23555 (115037) | 115037..115216 | + | 180 | WP_001513661.1 | hypothetical protein | - |
| J9158_RS23560 (115244) | 115244..115522 | + | 279 | Protein_137 | pdcB | - |
| J9158_RS23565 (115527) | 115527..115940 | + | 414 | Protein_138 | IS3 family transposase ISLad1 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|