MGE detailed information
MGE type: Conjugative plasmid MGE length: 102746 bp
Accession: NZ_CP072557 Location: 1..102746 Organism: Klebsiella pneumoniae strain KP2648 Replicon: plasmid pKP2648-KPC
Accession: NZ_CP072557 Location: 1..102746 Organism: Klebsiella pneumoniae strain KP2648 Replicon: plasmid pKP2648-KPC
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| J7339_RS27435 (1142) | 1142..2629 | - | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| J7339_RS27440 (3036) | 3036..3467 | + | 432 | WP_001568036.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| J7339_RS27445 (3467) | 3467..4738 | + | 1272 | WP_013214011.1 | Y-family DNA polymerase | - |
| J7339_RS27450 (4820) | 4820..5794 | - | 975 | WP_011977819.1 | ParB family protein | - |
| J7339_RS27455 (5794) | 5794..6999 | - | 1206 | WP_011977818.1 | AAA family ATPase | - |
| J7339_RS27460 (8109) | 8109..8975 | - | 867 | WP_004118283.1 | replication initiation protein | - |
| J7339_RS27465 (9511) | 9511..9624 | + | 114 | WP_014343462.1 | hypothetical protein | - |
| J7339_RS27470 (9753) | 9753..10010 | + | 258 | WP_013214010.1 | hypothetical protein | - |
| J7339_RS27475 (10056) | 10056..10835 | - | 780 | WP_013214009.1 | site-specific integrase | - |
| J7339_RS27480 (11019) | 11019..12023 | - | 1005 | WP_011977814.1 | hypothetical protein | - |
| J7339_RS27485 (12053) | 12053..12256 | - | 204 | WP_011977813.1 | hypothetical protein | - |
| J7339_RS27490 (12302) | 12302..12823 | - | 522 | WP_013214008.1 | hypothetical protein | - |
| J7339_RS27495 (12881) | 12881..13273 | - | 393 | WP_011977811.1 | hypothetical protein | - |
| J7339_RS27500 (13310) | 13310..14254 | - | 945 | WP_011977810.1 | hypothetical protein | - |
| J7339_RS27505 (14415) | 14415..14876 | - | 462 | WP_014343465.1 | hypothetical protein | - |
| J7339_RS27510 (14833) | 14833..15063 | + | 231 | WP_001261282.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| J7339_RS27515 (15060) | 15060..15476 | + | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| J7339_RS27520 (15550) | 15550..17112 | + | 1563 | WP_004206609.1 | AAA family ATPase | - |
| J7339_RS27525 (17097) | 17097..18119 | + | 1023 | WP_000361404.1 | helicase UvrD | - |
| J7339_RS27530 (18375) | 18375..19072 | + | 698 | WP_223174630.1 | IS1 family transposase | - |
| J7339_RS27535 (19101) | 19101..19373 | + | 273 | Protein_21 | transposase | - |
| J7339_RS27540 (19653) | 19653..20657 | - | 1005 | WP_000427619.1 | IS110-like element IS5075 family transposase | - |
| J7339_RS27545 (20736) | 20736..21170 | - | 435 | WP_000429836.1 | Hg(II)-responsive transcriptional regulator | - |
| J7339_RS27550 (21242) | 21242..21592 | + | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| J7339_RS27555 (21606) | 21606..21881 | + | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| J7339_RS27560 (21917) | 21917..22339 | + | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| J7339_RS27565 (22391) | 22391..24085 | + | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| J7339_RS27570 (24103) | 24103..24465 | + | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| J7339_RS27575 (24462) | 24462..24698 | + | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| J7339_RS27580 (24734) | 24734..25402 | + | 669 | WP_001300294.1 | EAL domain-containing protein | - |
| J7339_RS27585 (25477) | 25477..26649 | + | 1173 | Protein_31 | transposase | - |
| J7339_RS27590 (26714) | 26714..27418 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| J7339_RS27595 (27470) | 27470..27931 | + | 462 | Protein_33 | recombinase family protein | - |
| J7339_RS27600 (28054) | 28054..29034 | + | 981 | WP_013213985.1 | IS481-like element ISKpn27 family transposase | - |
| J7339_RS27605 (29310) | 29310..30191 | + | 882 | WP_004199234.1 | carbapenem-hydrolyzing class A beta-lactamase KPC-2 | - |
| J7339_RS27610 (30441) | 30441..31322 | - | 882 | Protein_36 | IS1182-like element ISKpn6 family transposase | - |
| J7339_RS27615 (31426) | 31426..31722 | - | 297 | WP_013213987.1 | transcriptional regulator | - |
| J7339_RS27620 (31768) | 31768..31923 | - | 156 | WP_013213988.1 | hypothetical protein | - |
| J7339_RS27625 (32051) | 32051..32476 | - | 426 | WP_013213989.1 | antirestriction protein | - |
| J7339_RS27630 (32587) | 32587..32865 | - | 279 | WP_013213990.1 | hypothetical protein | - |
| J7339_RS27635 (33399) | 33399..34016 | - | 618 | Protein_41 | replication protein | - |
| J7339_RS27640 (34408) | 34408..34968 | + | 561 | WP_001161490.1 | recombinase family protein | - |
| J7339_RS27645 (34972) | 34972..37938 | + | 2967 | WP_001138014.1 | Tn3-like element TnAs1 family transposase | - |
| J7339_RS27650 (37974) | 37974..38042 | - | 69 | Protein_44 | IS6 family transposase | - |
| J7339_RS27655 (38179) | 38179..39039 | + | 861 | WP_004176269.1 | broad-spectrum class A beta-lactamase SHV-11 | - |
| J7339_RS27660 (39060) | 39060..39821 | - | 762 | WP_002210513.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| J7339_RS27665 (40082) | 40082..40984 | + | 903 | WP_002903955.1 | NAD(P)-dependent oxidoreductase | - |
| J7339_RS27670 (40996) | 40996..42248 | + | 1253 | Protein_48 | four-carbon acid sugar kinase family protein | - |
| J7339_RS27675 (42241) | 42241..42564 | + | 324 | Protein_49 | class II aldolase/adducin family protein | - |
| J7339_RS27680 (42618) | 42618..43322 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| J7339_RS27685 (43386) | 43386..43646 | - | 261 | Protein_51 | chemotaxis protein | - |
| J7339_RS27690 (43709) | 43709..44413 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| J7339_RS27695 (44447) | 44447..49582 | - | 5136 | WP_071177725.1 | conjugative transfer relaxase/helicase TraI | - |
| J7339_RS27700 (49582) | 49582..51798 | - | 2217 | WP_059274178.1 | type IV conjugative transfer system coupling protein TraD | - |
| J7339_RS27705 (51849) | 51849..52586 | - | 738 | WP_015059020.1 | hypothetical protein | - |
| J7339_RS27710 (52789) | 52789..53520 | - | 732 | WP_021559024.1 | conjugal transfer complement resistance protein TraT | - |
| J7339_RS27715 (53545) | 53545..54066 | - | 522 | WP_000632668.1 | conjugal transfer entry exclusion protein TraS | - |
| J7339_RS27720 (54099) | 54099..56915 | - | 2817 | WP_015059018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| J7339_RS27725 (56912) | 56912..58285 | - | 1374 | WP_000944325.1 | conjugal transfer pilus assembly protein TraH | - |
| J7339_RS27730 (58272) | 58272..58664 | - | 393 | WP_000126338.1 | F-type conjugal transfer protein TrbF | - |
| J7339_RS27735 (58618) | 58618..58932 | - | 315 | WP_001384255.1 | P-type conjugative transfer protein TrbJ | - |
| J7339_RS27740 (58922) | 58922..59467 | - | 546 | WP_000059817.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| J7339_RS27745 (59454) | 59454..59690 | - | 237 | WP_000270010.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| J7339_RS27750 (59851) | 59851..60600 | - | 750 | WP_072354014.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| J7339_RS27755 (60587) | 60587..60844 | - | 258 | WP_053913405.1 | conjugal transfer protein TrbE | - |
| J7339_RS27760 (60871) | 60871..62112 | - | 1242 | Protein_66 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| J7339_RS27765 (62165) | 62165..62869 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| J7339_RS27770 (63149) | 63149..64117 | - | 969 | WP_013362812.1 | IS5-like element IS903B family transposase | - |
| J7339_RS27775 (64152) | 64152..65027 | - | 876 | WP_013188475.1 | extended-spectrum class A beta-lactamase CTX-M-65 | - |
| J7339_RS27780 (65277) | 65277..65468 | - | 192 | Protein_70 | IS1380 family transposase | - |
| J7339_RS27785 (65538) | 65538..66242 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| J7339_RS27790 (66308) | 66308..66853 | + | 546 | Protein_72 | Tn3 family transposase | - |
| J7339_RS27795 (66889) | 66889..67304 | - | 416 | Protein_73 | IS1-like element IS1B family transposase | - |
| J7339_RS27800 (67553) | 67553..67954 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| J7339_RS27805 (67887) | 67887..68144 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| J7339_RS27810 (68237) | 68237..68890 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| J7339_RS27815 (69829) | 69829..70686 | - | 858 | WP_032495102.1 | incFII family plasmid replication initiator RepA | - |
| J7339_RS29305 (70679) | 70679..70753 | - | 75 | WP_001375168.1 | RepA leader peptide Tap | - |
| J7339_RS27825 (70998) | 70998..71246 | - | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
| J7339_RS27830 (71530) | 71530..71679 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (71724) | 71724..71783 | + | 60 | NuclAT_0 | - | Antitoxin Detail |
| - (71724) | 71724..71783 | + | 60 | NuclAT_0 | - | Antitoxin Detail |
| - (71724) | 71724..71783 | + | 60 | NuclAT_0 | - | Antitoxin Detail |
| - (71724) | 71724..71783 | + | 60 | NuclAT_0 | - | Antitoxin Detail |
| J7339_RS27835 (71984) | 71984..72316 | - | 333 | WP_152916585.1 | hypothetical protein | - |
| J7339_RS27840 (72378) | 72378..72977 | - | 600 | WP_032083981.1 | PIN domain-containing protein | - |
| J7339_RS27845 (73363) | 73363..73563 | - | 201 | WP_015059022.1 | hypothetical protein | - |
| J7339_RS27850 (73695) | 73695..74255 | - | 561 | WP_000139328.1 | fertility inhibition protein FinO | - |
| J7339_RS27855 (74310) | 74310..75056 | - | 747 | WP_000205770.1 | conjugal transfer pilus acetylase TraX | - |
| J7339_RS27860 (75076) | 75076..75276 | - | 201 | WP_072354025.1 | hypothetical protein | - |
| J7339_RS27865 (75301) | 75301..76005 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| J7339_RS27870 (76060) | 76060..76425 | - | 366 | Protein_88 | type IV conjugative transfer system protein TraE | - |
| J7339_RS27875 (76445) | 76445..76750 | - | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| J7339_RS27880 (76764) | 76764..77132 | - | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| J7339_RS27885 (77194) | 77194..77400 | - | 207 | WP_171773970.1 | TraY domain-containing protein | - |
| J7339_RS27890 (77515) | 77515..78252 | - | 738 | WP_154244330.1 | conjugal transfer protein TrbJ | - |
| J7339_RS27895 (78452) | 78452..78868 | - | 417 | WP_014343494.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| J7339_RS27900 (79259) | 79259..79744 | + | 486 | WP_014343495.1 | transglycosylase SLT domain-containing protein | - |
| J7339_RS27905 (79777) | 79777..80106 | - | 330 | WP_013214015.1 | DUF5983 family protein | - |
| J7339_RS27910 (80139) | 80139..80960 | - | 822 | WP_004152492.1 | DUF932 domain-containing protein | - |
| J7339_RS27915 (81789) | 81789..81893 | - | 105 | Protein_97 | transcriptional regulator | - |
| J7339_RS27920 (81897) | 81897..82175 | - | 279 | WP_004152721.1 | helix-turn-helix transcriptional regulator | - |
| J7339_RS27925 (82165) | 82165..82485 | - | 321 | WP_014343498.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| J7339_RS27930 (82566) | 82566..82790 | - | 225 | WP_014343499.1 | hypothetical protein | - |
| J7339_RS27935 (82801) | 82801..83013 | - | 213 | WP_014343500.1 | hypothetical protein | - |
| J7339_RS27940 (83074) | 83074..83430 | - | 357 | WP_014343501.1 | hypothetical protein | - |
| J7339_RS27945 (84271) | 84271..84588 | - | 318 | WP_014343505.1 | hypothetical protein | - |
| J7339_RS27950 (84603) | 84603..84953 | - | 351 | WP_040245917.1 | hypothetical protein | - |
| J7339_RS27955 (84950) | 84950..85222 | - | 273 | WP_040245921.1 | hypothetical protein | - |
| J7339_RS27960 (85915) | 85915..86013 | - | 99 | WP_159224797.1 | Hok/Gef family protein | - |
| J7339_RS27965 (85988) | 85988..86044 | - | 57 | Protein_107 | modulator protein | - |
| J7339_RS27970 (86145) | 86145..87218 | + | 1074 | WP_013609528.1 | IS481-like element ISKpn28 family transposase | - |
| J7339_RS27975 (87402) | 87402..87776 | - | 375 | WP_014343510.1 | hypothetical protein | - |
| J7339_RS27980 (87832) | 87832..88158 | - | 327 | WP_013023807.1 | hypothetical protein | - |
| J7339_RS27985 (88155) | 88155..88883 | - | 729 | WP_001568058.1 | plasmid SOS inhibition protein A | - |
| J7339_RS27990 (88880) | 88880..89311 | - | 432 | WP_001568057.1 | conjugation system SOS inhibitor PsiB | - |
| J7339_RS27995 (89356) | 89356..91413 | - | 2058 | WP_015493064.1 | ParB/RepB/Spo0J family partition protein | - |
| J7339_RS28000 (91483) | 91483..91731 | - | 249 | WP_001568055.1 | DUF905 domain-containing protein | - |
| J7339_RS28005 (91780) | 91780..92322 | - | 543 | WP_014343512.1 | single-stranded DNA-binding protein | - |
| J7339_RS28010 (93155) | 93155..93718 | - | 564 | WP_014343514.1 | methyltransferase | - |
| J7339_RS28015 (93766) | 93766..95121 | - | 1356 | WP_014343515.1 | DUF3560 domain-containing protein | - |
| J7339_RS28020 (95173) | 95173..95403 | - | 231 | WP_001568051.1 | hypothetical protein | - |
| J7339_RS28025 (95495) | 95495..95722 | - | 228 | WP_001568050.1 | hypothetical protein | - |
| J7339_RS28030 (96402) | 96402..96722 | - | 321 | WP_001568049.1 | hypothetical protein | - |
| J7339_RS28035 (96757) | 96757..97011 | - | 255 | WP_011977779.1 | DNA polymerase III subunit theta | - |
| J7339_RS28040 (97199) | 97199..97390 | - | 192 | WP_001568047.1 | hypothetical protein | - |
| J7339_RS28045 (97433) | 97433..97939 | - | 507 | WP_013214014.1 | antirestriction protein ArdA | - |
| J7339_RS28050 (97982) | 97982..98410 | - | 429 | WP_001568045.1 | antirestriction protein | - |
| J7339_RS28055 (99091) | 99091..99858 | - | 768 | WP_013214013.1 | hypothetical protein | - |
| J7339_RS28060 (99912) | 99912..100331 | - | 420 | WP_001568043.1 | DUF1380 domain-containing protein | - |
| J7339_RS28065 (100341) | 100341..100562 | - | 222 | WP_001568042.1 | hypothetical protein | - |
| J7339_RS28070 (100562) | 100562..101263 | - | 702 | WP_001568041.1 | DNA methylase | - |
| J7339_RS28075 (101335) | 101335..101504 | - | 170 | Protein_129 | hypothetical protein | - |
| J7339_RS28080 (101700) | 101700..101930 | - | 231 | WP_001568040.1 | hypothetical protein | - |
| J7339_RS28085 (101993) | 101993..102664 | - | 672 | WP_013214012.1 | plasmid partitioning/stability family protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|